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The map label for this gene is holC [H]

Identifier: 182680667

GI number: 182680667

Start: 133821

End: 134246

Strand: Reverse

Name: holC [H]

Synonym: XfasM23_0096

Alternate gene names: 182680667

Gene position: 134246-133821 (Counterclockwise)

Preceding gene: 182680668

Following gene: 182680666

Centisome position: 5.29

GC content: 60.56

Gene sequence:

>426_bases
ATGGCACGCGCCGACTTCTATTTGATTGCCAAACCGCGCTTTCTTGAGAAACCGCTGCAATTAGTCTGCGAATTAGTCCG
CAAAGCCTACGACACCCATCAGCCCACACTGATTCTGGCCCGCGACCAGGCCCAGGCCGAAGCACTGGATGACCTACTGT
GGGCGTTCGACCCGGACGCCTACATCCCCCACCAAATCGCTGGCAGCGACGAAGACGACGACATCACCCCCGTATTGATT
GCCACCCCGGACAGCGACACCCCATCGCGCCCGCTGGTCATCAACCTACGCGACGCCCCTTGGGATGGCCCCTGCGAACG
CGTGTTGGAGGTGGTTCCCGCTGATCCTGCGGCACGCGAGCCACTGCGTGAACGCTGGAAACACTACAAGGCACGCGGCC
TGCACATGAACAAACACGACATGTGA

Upstream 100 bases:

>100_bases
CCCTTGGCGCTTTAATTGAATTAAGACGACAACTGAAAATCAAGTTGGACCCTCAGAAAGCCACCGAACGGCTACGTGCC
ATGCTCGAGAAACTGGATTA

Downstream 100 bases:

>100_bases
CCACGCTGCCATCCCCTCATTAAATAAGACCATCCATCCCTTTAAGACAAAAAATCCCAACAATGCGCTTACTCATTGCT
CTCCTGTTACCGTGTCTACT

Product: DNA polymerase III subunit chi

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MARADFYLIAKPRFLEKPLQLVCELVRKAYDTHQPTLILARDQAQAEALDDLLWAFDPDAYIPHQIAGSDEDDDITPVLI
ATPDSDTPSRPLVINLRDAPWDGPCERVLEVVPADPAAREPLRERWKHYKARGLHMNKHDM

Sequences:

>Translated_141_residues
MARADFYLIAKPRFLEKPLQLVCELVRKAYDTHQPTLILARDQAQAEALDDLLWAFDPDAYIPHQIAGSDEDDDITPVLI
ATPDSDTPSRPLVINLRDAPWDGPCERVLEVVPADPAAREPLRERWKHYKARGLHMNKHDM
>Mature_140_residues
ARADFYLIAKPRFLEKPLQLVCELVRKAYDTHQPTLILARDQAQAEALDDLLWAFDPDAYIPHQIAGSDEDDDITPVLIA
TPDSDTPSRPLVINLRDAPWDGPCERVLEVVPADPAAREPLRERWKHYKARGLHMNKHDM

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2927

COG function: function code L; DNA polymerase III, chi subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790709, Length=143, Percent_Identity=32.1678321678322, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007459 [H]

Pfam domain/function: PF04364 DNA_pol3_chi [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 16104; Mature: 15973

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARADFYLIAKPRFLEKPLQLVCELVRKAYDTHQPTLILARDQAQAEALDDLLWAFDPDA
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCC
YIPHQIAGSDEDDDITPVLIATPDSDTPSRPLVINLRDAPWDGPCERVLEVVPADPAARE
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCH
PLRERWKHYKARGLHMNKHDM
HHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ARADFYLIAKPRFLEKPLQLVCELVRKAYDTHQPTLILARDQAQAEALDDLLWAFDPDA
CCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCC
YIPHQIAGSDEDDDITPVLIATPDSDTPSRPLVINLRDAPWDGPCERVLEVVPADPAARE
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCH
PLRERWKHYKARGLHMNKHDM
HHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9864319; 10984043 [H]