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The map label for this gene is yfhM [H]

Identifier: 17546489

GI number: 17546489

Start: 1897129

End: 1898064

Strand: Direct

Name: yfhM [H]

Synonym: RSc1770

Alternate gene names: 17546489

Gene position: 1897129-1898064 (Clockwise)

Preceding gene: 17546488

Following gene: 17546491

Centisome position: 51.05

GC content: 69.23

Gene sequence:

>936_bases
ATGACCGCTGCCACCGCCACCCCCGTTGCCGCAATCACGCATCCGCAGTTCGCCGACCTGCCCAACGGCACGCGGCTGCA
TTACGCCAGCGCCGGCCGGCGCGGCGCGCCGCTGATGCTGTTCGTGCACGGCTTTCCGGAGTTCTGGTACGCGTGGGAGG
CGCAGCTCGCGGCGTTCGGCGACACGCACTTTGCGGTGGCGCCGGACATGCGCGGCTACAACCTGTCGAGCAAGCCCGCA
GAGGTGGATGCCTACCGGCCCAAGCCGCTGGTGCAGGACCTGGAGCAGTTCATCACCGCACTGGGCTATGACAGCGCCAT
CGTGGTCGCGCACGATTGGGGCGGGGCGATCTGCTGGAACCTGGCGATCCAGCATCCCGAGCGCGTGGCGCGGCTGGTGA
TCGTCAATTCACCGCATCCGTGGGTGTTCGCCAACGCGCTGCTGAGCGACCCGGCGCAGCAGGCCGCGTCGGCCTATATG
AACTGGCTGCGCCAGCCGGGGGTGGAGGACGTGCTGGCCGCCGACGGCTTCGACAAGCTCGAAGGCTTTTTCAATGGCAT
GGGCCAGCCGGTGGCCGAGTGGTTCACCCCCGACGTGCGCGCGCGCTACCACGCCGCCTGGAGCCGGCCGGGCGAGGGCG
GCTCGCACGGGCTGACCGGCGGGATCAACTACTACCGGGCTTCGCCGCTGCACCCGCCCGCCGAAGGCCAGGCACCGGTG
CGCATCGACCAGATGCCGCCCGAAGCCTTTGTCGTGAAGGTGCCGACGCTCGTGATCTGGGGCGAGAAGGACATGGCGCT
GCCGGCCGCGCTCCTCAACGGGCTGGAGCGCTTCATTCCCGACCTGCGCATCGAGCGCATTCCCAACGGCACGCACTGGG
TGGTGCATGAGCAGCCGGAGCGCATCACGGCGCTGATCCGGCCGTTCGTGGAATAG

Upstream 100 bases:

>100_bases
GTTCGAGGGCAAGCCGGACGTGCGGGCGCGTCTGGTCGAGTCGCTGCGCGGCTGACCGGACACGCCGCCTGCCGACGCCC
CCCGAAACCTGGAGATCGAT

Downstream 100 bases:

>100_bases
CCGTCGCCGGCTACATCGACTCCGCCAGCATCCGGCGGTAATCGTCCGCCGTGGCCTCGCGCGGATTGGTCTTGTGGCAG
TGGTCGAGCAGGGCGCCACG

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTAATATPVAAITHPQFADLPNGTRLHYASAGRRGAPLMLFVHGFPEFWYAWEAQLAAFGDTHFAVAPDMRGYNLSSKPA
EVDAYRPKPLVQDLEQFITALGYDSAIVVAHDWGGAICWNLAIQHPERVARLVIVNSPHPWVFANALLSDPAQQAASAYM
NWLRQPGVEDVLAADGFDKLEGFFNGMGQPVAEWFTPDVRARYHAAWSRPGEGGSHGLTGGINYYRASPLHPPAEGQAPV
RIDQMPPEAFVVKVPTLVIWGEKDMALPAALLNGLERFIPDLRIERIPNGTHWVVHEQPERITALIRPFVE

Sequences:

>Translated_311_residues
MTAATATPVAAITHPQFADLPNGTRLHYASAGRRGAPLMLFVHGFPEFWYAWEAQLAAFGDTHFAVAPDMRGYNLSSKPA
EVDAYRPKPLVQDLEQFITALGYDSAIVVAHDWGGAICWNLAIQHPERVARLVIVNSPHPWVFANALLSDPAQQAASAYM
NWLRQPGVEDVLAADGFDKLEGFFNGMGQPVAEWFTPDVRARYHAAWSRPGEGGSHGLTGGINYYRASPLHPPAEGQAPV
RIDQMPPEAFVVKVPTLVIWGEKDMALPAALLNGLERFIPDLRIERIPNGTHWVVHEQPERITALIRPFVE
>Mature_310_residues
TAATATPVAAITHPQFADLPNGTRLHYASAGRRGAPLMLFVHGFPEFWYAWEAQLAAFGDTHFAVAPDMRGYNLSSKPAE
VDAYRPKPLVQDLEQFITALGYDSAIVVAHDWGGAICWNLAIQHPERVARLVIVNSPHPWVFANALLSDPAQQAASAYMN
WLRQPGVEDVLAADGFDKLEGFFNGMGQPVAEWFTPDVRARYHAAWSRPGEGGSHGLTGGINYYRASPLHPPAEGQAPVR
IDQMPPEAFVVKVPTLVIWGEKDMALPAALLNGLERFIPDLRIERIPNGTHWVVHEQPERITALIRPFVE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=305, Percent_Identity=33.1147540983607, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI218777840, Length=295, Percent_Identity=34.9152542372881, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI13376164, Length=295, Percent_Identity=34.9152542372881, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI27597073, Length=309, Percent_Identity=25.5663430420712, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17554012, Length=294, Percent_Identity=37.0748299319728, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17562298, Length=298, Percent_Identity=32.5503355704698, Blast_Score=174, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 34295; Mature: 34164

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAATATPVAAITHPQFADLPNGTRLHYASAGRRGAPLMLFVHGFPEFWYAWEAQLAAFG
CCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHCC
DTHFAVAPDMRGYNLSSKPAEVDAYRPKPLVQDLEQFITALGYDSAIVVAHDWGGAICWN
CCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEH
LAIQHPERVARLVIVNSPHPWVFANALLSDPAQQAASAYMNWLRQPGVEDVLAADGFDKL
HHHCCCCCEEEEEEEECCCCCEEHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHH
EGFFNGMGQPVAEWFTPDVRARYHAAWSRPGEGGSHGLTGGINYYRASPLHPPAEGQAPV
HHHHCCCCCHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCE
RIDQMPPEAFVVKVPTLVIWGEKDMALPAALLNGLERFIPDLRIERIPNGTHWVVHEQPE
EECCCCCCEEEEEECEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCHH
RITALIRPFVE
HHHHHHHHHCC
>Mature Secondary Structure 
TAATATPVAAITHPQFADLPNGTRLHYASAGRRGAPLMLFVHGFPEFWYAWEAQLAAFG
CCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHCC
DTHFAVAPDMRGYNLSSKPAEVDAYRPKPLVQDLEQFITALGYDSAIVVAHDWGGAICWN
CCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEH
LAIQHPERVARLVIVNSPHPWVFANALLSDPAQQAASAYMNWLRQPGVEDVLAADGFDKL
HHHCCCCCEEEEEEEECCCCCEEHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHH
EGFFNGMGQPVAEWFTPDVRARYHAAWSRPGEGGSHGLTGGINYYRASPLHPPAEGQAPV
HHHHCCCCCHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCE
RIDQMPPEAFVVKVPTLVIWGEKDMALPAALLNGLERFIPDLRIERIPNGTHWVVHEQPE
EECCCCCCEEEEEECEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCHH
RITALIRPFVE
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]