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The map label for this gene is pntAb [H]

Identifier: 17547451

GI number: 17547451

Start: 2939834

End: 2940157

Strand: Direct

Name: pntAb [H]

Synonym: RSc2732

Alternate gene names: 17547451

Gene position: 2939834-2940157 (Clockwise)

Preceding gene: 17547450

Following gene: 17547452

Centisome position: 79.1

GC content: 64.81

Gene sequence:

>324_bases
ATGGAGCTGGTCAATCACACGGTGATCAACCTGATCATCTTCGTGCTGGCGATCTACGTCGGCTACCACGTGGTGTGGAC
GGTCACGCCGGCGCTCCATACGCCGCTGATGGCCGTGACCAATGCCATCTCCGCCATCATCATCGTCGGCGCCATGCTCG
CGGCGGGCCTGACGCAGACCGGACTGGGCCGCACCATGGGCGTGGTGGCGGTGGCGCTGGCGGCGGTCAACGTGTTCGGC
GGCTTCCTGGTCACGCAGCGCATGCTCGAGATGTTCAAGAAGAAGGCGCCCAAGGCCGGCAAGAACGGGGAGGCCCAGTC
ATGA

Upstream 100 bases:

>100_bases
ACCGGATCAAGGAAATCAAGGCAGTCTGAGCGCCGGCGGCGCGCCGCGCACCCCGGCCGCCGCCATCGGTACCGACCGGG
ACGTCATCAGGAGGAGCAAC

Downstream 100 bases:

>100_bases
GCATGAACCTCGTCACCCTGCTGTACCTGCTGGCGTCGGTCTGCTTCATCCAGGCGCTCAAGGGCCTGTCGCACCCGGGC
ACTGCGCGACGCGGCAATGT

Product: transmembrane NAD(P) transhydrogenase alpha subunit

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
MELVNHTVINLIIFVLAIYVGYHVVWTVTPALHTPLMAVTNAISAIIIVGAMLAAGLTQTGLGRTMGVVAVALAAVNVFG
GFLVTQRMLEMFKKKAPKAGKNGEAQS

Sequences:

>Translated_107_residues
MELVNHTVINLIIFVLAIYVGYHVVWTVTPALHTPLMAVTNAISAIIIVGAMLAAGLTQTGLGRTMGVVAVALAAVNVFG
GFLVTQRMLEMFKKKAPKAGKNGEAQS
>Mature_107_residues
MELVNHTVINLIIFVLAIYVGYHVVWTVTPALHTPLMAVTNAISAIIIVGAMLAAGLTQTGLGRTMGVVAVALAAVNVFG
GFLVTQRMLEMFKKKAPKAGKNGEAQS

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=83, Percent_Identity=53.0120481927711, Blast_Score=87, Evalue=2e-18,
Organism=Homo sapiens, GI122939153, Length=83, Percent_Identity=53.0120481927711, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787887, Length=85, Percent_Identity=57.6470588235294, Blast_Score=99, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17550456, Length=91, Percent_Identity=51.6483516483517, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 11263; Mature: 11263

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVNHTVINLIIFVLAIYVGYHVVWTVTPALHTPLMAVTNAISAIIIVGAMLAAGLTQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGRTMGVVAVALAAVNVFGGFLVTQRMLEMFKKKAPKAGKNGEAQS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MELVNHTVINLIIFVLAIYVGYHVVWTVTPALHTPLMAVTNAISAIIIVGAMLAAGLTQT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGRTMGVVAVALAAVNVFGGFLVTQRMLEMFKKKAPKAGKNGEAQS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]