Click here to switch to the map view.

The map label for this gene is tesB [H]

Identifier: 182680869

GI number: 182680869

Start: 390584

End: 391435

Strand: Reverse

Name: tesB [H]

Synonym: XfasM23_0306

Alternate gene names: 182680869

Gene position: 391435-390584 (Counterclockwise)

Preceding gene: 182680870

Following gene: 182680868

Centisome position: 15.44

GC content: 52.93

Gene sequence:

>852_bases
ATGCTCTCGCTGGAAAGGCTTGAAGATAATCTGTTCCGTGGTCAAAACCGTGACATTGGAACGAAATATGTGTTTGGTGG
GCAAATACTTGCCCAAGCCCTGGCCGCAGCGCAAAACACCATTGAAAACAGCCGCATTGCGCACTCCCTACATGCCTACT
TTCTACGCACTGGCAACATCCAACAACCGATTATCTATAACGTAGAACGCACTCGGGACGGCAAAAGCTTCTCATTACGC
CGCGTCACCGCAATCCAGCACGGTCAAGTAATCTTTTTCTGCACGGCATCATTCCAGGAACGCGAAGACGGCGCTGAACA
CCAAACCAACATGCCTGCAGTCCCTCCCCCTGAAGACATCGCACCAACCCCACCGCTGCCTCCGGAAACACTAGCCAGAA
TGCCACCCCAAATGCAAACCTGGCTCAACCTGAGCGGACAATTTGAATTTCGCCGCGTGCCGCCCAACAACACACTGGAT
TTGCAGAAACATTCAGCATTCCAACACTTGTGGCTACGCATGAACGCCCCACTTGGTGACCGCATTGAATTGCATCAGAT
ATTGCTAACCTACGCATCCGACTTCCAACTCCTCGAAACAGCCACCTCACGACATGGAATCAACTACCACACACCACAAG
TACAGATGGCCTCACTGGACCATGCACTGTGGTTCCACCGCCCATTCCGCATTGATGACTGGTTGTTATATACGCTTGAA
AGCCCCACCGCACAGGGCGCCCGCGGATTGGCCCGCGGACAATTTTTCACCCGCAATGGCGTATTGATCGCCAACACCGC
CCAGGAAGGACTCATGCGCATGACCAACCATACAACGCCCTCCAAGGATTAA

Upstream 100 bases:

>100_bases
TAAATCCCATCCGCTATAATGAATTACCCATCACAACTATTCAGGCCACATTATCTTGCCAACGCATACCACATCTAACG
CATCCTCCGAATGGACCAAA

Downstream 100 bases:

>100_bases
CCGATGCGTGGCATCTTTACCAGCCAGCGTGTGGAAACAGTCGAAGGTGTCGCTGCACTCCTCAACGAAGCCGACATCCA
AGTAAAAATCAGCCATCAAC

Product: palmitoyl-CoA hydrolase

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MLSLERLEDNLFRGQNRDIGTKYVFGGQILAQALAAAQNTIENSRIAHSLHAYFLRTGNIQQPIIYNVERTRDGKSFSLR
RVTAIQHGQVIFFCTASFQEREDGAEHQTNMPAVPPPEDIAPTPPLPPETLARMPPQMQTWLNLSGQFEFRRVPPNNTLD
LQKHSAFQHLWLRMNAPLGDRIELHQILLTYASDFQLLETATSRHGINYHTPQVQMASLDHALWFHRPFRIDDWLLYTLE
SPTAQGARGLARGQFFTRNGVLIANTAQEGLMRMTNHTTPSKD

Sequences:

>Translated_283_residues
MLSLERLEDNLFRGQNRDIGTKYVFGGQILAQALAAAQNTIENSRIAHSLHAYFLRTGNIQQPIIYNVERTRDGKSFSLR
RVTAIQHGQVIFFCTASFQEREDGAEHQTNMPAVPPPEDIAPTPPLPPETLARMPPQMQTWLNLSGQFEFRRVPPNNTLD
LQKHSAFQHLWLRMNAPLGDRIELHQILLTYASDFQLLETATSRHGINYHTPQVQMASLDHALWFHRPFRIDDWLLYTLE
SPTAQGARGLARGQFFTRNGVLIANTAQEGLMRMTNHTTPSKD
>Mature_283_residues
MLSLERLEDNLFRGQNRDIGTKYVFGGQILAQALAAAQNTIENSRIAHSLHAYFLRTGNIQQPIIYNVERTRDGKSFSLR
RVTAIQHGQVIFFCTASFQEREDGAEHQTNMPAVPPPEDIAPTPPLPPETLARMPPQMQTWLNLSGQFEFRRVPPNNTLD
LQKHSAFQHLWLRMNAPLGDRIELHQILLTYASDFQLLETATSRHGINYHTPQVQMASLDHALWFHRPFRIDDWLLYTLE
SPTAQGARGLARGQFFTRNGVLIANTAQEGLMRMTNHTTPSKD

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=294, Percent_Identity=39.1156462585034, Blast_Score=214, Evalue=6e-56,
Organism=Escherichia coli, GI1786657, Length=273, Percent_Identity=46.5201465201465, Blast_Score=266, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71988741, Length=288, Percent_Identity=37.8472222222222, Blast_Score=194, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17558508, Length=302, Percent_Identity=37.4172185430464, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI115532456, Length=279, Percent_Identity=35.4838709677419, Blast_Score=157, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17531889, Length=279, Percent_Identity=35.4838709677419, Blast_Score=157, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17531885, Length=279, Percent_Identity=35.4838709677419, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71982224, Length=308, Percent_Identity=33.7662337662338, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI212645202, Length=287, Percent_Identity=29.9651567944251, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6322480, Length=306, Percent_Identity=23.5294117647059, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 32235; Mature: 32235

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLERLEDNLFRGQNRDIGTKYVFGGQILAQALAAAQNTIENSRIAHSLHAYFLRTGNI
CCCHHHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QQPIIYNVERTRDGKSFSLRRVTAIQHGQVIFFCTASFQEREDGAEHQTNMPAVPPPEDI
CCCEEEEEEECCCCCCEEEEEEEEECCCCEEEEEECCCHHHHCCCHHCCCCCCCCCCCCC
APTPPLPPETLARMPPQMQTWLNLSGQFEFRRVPPNNTLDLQKHSAFQHLWLRMNAPLGD
CCCCCCCHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHEEEEECCCCCC
RIELHQILLTYASDFQLLETATSRHGINYHTPQVQMASLDHALWFHRPFRIDDWLLYTLE
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHCCCCCCCCEEEEEEC
SPTAQGARGLARGQFFTRNGVLIANTAQEGLMRMTNHTTPSKD
CCCCHHHHHHHCCEEEECCCEEEEECHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLSLERLEDNLFRGQNRDIGTKYVFGGQILAQALAAAQNTIENSRIAHSLHAYFLRTGNI
CCCHHHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QQPIIYNVERTRDGKSFSLRRVTAIQHGQVIFFCTASFQEREDGAEHQTNMPAVPPPEDI
CCCEEEEEEECCCCCCEEEEEEEEECCCCEEEEEECCCHHHHCCCHHCCCCCCCCCCCCC
APTPPLPPETLARMPPQMQTWLNLSGQFEFRRVPPNNTLDLQKHSAFQHLWLRMNAPLGD
CCCCCCCHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHEEEEECCCCCC
RIELHQILLTYASDFQLLETATSRHGINYHTPQVQMASLDHALWFHRPFRIDDWLLYTLE
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHCCCCCCCCEEEEEEC
SPTAQGARGLARGQFFTRNGVLIANTAQEGLMRMTNHTTPSKD
CCCCHHHHHHHCCEEEECCCEEEEECHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]