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The map label for this gene is panC

Identifier: 182680745

GI number: 182680745

Start: 237483

End: 238328

Strand: Direct

Name: panC

Synonym: XfasM23_0174

Alternate gene names: 182680745

Gene position: 237483-238328 (Clockwise)

Preceding gene: 182680744

Following gene: 182680746

Centisome position: 9.37

GC content: 52.13

Gene sequence:

>846_bases
GTGATTGATACCGTTACTGATCTGTCCAGGCTACGGGGGATTGTTGCTGACTGGAGGCGTCAGGGCTTGCGGGTCGCTCT
GGTGCCTACCATGGGTAATTTGCATGCTGGCCATTTTTCATTGGTTATGTTGGCTCGTCATTATGCTGATCGGGTAGTGT
CAAGTGTGTTTGTCAATCCGACGCAGTTTGGTCCCCACGAAGATTTTCAGCGTTATCCGCGAACACCCGAGGCAGACATG
CGCGGTTTGGAACATGTGGGTTGCGATGTCTTGTGGTTGCCTAGTGTGGAGACGATGTACCCGTTGGGCACTGAGCGGAC
TGTACGTCTGTTTATTCCGTGTGTGAGTGATGTGCTGGAGGGGACGTTCCGTCCTGGACACTTTGAGGGTGTTTGTACAG
TGGTGGCACGGCTGTTCAATCAGGTGCTGCCGGATGTTGCTGTGTTCGGAAAGAAGGACTATCAGCAATTGGTGGTGATC
CGGCAGATGGTGGTTGATTTAGCGTTTCCCATTGAGATTCTTGGTGGCTGTATCGTGCGTGAGTCCGATGGATTGGCGAT
GAGTTCCCGTAATCAGTATCTATCAATGCAGCAACGACCGCAGGCTGCGGAGATTCATCGTACGTTGATAGCAATGCGCG
ATGCTGTGATGTCAGGTGGTGTACACGCAGATGTCGAAGCTGAAGCGGTTCGGCGTTTGGAAGCGGCTGGGTTCCAGGTT
GATTATGCGGTTATCCGATTGCCTGATCTATGCGAGCCGATTGACGGCATTGTTATCAGTCAGGGTATTGCACTTGTTGC
TGCACGTTTAGGCAACACCCGCCTGATCGATAATCTTGAGTTCTGA

Upstream 100 bases:

>100_bases
ATTTTCTCGCTCATGGGGGATCGGTTGCTGGCGCGGTTCGCGCTTATGCGAATGCGGTTCGAGATGGTTCGTTTCCAGAT
GTCGAGCATACTTACACATC

Downstream 100 bases:

>100_bases
TTATTCGTTCCGAATTAATTGTTACCACCGGTAGATGTCTGTCATTGGCTACAATCACTTTCCCTACTTTGCTGTGTTTC
CCATGCAACTGTCCTTGCTT

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MIDTVTDLSRLRGIVADWRRQGLRVALVPTMGNLHAGHFSLVMLARHYADRVVSSVFVNPTQFGPHEDFQRYPRTPEADM
RGLEHVGCDVLWLPSVETMYPLGTERTVRLFIPCVSDVLEGTFRPGHFEGVCTVVARLFNQVLPDVAVFGKKDYQQLVVI
RQMVVDLAFPIEILGGCIVRESDGLAMSSRNQYLSMQQRPQAAEIHRTLIAMRDAVMSGGVHADVEAEAVRRLEAAGFQV
DYAVIRLPDLCEPIDGIVISQGIALVAARLGNTRLIDNLEF

Sequences:

>Translated_281_residues
MIDTVTDLSRLRGIVADWRRQGLRVALVPTMGNLHAGHFSLVMLARHYADRVVSSVFVNPTQFGPHEDFQRYPRTPEADM
RGLEHVGCDVLWLPSVETMYPLGTERTVRLFIPCVSDVLEGTFRPGHFEGVCTVVARLFNQVLPDVAVFGKKDYQQLVVI
RQMVVDLAFPIEILGGCIVRESDGLAMSSRNQYLSMQQRPQAAEIHRTLIAMRDAVMSGGVHADVEAEAVRRLEAAGFQV
DYAVIRLPDLCEPIDGIVISQGIALVAARLGNTRLIDNLEF
>Mature_281_residues
MIDTVTDLSRLRGIVADWRRQGLRVALVPTMGNLHAGHFSLVMLARHYADRVVSSVFVNPTQFGPHEDFQRYPRTPEADM
RGLEHVGCDVLWLPSVETMYPLGTERTVRLFIPCVSDVLEGTFRPGHFEGVCTVVARLFNQVLPDVAVFGKKDYQQLVVI
RQMVVDLAFPIEILGGCIVRESDGLAMSSRNQYLSMQQRPQAAEIHRTLIAMRDAVMSGGVHADVEAEAVRRLEAAGFQV
DYAVIRLPDLCEPIDGIVISQGIALVAARLGNTRLIDNLEF

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family

Homologues:

Organism=Escherichia coli, GI1786325, Length=275, Percent_Identity=46.1818181818182, Blast_Score=228, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6322046, Length=215, Percent_Identity=41.8604651162791, Blast_Score=157, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PANC_XYLF2 (B2I721)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001828905.1
- ProteinModelPortal:   B2I721
- SMR:   B2I721
- GeneID:   6204093
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0174
- HOGENOM:   HBG428839
- OMA:   RLIDNFT
- ProtClustDB:   PRK00380
- GO:   GO:0005737
- HAMAP:   MF_00158
- InterPro:   IPR003721
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR21299:SF1
- TIGRFAMs:   TIGR00018

Pfam domain/function: PF02569 Pantoate_ligase

EC number: =6.3.2.1

Molecular weight: Translated: 31268; Mature: 31268

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: ACT_SITE 38-38 BINDING 62-62 BINDING 62-62 BINDING 156-156 BINDING 179-179

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTVTDLSRLRGIVADWRRQGLRVALVPTMGNLHAGHFSLVMLARHYADRVVSSVFVNP
CCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
TQFGPHEDFQRYPRTPEADMRGLEHVGCDVLWLPSVETMYPLGTERTVRLFIPCVSDVLE
CCCCCCHHHHHCCCCCCHHHHHHHHCCCCEEECCCCHHHCCCCCCCEEEEHHHHHHHHHH
GTFRPGHFEGVCTVVARLFNQVLPDVAVFGKKDYQQLVVIRQMVVDLAFPIEILGGCIVR
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
ESDGLAMSSRNQYLSMQQRPQAAEIHRTLIAMRDAVMSGGVHADVEAEAVRRLEAAGFQV
CCCCCEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEE
DYAVIRLPDLCEPIDGIVISQGIALVAARLGNTRLIDNLEF
EHHEEECCHHCCHHCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIDTVTDLSRLRGIVADWRRQGLRVALVPTMGNLHAGHFSLVMLARHYADRVVSSVFVNP
CCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
TQFGPHEDFQRYPRTPEADMRGLEHVGCDVLWLPSVETMYPLGTERTVRLFIPCVSDVLE
CCCCCCHHHHHCCCCCCHHHHHHHHCCCCEEECCCCHHHCCCCCCCEEEEHHHHHHHHHH
GTFRPGHFEGVCTVVARLFNQVLPDVAVFGKKDYQQLVVIRQMVVDLAFPIEILGGCIVR
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
ESDGLAMSSRNQYLSMQQRPQAAEIHRTLIAMRDAVMSGGVHADVEAEAVRRLEAAGFQV
CCCCCEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEE
DYAVIRLPDLCEPIDGIVISQGIALVAARLGNTRLIDNLEF
EHHEEECCHHCCHHCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA