BacMap

Definition	Ralstonia solanacearum GMI1000, complete genome.
Accession	NC_003295
Length	3,716,413

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The map label for this gene is phbB [H]

Identifier: 17546352

GI number: 17546352

Start: 1754514

End: 1755254

Strand: Direct

Name: phbB [H]

Synonym: RSc1633

Alternate gene names: 17546352

Gene position: 1754514-1755254 (Clockwise)

Preceding gene: 17546351

Following gene: 17546353

Centisome position: 47.21

GC content: 63.97

Gene sequence:

>741_bases
ATGACCAAACGCATCGCATACGTCACCGGCGGCATGGGCGGGATCGGTACGGCGATTTGCCAGCGCTTGGCGCGCGACGA
TTTCATCGTCGTCGCGGGGTGCGGCCCGAATTCTCCGCGCAAGGACAAATGGCTCGAGCAGCAGCGCGAGCTGGGCTTCG
ATTTCATCGCCTCGGAAGGCAACGTCGCGGACTGGGATTCGAGCAAGGCTGCGTTCGACAAGGTCAAGGCCGAAGTCGGC
GAGGTCGATGTGCTGATCAACAATGCCGGCATCACCCGCGACGTGGTGTTCCGCAAGATGACCCGGTCGGACTGGGACGC
GGTGATCGGCACCAACCTGACGTCGCTGTTCAACGTGACCAAGCAGGTGATCGACGGCATGGTCGACCGGGGCTGGGGCC
GCATCGTCAACATCTCGTCGGTGAACGGCCAGAAGGGCCAGTTCGGCCAGACCAACTACTCCACCGCCAAGGCCGGCCTG
CACGGCTTCACCATGGCGCTGGCGCAGGAGGTGGCGACCAAGGGGGTGACGGTCAACACCGTGTCGCCGGGCTATATCGC
CACCGACATGGTGAAGGCGATCCGGCAGGACGTGCTCGACAAGATCATCGGCACGATTCCGGTCAAGCGCCTGGGCGATC
CGAATGAGATCGCCTCGATCTGCGCCTGGCTGGCTTCCGAGGAATCCGGCTTCTCGACCGGCGCGGACTTTTCGCTCAAC
GGCGGCCTGCACATGGGCTGA

Upstream 100 bases:

>100_bases
CACGCGGTGGAATGAGCCCGCCGCGCGCCGGCCCCAGACACTGAAGCACCGCCATCCGGCAAGCACCGGGCGGCGCCAAC
AACAACGATCAGGAGCAGAC

Downstream 100 bases:

>100_bases
CCGCCCGCACCCATGCTGCGGCGATGCTGCAGCATGGGTGCAGCAATTTTTCCCGTTTTTTCCCTCCGGTGCTGCTCCGC
TTGGATGCGCCGCAGCAGGG

Product: acetyacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTKRIAYVTGGMGGIGTAICQRLARDDFIVVAGCGPNSPRKDKWLEQQRELGFDFIASEGNVADWDSSKAAFDKVKAEVG
EVDVLINNAGITRDVVFRKMTRSDWDAVIGTNLTSLFNVTKQVIDGMVDRGWGRIVNISSVNGQKGQFGQTNYSTAKAGL
HGFTMALAQEVATKGVTVNTVSPGYIATDMVKAIRQDVLDKIIGTIPVKRLGDPNEIASICAWLASEESGFSTGADFSLN
GGLHMG

Sequences:

>Translated_246_residues
MTKRIAYVTGGMGGIGTAICQRLARDDFIVVAGCGPNSPRKDKWLEQQRELGFDFIASEGNVADWDSSKAAFDKVKAEVG
EVDVLINNAGITRDVVFRKMTRSDWDAVIGTNLTSLFNVTKQVIDGMVDRGWGRIVNISSVNGQKGQFGQTNYSTAKAGL
HGFTMALAQEVATKGVTVNTVSPGYIATDMVKAIRQDVLDKIIGTIPVKRLGDPNEIASICAWLASEESGFSTGADFSLN
GGLHMG
>Mature_245_residues
TKRIAYVTGGMGGIGTAICQRLARDDFIVVAGCGPNSPRKDKWLEQQRELGFDFIASEGNVADWDSSKAAFDKVKAEVGE
VDVLINNAGITRDVVFRKMTRSDWDAVIGTNLTSLFNVTKQVIDGMVDRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLH
GFTMALAQEVATKGVTVNTVSPGYIATDMVKAIRQDVLDKIIGTIPVKRLGDPNEIASICAWLASEESGFSTGADFSLNG
GLHMG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=37.5494071146245, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=34.2741935483871, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI4504505, Length=246, Percent_Identity=31.3008130081301, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=30.7086614173228, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=29.6, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI7705855, Length=202, Percent_Identity=33.1683168316832, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=29.1338582677165, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI19923817, Length=248, Percent_Identity=29.4354838709677, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI7705925, Length=186, Percent_Identity=27.9569892473118, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI66933014, Length=183, Percent_Identity=29.5081967213115, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=27.710843373494, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=27.710843373494, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=27.4509803921569, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=246, Percent_Identity=28.4552845528455, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=29.6116504854369, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI109715829, Length=239, Percent_Identity=24.2677824267782, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI59889578, Length=216, Percent_Identity=28.7037037037037, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4503817, Length=185, Percent_Identity=28.6486486486486, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI7706318, Length=213, Percent_Identity=25.8215962441315, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI22507405, Length=194, Percent_Identity=28.3505154639175, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI150247226, Length=189, Percent_Identity=30.1587301587302, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI226371731, Length=223, Percent_Identity=26.0089686098655, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI7657478, Length=209, Percent_Identity=27.7511961722488, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI40548397, Length=201, Percent_Identity=27.8606965174129, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI214010158, Length=201, Percent_Identity=27.8606965174129, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI214010156, Length=201, Percent_Identity=27.8606965174129, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI22758144, Length=201, Percent_Identity=27.8606965174129, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=41.5322580645161, Blast_Score=190, Evalue=7e-50,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=36.3636363636364, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1790717, Length=238, Percent_Identity=29.4117647058824, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=30.6122448979592, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=30.0411522633745, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788459, Length=177, Percent_Identity=33.8983050847458, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=29.0983606557377, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=30.8943089430894, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=26.8, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=26.4, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=27.0833333333333, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=28.9617486338798, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=25.78125, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786701, Length=200, Percent_Identity=29, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=40.080971659919, Blast_Score=160, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=37.0967741935484, Blast_Score=148, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=29.5546558704453, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17568967, Length=248, Percent_Identity=33.4677419354839, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=31.1740890688259, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=30, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=29.1338582677165, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=29.2490118577075, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=28.2786885245902, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=28.030303030303, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=155, Percent_Identity=33.5483870967742, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=28.7878787878788, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=155, Percent_Identity=33.5483870967742, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=27.1375464684015, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=196, Percent_Identity=27.5510204081633, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=251, Percent_Identity=28.6852589641434, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=27.2, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=27.2, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=27.9850746268657, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=185, Percent_Identity=31.8918918918919, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=27.1375464684015, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=256, Percent_Identity=28.125, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=26.3779527559055, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=27.9850746268657, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=257, Percent_Identity=26.8482490272374, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=27.5862068965517, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=252, Percent_Identity=28.1746031746032, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=184, Percent_Identity=27.1739130434783, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=24.2424242424242, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322861, Length=252, Percent_Identity=32.5396825396825, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=24.3137254901961, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322227, Length=256, Percent_Identity=25, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=201, Percent_Identity=25.8706467661692, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=35.0597609561753, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=33.201581027668, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=31.640625, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=30.1587301587302, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=31.640625, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=29.1497975708502, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=30.2325581395349, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=28.7449392712551, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI18859837, Length=232, Percent_Identity=31.8965517241379, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24644337, Length=169, Percent_Identity=33.7278106508876, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21358495, Length=199, Percent_Identity=31.1557788944724, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641232, Length=217, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=28.4210526315789, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=28.4210526315789, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI116007236, Length=203, Percent_Identity=31.5270935960591, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24640442, Length=203, Percent_Identity=29.064039408867, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28574402, Length=195, Percent_Identity=26.1538461538462, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24584744, Length=195, Percent_Identity=26.1538461538462, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24581726, Length=157, Percent_Identity=27.3885350318471, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 26354; Mature: 26223

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRIAYVTGGMGGIGTAICQRLARDDFIVVAGCGPNSPRKDKWLEQQRELGFDFIASEG
CCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCC
NVADWDSSKAAFDKVKAEVGEVDVLINNAGITRDVVFRKMTRSDWDAVIGTNLTSLFNVT
CCCCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KQVIDGMVDRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNT
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEC
VSPGYIATDMVKAIRQDVLDKIIGTIPVKRLGDPNEIASICAWLASEESGFSTGADFSLN
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEC
GGLHMG
CCCCCC
>Mature Secondary Structure 
TKRIAYVTGGMGGIGTAICQRLARDDFIVVAGCGPNSPRKDKWLEQQRELGFDFIASEG
CCEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCC
NVADWDSSKAAFDKVKAEVGEVDVLINNAGITRDVVFRKMTRSDWDAVIGTNLTSLFNVT
CCCCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KQVIDGMVDRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNT
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEC
VSPGYIATDMVKAIRQDVLDKIIGTIPVKRLGDPNEIASICAWLASEESGFSTGADFSLN
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEC
GGLHMG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2670935 [H]