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The map label for this gene is aroQ1

Identifier: 17547504

GI number: 17547504

Start: 2995991

End: 2996461

Strand: Direct

Name: aroQ1

Synonym: RSc2785

Alternate gene names: 17547504

Gene position: 2995991-2996461 (Clockwise)

Preceding gene: 17547503

Following gene: 17547505

Centisome position: 80.62

GC content: 66.67

Gene sequence:

>471_bases
GTGGCTGACAAACCGATCGCCAAAGCGGCCCACAGCGTGCTGGTCCTGCACGGCCCCAACCTCAATCTGCTGGGAACGCG
CGAGCCGGAAATCTACGGCGCAACCACACTGGCCGACATCAACGCAGCCCTCGCCGAACGCGCGAGCGCGAGCGGCGTGT
CGCTGGCGCATTTCCAGTCGAACCACGAGGGCGCGCTGGTCGACCGCATCCAGGCGGCCAAGAGCGAAGGCATCGCGTTC
ATCATCATCAACCCGGCCGCTTACACGCACACGAGCGTGGCGCTGCGCGATGCGCTCGCCGGGGTGGCGATTCCGTACAT
CGAGGTCCACCTGTCGAACGTGCATCGCCGTGAGCCGTTCCGCCACCATTCGTACCTGGCGGACCAGGCGGTGGGCGTGA
TCTGCGGGCTGGGCTGGCGCGGCTACCTGGCCGCACTGGATTACATCGTGAGTCAACACGGCGGTGGCTGA

Upstream 100 bases:

>100_bases
CGGTGAAAACACCGATTTCCCGACATCTATTCAGCAAAAACTAGACAAAGCATTCTAAGTTGCTGTAAATTGCGCCCAAT
TTCGCCCATCCAGTCAAACC

Downstream 100 bases:

>100_bases
TCTGCCACCACTTTTCCCTTTTATTTCAACCCCTCAATCAACGCAACGAGCCAGCGCCTGGAGCGTGTCCCGCCGAAGAG
CCATTCGCGCGCGACCTTCC

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase 1; Type II DHQase 1

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MADKPIAKAAHSVLVLHGPNLNLLGTREPEIYGATTLADINAALAERASASGVSLAHFQSNHEGALVDRIQAAKSEGIAF
IIINPAAYTHTSVALRDALAGVAIPYIEVHLSNVHRREPFRHHSYLADQAVGVICGLGWRGYLAALDYIVSQHGGG

Sequences:

>Translated_156_residues
MADKPIAKAAHSVLVLHGPNLNLLGTREPEIYGATTLADINAALAERASASGVSLAHFQSNHEGALVDRIQAAKSEGIAF
IIINPAAYTHTSVALRDALAGVAIPYIEVHLSNVHRREPFRHHSYLADQAVGVICGLGWRGYLAALDYIVSQHGGG
>Mature_155_residues
ADKPIAKAAHSVLVLHGPNLNLLGTREPEIYGATTLADINAALAERASASGVSLAHFQSNHEGALVDRIQAAKSEGIAFI
IINPAAYTHTSVALRDALAGVAIPYIEVHLSNVHRREPFRHHSYLADQAVGVICGLGWRGYLAALDYIVSQHGGG

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ1_RALSO (Q8XVP5)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_520906.1
- ProteinModelPortal:   Q8XVP5
- SMR:   Q8XVP5
- GeneID:   1221632
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc2785
- NMPDR:   fig|267608.1.peg.2785
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- ProtClustDB:   PRK05395
- BioCyc:   RSOL267608:RSC2785-MONOMER
- BRENDA:   4.2.1.10
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16521; Mature: 16390

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 32-32 ACT_SITE 110-110 BINDING 84-84 BINDING 90-90 BINDING 97-97 BINDING 121-121

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKPIAKAAHSVLVLHGPNLNLLGTREPEIYGATTLADINAALAERASASGVSLAHFQS
CCCCCHHHHCCEEEEEECCCCCEEECCCCCEECCHHHHHHHHHHHHHCCCCCCEEEEECC
NHEGALVDRIQAAKSEGIAFIIINPAAYTHTSVALRDALAGVAIPYIEVHLSNVHRREPF
CCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCHHEEEEEHHHHHCCCH
RHHSYLADQAVGVICGLGWRGYLAALDYIVSQHGGG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ADKPIAKAAHSVLVLHGPNLNLLGTREPEIYGATTLADINAALAERASASGVSLAHFQS
CCCCHHHHCCEEEEEECCCCCEEECCCCCEECCHHHHHHHHHHHHHCCCCCCEEEEECC
NHEGALVDRIQAAKSEGIAFIIINPAAYTHTSVALRDALAGVAIPYIEVHLSNVHRREPF
CCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCHHEEEEEHHHHHCCCH
RHHSYLADQAVGVICGLGWRGYLAALDYIVSQHGGG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852