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The map label for this gene is ffh [H]

Identifier: 182680619

GI number: 182680619

Start: 73003

End: 74370

Strand: Direct

Name: ffh [H]

Synonym: XfasM23_0047

Alternate gene names: 182680619

Gene position: 73003-74370 (Clockwise)

Preceding gene: 182680617

Following gene: 182680620

Centisome position: 2.88

GC content: 48.98

Gene sequence:

>1368_bases
ATGTTCGAGTCTCTCACTCAACGTCTTTCTGGAACCATTGAGCGTCTGCGTGGACGCGGTCGCTTGACGGAAGAGAATAT
CCGTGAAGCGACTCGTGAGGTTCGCATTGCTTTGCTTGAAGCTGATGTCGCTTTATCGGTCGTACAAGCCTTGATTGAGC
GTATCAAAATACGGGCCCTTGGCCAGGAAGTGCTTAAATCATTAACTCCAGGCCAAGCATTGATTAAAGTTGTACGGGAT
GAGCTGGCAGCTGTAATGGGTGACTCTGCCAGCGAATTGAATCTCAATGTTCCAGCACCTGCGGTCATATTACTTGCCGG
ATTACAGGGCGCAGGAAAAACCAGCATGGTTGGTAAGCTGGCTAAGTATTTGAAGGAAAAGCGTAAGAAGAAAGTCATGG
TAGTCAGTGCTGATGTCTATCGTCCGGCTGCAATCGAGCAACTTAGGATCCTTTCTGAACAGGTGAATGTGTTGTGCTTC
CCATCAAGTGTGGAGCAGAATCCAGTTGATATAGTGCGTGCTGCAATTGCTGATGCCAAGAAGTCTTTTGTTGATGTGCT
CTTGGTTGATACTGCTGGCCGCTTAGCGATTGATCAAGGGATGATGGATGAGATCAAGGCGCTGCATGACACGCTTGTTC
CTGTGGAGACCTTGTTTGTAGTTGACAGTATGACTGGCCAGGACGCTGCTAACACTGCCAAGGCATTTAGTGAAGCCTTG
CCACTGACAGGTTTAATACTAACCAAAACCGACGGTGATGCACGTGGAGGTGGTGCTCTGAGTGTGCGTTACATCACTGG
GCGTCCGATCAAATTTGTTGGTACTGGTGAGAAGGTCGATGACCTGGATGTTTTCCATCCAGACCGTGCTGCTAAGCGCA
TCCTTGACATGGGGGATGTGTTGTCACTTGTCGAGCAGGTCGAACAGGCAGTTGATCAGGAGAAAACTGCCAAGCTTGCT
GCGAAGGTGGCGAAGGGGAAGAAGTTCAATCTGAATGATATGAAGGAACAGCTAGAACAGATGCAGAATATGGGAGGGAT
TAATAGTTTGATGGATAAGCTTCCGGGGATGGGGCAGATTCCTGATCATCTCAAGCAGCAAGTCACTGGCAAGGAAGTGC
CACGCATGATTGCGATCATTAACTCTATGACTCAGAAGGAGCGTCGTAATCCGACTCTACTTAACGGCTCGCGCCGTGTC
CGCATTGCTAAGGGGTCCGGTCTACAGCCTTCCGATGTGAATAAATTGATGAAGCAGTACCAACAGATGGAGAAAATGAT
GTCAAAACTTTCTGGTGGTGGTATGAAAGGATTGATGCGGGGAATGATGGGTGCCATGGGTGGTCGTGGAAGGCTACCGT
TTCGTTGA

Upstream 100 bases:

>100_bases
AATAACAACAATTATCACCTCACATAATGTAAACCTTTGGGCAGGACTGACAGAGGAGTCGTTATAATCCTCACTCTGTT
TTCCTTTACGTTTATATCTT

Downstream 100 bases:

>100_bases
TGAAGCCGGTGCTGATTCAGGTTCCTTTTATACCATTCTCGTATTTGATTGGATGCAGGGGTTGCAATTCACGTGTTCCT
GATCCAGTGATAGAGAGAGG

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MFESLTQRLSGTIERLRGRGRLTEENIREATREVRIALLEADVALSVVQALIERIKIRALGQEVLKSLTPGQALIKVVRD
ELAAVMGDSASELNLNVPAPAVILLAGLQGAGKTSMVGKLAKYLKEKRKKKVMVVSADVYRPAAIEQLRILSEQVNVLCF
PSSVEQNPVDIVRAAIADAKKSFVDVLLVDTAGRLAIDQGMMDEIKALHDTLVPVETLFVVDSMTGQDAANTAKAFSEAL
PLTGLILTKTDGDARGGGALSVRYITGRPIKFVGTGEKVDDLDVFHPDRAAKRILDMGDVLSLVEQVEQAVDQEKTAKLA
AKVAKGKKFNLNDMKEQLEQMQNMGGINSLMDKLPGMGQIPDHLKQQVTGKEVPRMIAIINSMTQKERRNPTLLNGSRRV
RIAKGSGLQPSDVNKLMKQYQQMEKMMSKLSGGGMKGLMRGMMGAMGGRGRLPFR

Sequences:

>Translated_455_residues
MFESLTQRLSGTIERLRGRGRLTEENIREATREVRIALLEADVALSVVQALIERIKIRALGQEVLKSLTPGQALIKVVRD
ELAAVMGDSASELNLNVPAPAVILLAGLQGAGKTSMVGKLAKYLKEKRKKKVMVVSADVYRPAAIEQLRILSEQVNVLCF
PSSVEQNPVDIVRAAIADAKKSFVDVLLVDTAGRLAIDQGMMDEIKALHDTLVPVETLFVVDSMTGQDAANTAKAFSEAL
PLTGLILTKTDGDARGGGALSVRYITGRPIKFVGTGEKVDDLDVFHPDRAAKRILDMGDVLSLVEQVEQAVDQEKTAKLA
AKVAKGKKFNLNDMKEQLEQMQNMGGINSLMDKLPGMGQIPDHLKQQVTGKEVPRMIAIINSMTQKERRNPTLLNGSRRV
RIAKGSGLQPSDVNKLMKQYQQMEKMMSKLSGGGMKGLMRGMMGAMGGRGRLPFR
>Mature_455_residues
MFESLTQRLSGTIERLRGRGRLTEENIREATREVRIALLEADVALSVVQALIERIKIRALGQEVLKSLTPGQALIKVVRD
ELAAVMGDSASELNLNVPAPAVILLAGLQGAGKTSMVGKLAKYLKEKRKKKVMVVSADVYRPAAIEQLRILSEQVNVLCF
PSSVEQNPVDIVRAAIADAKKSFVDVLLVDTAGRLAIDQGMMDEIKALHDTLVPVETLFVVDSMTGQDAANTAKAFSEAL
PLTGLILTKTDGDARGGGALSVRYITGRPIKFVGTGEKVDDLDVFHPDRAAKRILDMGDVLSLVEQVEQAVDQEKTAKLA
AKVAKGKKFNLNDMKEQLEQMQNMGGINSLMDKLPGMGQIPDHLKQQVTGKEVPRMIAIINSMTQKERRNPTLLNGSRRV
RIAKGSGLQPSDVNKLMKQYQQMEKMMSKLSGGGMKGLMRGMMGAMGGRGRLPFR

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=450, Percent_Identity=29.3333333333333, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI226371618, Length=353, Percent_Identity=31.1614730878187, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI23308697, Length=309, Percent_Identity=26.8608414239482, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI89061728, Length=148, Percent_Identity=33.7837837837838, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI295424842, Length=309, Percent_Identity=26.8608414239482, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1788963, Length=446, Percent_Identity=63.677130044843, Blast_Score=553, Evalue=1e-159,
Organism=Escherichia coli, GI1789874, Length=229, Percent_Identity=37.117903930131, Blast_Score=152, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17539958, Length=428, Percent_Identity=28.7383177570093, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI193206261, Length=201, Percent_Identity=34.8258706467662, Blast_Score=104, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6325345, Length=427, Percent_Identity=32.7868852459016, Blast_Score=218, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6320498, Length=212, Percent_Identity=29.2452830188679, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17647949, Length=444, Percent_Identity=29.954954954955, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24641198, Length=248, Percent_Identity=30.241935483871, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 49565; Mature: 49565

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS00589 PTS_HPR_SER ; PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFESLTQRLSGTIERLRGRGRLTEENIREATREVRIALLEADVALSVVQALIERIKIRAL
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQEVLKSLTPGQALIKVVRDELAAVMGDSASELNLNVPAPAVILLAGLQGAGKTSMVGKL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHCCCCCCCHHHHHHH
AKYLKEKRKKKVMVVSADVYRPAAIEQLRILSEQVNVLCFPSSVEQNPVDIVRAAIADAK
HHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHH
KSFVDVLLVDTAGRLAIDQGMMDEIKALHDTLVPVETLFVVDSMTGQDAANTAKAFSEAL
HHHHHHHEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
PLTGLILTKTDGDARGGGALSVRYITGRPIKFVGTGEKVDDLDVFHPDRAAKRILDMGDV
CCCEEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LSLVEQVEQAVDQEKTAKLAAKVAKGKKFNLNDMKEQLEQMQNMGGINSLMDKLPGMGQI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
PDHLKQQVTGKEVPRMIAIINSMTQKERRNPTLLNGSRRVRIAKGSGLQPSDVNKLMKQY
CHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCCCCHHHHHHHHHHH
QQMEKMMSKLSGGGMKGLMRGMMGAMGGRGRLPFR
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFESLTQRLSGTIERLRGRGRLTEENIREATREVRIALLEADVALSVVQALIERIKIRAL
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQEVLKSLTPGQALIKVVRDELAAVMGDSASELNLNVPAPAVILLAGLQGAGKTSMVGKL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHCCCCCCCHHHHHHH
AKYLKEKRKKKVMVVSADVYRPAAIEQLRILSEQVNVLCFPSSVEQNPVDIVRAAIADAK
HHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHH
KSFVDVLLVDTAGRLAIDQGMMDEIKALHDTLVPVETLFVVDSMTGQDAANTAKAFSEAL
HHHHHHHEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
PLTGLILTKTDGDARGGGALSVRYITGRPIKFVGTGEKVDDLDVFHPDRAAKRILDMGDV
CCCEEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LSLVEQVEQAVDQEKTAKLAAKVAKGKKFNLNDMKEQLEQMQNMGGINSLMDKLPGMGQI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
PDHLKQQVTGKEVPRMIAIINSMTQKERRNPTLLNGSRRVRIAKGSGLQPSDVNKLMKQY
CHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEECCCCCCHHHHHHHHHHH
QQMEKMMSKLSGGGMKGLMRGMMGAMGGRGRLPFR
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]