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The map label for this gene is yhdG [H]

Identifier: 17546307

GI number: 17546307

Start: 1703770

End: 1705200

Strand: Direct

Name: yhdG [H]

Synonym: RSc1588

Alternate gene names: 17546307

Gene position: 1703770-1705200 (Clockwise)

Preceding gene: 17546306

Following gene: 17546309

Centisome position: 45.84

GC content: 66.81

Gene sequence:

>1431_bases
ATGAGTTTGTTCCGTACCAAGAACCTGGATCACATGATCCGCACCGGCCAGGGCGATACCGGCCTGAAGAAAGTCTTCGG
ACCGCTGGACCTGACCTTCCTGGGGGTCGGCGCCATCATCGGCACCGGCATCTTCGTGCTGACCGGCACCGGTGCGCTGA
CCGCGGGGCCCGCGCTGACGCTGTCGTTCGTCGTTGCGGCGCTGGCATGCGGGTTTGCGGCGCTGTGCTACGCCGAATTT
GCCTCGACCATTCCCGTGTCGGGCTCGATCTATACCTATGCCTATGCCACGCTGGGTGAACTGGTGGCCTGGATCATCGG
CTGGGACCTGATGCTCGAATACGGCCTGGCGACCTCGGCCGTGTCGGTGGGCTGGTCGGGCTATTTCCAGTCGCTGATGG
CGGGTTTCGGCCTGCATCTGCCGGCGGCGCTGATGGCCGCACCGGGGGCGATTCCGGGCGTGCAGACGCTGTTCAACCTG
CCGGCGCTGCTGATCATGCTGATCATCACGGCGGTGCTGTCGCTCGGCGTGCGCGAGTCGGCGCGGTTCAACAACATCAT
GGTGGCGATCAAGGTGGCGGTGGTGGTGCTGTTCATCGTCGTCGGCGCGCGGCACGTGCAGCCGGCCAACTGGCAGCCGT
TCATGCCGTTCGGCATGTCGGGCGTGTTCGGTGCCGCGGCCCTCGTGTTCTTTGCCTTCATCGGCTTCGACGCGGTGACT
GCCGCCGCGGAGGAGGTGCGCAACCCCGAGCGCGACCTGCCGATCGGCATCATCGGCTCGCTGGGCGTCTGCACGATCCT
CTACGTGGTGGTGGCCGCCATCATGACCGGCATCGTGCCGTACACCAAGTTCGCCGGCGTTGACCACCCGGTGTCGCTGG
CGCTGCAGATGGGCGGCGAGACGTGGGTGGCCGGGTTTGTGGACCTGGGCGCCATCATCGGCATGACGACGGTGATCCTG
GTGATGGGCTATGGGCAGACCCGCGTCATCTTTGCGATGTCGCGCGACGGCCTGCTGCCCAAGCGCCTGTCGCGGGTCCA
CCCGCGCTATGCGACGCCGTTCTTCAATACCTGGCTGGTCGGCATCGTGTTTGCGCTGATCGCCGCCTTTGTGCCGCTGA
ACGTGCTGGCCGAGCTCATTAACATCGGCACGCTGGCCGCGTTTTCGCTGATCGCGATCGCCGTGCTGGTCCTGCGCCGC
AAGCGCCCGGACTTGCCGCGCGGCTTCCGCTGCCCGGGCGTGCCGTTCGTGCCGGCGGCGGCCGTCGTGCTGTGCGTGTT
CCTGATGAGCCAGCTGCAGGCCCTGACCTGGATCGCCTTCGTGGTCTGGATGGTGATCGGCCTGCTGGTGTATTTCGGCT
ATGCGCGCAGCCGGTCGCTGCTGCATGCGCCGGACCGTGCGGCGGTGCCGGGCTCCGAAGCGGCGCACTGA

Upstream 100 bases:

>100_bases
AAATGCCCGCTTTTTTGCATAATCCGCCGCCGCGCGCCACACGTGCGCGACAGCGCATTCCGTCACACTCCGGACATGCG
CGCAGACAGGAGACGCCTTG

Downstream 100 bases:

>100_bases
CCGGGGTGCCGCTTAGCGGCACAGCGGCGCAGCGGTCGCCTGCAGGATTTCCGCGTCGCGGGGCCGCTCTATGAGGGCGG
CCAGTCCCACATCGGCCGGC

Product: amino-acid transporter transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSLFRTKNLDHMIRTGQGDTGLKKVFGPLDLTFLGVGAIIGTGIFVLTGTGALTAGPALTLSFVVAALACGFAALCYAEF
ASTIPVSGSIYTYAYATLGELVAWIIGWDLMLEYGLATSAVSVGWSGYFQSLMAGFGLHLPAALMAAPGAIPGVQTLFNL
PALLIMLIITAVLSLGVRESARFNNIMVAIKVAVVVLFIVVGARHVQPANWQPFMPFGMSGVFGAAALVFFAFIGFDAVT
AAAEEVRNPERDLPIGIIGSLGVCTILYVVVAAIMTGIVPYTKFAGVDHPVSLALQMGGETWVAGFVDLGAIIGMTTVIL
VMGYGQTRVIFAMSRDGLLPKRLSRVHPRYATPFFNTWLVGIVFALIAAFVPLNVLAELINIGTLAAFSLIAIAVLVLRR
KRPDLPRGFRCPGVPFVPAAAVVLCVFLMSQLQALTWIAFVVWMVIGLLVYFGYARSRSLLHAPDRAAVPGSEAAH

Sequences:

>Translated_476_residues
MSLFRTKNLDHMIRTGQGDTGLKKVFGPLDLTFLGVGAIIGTGIFVLTGTGALTAGPALTLSFVVAALACGFAALCYAEF
ASTIPVSGSIYTYAYATLGELVAWIIGWDLMLEYGLATSAVSVGWSGYFQSLMAGFGLHLPAALMAAPGAIPGVQTLFNL
PALLIMLIITAVLSLGVRESARFNNIMVAIKVAVVVLFIVVGARHVQPANWQPFMPFGMSGVFGAAALVFFAFIGFDAVT
AAAEEVRNPERDLPIGIIGSLGVCTILYVVVAAIMTGIVPYTKFAGVDHPVSLALQMGGETWVAGFVDLGAIIGMTTVIL
VMGYGQTRVIFAMSRDGLLPKRLSRVHPRYATPFFNTWLVGIVFALIAAFVPLNVLAELINIGTLAAFSLIAIAVLVLRR
KRPDLPRGFRCPGVPFVPAAAVVLCVFLMSQLQALTWIAFVVWMVIGLLVYFGYARSRSLLHAPDRAAVPGSEAAH
>Mature_475_residues
SLFRTKNLDHMIRTGQGDTGLKKVFGPLDLTFLGVGAIIGTGIFVLTGTGALTAGPALTLSFVVAALACGFAALCYAEFA
STIPVSGSIYTYAYATLGELVAWIIGWDLMLEYGLATSAVSVGWSGYFQSLMAGFGLHLPAALMAAPGAIPGVQTLFNLP
ALLIMLIITAVLSLGVRESARFNNIMVAIKVAVVVLFIVVGARHVQPANWQPFMPFGMSGVFGAAALVFFAFIGFDAVTA
AAEEVRNPERDLPIGIIGSLGVCTILYVVVAAIMTGIVPYTKFAGVDHPVSLALQMGGETWVAGFVDLGAIIGMTTVILV
MGYGQTRVIFAMSRDGLLPKRLSRVHPRYATPFFNTWLVGIVFALIAAFVPLNVLAELINIGTLAAFSLIAIAVLVLRRK
RPDLPRGFRCPGVPFVPAAAVVLCVFLMSQLQALTWIAFVVWMVIGLLVYFGYARSRSLLHAPDRAAVPGSEAAH

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258614003, Length=413, Percent_Identity=36.0774818401937, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI258614005, Length=413, Percent_Identity=36.0774818401937, Blast_Score=229, Evalue=5e-60,
Organism=Homo sapiens, GI4507047, Length=427, Percent_Identity=37.2365339578454, Blast_Score=228, Evalue=7e-60,
Organism=Homo sapiens, GI258645169, Length=413, Percent_Identity=36.0774818401937, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI181337167, Length=421, Percent_Identity=36.5795724465558, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI110347453, Length=392, Percent_Identity=36.734693877551, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI114326544, Length=439, Percent_Identity=33.9407744874715, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI114326550, Length=439, Percent_Identity=33.9407744874715, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI186910308, Length=416, Percent_Identity=27.8846153846154, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI186910306, Length=416, Percent_Identity=27.8846153846154, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI186910304, Length=416, Percent_Identity=27.8846153846154, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI115648063, Length=433, Percent_Identity=26.7898383371824, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI115648022, Length=433, Percent_Identity=26.7898383371824, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI187423910, Length=485, Percent_Identity=25.1546391752577, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI7657591, Length=485, Percent_Identity=25.1546391752577, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI7657683, Length=410, Percent_Identity=27.3170731707317, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI33286428, Length=423, Percent_Identity=27.1867612293144, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI71979932, Length=451, Percent_Identity=28.159645232816, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI9790235, Length=294, Percent_Identity=25.5102040816327, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI87081869, Length=411, Percent_Identity=25.5474452554745, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082023, Length=464, Percent_Identity=25.2155172413793, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788480, Length=450, Percent_Identity=25.7777777777778, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786302, Length=464, Percent_Identity=23.7068965517241, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081915, Length=421, Percent_Identity=23.9904988123515, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87082250, Length=470, Percent_Identity=25.7446808510638, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081708, Length=449, Percent_Identity=23.162583518931, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789017, Length=398, Percent_Identity=24.1206030150754, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786694, Length=394, Percent_Identity=24.3654822335025, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786602, Length=421, Percent_Identity=22.5653206650831, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786789, Length=332, Percent_Identity=23.7951807228916, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790653, Length=416, Percent_Identity=21.6346153846154, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=415, Percent_Identity=36.6265060240964, Blast_Score=245, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI17531343, Length=396, Percent_Identity=33.8383838383838, Blast_Score=207, Evalue=9e-54,
Organism=Caenorhabditis elegans, GI17533459, Length=415, Percent_Identity=31.3253012048193, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17568033, Length=414, Percent_Identity=26.0869565217391, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17540018, Length=415, Percent_Identity=25.5421686746988, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17537453, Length=387, Percent_Identity=22.4806201550388, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193208714, Length=403, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI32566695, Length=403, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71982612, Length=395, Percent_Identity=24.3037974683544, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71982608, Length=395, Percent_Identity=24.3037974683544, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319991, Length=354, Percent_Identity=27.9661016949153, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24668806, Length=423, Percent_Identity=36.1702127659575, Blast_Score=259, Evalue=4e-69,
Organism=Drosophila melanogaster, GI21356285, Length=423, Percent_Identity=36.1702127659575, Blast_Score=259, Evalue=4e-69,
Organism=Drosophila melanogaster, GI24668802, Length=423, Percent_Identity=36.1702127659575, Blast_Score=259, Evalue=4e-69,
Organism=Drosophila melanogaster, GI221512776, Length=421, Percent_Identity=34.916864608076, Blast_Score=251, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24666159, Length=421, Percent_Identity=34.916864608076, Blast_Score=251, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24667468, Length=434, Percent_Identity=33.4101382488479, Blast_Score=244, Evalue=9e-65,
Organism=Drosophila melanogaster, GI161077963, Length=430, Percent_Identity=36.7441860465116, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI281366235, Length=413, Percent_Identity=33.6561743341404, Blast_Score=197, Evalue=9e-51,
Organism=Drosophila melanogaster, GI116007820, Length=413, Percent_Identity=33.6561743341404, Blast_Score=197, Evalue=9e-51,
Organism=Drosophila melanogaster, GI116007818, Length=413, Percent_Identity=33.6561743341404, Blast_Score=195, Evalue=6e-50,
Organism=Drosophila melanogaster, GI85725152, Length=413, Percent_Identity=33.6561743341404, Blast_Score=195, Evalue=6e-50,
Organism=Drosophila melanogaster, GI21357367, Length=437, Percent_Identity=26.0869565217391, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24651635, Length=393, Percent_Identity=26.2086513994911, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24651633, Length=393, Percent_Identity=26.2086513994911, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221331183, Length=427, Percent_Identity=25.7611241217799, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17647653, Length=427, Percent_Identity=25.7611241217799, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24664379, Length=427, Percent_Identity=25.7611241217799, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550968, Length=423, Percent_Identity=24.3498817966903, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI19921172, Length=423, Percent_Identity=24.3498817966903, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641993, Length=426, Percent_Identity=24.8826291079812, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24641995, Length=426, Percent_Identity=24.8826291079812, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50448; Mature: 50317

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFRTKNLDHMIRTGQGDTGLKKVFGPLDLTFLGVGAIIGTGIFVLTGTGALTAGPALT
CCCCCCCCHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHH
LSFVVAALACGFAALCYAEFASTIPVSGSIYTYAYATLGELVAWIIGWDLMLEYGLATSA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVGWSGYFQSLMAGFGLHLPAALMAAPGAIPGVQTLFNLPALLIMLIITAVLSLGVRES
HHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ARFNNIMVAIKVAVVVLFIVVGARHVQPANWQPFMPFGMSGVFGAAALVFFAFIGFDAVT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAAEEVRNPERDLPIGIIGSLGVCTILYVVVAAIMTGIVPYTKFAGVDHPVSLALQMGGE
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
TWVAGFVDLGAIIGMTTVILVMGYGQTRVIFAMSRDGLLPKRLSRVHPRYATPFFNTWLV
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCHHHHHHH
GIVFALIAAFVPLNVLAELINIGTLAAFSLIAIAVLVLRRKRPDLPRGFRCPGVPFVPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
AVVLCVFLMSQLQALTWIAFVVWMVIGLLVYFGYARSRSLLHAPDRAAVPGSEAAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLFRTKNLDHMIRTGQGDTGLKKVFGPLDLTFLGVGAIIGTGIFVLTGTGALTAGPALT
CCCCCCCHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]