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The map label for this gene is fmt [H]

Identifier: 182677493

GI number: 182677493

Start: 555008

End: 555961

Strand: Direct

Name: fmt [H]

Synonym: Bind_0497

Alternate gene names: 182677493

Gene position: 555008-555961 (Clockwise)

Preceding gene: 182677492

Following gene: 182677494

Centisome position: 13.31

GC content: 63.1

Gene sequence:

>954_bases
ATGGGAACGCCGGTTTTTTCCGTGCCGGTTCTGAATGCCCTGATCGAAGCGGGGCATCAGGTGGCGGCGGTCTATACGCG
AGCGCCACGGCCTGCGGGGCGGCGCGGCCTGGATCTGACGCCGTCGCCCGTCCATCTCGCGGCGCAGCAGCATGATTTGC
CCGTCGAGACGCCCAAAAGCCTGCGATCGGAAGAGGCTCTCGCGACTTTGCGCGCCTATGCGCCGGATGTTCTGGTCGTG
GTTGCTTATGGGCTCATCCTGCCCAAAGCCATTCTCGATGTTCCGCCGTTTGGCGCGCTCAATCTCCATGCCTCGCTGCT
GCCGCGCTGGCGGGGAGCCGCGCCGATTCAGCGGGCGATCATGGCAGGCGATAGCCAGTCCGGCATTGAGCTCATGCGGA
TGGAAGAGGGACTCGATACCGGGCCCGTCGGGCTTGTCGGCGAAGTGACCATTGGCCCCGACATGACCGGCGGCGAATTG
CATGATCTTCTCTCGCTTCGCGCCGCCACGCTCATCATCGAGGGGCTGCAAAAGCTGGAAGCTGGAACGCTGACGTTCAC
GCCGCAGACCGAGGACGGGGTGATCTATGCCAAGAAGATCGAAAAGGTCGAGGCGCGGATCGATTGGCGGCGGCCCGCTC
ACGAGGTTTATAATCTCATCCGCGCCCTTTCGCCTTTCCCTGGTGCTTTCTTCGAGGTGGATCTCGGCAAGGGGTTGGAG
CGCATCAAGATTCTGCGGGCAGAACTCACACACACGCCTGCCGCGCAGCCCGGTGAAATCCTTGATGCGGGCCTGAGCAT
AGCCTGTGGCGAGGGGGAAGGGAGCGGCGCGATCAAGCTTCTCGATATTCAACGGTCCGGCAAAGCACCCATGAGCGCCG
AGGCCTTTTTGCGCGGCACGAAACTGCCTGCCAGCACCCGATTGCCGCTGCCCGATCTCCATGCCCCGCTATAA

Upstream 100 bases:

>100_bases
GCAAGGCGGATAGCGAAGCCTGAGTTTTCCGAGTGACTGATCCGCTTCCGACGTAACGAGCGAAGCTCAAAGACGAAGGT
TTCCCTTGCGCGTCGTGTTT

Downstream 100 bases:

>100_bases
ATTAACTGTCGAATATGACGGCGCGTCCTTTGTGGGTTGGCAGAGGCAGAAGAATGGGCTCTCGGTTCAGGAAGTGATCG
AGACGGCTCTCTTGGCCATC

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MGTPVFSVPVLNALIEAGHQVAAVYTRAPRPAGRRGLDLTPSPVHLAAQQHDLPVETPKSLRSEEALATLRAYAPDVLVV
VAYGLILPKAILDVPPFGALNLHASLLPRWRGAAPIQRAIMAGDSQSGIELMRMEEGLDTGPVGLVGEVTIGPDMTGGEL
HDLLSLRAATLIIEGLQKLEAGTLTFTPQTEDGVIYAKKIEKVEARIDWRRPAHEVYNLIRALSPFPGAFFEVDLGKGLE
RIKILRAELTHTPAAQPGEILDAGLSIACGEGEGSGAIKLLDIQRSGKAPMSAEAFLRGTKLPASTRLPLPDLHAPL

Sequences:

>Translated_317_residues
MGTPVFSVPVLNALIEAGHQVAAVYTRAPRPAGRRGLDLTPSPVHLAAQQHDLPVETPKSLRSEEALATLRAYAPDVLVV
VAYGLILPKAILDVPPFGALNLHASLLPRWRGAAPIQRAIMAGDSQSGIELMRMEEGLDTGPVGLVGEVTIGPDMTGGEL
HDLLSLRAATLIIEGLQKLEAGTLTFTPQTEDGVIYAKKIEKVEARIDWRRPAHEVYNLIRALSPFPGAFFEVDLGKGLE
RIKILRAELTHTPAAQPGEILDAGLSIACGEGEGSGAIKLLDIQRSGKAPMSAEAFLRGTKLPASTRLPLPDLHAPL
>Mature_316_residues
GTPVFSVPVLNALIEAGHQVAAVYTRAPRPAGRRGLDLTPSPVHLAAQQHDLPVETPKSLRSEEALATLRAYAPDVLVVV
AYGLILPKAILDVPPFGALNLHASLLPRWRGAAPIQRAIMAGDSQSGIELMRMEEGLDTGPVGLVGEVTIGPDMTGGELH
DLLSLRAATLIIEGLQKLEAGTLTFTPQTEDGVIYAKKIEKVEARIDWRRPAHEVYNLIRALSPFPGAFFEVDLGKGLER
IKILRAELTHTPAAQPGEILDAGLSIACGEGEGSGAIKLLDIQRSGKAPMSAEAFLRGTKLPASTRLPLPDLHAPL

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI238814322, Length=240, Percent_Identity=28.75, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI21614513, Length=238, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI164663775, Length=183, Percent_Identity=32.2404371584699, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1789683, Length=304, Percent_Identity=42.4342105263158, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1788589, Length=265, Percent_Identity=29.4339622641509, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI133930964, Length=244, Percent_Identity=26.2295081967213, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319458, Length=300, Percent_Identity=26, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550868, Length=303, Percent_Identity=31.6831683168317, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28571984, Length=228, Percent_Identity=35.0877192982456, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24585660, Length=323, Percent_Identity=24.4582043343653, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 33762; Mature: 33630

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTPVFSVPVLNALIEAGHQVAAVYTRAPRPAGRRGLDLTPSPVHLAAQQHDLPVETPKS
CCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHH
LRSEEALATLRAYAPDVLVVVAYGLILPKAILDVPPFGALNLHASLLPRWRGAAPIQRAI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHH
MAGDSQSGIELMRMEEGLDTGPVGLVGEVTIGPDMTGGELHDLLSLRAATLIIEGLQKLE
HCCCCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHC
AGTLTFTPQTEDGVIYAKKIEKVEARIDWRRPAHEVYNLIRALSPFPGAFFEVDLGKGLE
CCEEEECCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEHHCCHH
RIKILRAELTHTPAAQPGEILDAGLSIACGEGEGSGAIKLLDIQRSGKAPMSAEAFLRGT
HHHHHHHHHCCCCCCCCCHHHHCCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHCCC
KLPASTRLPLPDLHAPL
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GTPVFSVPVLNALIEAGHQVAAVYTRAPRPAGRRGLDLTPSPVHLAAQQHDLPVETPKS
CCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHH
LRSEEALATLRAYAPDVLVVVAYGLILPKAILDVPPFGALNLHASLLPRWRGAAPIQRAI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHH
MAGDSQSGIELMRMEEGLDTGPVGLVGEVTIGPDMTGGELHDLLSLRAATLIIEGLQKLE
HCCCCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHC
AGTLTFTPQTEDGVIYAKKIEKVEARIDWRRPAHEVYNLIRALSPFPGAFFEVDLGKGLE
CCEEEECCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEHHCCHH
RIKILRAELTHTPAAQPGEILDAGLSIACGEGEGSGAIKLLDIQRSGKAPMSAEAFLRGT
HHHHHHHHHCCCCCCCCCHHHHCCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHCCC
KLPASTRLPLPDLHAPL
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA