Click here to switch to the map view.

The map label for this gene is atpB [H]

Identifier: 17548040

GI number: 17548040

Start: 3585422

End: 3586345

Strand: Reverse

Name: atpB [H]

Synonym: RSc3323

Alternate gene names: 17548040

Gene position: 3586345-3585422 (Counterclockwise)

Preceding gene: 17548041

Following gene: 17548039

Centisome position: 96.5

GC content: 60.71

Gene sequence:

>924_bases
ATGTACCGCGAAGAATGTTTCGCAATATTGGACTGGGTCATCATGGCAACAGAAGTCGCAGAAGCCGCCGGCCACGCCGC
CGAGCACGCTCTCACGCCTTCCGCGTATATCGCGGAGCACTTGCAGAATTTCAATAGCATCGGTGGCAAGCAGACGTCGA
TCGTCGACTTCTCCGTCATCAACTGGGACACCATGTTCTGGTCGGTGCTGATGGGTGCGATCGGCCTGATCTTCCTGGGC
ATGGCCGCGCGCCGTGTCACCGCCGGCGTGCCGGGCCGCTTCCAGGCCTTCGTCGAGCTCGTCGTCGAGATGGTCGATGA
CCAGGCCAAGGGCATCATCCACGGTGACCGCACCTGGATCGCGCCGCTGGCGCTGATGGTGTTCGTGTGGGTCACGCTGA
TGAACGCGGTCGATTTGATCCCGGTGGACTGGGTCTTTGGTATCAACCACCTGCTGGAGTCTTTCGGCCTGCACGTGCCG
CACCACCGCGCGGTGGCCACGGCGGATCTGAACGGCACCTTTGGCATGTCCTTCGCCGTGCTGCTGCTGATGATCTACTA
CAGCTTCAAGATCAAGGGCGCGGGCGGCTTTGTGCACGAGCTGCTGTCGGCTCCGTTCGGCGCCAAGTGGTACCTCGCGC
CGTTCAACCTGATCCTCAACATCATCGAATTTCTCGCCAAGGCTGTGTCGCTGGGCATGCGGTTGTTCGGCAACATGTAC
GCGGGCGAGCTGGTGTTCCTGCTGATCGCGCTGCTTGGCTCGATCTGGACGTTCGGTGCCGATTTCTCGGCGCTGGGTTT
CGTGGGTCACGTGGTGGCCGGTGCAGCGTGGGCGATCTTCCACATCCTGATCGTGCTGCTGCAAGCCTTCATCTTCATGA
TGCTGACGCTGGTGTATATCGGCCAGGCACATGACCACCATTAA

Upstream 100 bases:

>100_bases
GTTCACTGCGCTGACACCCCGATCAAATAAGGTGGTGCGTTCGGGCCGCGTGCAGTCCGCGATCTCCAGGGCAACCTGGT
CGAATCGCGCGCGAGCCGGA

Downstream 100 bases:

>100_bases
GTTGCGGTTCAGGTTCTCCGGTTCCGTTAGGTTTTTCCAAGTTCTAAGTTCTTCGTCTTTCACGTAAAAAGGGAGTCATC
ATGCAAGCATTTCTCGCCAA

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MYREECFAILDWVIMATEVAEAAGHAAEHALTPSAYIAEHLQNFNSIGGKQTSIVDFSVINWDTMFWSVLMGAIGLIFLG
MAARRVTAGVPGRFQAFVELVVEMVDDQAKGIIHGDRTWIAPLALMVFVWVTLMNAVDLIPVDWVFGINHLLESFGLHVP
HHRAVATADLNGTFGMSFAVLLLMIYYSFKIKGAGGFVHELLSAPFGAKWYLAPFNLILNIIEFLAKAVSLGMRLFGNMY
AGELVFLLIALLGSIWTFGADFSALGFVGHVVAGAAWAIFHILIVLLQAFIFMMLTLVYIGQAHDHH

Sequences:

>Translated_307_residues
MYREECFAILDWVIMATEVAEAAGHAAEHALTPSAYIAEHLQNFNSIGGKQTSIVDFSVINWDTMFWSVLMGAIGLIFLG
MAARRVTAGVPGRFQAFVELVVEMVDDQAKGIIHGDRTWIAPLALMVFVWVTLMNAVDLIPVDWVFGINHLLESFGLHVP
HHRAVATADLNGTFGMSFAVLLLMIYYSFKIKGAGGFVHELLSAPFGAKWYLAPFNLILNIIEFLAKAVSLGMRLFGNMY
AGELVFLLIALLGSIWTFGADFSALGFVGHVVAGAAWAIFHILIVLLQAFIFMMLTLVYIGQAHDHH
>Mature_307_residues
MYREECFAILDWVIMATEVAEAAGHAAEHALTPSAYIAEHLQNFNSIGGKQTSIVDFSVINWDTMFWSVLMGAIGLIFLG
MAARRVTAGVPGRFQAFVELVVEMVDDQAKGIIHGDRTWIAPLALMVFVWVTLMNAVDLIPVDWVFGINHLLESFGLHVP
HHRAVATADLNGTFGMSFAVLLLMIYYSFKIKGAGGFVHELLSAPFGAKWYLAPFNLILNIIEFLAKAVSLGMRLFGNMY
AGELVFLLIALLGSIWTFGADFSALGFVGHVVAGAAWAIFHILIVLLQAFIFMMLTLVYIGQAHDHH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=290, Percent_Identity=44.1379310344828, Blast_Score=214, Evalue=6e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 33790; Mature: 33790

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYREECFAILDWVIMATEVAEAAGHAAEHALTPSAYIAEHLQNFNSIGGKQTSIVDFSVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHH
NWDTMFWSVLMGAIGLIFLGMAARRVTAGVPGRFQAFVELVVEMVDDQAKGIIHGDRTWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
APLALMVFVWVTLMNAVDLIPVDWVFGINHLLESFGLHVPHHRAVATADLNGTFGMSFAV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHH
LLLMIYYSFKIKGAGGFVHELLSAPFGAKWYLAPFNLILNIIEFLAKAVSLGMRLFGNMY
HHHHHHHHHHCCCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGELVFLLIALLGSIWTFGADFSALGFVGHVVAGAAWAIFHILIVLLQAFIFMMLTLVYI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQAHDHH
HCCCCCC
>Mature Secondary Structure
MYREECFAILDWVIMATEVAEAAGHAAEHALTPSAYIAEHLQNFNSIGGKQTSIVDFSVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHH
NWDTMFWSVLMGAIGLIFLGMAARRVTAGVPGRFQAFVELVVEMVDDQAKGIIHGDRTWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
APLALMVFVWVTLMNAVDLIPVDWVFGINHLLESFGLHVPHHRAVATADLNGTFGMSFAV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHH
LLLMIYYSFKIKGAGGFVHELLSAPFGAKWYLAPFNLILNIIEFLAKAVSLGMRLFGNMY
HHHHHHHHHHCCCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGELVFLLIALLGSIWTFGADFSALGFVGHVVAGAAWAIFHILIVLLQAFIFMMLTLVYI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQAHDHH
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA