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The map label for this gene is glpD2 [H]

Identifier: 182677374

GI number: 182677374

Start: 435676

End: 437295

Strand: Direct

Name: glpD2 [H]

Synonym: Bind_0378

Alternate gene names: 182677374

Gene position: 435676-437295 (Clockwise)

Preceding gene: 182677370

Following gene: 182677375

Centisome position: 10.45

GC content: 59.26

Gene sequence:

>1620_bases
ATGGACAGGCAGGCGGCTCTCAAAGCCCTTCAGGCCGGTGAGACATTTGATCTCCTGGTCGTGGGTGGTGGTGCGACAGG
CTGTGGCGTGGCGCTTGATGCGGCCAGCCGCGGGCTGAAAGTGGCGCTGGTCGAACGCAATGATTTCGCTGAAGGGACCA
GCAGCAAAAGCACCAAGCTGGTGCATGGTGGCGCCCGCTATCTGGAACTAGCGATCCGCCGGCTTGACCGCGTGCAGTTC
AACCTGGTTCGCGATGGCCTGCGCGAACGCGCCATTTTCCTGAAAAATGCCCCCCATCTCGCCCATCGCCTGGCCCTTCT
ATCGCCGCTCTATCGCTGGTTCGATGTGCCTTATGTCTTCGCCGGCCTTTATCTCTATGATCGCCTGGCCGGAAAACTTG
GCCTTGGTGGAAGCCGCCTCTTGAGCCGCGCCGAGGCCTTGCGCCGCTTTCCCATGCTGAAGGCTGAAGGCTTGAAAGCG
GCTGTCCTCTATTATGATGGGCAATTCAATGATGCCCGCATGGCGGTGACATTGGCGCTGACTGCCGTGGAACAGGGCGC
GGTGATTGCGACAAGGCTCGATGTGGTCGGTTTGACCCATGAGAAGGGCAAATTGAGGGGCGCGACGGTCCATGACCGGG
AAAGCAGAAAAAGCTTTGAGATAAAAGCGCGCGCGATCATCAATGCGGGCGGCCCCTTCGCCGATTCCCTGCGTCTCATG
GCCGATCCTGAAACCGCCCCCATACTCACCGCAAGTTCCGGCATTCATATTGTTCTGGACCGGCGTTTCGCACCGACTGA
AACGGGGTTGATGATTCCAGAAACTGAAGATGGGCGTTTGTTGTTCGTGCTTCCCTGGCAGGGGCATGCCTTGATCGGCA
CCACTGATGAGCCAGCCAGAATCGAAGAAAATCCGCAGGCGCGCCAGGAGGCGATAGACTATCTGCTCCGGCACGTACGG
AAATATTTCAACATGAATGTCACCGAAGCTGATCTTCTATCAGTCTGGTGCGGTCTGCGCCCGCTGGTCAGCGATCCCAA
GGCGGCGGATACAGCCCGGCTTGCGCGCGATCATATTATCGAAGTGAGCAAGAGCGGCCTTGTGACGATTTGCGGCGGCA
AATGGACGACATACCGCAAGATGGCCGAACAGACGGTCGATCATGCCATTGCCTGTTTCAGCCTGCCCACACACAGCAAA
TGCCGCACACTTGACTTGCCCTTGGTTGGTGCGCGCCATTTCGATGCTGCAGGCGGCGCTGCGGCGCTTACATCGACCTT
TGGTCTTTCGCCCGAGACGGCGGCTCATCTGCATCAGGCCTATGGCGACAGGGCCAAACAGGTTTTGGGCTGCGTGGACA
CATCCGCGATGAAAACGCTGTTGCATCCGCTCCATCCCTATCTTGAAGCGGAAGTTCTCTATAGCGCGCGGTTTGAGGCG
GCTCTTTCCGCCATGGATGTTCTGGCCCGGCGTCTGCCGCTGGCCTTGCTCGACCGCCAGGCGGCACGCGAAGCAGCCCC
CCGCGTCATTGCCATGCTCGCCACTGAATTGGCCTGGGATGAACAGCGTTGCGCCAACGAGGCGGCCGAGGTCGAACAAA
GGCTGAGTGAAGCCATTTGA

Upstream 100 bases:

>100_bases
TCTTCGGAAAATTATCCAATAAAGACCATGGTTTCAGTTTTTAGTTTCGTTTATGTTCGAAAACGAATATTGGGCATGGT
CGTGGATTGCGGGGAGGGAT

Downstream 100 bases:

>100_bases
AGGTCCTTTTCCGGGCGGGGTAACAGAGAGGCATGTATGCCGTTGCATAGGCTTACAAAGGGGCGATGCAGGCGGCAATC
ATGAATGAAAGAGCTGGGAC

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MDRQAALKALQAGETFDLLVVGGGATGCGVALDAASRGLKVALVERNDFAEGTSSKSTKLVHGGARYLELAIRRLDRVQF
NLVRDGLRERAIFLKNAPHLAHRLALLSPLYRWFDVPYVFAGLYLYDRLAGKLGLGGSRLLSRAEALRRFPMLKAEGLKA
AVLYYDGQFNDARMAVTLALTAVEQGAVIATRLDVVGLTHEKGKLRGATVHDRESRKSFEIKARAIINAGGPFADSLRLM
ADPETAPILTASSGIHIVLDRRFAPTETGLMIPETEDGRLLFVLPWQGHALIGTTDEPARIEENPQARQEAIDYLLRHVR
KYFNMNVTEADLLSVWCGLRPLVSDPKAADTARLARDHIIEVSKSGLVTICGGKWTTYRKMAEQTVDHAIACFSLPTHSK
CRTLDLPLVGARHFDAAGGAAALTSTFGLSPETAAHLHQAYGDRAKQVLGCVDTSAMKTLLHPLHPYLEAEVLYSARFEA
ALSAMDVLARRLPLALLDRQAAREAAPRVIAMLATELAWDEQRCANEAAEVEQRLSEAI

Sequences:

>Translated_539_residues
MDRQAALKALQAGETFDLLVVGGGATGCGVALDAASRGLKVALVERNDFAEGTSSKSTKLVHGGARYLELAIRRLDRVQF
NLVRDGLRERAIFLKNAPHLAHRLALLSPLYRWFDVPYVFAGLYLYDRLAGKLGLGGSRLLSRAEALRRFPMLKAEGLKA
AVLYYDGQFNDARMAVTLALTAVEQGAVIATRLDVVGLTHEKGKLRGATVHDRESRKSFEIKARAIINAGGPFADSLRLM
ADPETAPILTASSGIHIVLDRRFAPTETGLMIPETEDGRLLFVLPWQGHALIGTTDEPARIEENPQARQEAIDYLLRHVR
KYFNMNVTEADLLSVWCGLRPLVSDPKAADTARLARDHIIEVSKSGLVTICGGKWTTYRKMAEQTVDHAIACFSLPTHSK
CRTLDLPLVGARHFDAAGGAAALTSTFGLSPETAAHLHQAYGDRAKQVLGCVDTSAMKTLLHPLHPYLEAEVLYSARFEA
ALSAMDVLARRLPLALLDRQAAREAAPRVIAMLATELAWDEQRCANEAAEVEQRLSEAI
>Mature_539_residues
MDRQAALKALQAGETFDLLVVGGGATGCGVALDAASRGLKVALVERNDFAEGTSSKSTKLVHGGARYLELAIRRLDRVQF
NLVRDGLRERAIFLKNAPHLAHRLALLSPLYRWFDVPYVFAGLYLYDRLAGKLGLGGSRLLSRAEALRRFPMLKAEGLKA
AVLYYDGQFNDARMAVTLALTAVEQGAVIATRLDVVGLTHEKGKLRGATVHDRESRKSFEIKARAIINAGGPFADSLRLM
ADPETAPILTASSGIHIVLDRRFAPTETGLMIPETEDGRLLFVLPWQGHALIGTTDEPARIEENPQARQEAIDYLLRHVR
KYFNMNVTEADLLSVWCGLRPLVSDPKAADTARLARDHIIEVSKSGLVTICGGKWTTYRKMAEQTVDHAIACFSLPTHSK
CRTLDLPLVGARHFDAAGGAAALTSTFGLSPETAAHLHQAYGDRAKQVLGCVDTSAMKTLLHPLHPYLEAEVLYSARFEA
ALSAMDVLARRLPLALLDRQAAREAAPRVIAMLATELAWDEQRCANEAAEVEQRLSEAI

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=534, Percent_Identity=44.3820224719101, Blast_Score=462, Evalue=1e-130,
Organism=Homo sapiens, GI285002231, Length=534, Percent_Identity=44.3820224719101, Blast_Score=462, Evalue=1e-130,
Organism=Escherichia coli, GI2367226, Length=496, Percent_Identity=32.4596774193548, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1788574, Length=396, Percent_Identity=28.030303030303, Blast_Score=96, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17509253, Length=538, Percent_Identity=47.3977695167286, Blast_Score=464, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI115534726, Length=526, Percent_Identity=40.3041825095057, Blast_Score=410, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6322036, Length=583, Percent_Identity=36.7066895368782, Blast_Score=357, Evalue=3e-99,
Organism=Drosophila melanogaster, GI161077125, Length=532, Percent_Identity=45.8646616541353, Blast_Score=450, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24653942, Length=532, Percent_Identity=45.8646616541353, Blast_Score=450, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24653944, Length=532, Percent_Identity=45.8646616541353, Blast_Score=450, Evalue=1e-126,
Organism=Drosophila melanogaster, GI20130025, Length=532, Percent_Identity=45.8646616541353, Blast_Score=450, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24586295, Length=554, Percent_Identity=37.9061371841155, Blast_Score=330, Evalue=2e-90,
Organism=Drosophila melanogaster, GI19921278, Length=533, Percent_Identity=35.0844277673546, Blast_Score=301, Evalue=6e-82,
Organism=Drosophila melanogaster, GI45550977, Length=389, Percent_Identity=32.3907455012853, Blast_Score=208, Evalue=6e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 58881; Mature: 58881

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRQAALKALQAGETFDLLVVGGGATGCGVALDAASRGLKVALVERNDFAEGTSSKSTKL
CCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEHHCCCCEEEEEEECCCCCCCCCCCCCEE
VHGGARYLELAIRRLDRVQFNLVRDGLRERAIFLKNAPHLAHRLALLSPLYRWFDVPYVF
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHH
AGLYLYDRLAGKLGLGGSRLLSRAEALRRFPMLKAEGLKAAVLYYDGQFNDARMAVTLAL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEEEE
TAVEQGAVIATRLDVVGLTHEKGKLRGATVHDRESRKSFEIKARAIINAGGPFADSLRLM
EHHCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHCCEEE
ADPETAPILTASSGIHIVLDRRFAPTETGLMIPETEDGRLLFVLPWQGHALIGTTDEPAR
ECCCCCCEEEECCCEEEEEECCCCCCCCCEEEECCCCCEEEEEECCCCCEEEECCCCCCC
IEENPQARQEAIDYLLRHVRKYFNMNVTEADLLSVWCGLRPLVSDPKAADTARLARDHII
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
EVSKSGLVTICGGKWTTYRKMAEQTVDHAIACFSLPTHSKCRTLDLPLVGARHFDAAGGA
EECCCCEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCCCCEEECCCEECCCCCCCCCCH
AALTSTFGLSPETAAHLHQAYGDRAKQVLGCVDTSAMKTLLHPLHPYLEAEVLYSARFEA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSAMDVLARRLPLALLDRQAAREAAPRVIAMLATELAWDEQRCANEAAEVEQRLSEAI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDRQAALKALQAGETFDLLVVGGGATGCGVALDAASRGLKVALVERNDFAEGTSSKSTKL
CCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEHHCCCCEEEEEEECCCCCCCCCCCCCEE
VHGGARYLELAIRRLDRVQFNLVRDGLRERAIFLKNAPHLAHRLALLSPLYRWFDVPYVF
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHH
AGLYLYDRLAGKLGLGGSRLLSRAEALRRFPMLKAEGLKAAVLYYDGQFNDARMAVTLAL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEEEE
TAVEQGAVIATRLDVVGLTHEKGKLRGATVHDRESRKSFEIKARAIINAGGPFADSLRLM
EHHCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCHHHCCEEE
ADPETAPILTASSGIHIVLDRRFAPTETGLMIPETEDGRLLFVLPWQGHALIGTTDEPAR
ECCCCCCEEEECCCEEEEEECCCCCCCCCEEEECCCCCEEEEEECCCCCEEEECCCCCCC
IEENPQARQEAIDYLLRHVRKYFNMNVTEADLLSVWCGLRPLVSDPKAADTARLARDHII
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
EVSKSGLVTICGGKWTTYRKMAEQTVDHAIACFSLPTHSKCRTLDLPLVGARHFDAAGGA
EECCCCEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCCCCEEECCCEECCCCCCCCCCH
AALTSTFGLSPETAAHLHQAYGDRAKQVLGCVDTSAMKTLLHPLHPYLEAEVLYSARFEA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSAMDVLARRLPLALLDRQAAREAAPRVIAMLATELAWDEQRCANEAAEVEQRLSEAI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]