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The map label for this gene is fixC [H]

Identifier: 182677485

GI number: 182677485

Start: 549380

End: 550681

Strand: Direct

Name: fixC [H]

Synonym: Bind_0489

Alternate gene names: 182677485

Gene position: 549380-550681 (Clockwise)

Preceding gene: 182677484

Following gene: 182677486

Centisome position: 13.17

GC content: 56.53

Gene sequence:

>1302_bases
ATGGCGGACGAAAAATTCGATGCGATCGTCGTAGGCGCCGGACCCTCCGGAAATGCTTGCGCTTATACTCTGGCCACCCG
TGGCCTCAAGGTCCTGCAATTGGAGCGCGGTGAATATCCGGGCTCCAAGAATGTGCAGGGTGCCATTCTCTATGCCGATG
CGCTGGAAAAGATCATTCCTGATTTCCGCGAGGATGCGCCGCTTGAGCGACACATTATCGAACAGCGCCTTTGGATGATG
GATGATAAATCCTATTGCGGCGCGCATTACCGGTCCGAGGATTTCAACGAGGACAAGCCGAACCGCTATACGATCATCCG
CGCGCCCTTCGACAAGTGGTTTTCTCGCCGTGTTTCAGAGGCAGGCGCCCTGATCCTGTGCGAAACCACGGTGACCGAAT
TGGTTCGCGATGCCCATGACAAGGTCATCGGTGTCCGCACCGATCGCGACGGCGCGGCGATCTATGCCGATATTGTCGTC
CTGGCGGAAGGCGTCAGCGGTCTCGTCGGCGCCCGCGCGGGCCTGCGGTCCATTCCGAAGCCCGATACGGTCGCGCTCGC
GGTCAAGGAAATGCACTTCCTGCCGCGCGAGACCATCGAAGCCCGCTTCAACCTCCAGGGTGATGAAGGTGTGGTGATCG
AATCCGCTGGGACGATCACCAAGGGCATGGCCGGTACGGGCTTCCTCTATACCAATAAGGAATGTATCTCGATCGGCATC
GGTTGCCTCATTTCGGATTTCACCAATAGCGATCAGACGCCTTACGGTCTGCTCGAAGCGTTCAAGCAGCATCCTTCCGT
CAAGCCCTTGCTCGCAGGGTCCGAGGTCAAGGAATATGCGGCGCATATGATTCCGGAAGGCGGCTATAAGGCCATTCCGC
AATTGTTCGGCAATGGCTGGCTGATCGTCGGCGATGCGGGACAATTCGTGAATGCGATCCATCGTGAAGGCTCCAACCTC
GCCATGACGACGGGCCGCATCGCCGCTGAAACCATTCTGGATCTCAAAACCCGGAATGCGCCAATGACGGCGAATAATCT
GGCCGCCTACAAGACTCGGCTTGATGAATCTTTCGTCATGAAAGATTTGAAGAAATATAAAAACCTGCCGAATGCTTTCC
ATAACAAGCATTTGTTCACGACTTATCCGCAGCTCATTTCCAAGGCAGCGCAGACCTGGTTCCGGGTCGATGGCGTGGAC
AAAAAAGCCAAGGAAAACGAGATCTTGAAATCCTTCTTCCGCACGCGGCGCGTCAAGGGTCTGCTTGGCGACGTGCTCGG
AATGGCGCGTGGCTGGCGCTAA

Upstream 100 bases:

>100_bases
TCGCGGATGCAACGAAAATATTGCCGGCGCTCACGGAAGCTTTCCGCAAGCGTCTCGCCCTGGCCGCCGCCCGGCCCGCG
GCTGAGTAAAGGAGACGGAC

Downstream 100 bases:

>100_bases
GTACAATTGGAAACGCCAGTCACGGATCAGATCCGCGTTTTCTCGTGAGGAATAAAGATGAGCACTGAAACCGAAACCAA
TGTTCGCGTGGAAGACAAGC

Product: electron-transferring-flavoprotein dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MADEKFDAIVVGAGPSGNACAYTLATRGLKVLQLERGEYPGSKNVQGAILYADALEKIIPDFREDAPLERHIIEQRLWMM
DDKSYCGAHYRSEDFNEDKPNRYTIIRAPFDKWFSRRVSEAGALILCETTVTELVRDAHDKVIGVRTDRDGAAIYADIVV
LAEGVSGLVGARAGLRSIPKPDTVALAVKEMHFLPRETIEARFNLQGDEGVVIESAGTITKGMAGTGFLYTNKECISIGI
GCLISDFTNSDQTPYGLLEAFKQHPSVKPLLAGSEVKEYAAHMIPEGGYKAIPQLFGNGWLIVGDAGQFVNAIHREGSNL
AMTTGRIAAETILDLKTRNAPMTANNLAAYKTRLDESFVMKDLKKYKNLPNAFHNKHLFTTYPQLISKAAQTWFRVDGVD
KKAKENEILKSFFRTRRVKGLLGDVLGMARGWR

Sequences:

>Translated_433_residues
MADEKFDAIVVGAGPSGNACAYTLATRGLKVLQLERGEYPGSKNVQGAILYADALEKIIPDFREDAPLERHIIEQRLWMM
DDKSYCGAHYRSEDFNEDKPNRYTIIRAPFDKWFSRRVSEAGALILCETTVTELVRDAHDKVIGVRTDRDGAAIYADIVV
LAEGVSGLVGARAGLRSIPKPDTVALAVKEMHFLPRETIEARFNLQGDEGVVIESAGTITKGMAGTGFLYTNKECISIGI
GCLISDFTNSDQTPYGLLEAFKQHPSVKPLLAGSEVKEYAAHMIPEGGYKAIPQLFGNGWLIVGDAGQFVNAIHREGSNL
AMTTGRIAAETILDLKTRNAPMTANNLAAYKTRLDESFVMKDLKKYKNLPNAFHNKHLFTTYPQLISKAAQTWFRVDGVD
KKAKENEILKSFFRTRRVKGLLGDVLGMARGWR
>Mature_432_residues
ADEKFDAIVVGAGPSGNACAYTLATRGLKVLQLERGEYPGSKNVQGAILYADALEKIIPDFREDAPLERHIIEQRLWMMD
DKSYCGAHYRSEDFNEDKPNRYTIIRAPFDKWFSRRVSEAGALILCETTVTELVRDAHDKVIGVRTDRDGAAIYADIVVL
AEGVSGLVGARAGLRSIPKPDTVALAVKEMHFLPRETIEARFNLQGDEGVVIESAGTITKGMAGTGFLYTNKECISIGIG
CLISDFTNSDQTPYGLLEAFKQHPSVKPLLAGSEVKEYAAHMIPEGGYKAIPQLFGNGWLIVGDAGQFVNAIHREGSNLA
MTTGRIAAETILDLKTRNAPMTANNLAAYKTRLDESFVMKDLKKYKNLPNAFHNKHLFTTYPQLISKAAQTWFRVDGVDK
KAKENEILKSFFRTRRVKGLLGDVLGMARGWR

Specific function: Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from fixA/fixB and reduces a quinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=407, Percent_Identity=24.3243243243243, Blast_Score=113, Evalue=4e-25,
Organism=Escherichia coli, GI1787991, Length=400, Percent_Identity=38.25, Blast_Score=282, Evalue=4e-77,
Organism=Escherichia coli, GI1786227, Length=413, Percent_Identity=39.225181598063, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI87082155, Length=416, Percent_Identity=33.8942307692308, Blast_Score=216, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI25144720, Length=400, Percent_Identity=24.25, Blast_Score=112, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324932, Length=447, Percent_Identity=25.2796420581655, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24652256, Length=402, Percent_Identity=24.8756218905473, Blast_Score=108, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.5.5.-

Molecular weight: Translated: 47866; Mature: 47735

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADEKFDAIVVGAGPSGNACAYTLATRGLKVLQLERGEYPGSKNVQGAILYADALEKIIP
CCCCCCCEEEEECCCCCCCEEEHHHHCCEEEEEEECCCCCCCCCCCEEEEEHHHHHHHCC
DFREDAPLERHIIEQRLWMMDDKSYCGAHYRSEDFNEDKPNRYTIIRAPFDKWFSRRVSE
HHHCCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHH
AGALILCETTVTELVRDAHDKVIGVRTDRDGAAIYADIVVLAEGVSGLVGARAGLRSIPK
CCCEEEEHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDTVALAVKEMHFLPRETIEARFNLQGDEGVVIESAGTITKGMAGTGFLYTNKECISIGI
CCHHHHHHHHHHHCCHHHHHHEEECCCCCCEEEECCCCHHCCCCCCCEEEECHHHHHHHH
GCLISDFTNSDQTPYGLLEAFKQHPSVKPLLAGSEVKEYAAHMIPEGGYKAIPQLFGNGW
HHHHHCCCCCCCCCHHHHHHHHHCCCCCCEECCHHHHHHHHHHCCCCCHHHHHHHHCCCE
LIVGDAGQFVNAIHREGSNLAMTTGRIAAETILDLKTRNAPMTANNLAAYKTRLDESFVM
EEEECCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHH
KDLKKYKNLPNAFHNKHLFTTYPQLISKAAQTWFRVDGVDKKAKENEILKSFFRTRRVKG
HHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHH
LLGDVLGMARGWR
HHHHHHHHHCCCC
>Mature Secondary Structure 
ADEKFDAIVVGAGPSGNACAYTLATRGLKVLQLERGEYPGSKNVQGAILYADALEKIIP
CCCCCCEEEEECCCCCCCEEEHHHHCCEEEEEEECCCCCCCCCCCEEEEEHHHHHHHCC
DFREDAPLERHIIEQRLWMMDDKSYCGAHYRSEDFNEDKPNRYTIIRAPFDKWFSRRVSE
HHHCCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHH
AGALILCETTVTELVRDAHDKVIGVRTDRDGAAIYADIVVLAEGVSGLVGARAGLRSIPK
CCCEEEEHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDTVALAVKEMHFLPRETIEARFNLQGDEGVVIESAGTITKGMAGTGFLYTNKECISIGI
CCHHHHHHHHHHHCCHHHHHHEEECCCCCCEEEECCCCHHCCCCCCCEEEECHHHHHHHH
GCLISDFTNSDQTPYGLLEAFKQHPSVKPLLAGSEVKEYAAHMIPEGGYKAIPQLFGNGW
HHHHHCCCCCCCCCHHHHHHHHHCCCCCCEECCHHHHHHHHHHCCCCCHHHHHHHHCCCE
LIVGDAGQFVNAIHREGSNLAMTTGRIAAETILDLKTRNAPMTANNLAAYKTRLDESFVM
EEEECCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHH
KDLKKYKNLPNAFHNKHLFTTYPQLISKAAQTWFRVDGVDKKAKENEILKSFFRTRRVKG
HHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHH
LLGDVLGMARGWR
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1850088 [H]