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The map label for this gene is tldD [H]

Identifier: 17547378

GI number: 17547378

Start: 2867915

End: 2869375

Strand: Direct

Name: tldD [H]

Synonym: RSc2659

Alternate gene names: 17547378

Gene position: 2867915-2869375 (Clockwise)

Preceding gene: 17547377

Following gene: 17547379

Centisome position: 77.17

GC content: 68.51

Gene sequence:

>1461_bases
ATGAACGCAGGCGACATCGCCATCCAGAATCTCTCCGTCGCGCGCCGTGTGCTGCTCGATCCGTATGGCCTCGACGAGGC
CCAGTTGCAGCGCGCGCTGGCCGACATCTTCACCCACCGCGTCGACTACGCCGACCTCTACTTCCAGTACACCCGCAACG
AGGCCTGGAGCCTCGAGGAAGGCATCGTCAAGTCGGGCAGCTTCAGCATCGACCAGGGCGTTGGCGTGCGCGCGGTCTCT
GGCGAGCGCACCGCCTTCGCCTATTCCGACGACATCAGCCTGCCGGCGCTGATGCAGGCGGCCGCGGCCACCCGCACCAT
CGGCCGCGCGGGCGCCGGGCGCGTCAAGGTGGCCGGCAGCCTGCAGAGCCAGGGCGGTCGCGCACTGTATACCCCCAACG
ACCCGCTCGACTCGATGACGGCATCGGAGAAGGTGGCGCTGCTGGAGCGCATCGAAAAGCTCGCGCGCGCCAAGGACCCG
CGCGTGGTGCAGGTGATGGCGGGTCTAGCCGGCGAGTACGACGTGATGCTGGTCGCACGCAGCGACGGCGTGATCGCCGC
CGACGTGCGGCCGCTGGTGCGGGTCTCGGTCACCGTCATCGCCGAGCAGAACGGGCGCCGCGAGATGGGCAACTCGGGCG
GCGGCGGCCGCTACGCCTACGGCTACTTCACCGACGAGCTGCTGCATCAGTACGTGGACGAAGCCGTCTCCTCCGCGCTG
GTCAACCTGGAAGCCAAGCCGGCGCCGGCCGGCGCCATGACCGTGGTGCTCGGCCCGGGCTGGCCCGGCGTGCTGCTGCA
CGAGGCGATCGGCCACGGGCTGGAGGGCGACTTCAACCGCAAGGGCTCGTCCGCCTTCTCGGGCCGCATGGGCGAACGCG
TGGCGGCCAAGGGCGTGACCGTAGTGGACGACGGCACGCTGCCCAACCGCCGCGGCTCGCTCAACCTCGACGACGAGGGC
AATCCCACGCAGTGCAACACCCTGATCGAAGACGGCATCCTGACCGGCTACATGCAGGACACGCTCAACGCGCGCCTGAT
GAAGATGCCCGTGACCGGCAACGCGCGCCGCGAAAGCTACGCGTCCCTGCCGATGCCGCGCATGACCAACACCTACATGC
TCGGCGGCGACAAGGATCCGCAGGAGATCATTGCCAGCGTCAAGCGCGGCCTCTATGCCGTCAACTTCGGCGGCGGCCAG
GTCGACATCACCAACGGCAAGTTCGTGTTCTCGGCCAGCGAGGCCTACCTGATCGAGGACGGCAAGATCACCACGCCGGT
CAAGGGCGCCACGCTGGTCGGCAACGGCCCTGAATCGCTCAAGGACGTCACCATGATCGGCAACGACATGCGCCTCGATT
CGGGCGTCGGCGTGTGCGGCAAGGAAGGCCAGAGCGTGCCGGTGGGCGTGGGCCAACCGACCCTGCGCATCGAAAACATG
ACGGTGGGCGGCACGGCCTGA

Upstream 100 bases:

>100_bases
CGGCGACATGGACCCGGCGCGCCTGGCGCAGGTCCGCCGCGACCTGCCCGCGCTCAAGCACCGCGTGATGTAGCCCAACC
GAATTCCCCGAGGACCCACC

Downstream 100 bases:

>100_bases
GCCGCCTGGGCAGGATCCTGCCGATGCGGGGCTGCAACGCGAGGCCGAACGGTCACGACTTGCGGCCCCTGTAGAAACCG
GTTATAAAGGCAGTTCGATT

Product: TldD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MNAGDIAIQNLSVARRVLLDPYGLDEAQLQRALADIFTHRVDYADLYFQYTRNEAWSLEEGIVKSGSFSIDQGVGVRAVS
GERTAFAYSDDISLPALMQAAAATRTIGRAGAGRVKVAGSLQSQGGRALYTPNDPLDSMTASEKVALLERIEKLARAKDP
RVVQVMAGLAGEYDVMLVARSDGVIAADVRPLVRVSVTVIAEQNGRREMGNSGGGGRYAYGYFTDELLHQYVDEAVSSAL
VNLEAKPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFSGRMGERVAAKGVTVVDDGTLPNRRGSLNLDDEG
NPTQCNTLIEDGILTGYMQDTLNARLMKMPVTGNARRESYASLPMPRMTNTYMLGGDKDPQEIIASVKRGLYAVNFGGGQ
VDITNGKFVFSASEAYLIEDGKITTPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPVGVGQPTLRIENM
TVGGTA

Sequences:

>Translated_486_residues
MNAGDIAIQNLSVARRVLLDPYGLDEAQLQRALADIFTHRVDYADLYFQYTRNEAWSLEEGIVKSGSFSIDQGVGVRAVS
GERTAFAYSDDISLPALMQAAAATRTIGRAGAGRVKVAGSLQSQGGRALYTPNDPLDSMTASEKVALLERIEKLARAKDP
RVVQVMAGLAGEYDVMLVARSDGVIAADVRPLVRVSVTVIAEQNGRREMGNSGGGGRYAYGYFTDELLHQYVDEAVSSAL
VNLEAKPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFSGRMGERVAAKGVTVVDDGTLPNRRGSLNLDDEG
NPTQCNTLIEDGILTGYMQDTLNARLMKMPVTGNARRESYASLPMPRMTNTYMLGGDKDPQEIIASVKRGLYAVNFGGGQ
VDITNGKFVFSASEAYLIEDGKITTPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPVGVGQPTLRIENM
TVGGTA
>Mature_486_residues
MNAGDIAIQNLSVARRVLLDPYGLDEAQLQRALADIFTHRVDYADLYFQYTRNEAWSLEEGIVKSGSFSIDQGVGVRAVS
GERTAFAYSDDISLPALMQAAAATRTIGRAGAGRVKVAGSLQSQGGRALYTPNDPLDSMTASEKVALLERIEKLARAKDP
RVVQVMAGLAGEYDVMLVARSDGVIAADVRPLVRVSVTVIAEQNGRREMGNSGGGGRYAYGYFTDELLHQYVDEAVSSAL
VNLEAKPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFSGRMGERVAAKGVTVVDDGTLPNRRGSLNLDDEG
NPTQCNTLIEDGILTGYMQDTLNARLMKMPVTGNARRESYASLPMPRMTNTYMLGGDKDPQEIIASVKRGLYAVNFGGGQ
VDITNGKFVFSASEAYLIEDGKITTPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPVGVGQPTLRIENM
TVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=483, Percent_Identity=60.8695652173913, Blast_Score=565, Evalue=1e-162,
Organism=Escherichia coli, GI1790682, Length=425, Percent_Identity=22.3529411764706, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51544; Mature: 51544

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAGDIAIQNLSVARRVLLDPYGLDEAQLQRALADIFTHRVDYADLYFQYTRNEAWSLEE
CCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCHHH
GIVKSGSFSIDQGVGVRAVSGERTAFAYSDDISLPALMQAAAATRTIGRAGAGRVKVAGS
HHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEC
LQSQGGRALYTPNDPLDSMTASEKVALLERIEKLARAKDPRVVQVMAGLAGEYDVMLVAR
HHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCEEEEEEEE
SDGVIAADVRPLVRVSVTVIAEQNGRREMGNSGGGGRYAYGYFTDELLHQYVDEAVSSAL
CCCEEEECCCCEEEEEEEEEECCCCCHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
VNLEAKPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFSGRMGERVAAKGVT
EECCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCHHHHCCCE
VVDDGTLPNRRGSLNLDDEGNPTQCNTLIEDGILTGYMQDTLNARLMKMPVTGNARRESY
EEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCHHHH
ASLPMPRMTNTYMLGGDKDPQEIIASVKRGLYAVNFGGGQVDITNGKFVFSASEAYLIED
HCCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEEEC
GKITTPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPVGVGQPTLRIENM
CEEECCCCCCEEECCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEE
TVGGTA
ECCCCC
>Mature Secondary Structure
MNAGDIAIQNLSVARRVLLDPYGLDEAQLQRALADIFTHRVDYADLYFQYTRNEAWSLEE
CCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCHHH
GIVKSGSFSIDQGVGVRAVSGERTAFAYSDDISLPALMQAAAATRTIGRAGAGRVKVAGS
HHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEC
LQSQGGRALYTPNDPLDSMTASEKVALLERIEKLARAKDPRVVQVMAGLAGEYDVMLVAR
HHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCEEEEEEEE
SDGVIAADVRPLVRVSVTVIAEQNGRREMGNSGGGGRYAYGYFTDELLHQYVDEAVSSAL
CCCEEEECCCCEEEEEEEEEECCCCCHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
VNLEAKPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFSGRMGERVAAKGVT
EECCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCHHHHCCCE
VVDDGTLPNRRGSLNLDDEGNPTQCNTLIEDGILTGYMQDTLNARLMKMPVTGNARRESY
EEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCHHHH
ASLPMPRMTNTYMLGGDKDPQEIIASVKRGLYAVNFGGGQVDITNGKFVFSASEAYLIED
HCCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEEEC
GKITTPVKGATLVGNGPESLKDVTMIGNDMRLDSGVGVCGKEGQSVPVGVGQPTLRIENM
CEEECCCCCCEEECCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEE
TVGGTA
ECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]