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The map label for this gene is tcp [H]

Identifier: 17548024

GI number: 17548024

Start: 3568419

End: 3570359

Strand: Reverse

Name: tcp [H]

Synonym: RSc3307

Alternate gene names: 17548024

Gene position: 3570359-3568419 (Counterclockwise)

Preceding gene: 17548025

Following gene: 17548021

Centisome position: 96.07

GC content: 69.19

Gene sequence:

>1941_bases
TTGCGTGAGTCATCTCAAGTTCCCCGCTCCCCTGCCGTAGCTTTTTCCACGTGCGCATTCCGGCCGGCTGTCGCCGGAGT
GCGGTGTCGTCATCGCGGTACGCAGTCTGATTCGTCTCCAACCTCAAAGAAAAGAATCACGATGTCCTCTCTCCGCACCC
GCATCCTCGTCATCTCTTCGGCCACCGTGATCGGTGCGCTCGCGCTGTCGGGGGCCGCCACGTACGCCATCGTGCGCGCC
AGCACGCTGGCATCCATCGATCAGAACCTGACGGCCATCGCCAGCGGCAACACGCTGGCCATCGACAAGTGGGTGACAGC
CAAGGCCCAGGCCGTGAAGGCGACGGCGGAGGCGGTGGAGTACGGCGATCCGCATGGCCTGGTCAAGCACATGGGCGATG
CCGATGGCTTCCCGATCACCACCGTCGGCTGGACCGACAAGACGTTCTTCTCCACCAGCGCCGGCACGCCCAAGGACTAC
GATCCGACCGCCCGCCCCTGGTACAAGTCGGCCATCGCCGCCGGCAAGCCGACCGTCACCAAGCCTTACGGCGATGCGTC
GACCGGCGTGCCGTACGTATCGTTCGCCGCGCCGCTGATGCGCAACGGCGCGGCGACCGGCGCGCTGAGCGGCGCGGTGC
CGCTGGACGGCGTGCGCGAAGTGGTGGCGGCGGTGCATCCGACGCCGTCGAGCCTGGCCTTCGTGGTGGCGCGCGACGGC
CAGGTGATCGCGCACCCCGATGCCAAGCTGATGCTCAAGCCGGTGACGGAGGTGTCGGCCGCGCTGACGCCGGATGCGCT
GACGTCGCTGGCCAAGGCGACCGCGCCGCTGGAAGTGGAGCTGGCCGGTGCCGCCAAGCTGCTCAAGGCGCAGGCGGTGC
AGGGCACCGACTGGTATCTGGTGATCGCGCTGGACAAGGCTGAGGCCACCGCCGGCCTGCGCAGCGTGGCGCGCGCGCTG
GGGGTGGCGATGGTGCTGCTGACGCTGGCGGCGGTAGGCATCGCGGCGTTCTTCACCGCGCAGTCGTTCCGCCGGCTGTC
GCAGGTGCGCGATGCGATGGACACCATCGGCTCCGGCGGCGGCGACCTGACGCATCGGCTGCCGGTGGTCGGCAACGATG
AGGTGGCGCAGATCTCCGCATCGTTCAACACCTTCATCGACAAGATCGGCGAGGTGCTGCTGGAGGTGCGCGCCAGCGTC
GAAAACATGAAGTCCGCCACCGGCGAGATCGAGATGGGCAACCGCGACCTGTCGCTGCGCACGGAGACGTCGGCGAGCAA
CCTGCAGGAAACCTCGGCCGCACTCACCGAGCTGACCACCAGCGTGAAGAACTCCGCCGAGGCCGCAGTGCAGGCCACGC
GCCTCGCGGGCGAGGCCAGCGAGGCGGCCGTGCGCGGCGGCGAGGTGGTGTCGGGTGCGGTCAGCACGATGGACGCGATC
GCGCAGTCGTCGTCGCGCATCAGCGAGATCATCGGCGTGATCGACAGCATTGCGTTCCAGACCAACATCCTCGCGCTCAA
CGCCGCGGTGGAGGCCGCCCGCGCTGGCGAGAACGGCCGCGGCTTTGCCGTGGTGGCCGGCGAGGTGCGCACGCTGGCGC
AGCGCAGCGCCGCCGCCGCGCGCGAGATCAAGGCGCTCATCCAGGCCTCGGAAGCCAGCGTCAAGGCCGGCGCCGAGCGC
GTCGATGCCGCTGGCGCGACGATGCGCGAGATCGTGGAAGGCATCCAGCGCGTCAGCCGCATCATCGGTGAGATCGACGG
CGCCATGCACGAGCAGAGCGCGGGCATCAGCCAGATCGATCGCAGCGTCGCCGAGATGGATCAGGCCACGCAGCAGAACG
CCGCGCTGGTGGAGCAATCGACCGCTGCCTCGTCGATGCTCAACGAGCAGGCGCATGGGCTGGCGCGCACGGTTGGGCTG
TTCCGGCTGCGCGGGGGCTAG

Upstream 100 bases:

>100_bases
ATTCACGCCGTCGTGCCCTGTTCTTTGCTGACTTGATGAGCCCGGGCATGCGAACAACGCTGGGCCAGGCCATCTGCCCC
TCGCATGGGTGGGGGGCCAA

Downstream 100 bases:

>100_bases
CGCCAGACCACGTCGGTCACCTGCGGAATGGTCGGCACCAGCGCCCGCAGGTGCACCTCCAGGCGGCCGGCTTCCGTGTC
GACATCCACGCGGTGGAACA

Product: methyl-accepting chemotaxis transmembrane protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 646; Mature: 646

Protein sequence:

>646_residues
MRESSQVPRSPAVAFSTCAFRPAVAGVRCRHRGTQSDSSPTSKKRITMSSLRTRILVISSATVIGALALSGAATYAIVRA
STLASIDQNLTAIASGNTLAIDKWVTAKAQAVKATAEAVEYGDPHGLVKHMGDADGFPITTVGWTDKTFFSTSAGTPKDY
DPTARPWYKSAIAAGKPTVTKPYGDASTGVPYVSFAAPLMRNGAATGALSGAVPLDGVREVVAAVHPTPSSLAFVVARDG
QVIAHPDAKLMLKPVTEVSAALTPDALTSLAKATAPLEVELAGAAKLLKAQAVQGTDWYLVIALDKAEATAGLRSVARAL
GVAMVLLTLAAVGIAAFFTAQSFRRLSQVRDAMDTIGSGGGDLTHRLPVVGNDEVAQISASFNTFIDKIGEVLLEVRASV
ENMKSATGEIEMGNRDLSLRTETSASNLQETSAALTELTTSVKNSAEAAVQATRLAGEASEAAVRGGEVVSGAVSTMDAI
AQSSSRISEIIGVIDSIAFQTNILALNAAVEAARAGENGRGFAVVAGEVRTLAQRSAAAAREIKALIQASEASVKAGAER
VDAAGATMREIVEGIQRVSRIIGEIDGAMHEQSAGISQIDRSVAEMDQATQQNAALVEQSTAASSMLNEQAHGLARTVGL
FRLRGG

Sequences:

>Translated_646_residues
MRESSQVPRSPAVAFSTCAFRPAVAGVRCRHRGTQSDSSPTSKKRITMSSLRTRILVISSATVIGALALSGAATYAIVRA
STLASIDQNLTAIASGNTLAIDKWVTAKAQAVKATAEAVEYGDPHGLVKHMGDADGFPITTVGWTDKTFFSTSAGTPKDY
DPTARPWYKSAIAAGKPTVTKPYGDASTGVPYVSFAAPLMRNGAATGALSGAVPLDGVREVVAAVHPTPSSLAFVVARDG
QVIAHPDAKLMLKPVTEVSAALTPDALTSLAKATAPLEVELAGAAKLLKAQAVQGTDWYLVIALDKAEATAGLRSVARAL
GVAMVLLTLAAVGIAAFFTAQSFRRLSQVRDAMDTIGSGGGDLTHRLPVVGNDEVAQISASFNTFIDKIGEVLLEVRASV
ENMKSATGEIEMGNRDLSLRTETSASNLQETSAALTELTTSVKNSAEAAVQATRLAGEASEAAVRGGEVVSGAVSTMDAI
AQSSSRISEIIGVIDSIAFQTNILALNAAVEAARAGENGRGFAVVAGEVRTLAQRSAAAAREIKALIQASEASVKAGAER
VDAAGATMREIVEGIQRVSRIIGEIDGAMHEQSAGISQIDRSVAEMDQATQQNAALVEQSTAASSMLNEQAHGLARTVGL
FRLRGG
>Mature_646_residues
MRESSQVPRSPAVAFSTCAFRPAVAGVRCRHRGTQSDSSPTSKKRITMSSLRTRILVISSATVIGALALSGAATYAIVRA
STLASIDQNLTAIASGNTLAIDKWVTAKAQAVKATAEAVEYGDPHGLVKHMGDADGFPITTVGWTDKTFFSTSAGTPKDY
DPTARPWYKSAIAAGKPTVTKPYGDASTGVPYVSFAAPLMRNGAATGALSGAVPLDGVREVVAAVHPTPSSLAFVVARDG
QVIAHPDAKLMLKPVTEVSAALTPDALTSLAKATAPLEVELAGAAKLLKAQAVQGTDWYLVIALDKAEATAGLRSVARAL
GVAMVLLTLAAVGIAAFFTAQSFRRLSQVRDAMDTIGSGGGDLTHRLPVVGNDEVAQISASFNTFIDKIGEVLLEVRASV
ENMKSATGEIEMGNRDLSLRTETSASNLQETSAALTELTTSVKNSAEAAVQATRLAGEASEAAVRGGEVVSGAVSTMDAI
AQSSSRISEIIGVIDSIAFQTNILALNAAVEAARAGENGRGFAVVAGEVRTLAQRSAAAAREIKALIQASEASVKAGAER
VDAAGATMREIVEGIQRVSRIIGEIDGAMHEQSAGISQIDRSVAEMDQATQQNAALVEQSTAASSMLNEQAHGLARTVGL
FRLRGG

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=328, Percent_Identity=50.3048780487805, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1787690, Length=284, Percent_Identity=50.3521126760563, Blast_Score=244, Evalue=2e-65,
Organism=Escherichia coli, GI1788195, Length=284, Percent_Identity=52.4647887323944, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI1788194, Length=291, Percent_Identity=48.7972508591065, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI1789453, Length=248, Percent_Identity=44.3548387096774, Blast_Score=197, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 66737; Mature: 66737

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRESSQVPRSPAVAFSTCAFRPAVAGVRCRHRGTQSDSSPTSKKRITMSSLRTRILVISS
CCCCCCCCCCCCHHHHHHHCCHHHHCHHHHCCCCCCCCCCCHHHHHHHHHHCEEEEEEEC
ATVIGALALSGAATYAIVRASTLASIDQNLTAIASGNTLAIDKWVTAKAQAVKATAEAVE
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECHHHHHHHHHHHHHHHHH
YGDPHGLVKHMGDADGFPITTVGWTDKTFFSTSAGTPKDYDPTARPWYKSAIAAGKPTVT
CCCCHHHHHHCCCCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCC
KPYGDASTGVPYVSFAAPLMRNGAATGALSGAVPLDGVREVVAAVHPTPSSLAFVVARDG
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECC
QVIAHPDAKLMLKPVTEVSAALTPDALTSLAKATAPLEVELAGAAKLLKAQAVQGTDWYL
EEEECCCCCEEEHHHHHHHHHCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCCEEE
VIALDKAEATAGLRSVARALGVAMVLLTLAAVGIAAFFTAQSFRRLSQVRDAMDTIGSGG
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GDLTHRLPVVGNDEVAQISASFNTFIDKIGEVLLEVRASVENMKSATGEIEMGNRDLSLR
CCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEE
TETSASNLQETSAALTELTTSVKNSAEAAVQATRLAGEASEAAVRGGEVVSGAVSTMDAI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHH
AQSSSRISEIIGVIDSIAFQTNILALNAAVEAARAGENGRGFAVVAGEVRTLAQRSAAAA
HHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHH
REIKALIQASEASVKAGAERVDAAGATMREIVEGIQRVSRIIGEIDGAMHEQSAGISQID
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RSVAEMDQATQQNAALVEQSTAASSMLNEQAHGLARTVGLFRLRGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MRESSQVPRSPAVAFSTCAFRPAVAGVRCRHRGTQSDSSPTSKKRITMSSLRTRILVISS
CCCCCCCCCCCCHHHHHHHCCHHHHCHHHHCCCCCCCCCCCHHHHHHHHHHCEEEEEEEC
ATVIGALALSGAATYAIVRASTLASIDQNLTAIASGNTLAIDKWVTAKAQAVKATAEAVE
HHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECHHHHHHHHHHHHHHHHH
YGDPHGLVKHMGDADGFPITTVGWTDKTFFSTSAGTPKDYDPTARPWYKSAIAAGKPTVT
CCCCHHHHHHCCCCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCC
KPYGDASTGVPYVSFAAPLMRNGAATGALSGAVPLDGVREVVAAVHPTPSSLAFVVARDG
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECC
QVIAHPDAKLMLKPVTEVSAALTPDALTSLAKATAPLEVELAGAAKLLKAQAVQGTDWYL
EEEECCCCCEEEHHHHHHHHHCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHCCCCCEEE
VIALDKAEATAGLRSVARALGVAMVLLTLAAVGIAAFFTAQSFRRLSQVRDAMDTIGSGG
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GDLTHRLPVVGNDEVAQISASFNTFIDKIGEVLLEVRASVENMKSATGEIEMGNRDLSLR
CCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEE
TETSASNLQETSAALTELTTSVKNSAEAAVQATRLAGEASEAAVRGGEVVSGAVSTMDAI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHH
AQSSSRISEIIGVIDSIAFQTNILALNAAVEAARAGENGRGFAVVAGEVRTLAQRSAAAA
HHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHH
REIKALIQASEASVKAGAERVDAAGATMREIVEGIQRVSRIIGEIDGAMHEQSAGISQID
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RSVAEMDQATQQNAALVEQSTAASSMLNEQAHGLARTVGLFRLRGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]