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The map label for this gene is pcaI [H]

Identifier: 17546973

GI number: 17546973

Start: 2446514

End: 2447203

Strand: Reverse

Name: pcaI [H]

Synonym: RSc2254

Alternate gene names: 17546973

Gene position: 2447203-2446514 (Counterclockwise)

Preceding gene: 17546980

Following gene: 17546972

Centisome position: 65.85

GC content: 68.99

Gene sequence:

>690_bases
GTGATCAACAAGATTTGCCTGTCCGTGGAGGCCGCGCTGGCCGATATCCCGGACGGCGCCACCATCATGATCGGCGGGTT
CGGTACCGCCGGCATGCCCGCTGCGCTCATCGACGGGCTCATCGCCCACGGCGCGCGCGAGCTGACCATCATCAACAACA
ACGCCGGCAACGGCGAGACGGGCCTGGCGGCGCTGCTCAAGGCGCGGCGCGTGCGCAAGATCGTCTGCTCGTTCCCGCGC
CAGTCCGACTCGTACGTGTTCGACGCGCTCTACCGCGCCGGCGAGATCGAGCTGGAGCTCGTGCCGCAGGGCAACCTGGC
CGAGCGCATTCGCGCGGCGGGCGCCGGCATCGGCGGCTTTTTCTGCCCGACCGCCTACGGCACGCAACTGGCCGAAGGCA
AGGAGACGCGCATCATCGACGGCAAGCCCTACGTGTTCGAACTGCCGCTGACCGCCGACTACGCCCTCATCAAGGCCCTG
CGCGGTGATCGCTGGGGCAACCTGGTCTACCGCAAGACCGCGCGCAACTTCGGCCCCGTGATGGCGATGGCGGCCAAGTG
CACCATCGCCGAGGTCGATGCGACCGTCGAGCTGGGCGCGCTGGACCCGGAGCACATCGTCACGCCGGGCATCTTCGTCA
AGCGCATCGTGCCGGTCGGCGCCGCCGCGCAAACCAGGGAGGCCGCATGA

Upstream 100 bases:

>100_bases
AGACTCGCAGGCCGCGATCCGTGGCCTTGCCGACCGGGCAGCCGGCCGGGCGACGCTCCATCGGCGCCCGCCCCGGGGCG
CCCTGGCCGGAGGATGTCAC

Downstream 100 bases:

>100_bases
ACGCCGAAGCCACCGCCAAGATCCAGCGCTGGACGCGCGACCAGATCGCCGCCCGCGTGGCGCGCGACATCCCCGACGGC
TCGGTCGTCAACCTCGGTAT

Product: 3-oxoadipate CoA-transferase subunit A protein

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MINKICLSVEAALADIPDGATIMIGGFGTAGMPAALIDGLIAHGARELTIINNNAGNGETGLAALLKARRVRKIVCSFPR
QSDSYVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGFFCPTAYGTQLAEGKETRIIDGKPYVFELPLTADYALIKAL
RGDRWGNLVYRKTARNFGPVMAMAAKCTIAEVDATVELGALDPEHIVTPGIFVKRIVPVGAAAQTREAA

Sequences:

>Translated_229_residues
MINKICLSVEAALADIPDGATIMIGGFGTAGMPAALIDGLIAHGARELTIINNNAGNGETGLAALLKARRVRKIVCSFPR
QSDSYVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGFFCPTAYGTQLAEGKETRIIDGKPYVFELPLTADYALIKAL
RGDRWGNLVYRKTARNFGPVMAMAAKCTIAEVDATVELGALDPEHIVTPGIFVKRIVPVGAAAQTREAA
>Mature_229_residues
MINKICLSVEAALADIPDGATIMIGGFGTAGMPAALIDGLIAHGARELTIINNNAGNGETGLAALLKARRVRKIVCSFPR
QSDSYVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGFFCPTAYGTQLAEGKETRIIDGKPYVFELPLTADYALIKAL
RGDRWGNLVYRKTARNFGPVMAMAAKCTIAEVDATVELGALDPEHIVTPGIFVKRIVPVGAAAQTREAA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=224, Percent_Identity=42.4107142857143, Blast_Score=191, Evalue=4e-49,
Organism=Homo sapiens, GI11545841, Length=223, Percent_Identity=43.4977578475336, Blast_Score=173, Evalue=1e-43,
Organism=Escherichia coli, GI1788551, Length=215, Percent_Identity=43.7209302325581, Blast_Score=180, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI17531517, Length=237, Percent_Identity=42.1940928270042, Blast_Score=184, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24655794, Length=231, Percent_Identity=41.991341991342, Blast_Score=177, Evalue=7e-45,
Organism=Drosophila melanogaster, GI21358325, Length=231, Percent_Identity=41.991341991342, Blast_Score=177, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 24214; Mature: 24214

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKICLSVEAALADIPDGATIMIGGFGTAGMPAALIDGLIAHGARELTIINNNAGNGET
CCCHHEEHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHH
GLAALLKARRVRKIVCSFPRQSDSYVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGF
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCC
FCPTAYGTQLAEGKETRIIDGKPYVFELPLTADYALIKALRGDRWGNLVYRKTARNFGPV
CCCCHHCCHHCCCCCCEEECCCCEEEECCCCCHHHHHHHHHCCCCCCCEEEHHHHCCCHH
MAMAAKCTIAEVDATVELGALDPEHIVTPGIFVKRIVPVGAAAQTREAA
HHHHHHCEEEECCCEEEECCCCHHHHCCCCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MINKICLSVEAALADIPDGATIMIGGFGTAGMPAALIDGLIAHGARELTIINNNAGNGET
CCCHHEEHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHH
GLAALLKARRVRKIVCSFPRQSDSYVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGF
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCC
FCPTAYGTQLAEGKETRIIDGKPYVFELPLTADYALIKALRGDRWGNLVYRKTARNFGPV
CCCCHHCCHHCCCCCCEEECCCCEEEECCCCCHHHHHHHHHCCCCCCCEEEHHHHCCCHH
MAMAAKCTIAEVDATVELGALDPEHIVTPGIFVKRIVPVGAAAQTREAA
HHHHHHCEEEECCCEEEECCCCHHHHCCCCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]