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The map label for this gene is cysQ [H]

Identifier: 182680711

GI number: 182680711

Start: 195290

End: 196090

Strand: Reverse

Name: cysQ [H]

Synonym: XfasM23_0140

Alternate gene names: 182680711

Gene position: 196090-195290 (Counterclockwise)

Preceding gene: 182680712

Following gene: 182680710

Centisome position: 7.73

GC content: 55.06

Gene sequence:

>801_bases
GTGATCACTATTCCCAGCGATCTTCACGAATCGGTCATCGCCATTGCTACAGATTCCGGCAGAGCGATCATGAAGATCTA
TCAGGATCATTTCAAGGTCCAGATCAAAGCAGACATGAGTCCACTGACGCAGGCCGATTTAATCTCACATCAGATCATCG
TGCATGGACTCAAGCAACTGACCCCCAGTCTGCCCGTGTTGTCGGAAGAGTCGACAGGAATCACTTGGGAGGAACGCCGT
CACTGGAAGAGCTACTGGTTGGTCGATCCACTCGACGGCACCCGCGAATTTGTGAAACGCAATGGCGAGTTTTGCATAAA
CATCGCACTGATCCATGAAGGTATCCCCGTATATGGAATGATCCTGGCGCCGGTGGAAGGGACCATCTGGCATGCAATGC
ATGGCGGGCAGGCATTCCGCCGTGATGGTCACCGTGATACCACATTGCACGTGCGGGCACCTGCTGGCACCGCGTTACAG
GTCGCAGCAAGCCGGTCGCACATTGATGTGCACACCTCGGCGTTACTGGCACAGATGAAAGAAATAACTCTAGTTTCGCA
GGGATCGGCGCTGAAGTTCTGTCGCCTTGCTGAAGGCACACTCGACGTGTACCCGCGTCTAGGCGCTACCTATGAGTGGG
ATACTGCCGCAGGCCAGTGCTTACTGCTTGCTGCGGGCGGTACGCTACTGAACATTGAGACTGGAAAACCGTTCCGCTAC
AACAAACGCGAGACACTGCTTAACGGCGGTTTTATCGCACTGGGCGACGCCACGCTGCCTTGGCGCGATTGGTTGCCCTG
A

Upstream 100 bases:

>100_bases
AGCTTTCAAAGTTGCACGATTTGATGCTGCGTGAGGATTTCTCCGAAGGGCGCTCCCTGGCAGCATTGTTCATTGTCCGT
GAATGGCTGGAACATCAGCA

Downstream 100 bases:

>100_bases
CTCCATCTTATTCCCCATTCTGGCGCTTTCCGTATGTCCGATCTTCCCGACGCATCACCCCACATTGAAACGTTGCTATC
CATCATGGCGCGCCTGCGCG

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MITIPSDLHESVIAIATDSGRAIMKIYQDHFKVQIKADMSPLTQADLISHQIIVHGLKQLTPSLPVLSEESTGITWEERR
HWKSYWLVDPLDGTREFVKRNGEFCINIALIHEGIPVYGMILAPVEGTIWHAMHGGQAFRRDGHRDTTLHVRAPAGTALQ
VAASRSHIDVHTSALLAQMKEITLVSQGSALKFCRLAEGTLDVYPRLGATYEWDTAAGQCLLLAAGGTLLNIETGKPFRY
NKRETLLNGGFIALGDATLPWRDWLP

Sequences:

>Translated_266_residues
MITIPSDLHESVIAIATDSGRAIMKIYQDHFKVQIKADMSPLTQADLISHQIIVHGLKQLTPSLPVLSEESTGITWEERR
HWKSYWLVDPLDGTREFVKRNGEFCINIALIHEGIPVYGMILAPVEGTIWHAMHGGQAFRRDGHRDTTLHVRAPAGTALQ
VAASRSHIDVHTSALLAQMKEITLVSQGSALKFCRLAEGTLDVYPRLGATYEWDTAAGQCLLLAAGGTLLNIETGKPFRY
NKRETLLNGGFIALGDATLPWRDWLP
>Mature_266_residues
MITIPSDLHESVIAIATDSGRAIMKIYQDHFKVQIKADMSPLTQADLISHQIIVHGLKQLTPSLPVLSEESTGITWEERR
HWKSYWLVDPLDGTREFVKRNGEFCINIALIHEGIPVYGMILAPVEGTIWHAMHGGQAFRRDGHRDTTLHVRAPAGTALQ
VAASRSHIDVHTSALLAQMKEITLVSQGSALKFCRLAEGTLDVYPRLGATYEWDTAAGQCLLLAAGGTLLNIETGKPFRY
NKRETLLNGGFIALGDATLPWRDWLP

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=242, Percent_Identity=23.1404958677686, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI221625487, Length=242, Percent_Identity=23.1404958677686, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1790659, Length=244, Percent_Identity=46.3114754098361, Blast_Score=190, Evalue=7e-50,
Organism=Escherichia coli, GI1788882, Length=230, Percent_Identity=24.3478260869565, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71995897, Length=246, Percent_Identity=29.6747967479675, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71995905, Length=246, Percent_Identity=29.6747967479675, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29467; Mature: 29467

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS ; PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIPSDLHESVIAIATDSGRAIMKIYQDHFKVQIKADMSPLTQADLISHQIIVHGLKQL
CCCCCCHHCCCEEEEEECCCHHHHHEEHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
TPSLPVLSEESTGITWEERRHWKSYWLVDPLDGTREFVKRNGEFCINIALIHEGIPVYGM
CCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCHHHHHHHCCCCEEEEEEEEECCCCEEEE
ILAPVEGTIWHAMHGGQAFRRDGHRDTTLHVRAPAGTALQVAASRSHIDVHTSALLAQMK
EEECCCCEEEEEECCCHHHHCCCCCCCEEEEECCCCCEEEEECCCCCEEHHHHHHHHHHH
EITLVSQGSALKFCRLAEGTLDVYPRLGATYEWDTAAGQCLLLAAGGTLLNIETGKPFRY
HEEEEECCCCEEEEEECCCCEEECCCCCCEEEECCCCCCEEEEEECCEEEEEECCCCCCC
NKRETLLNGGFIALGDATLPWRDWLP
CCHHHEECCCEEEECCCCCCHHCCCC
>Mature Secondary Structure
MITIPSDLHESVIAIATDSGRAIMKIYQDHFKVQIKADMSPLTQADLISHQIIVHGLKQL
CCCCCCHHCCCEEEEEECCCHHHHHEEHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
TPSLPVLSEESTGITWEERRHWKSYWLVDPLDGTREFVKRNGEFCINIALIHEGIPVYGM
CCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCHHHHHHHCCCCEEEEEEEEECCCCEEEE
ILAPVEGTIWHAMHGGQAFRRDGHRDTTLHVRAPAGTALQVAASRSHIDVHTSALLAQMK
EEECCCCEEEEEECCCHHHHCCCCCCCEEEEECCCCCEEEEECCCCCEEHHHHHHHHHHH
EITLVSQGSALKFCRLAEGTLDVYPRLGATYEWDTAAGQCLLLAAGGTLLNIETGKPFRY
HEEEEECCCCEEEEEECCCCEEECCCCCCEEEECCCCCCEEEEEECCEEEEEECCCCCCC
NKRETLLNGGFIALGDATLPWRDWLP
CCHHHEECCCEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]