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The map label for this gene is ccpA [H]

Identifier: 17546509

GI number: 17546509

Start: 1925341

End: 1926423

Strand: Direct

Name: ccpA [H]

Synonym: RSc1790

Alternate gene names: 17546509

Gene position: 1925341-1926423 (Clockwise)

Preceding gene: 17546507

Following gene: 17546510

Centisome position: 51.81

GC content: 73.78

Gene sequence:

>1083_bases
ATGGCGAGCAGCATCAAGGACGTGGCGACGCACGCCGGCATCTCGATTGCCACGGTCTCGCGCGCCGTCAACGCGCCGGA
GCGCGTGAGCCCCGAGACGCTGGCGCGCGTGCAGGCCGCCATGGACGCGCTGCAATACCGCCCGAACGCGCTGGGCCGCC
AGCTGCGCGCCGTGCGCACCGGCCTGGTGGGCGTGGTGCTGCCGTCGCTGGCCAACCCGGTGTTCGCCGAATGTCTGCAG
GGCATCGACGAGGCCGCGGCGGCGAGCGGCCAGCGCGTGATGCTGATGACCACGGCCTACGACCGCGAGCGCGAGGCCCG
CGCCATCGAGACCCTGCTGCAGCAGCGCGTCGACGGCCTGGTCCTGACGGTGGCCGATGCCGCCGCCAACCCCCACCTGG
ATCGCCTGAACGCCGAGCGCGTGCCTTACGTGCTGGTCTACAACGACACGCAGGGACGGCCGCGCATGCCCGCGCGCTGC
AGCGTGACGGTCGACAACCGCGCCGCGGCGCGTGACGCGATCCGCGCGCTGCTGGGGCGGGGGCACCGGCGCATCCGCAT
GCTGACCGGCACGCTGGCCGCTTCCGACCGGGCCGCGCTGCGCCACGCCGGCTATCGCGACGCGCTGGAGGCGGCCGGCA
TCGCCGCGCAGCCGCCGGTCGAGATCGACTTCAACGCGGAAGCCCTGGCGAGCGCCGAGCTGGACCGCCTGCTGGCCGCG
CCGCGGCCCACCGCCGTGTTCTGCAGCAATGACCGGCTGGCCCTGCTGGCCATCGGCGCACTGCGCACGCGCGGCCTGCG
CGTGCCGGAAGACCTCAGCGTGATCGGCTTCGACGGCCTGGCGATGGGCCAGTGGCTGTCGCCGACGCTGGCGACGGTGG
CGCAACCGCACCGGCAGATCGGCATCGATGCGGCCCAGGCGCTGGCCCGGCGCATCGCCGGCGAGACCGTGCCGCCGATC
ACGCTGCCGCACCGCCTGCTGCCCGGCGGCACGCTGGCCGAGGCGCCCGCCACGTCGGCCGATCCAGATTCCGATTCCAC
CGGTTTTTTCCCCACGTCTGATACGCAAGGAGCGTCTCGATGA

Upstream 100 bases:

>100_bases
GTGTTGCGGGCGCGAGCGCGGTGCCGCATCGGCTGTCATCAAAGCTTCACTGCCGGCGCCTACGATGTAAACGTTTACAA
GCCCTGCGGAGGCGCCGGCA

Downstream 100 bases:

>100_bases
AACGTCTGATCCATTGGCTGCGCGCATGCGGCCTCGTTGCCGCCGGCGCCTTGGCCATGGCGGCGCCGCTGCATGCCCAA
CCCGCGGGCCAGCAGGTCGC

Product: transcription regulator protein

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MASSIKDVATHAGISIATVSRAVNAPERVSPETLARVQAAMDALQYRPNALGRQLRAVRTGLVGVVLPSLANPVFAECLQ
GIDEAAAASGQRVMLMTTAYDREREARAIETLLQQRVDGLVLTVADAAANPHLDRLNAERVPYVLVYNDTQGRPRMPARC
SVTVDNRAAARDAIRALLGRGHRRIRMLTGTLAASDRAALRHAGYRDALEAAGIAAQPPVEIDFNAEALASAELDRLLAA
PRPTAVFCSNDRLALLAIGALRTRGLRVPEDLSVIGFDGLAMGQWLSPTLATVAQPHRQIGIDAAQALARRIAGETVPPI
TLPHRLLPGGTLAEAPATSADPDSDSTGFFPTSDTQGASR

Sequences:

>Translated_360_residues
MASSIKDVATHAGISIATVSRAVNAPERVSPETLARVQAAMDALQYRPNALGRQLRAVRTGLVGVVLPSLANPVFAECLQ
GIDEAAAASGQRVMLMTTAYDREREARAIETLLQQRVDGLVLTVADAAANPHLDRLNAERVPYVLVYNDTQGRPRMPARC
SVTVDNRAAARDAIRALLGRGHRRIRMLTGTLAASDRAALRHAGYRDALEAAGIAAQPPVEIDFNAEALASAELDRLLAA
PRPTAVFCSNDRLALLAIGALRTRGLRVPEDLSVIGFDGLAMGQWLSPTLATVAQPHRQIGIDAAQALARRIAGETVPPI
TLPHRLLPGGTLAEAPATSADPDSDSTGFFPTSDTQGASR
>Mature_359_residues
ASSIKDVATHAGISIATVSRAVNAPERVSPETLARVQAAMDALQYRPNALGRQLRAVRTGLVGVVLPSLANPVFAECLQG
IDEAAAASGQRVMLMTTAYDREREARAIETLLQQRVDGLVLTVADAAANPHLDRLNAERVPYVLVYNDTQGRPRMPARCS
VTVDNRAAARDAIRALLGRGHRRIRMLTGTLAASDRAALRHAGYRDALEAAGIAAQPPVEIDFNAEALASAELDRLLAAP
RPTAVFCSNDRLALLAIGALRTRGLRVPEDLSVIGFDGLAMGQWLSPTLATVAQPHRQIGIDAAQALARRIAGETVPPIT
LPHRLLPGGTLAEAPATSADPDSDSTGFFPTSDTQGASR

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=322, Percent_Identity=34.1614906832298, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI48994940, Length=336, Percent_Identity=33.9285714285714, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1790194, Length=319, Percent_Identity=33.2288401253918, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1790715, Length=339, Percent_Identity=31.5634218289086, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1787948, Length=340, Percent_Identity=32.0588235294118, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789202, Length=298, Percent_Identity=33.8926174496644, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1788474, Length=299, Percent_Identity=33.4448160535117, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1789068, Length=335, Percent_Identity=32.5373134328358, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786540, Length=335, Percent_Identity=31.044776119403, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1787580, Length=333, Percent_Identity=28.5285285285285, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787906, Length=338, Percent_Identity=28.9940828402367, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786268, Length=307, Percent_Identity=24.4299674267101, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790689, Length=324, Percent_Identity=24.3827160493827, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38125; Mature: 37994

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSIKDVATHAGISIATVSRAVNAPERVSPETLARVQAAMDALQYRPNALGRQLRAVRT
CCCCHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GLVGVVLPSLANPVFAECLQGIDEAAAASGQRVMLMTTAYDREREARAIETLLQQRVDGL
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCE
VLTVADAAANPHLDRLNAERVPYVLVYNDTQGRPRMPARCSVTVDNRAAARDAIRALLGR
EEEEECCCCCCCHHHCCCCCCCEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHC
GHRRIRMLTGTLAASDRAALRHAGYRDALEAAGIAAQPPVEIDFNAEALASAELDRLLAA
CCCEEEEEEHHHHCCHHHHHHHCCCHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCC
PRPTAVFCSNDRLALLAIGALRTRGLRVPEDLSVIGFDGLAMGQWLSPTLATVAQPHRQI
CCCCEEEECCCCEEEEEEHHHHHCCCCCCCCCCEEECCCHHHCCCCCHHHHHHHHHHHHH
GIDAAQALARRIAGETVPPITLPHRLLPGGTLAEAPATSADPDSDSTGFFPTSDTQGASR
CHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASSIKDVATHAGISIATVSRAVNAPERVSPETLARVQAAMDALQYRPNALGRQLRAVRT
CCCHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GLVGVVLPSLANPVFAECLQGIDEAAAASGQRVMLMTTAYDREREARAIETLLQQRVDGL
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCE
VLTVADAAANPHLDRLNAERVPYVLVYNDTQGRPRMPARCSVTVDNRAAARDAIRALLGR
EEEEECCCCCCCHHHCCCCCCCEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHC
GHRRIRMLTGTLAASDRAALRHAGYRDALEAAGIAAQPPVEIDFNAEALASAELDRLLAA
CCCEEEEEEHHHHCCHHHHHHHCCCHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCC
PRPTAVFCSNDRLALLAIGALRTRGLRVPEDLSVIGFDGLAMGQWLSPTLATVAQPHRQI
CCCCEEEECCCCEEEEEEHHHHHCCCCCCCCCCEEECCCHHHCCCCCHHHHHHHHHHHHH
GIDAAQALARRIAGETVPPITLPHRLLPGGTLAEAPATSADPDSDSTGFFPTSDTQGASR
CHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]