BacMap

Definition	Xylella fastidiosa M23 chromosome, complete genome.
Accession	NC_010577
Length	2,535,690

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The map label for this gene is ftsH [H]

Identifier: 182680633

GI number: 182680633

Start: 90476

End: 92413

Strand: Reverse

Name: ftsH [H]

Synonym: XfasM23_0062

Alternate gene names: 182680633

Gene position: 92413-90476 (Counterclockwise)

Preceding gene: 182680634

Following gene: 182680631

Centisome position: 3.64

GC content: 51.14

Gene sequence:

>1938_bases
ATGAGGATGAACGACTTAACCAAAAATGTGTTGCTGTGGGTGGTCGTCGCCGTCGTGCTGATGGTGGTATTTCAAAGTTT
CTCGCCACGTATTGGTGGAGTGATAGGCAACGAACCAATCACCTATACACAATTTCTGAATGAAGTGGATAGCGGTCGGA
TCAAGTCGGTGAACTACACCGACGAGAGTGGCCTGACTGTCAACGCGATTCGCTTCAAACGCACCGACGGTAGCGAGGGT
TTGGTCTACGGACCACGCGACGACAAATTGGTCGACGTGTTATACAGCAAGAACATTGAGATGACCCGGCAAAAGCCTTC
CACCGGCCCAGGCTTTTGGTCTCTAGTATTGAATTTTCTACCAGTCATCCTAATCATTGGATTCTGGGTTTTCATCATGC
GCCAGATGCAAGGTGGTGGGGCTAAAGGTGCGATGTCGTTTGGGAAATCCCGTGCAAAATTGCAAGGCGATGACCAGATC
AAAATCACTTTTGCTGACGTCGCCGGTTGCGACGAAGCCAAAGAGGAAGTTGGTGAGCTGGTCGATTTTTTGCGTGACCC
CACTAAATTCACCAAGCTTGGCGGCAAGATTCCACGTGGAGTCTTGATGGTGGGTCCTCCAGGCACCGGCAAGACGTTAT
TAGCCAAAGCAATCGCTGGGGAAGCAAAAGTGCCTTTCTTTTCGATTTCTGGATCTGACTTCGTCGAAATGTTTGTTGGG
GTCGGTGCTAGCCGTGTTCGTGACATGTTTGAGCAAGCCAAAAAGCATGCCCCATGCATTATTTTCATCGACGAAATCGA
CGCGGTAGGCCGTCATCGAGGTGCAGGCTTAGGCGGAGGCCATGACGAACGCGAACAAACTTTAAACCAGCTCCTGGTCG
AAATGGACGGCTTTGAAGGCGGTGAAGGCGTGATTGTGATCGCCGCGACGAATCGCCCTGACGTGCTCGACCCTGCGCTG
CTGCGCCCAGGTCGCTTCGACCGTCAAGTTGTGGTTGCTCTACCAGACGTTAAAGGCCGTGAGCAGATCCTAGGTGTTCA
TATGCGTAAGTTACTGTTAGCCAATGACGTCGAGCCGCTCGTGATTGCACGTGGAACCCCTGGTTTTTCTGGAGCTGACT
TAGCCAATCTGTGCAATGAAGCAGCGTTATTCGCCGCGCGTAGCAACGAAAAGGAAGTCAGAATGAACCATTTCGACGCT
GCCCGCGACAAAATACTCATGGGCACTGAACGTCGCTCAATGGCAATGAGTGAGGAAGAAAAAACCCTTACTGCTTACCA
CGAAGCTGGTCATGCCATCGTTGGCCGCTTAGTACCTGAGCATGACCCTGTGTACAAAGTCACGATTATCCCCCGTGGCC
GTGCTTTGGGCGTCACCATGTATCTTCCTGAAGGTGACAAATACTCAATCAATAAAGTGGCTATTCAGTCCCAACTATGC
TCCTTATATGGTGGCCGTGTTGCCGAAGAATTAATCTTCGGTGAGGATAAAGTCACAACTGGCGCTTCTAATGATATTGA
ACGTGTGACCAAGATGGCACGCAATATGGTCACCAAGTGGGGACTCTCGGATGAACTGGGTCCGGTTGCTTATGGCGAGG
AAGAGGATGAAGTTTTTCTTGGCCGTTCTGTGACTCAACATAAAAATGTCTCAGATGAAACGGCCCGCAAAATTGATGAG
GTAGTGCGCTCTATCTTGGACAAAGCGTACGCTCGTACCAAGCGGATTTTGGCAGATAACTTAGATAAGCTCCACGCGAT
GTCCCAGCTGCTGCTGCAGTACGAAACCATCGACGCACCTCAGATTGATGCCATTATGGAGGGTCGTGCCCCCCCCCCGC
CGGTTGGCTGGGGTAAACCTTCTGACAATGGTAGCGACGACGACATGAGTAAGCCCCGCCCATTAACTACCATCGTTGTT
CCAGCTGAGCAGGTTTGA

Upstream 100 bases:

>100_bases
GTTTATATCCTTGGTGACGGCAAGCTCACTCAGAATGAAGTAAGCTGCTCGTGAGTGGTCGCATTCGAATATTGAGAGTA
AATGAGAGGCACTGGAACCA

Downstream 100 bases:

>100_bases
TCTAAACAGTAATCACTGCACCGTCATATACACCGGCCCTAGAGTCATCCTGGGCCGGTTGTGTCTTTGAAACGCAATAA
ACTGTCACACCACAGATAGC

Product: ATP-dependent metalloprotease FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MRMNDLTKNVLLWVVVAVVLMVVFQSFSPRIGGVIGNEPITYTQFLNEVDSGRIKSVNYTDESGLTVNAIRFKRTDGSEG
LVYGPRDDKLVDVLYSKNIEMTRQKPSTGPGFWSLVLNFLPVILIIGFWVFIMRQMQGGGAKGAMSFGKSRAKLQGDDQI
KITFADVAGCDEAKEEVGELVDFLRDPTKFTKLGGKIPRGVLMVGPPGTGKTLLAKAIAGEAKVPFFSISGSDFVEMFVG
VGASRVRDMFEQAKKHAPCIIFIDEIDAVGRHRGAGLGGGHDEREQTLNQLLVEMDGFEGGEGVIVIAATNRPDVLDPAL
LRPGRFDRQVVVALPDVKGREQILGVHMRKLLLANDVEPLVIARGTPGFSGADLANLCNEAALFAARSNEKEVRMNHFDA
ARDKILMGTERRSMAMSEEEKTLTAYHEAGHAIVGRLVPEHDPVYKVTIIPRGRALGVTMYLPEGDKYSINKVAIQSQLC
SLYGGRVAEELIFGEDKVTTGASNDIERVTKMARNMVTKWGLSDELGPVAYGEEEDEVFLGRSVTQHKNVSDETARKIDE
VVRSILDKAYARTKRILADNLDKLHAMSQLLLQYETIDAPQIDAIMEGRAPPPPVGWGKPSDNGSDDDMSKPRPLTTIVV
PAEQV

Sequences:

>Translated_645_residues
MRMNDLTKNVLLWVVVAVVLMVVFQSFSPRIGGVIGNEPITYTQFLNEVDSGRIKSVNYTDESGLTVNAIRFKRTDGSEG
LVYGPRDDKLVDVLYSKNIEMTRQKPSTGPGFWSLVLNFLPVILIIGFWVFIMRQMQGGGAKGAMSFGKSRAKLQGDDQI
KITFADVAGCDEAKEEVGELVDFLRDPTKFTKLGGKIPRGVLMVGPPGTGKTLLAKAIAGEAKVPFFSISGSDFVEMFVG
VGASRVRDMFEQAKKHAPCIIFIDEIDAVGRHRGAGLGGGHDEREQTLNQLLVEMDGFEGGEGVIVIAATNRPDVLDPAL
LRPGRFDRQVVVALPDVKGREQILGVHMRKLLLANDVEPLVIARGTPGFSGADLANLCNEAALFAARSNEKEVRMNHFDA
ARDKILMGTERRSMAMSEEEKTLTAYHEAGHAIVGRLVPEHDPVYKVTIIPRGRALGVTMYLPEGDKYSINKVAIQSQLC
SLYGGRVAEELIFGEDKVTTGASNDIERVTKMARNMVTKWGLSDELGPVAYGEEEDEVFLGRSVTQHKNVSDETARKIDE
VVRSILDKAYARTKRILADNLDKLHAMSQLLLQYETIDAPQIDAIMEGRAPPPPVGWGKPSDNGSDDDMSKPRPLTTIVV
PAEQV
>Mature_645_residues
MRMNDLTKNVLLWVVVAVVLMVVFQSFSPRIGGVIGNEPITYTQFLNEVDSGRIKSVNYTDESGLTVNAIRFKRTDGSEG
LVYGPRDDKLVDVLYSKNIEMTRQKPSTGPGFWSLVLNFLPVILIIGFWVFIMRQMQGGGAKGAMSFGKSRAKLQGDDQI
KITFADVAGCDEAKEEVGELVDFLRDPTKFTKLGGKIPRGVLMVGPPGTGKTLLAKAIAGEAKVPFFSISGSDFVEMFVG
VGASRVRDMFEQAKKHAPCIIFIDEIDAVGRHRGAGLGGGHDEREQTLNQLLVEMDGFEGGEGVIVIAATNRPDVLDPAL
LRPGRFDRQVVVALPDVKGREQILGVHMRKLLLANDVEPLVIARGTPGFSGADLANLCNEAALFAARSNEKEVRMNHFDA
ARDKILMGTERRSMAMSEEEKTLTAYHEAGHAIVGRLVPEHDPVYKVTIIPRGRALGVTMYLPEGDKYSINKVAIQSQLC
SLYGGRVAEELIFGEDKVTTGASNDIERVTKMARNMVTKWGLSDELGPVAYGEEEDEVFLGRSVTQHKNVSDETARKIDE
VVRSILDKAYARTKRILADNLDKLHAMSQLLLQYETIDAPQIDAIMEGRAPPPPVGWGKPSDNGSDDDMSKPRPLTTIVV
PAEQV

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI300192933, Length=495, Percent_Identity=48.0808080808081, Blast_Score=465, Evalue=1e-131,
Organism=Homo sapiens, GI21327685, Length=448, Percent_Identity=50.2232142857143, Blast_Score=448, Evalue=1e-126,
Organism=Homo sapiens, GI7657689, Length=448, Percent_Identity=50.2232142857143, Blast_Score=447, Evalue=1e-125,
Organism=Homo sapiens, GI4507173, Length=498, Percent_Identity=43.1726907630522, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI4506209, Length=254, Percent_Identity=40.9448818897638, Blast_Score=213, Evalue=5e-55,
Organism=Homo sapiens, GI24497435, Length=257, Percent_Identity=40.8560311284047, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI24430151, Length=247, Percent_Identity=41.7004048582996, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI6005942, Length=226, Percent_Identity=44.2477876106195, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI21361144, Length=251, Percent_Identity=42.2310756972112, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI195539395, Length=253, Percent_Identity=39.5256916996047, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI89064750, Length=259, Percent_Identity=40.5405405405405, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI5729991, Length=259, Percent_Identity=40.5405405405405, Blast_Score=190, Evalue=4e-48,
Organism=Homo sapiens, GI24430155, Length=259, Percent_Identity=40.5405405405405, Blast_Score=190, Evalue=4e-48,
Organism=Homo sapiens, GI45643123, Length=227, Percent_Identity=45.374449339207, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI45643125, Length=227, Percent_Identity=45.374449339207, Blast_Score=186, Evalue=8e-47,
Organism=Homo sapiens, GI157671927, Length=250, Percent_Identity=38.4, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI40806173, Length=180, Percent_Identity=50.5555555555556, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI4505725, Length=210, Percent_Identity=43.3333333333333, Blast_Score=169, Evalue=8e-42,
Organism=Homo sapiens, GI5901990, Length=233, Percent_Identity=41.2017167381974, Blast_Score=166, Evalue=7e-41,
Organism=Homo sapiens, GI229577436, Length=280, Percent_Identity=36.0714285714286, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI24497618, Length=263, Percent_Identity=38.4030418250951, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI226371754, Length=234, Percent_Identity=40.1709401709402, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI153792536, Length=239, Percent_Identity=39.7489539748954, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI194018488, Length=295, Percent_Identity=37.9661016949153, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI14149767, Length=233, Percent_Identity=39.0557939914163, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI62177112, Length=233, Percent_Identity=39.0557939914163, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI31742536, Length=233, Percent_Identity=37.7682403433476, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI112789543, Length=233, Percent_Identity=37.7682403433476, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI11875211, Length=290, Percent_Identity=37.2413793103448, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI40806170, Length=290, Percent_Identity=37.2413793103448, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI7019569, Length=240, Percent_Identity=38.3333333333333, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI156564401, Length=214, Percent_Identity=39.7196261682243, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI17865802, Length=270, Percent_Identity=36.2962962962963, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI310125282, Length=214, Percent_Identity=39.2523364485981, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI310125280, Length=214, Percent_Identity=39.2523364485981, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI31377644, Length=237, Percent_Identity=35.8649789029536, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI64084766, Length=281, Percent_Identity=30.2491103202847, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI116292174, Length=255, Percent_Identity=30.5882352941176, Blast_Score=87, Evalue=6e-17,
Organism=Escherichia coli, GI1789568, Length=634, Percent_Identity=64.5110410094637, Blast_Score=838, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71994521, Length=542, Percent_Identity=44.6494464944649, Blast_Score=431, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17554264, Length=492, Percent_Identity=46.7479674796748, Blast_Score=431, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI115534323, Length=485, Percent_Identity=45.360824742268, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17554786, Length=257, Percent_Identity=42.8015564202335, Blast_Score=221, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI25144278, Length=257, Percent_Identity=42.8015564202335, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI25144281, Length=257, Percent_Identity=42.8015564202335, Blast_Score=216, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17563248, Length=261, Percent_Identity=40.9961685823755, Blast_Score=212, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI17532375, Length=234, Percent_Identity=44.017094017094, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI71987364, Length=254, Percent_Identity=40.9448818897638, Blast_Score=201, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI17531535, Length=236, Percent_Identity=45.3389830508475, Blast_Score=201, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI71987372, Length=254, Percent_Identity=40.9448818897638, Blast_Score=201, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI17508701, Length=251, Percent_Identity=42.2310756972112, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17563250, Length=247, Percent_Identity=40.8906882591093, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17505546, Length=248, Percent_Identity=40.7258064516129, Blast_Score=188, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17508053, Length=253, Percent_Identity=40.3162055335968, Blast_Score=185, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17554784, Length=254, Percent_Identity=40.1574803149606, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17537217, Length=220, Percent_Identity=42.2727272727273, Blast_Score=163, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI193206114, Length=245, Percent_Identity=40.4081632653061, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI133931034, Length=245, Percent_Identity=40.4081632653061, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI193206116, Length=245, Percent_Identity=40.4081632653061, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI25153574, Length=238, Percent_Identity=38.655462184874, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=47.8787878787879, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=47.8787878787879, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI193209502, Length=229, Percent_Identity=38.8646288209607, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI25146157, Length=278, Percent_Identity=35.6115107913669, Blast_Score=145, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17562804, Length=232, Percent_Identity=37.9310344827586, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI133901658, Length=212, Percent_Identity=40.0943396226415, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI133901662, Length=212, Percent_Identity=40.0943396226415, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI86561515, Length=242, Percent_Identity=33.4710743801653, Blast_Score=132, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17541226, Length=238, Percent_Identity=36.1344537815126, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17541224, Length=238, Percent_Identity=36.1344537815126, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17560432, Length=229, Percent_Identity=37.9912663755458, Blast_Score=128, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17508421, Length=260, Percent_Identity=34.6153846153846, Blast_Score=126, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI32563584, Length=241, Percent_Identity=35.6846473029046, Blast_Score=125, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71990294, Length=219, Percent_Identity=31.9634703196347, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320854, Length=505, Percent_Identity=50.0990099009901, Blast_Score=478, Evalue=1e-135,
Organism=Saccharomyces cerevisiae, GI6323736, Length=513, Percent_Identity=47.953216374269, Blast_Score=466, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6325281, Length=450, Percent_Identity=50.2222222222222, Blast_Score=459, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6322704, Length=258, Percent_Identity=41.0852713178295, Blast_Score=212, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6320077, Length=248, Percent_Identity=43.1451612903226, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6321390, Length=257, Percent_Identity=39.2996108949416, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6324691, Length=251, Percent_Identity=42.6294820717131, Blast_Score=200, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6324833, Length=237, Percent_Identity=42.1940928270042, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6320197, Length=245, Percent_Identity=38.7755102040816, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324000, Length=246, Percent_Identity=43.0894308943089, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6320602, Length=232, Percent_Identity=43.9655172413793, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6321709, Length=279, Percent_Identity=39.7849462365591, Blast_Score=176, Evalue=8e-45,
Organism=Saccharomyces cerevisiae, GI6323429, Length=263, Percent_Identity=38.0228136882129, Blast_Score=170, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6322651, Length=238, Percent_Identity=37.3949579831933, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6322994, Length=231, Percent_Identity=37.2294372294372, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6321465, Length=240, Percent_Identity=39.1666666666667, Blast_Score=141, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6325431, Length=340, Percent_Identity=31.4705882352941, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319554, Length=213, Percent_Identity=38.0281690140845, Blast_Score=135, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6325183, Length=261, Percent_Identity=34.0996168582375, Blast_Score=130, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6320887, Length=260, Percent_Identity=34.6153846153846, Blast_Score=123, Evalue=7e-29,
Organism=Drosophila melanogaster, GI28574878, Length=640, Percent_Identity=41.5625, Blast_Score=468, Evalue=1e-132,
Organism=Drosophila melanogaster, GI24665814, Length=640, Percent_Identity=41.09375, Blast_Score=468, Evalue=1e-132,
Organism=Drosophila melanogaster, GI24658770, Length=486, Percent_Identity=47.7366255144033, Blast_Score=447, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24639391, Length=465, Percent_Identity=47.0967741935484, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI17137560, Length=285, Percent_Identity=40.7017543859649, Blast_Score=220, Evalue=3e-57,
Organism=Drosophila melanogaster, GI161076486, Length=285, Percent_Identity=40.7017543859649, Blast_Score=220, Evalue=3e-57,
Organism=Drosophila melanogaster, GI161076488, Length=285, Percent_Identity=40.7017543859649, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI17137738, Length=254, Percent_Identity=42.1259842519685, Blast_Score=213, Evalue=4e-55,
Organism=Drosophila melanogaster, GI19920408, Length=257, Percent_Identity=40.8560311284047, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI45554047, Length=165, Percent_Identity=59.3939393939394, Blast_Score=209, Evalue=7e-54,
Organism=Drosophila melanogaster, GI24651451, Length=255, Percent_Identity=41.5686274509804, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24649446, Length=245, Percent_Identity=41.6326530612245, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24652279, Length=248, Percent_Identity=41.5322580645161, Blast_Score=199, Evalue=5e-51,
Organism=Drosophila melanogaster, GI24640100, Length=245, Percent_Identity=40.8163265306122, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI17738151, Length=236, Percent_Identity=43.2203389830509, Blast_Score=196, Evalue=5e-50,
Organism=Drosophila melanogaster, GI18860063, Length=251, Percent_Identity=41.8326693227092, Blast_Score=192, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24663015, Length=250, Percent_Identity=40.8, Blast_Score=192, Evalue=6e-49,
Organism=Drosophila melanogaster, GI19921202, Length=245, Percent_Identity=42.4489795918367, Blast_Score=192, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24660075, Length=260, Percent_Identity=39.2307692307692, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281365776, Length=260, Percent_Identity=39.2307692307692, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI45552965, Length=260, Percent_Identity=39.2307692307692, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281361487, Length=247, Percent_Identity=40.080971659919, Blast_Score=186, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24656820, Length=227, Percent_Identity=41.4096916299559, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24656825, Length=227, Percent_Identity=41.4096916299559, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI281363136, Length=235, Percent_Identity=40, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI78707192, Length=235, Percent_Identity=40, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24644145, Length=233, Percent_Identity=39.0557939914163, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24581396, Length=234, Percent_Identity=40.5982905982906, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281360136, Length=230, Percent_Identity=37.3913043478261, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24644411, Length=230, Percent_Identity=37.3913043478261, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281360144, Length=230, Percent_Identity=37.3913043478261, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI281360140, Length=230, Percent_Identity=37.3913043478261, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI281360146, Length=230, Percent_Identity=37.3913043478261, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI281360138, Length=230, Percent_Identity=37.3913043478261, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI281360142, Length=230, Percent_Identity=37.3913043478261, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21357333, Length=230, Percent_Identity=37.3913043478261, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21355121, Length=215, Percent_Identity=37.6744186046512, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI18859657, Length=235, Percent_Identity=38.2978723404255, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28571849, Length=248, Percent_Identity=38.7096774193548, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI28571847, Length=248, Percent_Identity=38.7096774193548, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI20129529, Length=270, Percent_Identity=34.4444444444444, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28573010, Length=214, Percent_Identity=39.7196261682243, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI17864540, Length=214, Percent_Identity=39.2523364485981, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI20129423, Length=233, Percent_Identity=35.1931330472103, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24639486, Length=247, Percent_Identity=34.412955465587, Blast_Score=113, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 70640; Mature: 70640

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMNDLTKNVLLWVVVAVVLMVVFQSFSPRIGGVIGNEPITYTQFLNEVDSGRIKSVNYT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCC
DESGLTVNAIRFKRTDGSEGLVYGPRDDKLVDVLYSKNIEMTRQKPSTGPGFWSLVLNFL
CCCCCEEEEEEEEECCCCCCCEECCCCCCHHHHHHHCCCCEECCCCCCCCHHHHHHHHHH
PVILIIGFWVFIMRQMQGGGAKGAMSFGKSRAKLQGDDQIKITFADVAGCDEAKEEVGEL
HHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHH
VDFLRDPTKFTKLGGKIPRGVLMVGPPGTGKTLLAKAIAGEAKVPFFSISGSDFVEMFVG
HHHHHCCHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHH
VGASRVRDMFEQAKKHAPCIIFIDEIDAVGRHRGAGLGGGHDEREQTLNQLLVEMDGFEG
CCHHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
GEGVIVIAATNRPDVLDPALLRPGRFDRQVVVALPDVKGREQILGVHMRKLLLANDVEPL
CCEEEEEEECCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCE
VIARGTPGFSGADLANLCNEAALFAARSNEKEVRMNHFDAARDKILMGTERRSMAMSEEE
EEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCHHHHHHCHHH
KTLTAYHEAGHAIVGRLVPEHDPVYKVTIIPRGRALGVTMYLPEGDKYSINKVAIQSQLC
HHHHHHHHHCHHHHHCCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHH
SLYGGRVAEELIFGEDKVTTGASNDIERVTKMARNMVTKWGLSDELGPVAYGEEEDEVFL
HHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
GRSVTQHKNVSDETARKIDEVVRSILDKAYARTKRILADNLDKLHAMSQLLLQYETIDAP
CCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QIDAIMEGRAPPPPVGWGKPSDNGSDDDMSKPRPLTTIVVPAEQV
CHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MRMNDLTKNVLLWVVVAVVLMVVFQSFSPRIGGVIGNEPITYTQFLNEVDSGRIKSVNYT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCC
DESGLTVNAIRFKRTDGSEGLVYGPRDDKLVDVLYSKNIEMTRQKPSTGPGFWSLVLNFL
CCCCCEEEEEEEEECCCCCCCEECCCCCCHHHHHHHCCCCEECCCCCCCCHHHHHHHHHH
PVILIIGFWVFIMRQMQGGGAKGAMSFGKSRAKLQGDDQIKITFADVAGCDEAKEEVGEL
HHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHH
VDFLRDPTKFTKLGGKIPRGVLMVGPPGTGKTLLAKAIAGEAKVPFFSISGSDFVEMFVG
HHHHHCCHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHH
VGASRVRDMFEQAKKHAPCIIFIDEIDAVGRHRGAGLGGGHDEREQTLNQLLVEMDGFEG
CCHHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
GEGVIVIAATNRPDVLDPALLRPGRFDRQVVVALPDVKGREQILGVHMRKLLLANDVEPL
CCEEEEEEECCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCE
VIARGTPGFSGADLANLCNEAALFAARSNEKEVRMNHFDAARDKILMGTERRSMAMSEEE
EEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCHHHHHHCHHH
KTLTAYHEAGHAIVGRLVPEHDPVYKVTIIPRGRALGVTMYLPEGDKYSINKVAIQSQLC
HHHHHHHHHCHHHHHCCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHH
SLYGGRVAEELIFGEDKVTTGASNDIERVTKMARNMVTKWGLSDELGPVAYGEEEDEVFL
HHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
GRSVTQHKNVSDETARKIDEVVRSILDKAYARTKRILADNLDKLHAMSQLLLQYETIDAP
CCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QIDAIMEGRAPPPPVGWGKPSDNGSDDDMSKPRPLTTIVVPAEQV
CHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]