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The map label for this gene is dadA2

Identifier: 17546981

GI number: 17546981

Start: 2453602

End: 2454879

Strand: Reverse

Name: dadA2

Synonym: RSc2262

Alternate gene names: 17546981

Gene position: 2454879-2453602 (Counterclockwise)

Preceding gene: 17546984

Following gene: 17546980

Centisome position: 66.06

GC content: 73.32

Gene sequence:

>1278_bases
ATGCAGATCACGGTTGTGGGCGCCGGCATCGTCGGCATCAGTACGGCGTACGCGCTGGCCCAGGAGGGCCATCAGGTCAC
GCTGGTCGAGCGGAACCCGGGCCCGGGTGAGGGCACCAGCTATGCCAACGGCGGGCAGCTCAGCTATAGCTATGTGGCGC
CGCTGGCCGGGCCGGGCGTGCTGTCGCATGTGCCGGGCTGGCTGTTGCGGCGCGATTCGCCGCTGCGGCTCAAGCCATCG
CTGGACCCGGTGCTGCTGCGCTGGGGCCTGCGCTTCATTGCCGCGTGCAACCGCGAACGGGCCGACCGCACCACGCGCGA
GCTGCTGGCGCTGTCGTTCTACAGCCGCGCCCGCATGGAGGCGCTGCGCGCGGCCTCGCCCGATCTGTCCTTCAGCTTTG
CGCGGCGCGGCAAGCTGGTGGTCTACCGTGATGCCGCGGCCTTTGCGTCGGCCCGTGCCCAGGTCGGCTACCAGGCGACG
CTCGGCTGCGAGCAGCATGCGCTGTCGGCCGACGAGACCATCGCCCGGGAGCCCGCGCTGGCTGGCGCGCGCGGTGCGAT
CGTCGGCGCCATCTACACGCCGGATGAAGACGTGGCCGACTGCCACCAGCTCTGCGTCGGCCTGTTCAACCGGCTGTGCG
CCCTGCCCAATGTGGCGCTGCGCTTCAATGCCGGCGCCGAATCGCTGTGGGTGGAGGGCCGGCGCGTGCGCGGCGTGCGC
ACGGCCCATGAGCCGATCACCGCCGATGCCGTGGTGGTGGCTGCCGGCGTGGCCAGTGCCGGACTGCTCGGCCCGTTGCG
CATCGACCCGGGCCTGTATCCGCTCAAGGGCTACAGCATCAGCCTGCCATTGGGCGAGGGCGGGGCGGGCAGCGATGGCG
CACCGGTCGTCAGCGTCACGGACGCGGCGCGCAAGATCGTCTACGCCCGCATCGGCCGCACGCTGCGCGTGGCGGGCATG
GCGGACCTGGTGGGCTGGTCGGACCGGCTCGACCCGCGCCGCGTGCAGACCCTCTACGACGAAACCCGCGCGCTGTTTCC
CGCCGCGCTGCGCGCCAGCGATGCCGGCGCCGATGCCGCGCCGTGGGCGGGCATGCGGCCGGCGACCCCGACCGGCGTGC
CGGTGGTGGGCCCGTCGCCGGTGGACGGCCTGTGGCTCAATGTCGGCCATGGCGCGCTGGGCTTTACACTGGCCATGGGC
AGCGCCGGCCTGCTGGCCGACCTGATCGCGCGGCGCGCGCCGGCGATCGCGGCGGCGCCGTATGCGCTGGCGCGCTAG

Upstream 100 bases:

>100_bases
ATAGCCCCATGACATTGCCTCCAACAACGCAGCATTTGCGCTGACCCATCCACCGTCCGTAATCTGCCGGCAACGCATTC
CCCGATATTCCAGCAAGTTC

Downstream 100 bases:

>100_bases
GCACGCGATCCGTATCGGCCTTTCTTGGTGAAGCAGTCCTGACCCGAACATCCCGAACAGGAGGGGAATCATGAAGACCT
TGCACACGACCCGGCGCACG

Product: D-amino acid dehydrogenase small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MQITVVGAGIVGISTAYALAQEGHQVTLVERNPGPGEGTSYANGGQLSYSYVAPLAGPGVLSHVPGWLLRRDSPLRLKPS
LDPVLLRWGLRFIAACNRERADRTTRELLALSFYSRARMEALRAASPDLSFSFARRGKLVVYRDAAAFASARAQVGYQAT
LGCEQHALSADETIAREPALAGARGAIVGAIYTPDEDVADCHQLCVGLFNRLCALPNVALRFNAGAESLWVEGRRVRGVR
TAHEPITADAVVVAAGVASAGLLGPLRIDPGLYPLKGYSISLPLGEGGAGSDGAPVVSVTDAARKIVYARIGRTLRVAGM
ADLVGWSDRLDPRRVQTLYDETRALFPAALRASDAGADAAPWAGMRPATPTGVPVVGPSPVDGLWLNVGHGALGFTLAMG
SAGLLADLIARRAPAIAAAPYALAR

Sequences:

>Translated_425_residues
MQITVVGAGIVGISTAYALAQEGHQVTLVERNPGPGEGTSYANGGQLSYSYVAPLAGPGVLSHVPGWLLRRDSPLRLKPS
LDPVLLRWGLRFIAACNRERADRTTRELLALSFYSRARMEALRAASPDLSFSFARRGKLVVYRDAAAFASARAQVGYQAT
LGCEQHALSADETIAREPALAGARGAIVGAIYTPDEDVADCHQLCVGLFNRLCALPNVALRFNAGAESLWVEGRRVRGVR
TAHEPITADAVVVAAGVASAGLLGPLRIDPGLYPLKGYSISLPLGEGGAGSDGAPVVSVTDAARKIVYARIGRTLRVAGM
ADLVGWSDRLDPRRVQTLYDETRALFPAALRASDAGADAAPWAGMRPATPTGVPVVGPSPVDGLWLNVGHGALGFTLAMG
SAGLLADLIARRAPAIAAAPYALAR
>Mature_425_residues
MQITVVGAGIVGISTAYALAQEGHQVTLVERNPGPGEGTSYANGGQLSYSYVAPLAGPGVLSHVPGWLLRRDSPLRLKPS
LDPVLLRWGLRFIAACNRERADRTTRELLALSFYSRARMEALRAASPDLSFSFARRGKLVVYRDAAAFASARAQVGYQAT
LGCEQHALSADETIAREPALAGARGAIVGAIYTPDEDVADCHQLCVGLFNRLCALPNVALRFNAGAESLWVEGRRVRGVR
TAHEPITADAVVVAAGVASAGLLGPLRIDPGLYPLKGYSISLPLGEGGAGSDGAPVVSVTDAARKIVYARIGRTLRVAGM
ADLVGWSDRLDPRRVQTLYDETRALFPAALRASDAGADAAPWAGMRPATPTGVPVVGPSPVDGLWLNVGHGALGFTLAMG
SAGLLADLIARRAPAIAAAPYALAR

Specific function: Oxidative deamination of D-amino acids

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787438, Length=425, Percent_Identity=34.8235294117647, Blast_Score=255, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DADA2_RALSO (Q8XX54)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_520383.1
- ProteinModelPortal:   Q8XX54
- GeneID:   1221107
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc2262
- NMPDR:   fig|267608.1.peg.2262
- HOGENOM:   HBG729204
- OMA:   ASLGCEQ
- ProtClustDB:   PRK00711
- BioCyc:   RSOL267608:RSC2262-MONOMER
- BRENDA:   1.4.99.1
- HAMAP:   MF_01202
- InterPro:   IPR023080
- InterPro:   IPR006076

Pfam domain/function: PF01266 DAO

EC number: =1.4.99.1

Molecular weight: Translated: 44455; Mature: 44455

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQITVVGAGIVGISTAYALAQEGHQVTLVERNPGPGEGTSYANGGQLSYSYVAPLAGPGV
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCH
LSHVPGWLLRRDSPLRLKPSLDPVLLRWGLRFIAACNRERADRTTRELLALSFYSRARME
HHHCCCHHEECCCCCEECCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
ALRAASPDLSFSFARRGKLVVYRDAAAFASARAQVGYQATLGCEQHALSADETIAREPAL
HHHHCCCCCCCHHHCCCCEEEEECHHHHHHHHHHCCEEEECCCHHHHCCCCHHHHCCCCC
AGARGAIVGAIYTPDEDVADCHQLCVGLFNRLCALPNVALRFNAGAESLWVEGRRVRGVR
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHEEECCHHCCCEE
TAHEPITADAVVVAAGVASAGLLGPLRIDPGLYPLKGYSISLPLGEGGAGSDGAPVVSVT
CCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCEECCCEEEEECCCCCCCCCCCCEEEEC
DAARKIVYARIGRTLRVAGMADLVGWSDRLDPRRVQTLYDETRALFPAALRASDAGADAA
HHHHHHHHHHHCCEEEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PWAGMRPATPTGVPVVGPSPVDGLWLNVGHGALGFTLAMGSAGLLADLIARRAPAIAAAP
CCCCCCCCCCCCCEECCCCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHCCCCHHCCC
YALAR
HHHCC
>Mature Secondary Structure
MQITVVGAGIVGISTAYALAQEGHQVTLVERNPGPGEGTSYANGGQLSYSYVAPLAGPGV
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCH
LSHVPGWLLRRDSPLRLKPSLDPVLLRWGLRFIAACNRERADRTTRELLALSFYSRARME
HHHCCCHHEECCCCCEECCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
ALRAASPDLSFSFARRGKLVVYRDAAAFASARAQVGYQATLGCEQHALSADETIAREPAL
HHHHCCCCCCCHHHCCCCEEEEECHHHHHHHHHHCCEEEECCCHHHHCCCCHHHHCCCCC
AGARGAIVGAIYTPDEDVADCHQLCVGLFNRLCALPNVALRFNAGAESLWVEGRRVRGVR
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHEEECCHHCCCEE
TAHEPITADAVVVAAGVASAGLLGPLRIDPGLYPLKGYSISLPLGEGGAGSDGAPVVSVT
CCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCEECCCEEEEECCCCCCCCCCCCEEEEC
DAARKIVYARIGRTLRVAGMADLVGWSDRLDPRRVQTLYDETRALFPAALRASDAGADAA
HHHHHHHHHHHCCEEEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PWAGMRPATPTGVPVVGPSPVDGLWLNVGHGALGFTLAMGSAGLLADLIARRAPAIAAAP
CCCCCCCCCCCCCEECCCCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHCCCCHHCCC
YALAR
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852