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The map label for this gene is codA [H]

Identifier: 17546313

GI number: 17546313

Start: 1709193

End: 1710464

Strand: Direct

Name: codA [H]

Synonym: RSc1594

Alternate gene names: 17546313

Gene position: 1709193-1710464 (Clockwise)

Preceding gene: 17546310

Following gene: 17546319

Centisome position: 45.99

GC content: 70.6

Gene sequence:

>1272_bases
ATGGATTTCGTGATTCGCAATGCGAGCCTGCCCGACGGGCGCGCCGGTATCGACATCGGCATCGCAGCGGGCCGTATCGA
GGCGGTGCAGCAGCGCCTGCCGGCACGCGGCGCGGAGGAGGTCGATGCCGCCGGCGCACTGGTGTCGCCGCCGTTCGTCG
ATGCGCATTTCCACATGGATGCGACGCTGTCATACGGGCTGCCGCGCGTGAACCGGTCCGGCACGCTGCTCGAAGGCATC
GCGCTGTGGGGCGAGCTCAAGCCCGCGCTGACGCAGGAGGCGCTGATCGAGCGTGCGCTGCGCTACTGCGACTGGGCGGT
CGCGCGCGGCCTGCTGGCGATCCGCTCGCACGTGGACGTGTGCGATGCGCGCCTGCTGGCGGTCGAGGCGCTGCTGCACG
TCAAGCGGCAGGTGGCGCCTTACCTCGACCTGCAGCTCGTGGCCTTCCCGCCGGACGGCGTGCTGCGCAGTCCGGGCGCC
TTCGACAACCTCAGGCGCGCCATCGGCATGGGCGTCGATGTGGTCGGCGGCATTCCGCATTTCGAGCGCACCATGGCCGA
CGGCGCGGAATCGGTGCGGCTGCTGTGCGAGTTCGCCGCCGAGCGCGGCCTGCGCGTCGACATGCATTGCGACGAGTCGG
ACGATCCGCTGTCGCGCCATGTCGAGACGCTCGCGGCGCAGGCGCACCGCCTCGGCCTGCACGGCCGCGTGGCCGGCTCG
CACCTGACCTCGATGCACTCGATGGACAACTACTACGTCAGCAAGCTGCTTCCGCTGATGCGCGAGGCCGGCGTCGCGGC
GATCGCCAATCCGCTGATCAACATCACGCTGCAGGGCCGCTCGGACACCTATCCGAAGCGGCGCGGCATGACCCGCGTGC
CGGAACTGCTGGCCGCCGGCATCGACGTCGCCTTCGGCCATGACTGCGTGATGGACCCGTGGTACGGCCTGGGCTCGGGC
GACATGCTGGAAGTGGCCCACATGGGTTTGCACGTGGCCCAGATGACCGGCCAGGCGGCGATGCGCCAGTGCTTTGCCGC
CGTGACCGAAACGCCCGCGCGCATCCTCGGCCTGGAAGGCTACGGCATCGCGCCGGGCTGCCATGCCGATCTGGTGATGC
TCGATGCGCGAGATCCGATCGAGGCAATCCGCCTGCGCGCGGCGCGCACGCTGGTGATGCGGCGGGGCCGGGTGGTGGCG
CGCACGCCCGCGCCGCATGCCGTGCTGTCGCTGCCGGGGCGAGCACCACGCGTCGATTTTCGGCTCGCCTGA

Upstream 100 bases:

>100_bases
CGCCCGGATGGAGCGCTATTGTGCCACCAAGCCTCCGCCCGGCATCCGACGGCGTCCCGCATGCGGTAGATTGATGAGAA
TCGACCGCACGGGAGCATCC

Downstream 100 bases:

>100_bases
AAGACAAACGCCGCTTCGGCGCGGGGCGCGAAGCGGCGTGCTGTGCGGCGGTCAGCCGGCCCAGGCTCAGGCGGGTTCGG
CCGTCACCACCATGCCGCCA

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MDFVIRNASLPDGRAGIDIGIAAGRIEAVQQRLPARGAEEVDAAGALVSPPFVDAHFHMDATLSYGLPRVNRSGTLLEGI
ALWGELKPALTQEALIERALRYCDWAVARGLLAIRSHVDVCDARLLAVEALLHVKRQVAPYLDLQLVAFPPDGVLRSPGA
FDNLRRAIGMGVDVVGGIPHFERTMADGAESVRLLCEFAAERGLRVDMHCDESDDPLSRHVETLAAQAHRLGLHGRVAGS
HLTSMHSMDNYYVSKLLPLMREAGVAAIANPLINITLQGRSDTYPKRRGMTRVPELLAAGIDVAFGHDCVMDPWYGLGSG
DMLEVAHMGLHVAQMTGQAAMRQCFAAVTETPARILGLEGYGIAPGCHADLVMLDARDPIEAIRLRAARTLVMRRGRVVA
RTPAPHAVLSLPGRAPRVDFRLA

Sequences:

>Translated_423_residues
MDFVIRNASLPDGRAGIDIGIAAGRIEAVQQRLPARGAEEVDAAGALVSPPFVDAHFHMDATLSYGLPRVNRSGTLLEGI
ALWGELKPALTQEALIERALRYCDWAVARGLLAIRSHVDVCDARLLAVEALLHVKRQVAPYLDLQLVAFPPDGVLRSPGA
FDNLRRAIGMGVDVVGGIPHFERTMADGAESVRLLCEFAAERGLRVDMHCDESDDPLSRHVETLAAQAHRLGLHGRVAGS
HLTSMHSMDNYYVSKLLPLMREAGVAAIANPLINITLQGRSDTYPKRRGMTRVPELLAAGIDVAFGHDCVMDPWYGLGSG
DMLEVAHMGLHVAQMTGQAAMRQCFAAVTETPARILGLEGYGIAPGCHADLVMLDARDPIEAIRLRAARTLVMRRGRVVA
RTPAPHAVLSLPGRAPRVDFRLA
>Mature_423_residues
MDFVIRNASLPDGRAGIDIGIAAGRIEAVQQRLPARGAEEVDAAGALVSPPFVDAHFHMDATLSYGLPRVNRSGTLLEGI
ALWGELKPALTQEALIERALRYCDWAVARGLLAIRSHVDVCDARLLAVEALLHVKRQVAPYLDLQLVAFPPDGVLRSPGA
FDNLRRAIGMGVDVVGGIPHFERTMADGAESVRLLCEFAAERGLRVDMHCDESDDPLSRHVETLAAQAHRLGLHGRVAGS
HLTSMHSMDNYYVSKLLPLMREAGVAAIANPLINITLQGRSDTYPKRRGMTRVPELLAAGIDVAFGHDCVMDPWYGLGSG
DMLEVAHMGLHVAQMTGQAAMRQCFAAVTETPARILGLEGYGIAPGCHADLVMLDARDPIEAIRLRAARTLVMRRGRVVA
RTPAPHAVLSLPGRAPRVDFRLA

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=420, Percent_Identity=44.2857142857143, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1786517, Length=403, Percent_Identity=27.2952853598015, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 45723; Mature: 45723

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFVIRNASLPDGRAGIDIGIAAGRIEAVQQRLPARGAEEVDAAGALVSPPFVDAHFHMD
CCEEEECCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEEEEEEC
ATLSYGLPRVNRSGTLLEGIALWGELKPALTQEALIERALRYCDWAVARGLLAIRSHVDV
CHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CDARLLAVEALLHVKRQVAPYLDLQLVAFPPDGVLRSPGAFDNLRRAIGMGVDVVGGIPH
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCHHCCCCCH
FERTMADGAESVRLLCEFAAERGLRVDMHCDESDDPLSRHVETLAAQAHRLGLHGRVAGS
HHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
HLTSMHSMDNYYVSKLLPLMREAGVAAIANPLINITLQGRSDTYPKRRGMTRVPELLAAG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHC
IDVAFGHDCVMDPWYGLGSGDMLEVAHMGLHVAQMTGQAAMRQCFAAVTETPARILGLEG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCC
YGIAPGCHADLVMLDARDPIEAIRLRAARTLVMRRGRVVARTPAPHAVLSLPGRAPRVDF
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCCCCCCCE
RLA
EEC
>Mature Secondary Structure
MDFVIRNASLPDGRAGIDIGIAAGRIEAVQQRLPARGAEEVDAAGALVSPPFVDAHFHMD
CCEEEECCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEEEEEEC
ATLSYGLPRVNRSGTLLEGIALWGELKPALTQEALIERALRYCDWAVARGLLAIRSHVDV
CHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CDARLLAVEALLHVKRQVAPYLDLQLVAFPPDGVLRSPGAFDNLRRAIGMGVDVVGGIPH
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCHHCCCCCH
FERTMADGAESVRLLCEFAAERGLRVDMHCDESDDPLSRHVETLAAQAHRLGLHGRVAGS
HHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
HLTSMHSMDNYYVSKLLPLMREAGVAAIANPLINITLQGRSDTYPKRRGMTRVPELLAAG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHC
IDVAFGHDCVMDPWYGLGSGDMLEVAHMGLHVAQMTGQAAMRQCFAAVTETPARILGLEG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCC
YGIAPGCHADLVMLDARDPIEAIRLRAARTLVMRRGRVVARTPAPHAVLSLPGRAPRVDF
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCCCCCCCE
RLA
EEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]