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The map label for this gene is argS

Identifier: 182680680

GI number: 182680680

Start: 147632

End: 149320

Strand: Reverse

Name: argS

Synonym: XfasM23_0109

Alternate gene names: 182680680

Gene position: 149320-147632 (Counterclockwise)

Preceding gene: 182680681

Following gene: 182680679

Centisome position: 5.89

GC content: 53.88

Gene sequence:

>1689_bases
GTGAAAGCCCCAGTCCGCGCCCTGATTTGCCAAGGCATCGAAGCATTGCGTAGCAATGGCACCTTACCTACTAATACTCT
GCCTCCAGATTTCGTAGTGGAACGTCCAAAGACGCGCAAACATGGCGACTTTGCGACCAACGTAGCAATGCTGCTCAGCA
AAGCGACTGGCAGCAATCCCCGCCTACTGGCACAGACTCTGGTTGCAGCACTGCCAACCAGCGCCGACATTGCACGGATA
GAAATCGCCGGCCCAGGCTTCATCAACTTCCACCTGCATCCAGTCGCGTACCAGCGTGAAACAATCAACGTGCTTAAACA
GGATAACGACTACGGTCGGAACCTGTCCGGCCAAAGTCGCACCGTCGGAGTGGAATACGTCTCAGCCAATCCGACAGGTC
CACTGCATGTCGGTCACGGACGCGCCGCAGCCATCGGTGACTGCCTTGCGCGTTTACTGGAAGCCAATGGCTGGAACGTC
AAACGCGAGTTCTATTACAACGACGCCGGCGTACAAATCGAGAATCTTGTCCGCTCAGTGCAGGCACGCGCACGCGGACT
GAAGCCTGGAGACGCCCTTTGGCCAACAGATGCCTACAACGGCGAGTACATCGCCGACATTGCCAAAGCCTATTTGGCTG
GCGACAGCATCAACATGGTAGATACCATCATCACCAGCACCAAAAACGTCGACGACACAGCAGCAATCCACCACTTCGCC
GTCAACTACCTACGTAACGAACAAAACCACGACCTGGCCGCATTTAACGTCGATTTCGATATCTACTTTCTGGAAAGCTC
GCTTTACAAAGATGGCAAAGTCGAAGAAACAGTCCAGAAACTGATCAATTCCGGCCACACCTATGAGGAGGGCGGCGCAC
TGTGGCTGAAGTCAACCCATTTCGGTGACGACAAAGATCGGGTCATGCGCAAATCCGACGGTAGCTACACCTACTTCGTA
CCAGACATCGCATACCATTTAAGCAAATGGCAACGTGGCTACGAACGCGCAATCACCGAACTAGGAGCCGACCATCACGG
TTCACTGGCACGCGTCCACGCTGGACTACAAGCATTAGAAATAGGCATCCCGCCCGGCTGGCCAGAATATGTGCTGCACC
AAATGGTCACTGTCATGCGTGGTGGCGAAGAAGTGAAGCTCTCCAAACGTTCTGGAGGCTACGTCACGCTACGTGACCTG
ATTGAGGAGACCAGCACCGATGCAACACGCTGGTTTCTGATCGCACGCAAACCCGATTCACAACTTACCTTCGACATCGA
CCTGGCCCGTCAAAAGAGCAACGACAACCCTGTATTCTACGTACAGTACGCATACGCCCGCGTCTGTAGCCTGATGCACC
AAGCCCATGAAAAGAACTTAAATTACGATCAAACCAGCGGCATGGCGTCCCTTGATCAACTTTCAGACAACACCTCACTG
TGTCTGATGATCGAGATATCACGCTATCCTGAAATCGTGCAAATCGCCTGCGAACTGCTGGAACCTCACCTGATCGCACA
ATACCTGCGTGAATTAGCGCATGCATTCCATACCTGGTATCACAACACACCCGTACTGGTAGAGAACGCAGTAGAACGCA
ACGCAAAGCTGACACTGGCCTGCGCAACCAGGCAAGTCCTCGCCAACGGCCTGAACCTACTCGGCGTCGGCACCCCGGAA
AAGATGTGA

Upstream 100 bases:

>100_bases
GGGAGGGCTGCCAAGCAGCCTACAAACTGAATGCTAACGCGCTCCTCATACAAACGGTCAGATAAAATTACGCTATCTAT
CGCCACACACCCACACCCAC

Downstream 100 bases:

>100_bases
ATCAAACACACCGCTATGAAGAAGTAATTGGAGAAGTTGATGGCAACACCGCGCGCTAGAAACCAAGCACGGCGCAACAC
TAATAATGCCCCTCCAGGAT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MKAPVRALICQGIEALRSNGTLPTNTLPPDFVVERPKTRKHGDFATNVAMLLSKATGSNPRLLAQTLVAALPTSADIARI
EIAGPGFINFHLHPVAYQRETINVLKQDNDYGRNLSGQSRTVGVEYVSANPTGPLHVGHGRAAAIGDCLARLLEANGWNV
KREFYYNDAGVQIENLVRSVQARARGLKPGDALWPTDAYNGEYIADIAKAYLAGDSINMVDTIITSTKNVDDTAAIHHFA
VNYLRNEQNHDLAAFNVDFDIYFLESSLYKDGKVEETVQKLINSGHTYEEGGALWLKSTHFGDDKDRVMRKSDGSYTYFV
PDIAYHLSKWQRGYERAITELGADHHGSLARVHAGLQALEIGIPPGWPEYVLHQMVTVMRGGEEVKLSKRSGGYVTLRDL
IEETSTDATRWFLIARKPDSQLTFDIDLARQKSNDNPVFYVQYAYARVCSLMHQAHEKNLNYDQTSGMASLDQLSDNTSL
CLMIEISRYPEIVQIACELLEPHLIAQYLRELAHAFHTWYHNTPVLVENAVERNAKLTLACATRQVLANGLNLLGVGTPE
KM

Sequences:

>Translated_562_residues
MKAPVRALICQGIEALRSNGTLPTNTLPPDFVVERPKTRKHGDFATNVAMLLSKATGSNPRLLAQTLVAALPTSADIARI
EIAGPGFINFHLHPVAYQRETINVLKQDNDYGRNLSGQSRTVGVEYVSANPTGPLHVGHGRAAAIGDCLARLLEANGWNV
KREFYYNDAGVQIENLVRSVQARARGLKPGDALWPTDAYNGEYIADIAKAYLAGDSINMVDTIITSTKNVDDTAAIHHFA
VNYLRNEQNHDLAAFNVDFDIYFLESSLYKDGKVEETVQKLINSGHTYEEGGALWLKSTHFGDDKDRVMRKSDGSYTYFV
PDIAYHLSKWQRGYERAITELGADHHGSLARVHAGLQALEIGIPPGWPEYVLHQMVTVMRGGEEVKLSKRSGGYVTLRDL
IEETSTDATRWFLIARKPDSQLTFDIDLARQKSNDNPVFYVQYAYARVCSLMHQAHEKNLNYDQTSGMASLDQLSDNTSL
CLMIEISRYPEIVQIACELLEPHLIAQYLRELAHAFHTWYHNTPVLVENAVERNAKLTLACATRQVLANGLNLLGVGTPE
KM
>Mature_562_residues
MKAPVRALICQGIEALRSNGTLPTNTLPPDFVVERPKTRKHGDFATNVAMLLSKATGSNPRLLAQTLVAALPTSADIARI
EIAGPGFINFHLHPVAYQRETINVLKQDNDYGRNLSGQSRTVGVEYVSANPTGPLHVGHGRAAAIGDCLARLLEANGWNV
KREFYYNDAGVQIENLVRSVQARARGLKPGDALWPTDAYNGEYIADIAKAYLAGDSINMVDTIITSTKNVDDTAAIHHFA
VNYLRNEQNHDLAAFNVDFDIYFLESSLYKDGKVEETVQKLINSGHTYEEGGALWLKSTHFGDDKDRVMRKSDGSYTYFV
PDIAYHLSKWQRGYERAITELGADHHGSLARVHAGLQALEIGIPPGWPEYVLHQMVTVMRGGEEVKLSKRSGGYVTLRDL
IEETSTDATRWFLIARKPDSQLTFDIDLARQKSNDNPVFYVQYAYARVCSLMHQAHEKNLNYDQTSGMASLDQLSDNTSL
CLMIEISRYPEIVQIACELLEPHLIAQYLRELAHAFHTWYHNTPVLVENAVERNAKLTLACATRQVLANGLNLLGVGTPE
KM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=606, Percent_Identity=25.9075907590759, Blast_Score=116, Evalue=4e-26,
Organism=Escherichia coli, GI1788184, Length=614, Percent_Identity=26.2214983713355, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71985061, Length=601, Percent_Identity=24.459234608985, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71985068, Length=564, Percent_Identity=24.645390070922, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320548, Length=574, Percent_Identity=24.5644599303136, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6321883, Length=561, Percent_Identity=24.0641711229947, Blast_Score=112, Evalue=2e-25,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_XYLF2 (B2I6M4)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001828840.1
- ProteinModelPortal:   B2I6M4
- SMR:   B2I6M4
- GeneID:   6203394
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0109
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 62537; Mature: 62537

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAPVRALICQGIEALRSNGTLPTNTLPPDFVVERPKTRKHGDFATNVAMLLSKATGSNP
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCC
RLLAQTLVAALPTSADIARIEIAGPGFINFHLHPVAYQRETINVLKQDNDYGRNLSGQSR
HHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCE
TVGVEYVSANPTGPLHVGHGRAAAIGDCLARLLEANGWNVKREFYYNDAGVQIENLVRSV
EEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHH
QARARGLKPGDALWPTDAYNGEYIADIAKAYLAGDSINMVDTIITSTKNVDDTAAIHHFA
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHH
VNYLRNEQNHDLAAFNVDFDIYFLESSLYKDGKVEETVQKLINSGHTYEEGGALWLKSTH
HHHHHCCCCCCEEEEEEEEEEEEEECHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECC
FGDDKDRVMRKSDGSYTYFVPDIAYHLSKWQRGYERAITELGADHHGSLARVHAGLQALE
CCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCEEE
IGIPPGWPEYVLHQMVTVMRGGEEVKLSKRSGGYVTLRDLIEETSTDATRWFLIARKPDS
ECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEHHHHHHHCCCCCEEEEEEEECCCC
QLTFDIDLARQKSNDNPVFYVQYAYARVCSLMHQAHEKNLNYDQTSGMASLDQLSDNTSL
CEEEEEEEHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCE
CLMIEISRYPEIVQIACELLEPHLIAQYLRELAHAFHTWYHNTPVLVENAVERNAKLTLA
EEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCEEEEE
CATRQVLANGLNLLGVGTPEKM
HHHHHHHHCCCCEEECCCCCCC
>Mature Secondary Structure
MKAPVRALICQGIEALRSNGTLPTNTLPPDFVVERPKTRKHGDFATNVAMLLSKATGSNP
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHCCCCCC
RLLAQTLVAALPTSADIARIEIAGPGFINFHLHPVAYQRETINVLKQDNDYGRNLSGQSR
HHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCE
TVGVEYVSANPTGPLHVGHGRAAAIGDCLARLLEANGWNVKREFYYNDAGVQIENLVRSV
EEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHH
QARARGLKPGDALWPTDAYNGEYIADIAKAYLAGDSINMVDTIITSTKNVDDTAAIHHFA
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHH
VNYLRNEQNHDLAAFNVDFDIYFLESSLYKDGKVEETVQKLINSGHTYEEGGALWLKSTH
HHHHHCCCCCCEEEEEEEEEEEEEECHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECC
FGDDKDRVMRKSDGSYTYFVPDIAYHLSKWQRGYERAITELGADHHGSLARVHAGLQALE
CCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCEEE
IGIPPGWPEYVLHQMVTVMRGGEEVKLSKRSGGYVTLRDLIEETSTDATRWFLIARKPDS
ECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEHHHHHHHCCCCCEEEEEEEECCCC
QLTFDIDLARQKSNDNPVFYVQYAYARVCSLMHQAHEKNLNYDQTSGMASLDQLSDNTSL
CEEEEEEEHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCE
CLMIEISRYPEIVQIACELLEPHLIAQYLRELAHAFHTWYHNTPVLVENAVERNAKLTLA
EEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCEEEEE
CATRQVLANGLNLLGVGTPEKM
HHHHHHHHCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA