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The map label for this gene is hda [H]

Identifier: 17547344

GI number: 17547344

Start: 2828338

End: 2829039

Strand: Direct

Name: hda [H]

Synonym: RSc2625

Alternate gene names: 17547344

Gene position: 2828338-2829039 (Clockwise)

Preceding gene: 17547343

Following gene: 17547345

Centisome position: 76.1

GC content: 70.37

Gene sequence:

>702_bases
ATGGCCCTTCCGCAACAGCTACCGCTCGAGTTCGGCGCGACACCCGCCCCGACCATCGGCAACTTCGTCGCCACCGGCAA
CGAAGAGGCGGTGCTGCGCCTCTCGGGCCTGGTCGCCGAGCTGGCCGTCGGCCGCGCCGCCGACCGCCTGGTCTACCTGT
GGGGCGAATCCGGCAGCGGCCGCAGCCACCTGCTGCACGCTGTCTGCGCGCAGGCGGAGGCCGCCGGCTTCCAGGCGCGC
TACCTGGAAGCGAAGGCACCGCTGGAAGCGTTCGAATACGACCCCGCCATCACCATCTGGGCCATCGACGACGCCGAGCG
GCTGGACGAATGGGCACAGGTGGCGGCGTTCAATCTGGTCAACGAAGTGCGCGCGGATCCGCATGCCGCGCTGATCACCG
CGGGGGCCGCCGCGCCGATGTCGATGCCGCTGCGTGAAGACCTGCGCACCCGGCTGGGGTGGGGCCTGGTCTACTGGCTG
CGCCCGCTGTCCGACGCCGACAAGGTCGAAGCGCTGCTCCAGGCCGCCCGCGAACGCGGCATGCAGCTGTCGGCCGACGT
GCCGCAATGGCTTGTGACGCACTCCTATCGCGACATGCCGAGCCTGATGGCGCTGCTCGAAGCACTCGACACCTACTCGC
TCGCCCGCAAGCGCGCCGTCACCCTGCCGCTGCTGCGCGACATGCTGGCGCTGCTCAAGTGA

Upstream 100 bases:

>100_bases
CCGATCAGCGCCGTGCTGCTGGTCGGCCTGCGGCAGATCCGGCAGCTCTACCTGGGCAGCAAGCTGTACCGCGACTAATC
CGACCATCGACCCACGTTTC

Downstream 100 bases:

>100_bases
GCCGGTCCGGCTCGACCGGAACACAGTTGGGCGCGACGGTGCTCCACATCGGCCGCCGCCCTCGCTACGCGGCCCCTTGC
CGCACCTTCGGGTAAAATCG

Product: DnaA regulatory inactivator Hda

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MALPQQLPLEFGATPAPTIGNFVATGNEEAVLRLSGLVAELAVGRAADRLVYLWGESGSGRSHLLHAVCAQAEAAGFQAR
YLEAKAPLEAFEYDPAITIWAIDDAERLDEWAQVAAFNLVNEVRADPHAALITAGAAAPMSMPLREDLRTRLGWGLVYWL
RPLSDADKVEALLQAARERGMQLSADVPQWLVTHSYRDMPSLMALLEALDTYSLARKRAVTLPLLRDMLALLK

Sequences:

>Translated_233_residues
MALPQQLPLEFGATPAPTIGNFVATGNEEAVLRLSGLVAELAVGRAADRLVYLWGESGSGRSHLLHAVCAQAEAAGFQAR
YLEAKAPLEAFEYDPAITIWAIDDAERLDEWAQVAAFNLVNEVRADPHAALITAGAAAPMSMPLREDLRTRLGWGLVYWL
RPLSDADKVEALLQAARERGMQLSADVPQWLVTHSYRDMPSLMALLEALDTYSLARKRAVTLPLLRDMLALLK
>Mature_232_residues
ALPQQLPLEFGATPAPTIGNFVATGNEEAVLRLSGLVAELAVGRAADRLVYLWGESGSGRSHLLHAVCAQAEAAGFQARY
LEAKAPLEAFEYDPAITIWAIDDAERLDEWAQVAAFNLVNEVRADPHAALITAGAAAPMSMPLREDLRTRLGWGLVYWLR
PLSDADKVEALLQAARERGMQLSADVPQWLVTHSYRDMPSLMALLEALDTYSLARKRAVTLPLLRDMLALLK

Specific function: Mediates the interactions of dnaA with the beta subunit sliding clamp, promoting hydrolysis of dnaA-bound ATP. It is essential for the control of initiation of DNA replication by inhibiting reinitiation of replication [H]

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family. HdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI226510964, Length=241, Percent_Identity=32.3651452282158, Blast_Score=110, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020591
- InterPro:   IPR017788
- InterPro:   IPR013317
- InterPro:   IPR022864 [H]

Pfam domain/function: PF00308 Bac_DnaA [H]

EC number: NA

Molecular weight: Translated: 25472; Mature: 25340

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPQQLPLEFGATPAPTIGNFVATGNEEAVLRLSGLVAELAVGRAADRLVYLWGESGSG
CCCCCCCCHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
RSHLLHAVCAQAEAAGFQARYLEAKAPLEAFEYDPAITIWAIDDAERLDEWAQVAAFNLV
HHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHH
NEVRADPHAALITAGAAAPMSMPLREDLRTRLGWGLVYWLRPLSDADKVEALLQAARERG
HHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
MQLSADVPQWLVTHSYRDMPSLMALLEALDTYSLARKRAVTLPLLRDMLALLK
CEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
ALPQQLPLEFGATPAPTIGNFVATGNEEAVLRLSGLVAELAVGRAADRLVYLWGESGSG
CCCCCCCHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
RSHLLHAVCAQAEAAGFQARYLEAKAPLEAFEYDPAITIWAIDDAERLDEWAQVAAFNLV
HHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHH
NEVRADPHAALITAGAAAPMSMPLREDLRTRLGWGLVYWLRPLSDADKVEALLQAARERG
HHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
MQLSADVPQWLVTHSYRDMPSLMALLEALDTYSLARKRAVTLPLLRDMLALLK
CEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA