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The map label for this gene is rpoE1 [H]

Identifier: 17545774

GI number: 17545774

Start: 1108822

End: 1109421

Strand: Direct

Name: rpoE1 [H]

Synonym: RSc1055

Alternate gene names: 17545774

Gene position: 1108822-1109421 (Clockwise)

Preceding gene: 17545773

Following gene: 17545775

Centisome position: 29.84

GC content: 58.67

Gene sequence:

>600_bases
GTGAGTGAACGCGAAGCCGACCAGATCCTTGTCGAACGCGTCCAGCAGGGTGACAAGCGGGCGTTTGAACTGTTGGTGGT
CAAGTATCACCGCAAGATCATCCGTCTGATCTCACGCCTGATCCGCGATGCCGCGGAGGTGGAGGATGTGGCACAGGATG
CCTTCATCAAGGCGTACCGTGCGCTGCCCCAGTTCCGGGGCGAATCTGCGTTTTATACGTGGCTGTACCGCATCGCCGTT
AACACGGCCAAGAATTACCTGGCGACCCAGGGCCGGCGTCCCGAGTCGTCCACCGATATCGACACCGAAGAGGCTGAAAC
TTTTGCCGACGGTGAACAACTAAGGGATATCAATACGCCGGACTCGATGCTGCACACCAAGCAGGTTGCCGAAACGGTCA
ATCGCGCGATGGAGGCGTTGCCGGAGGAATTGCGTACGGCAATTACGCTCCGCGAGATCGAGGGTCTGAGCTATGAGGAA
ATCGCTGAAGCGATGGAATGTCCGATCGGGACCGTCCGTTCGCGGATATTTCGGGCACGCGAGGCGATTGCCGAGAAATT
GCGCCCCTTGCTGGGAACAGCAGAGGGCAAACGGTGGTAG

Upstream 100 bases:

>100_bases
CCATCTGTGTCTGGGGGCCTGGCATCCGGTGTGTCGTAGGTAAAATACAACGTTTTCAAGTCACAAAAATTCAAGGCGAT
ACACTGCAGGTGAAGAATCC

Downstream 100 bases:

>100_bases
CCAGCCGATATGACAAACCGGGCTGCCTGCGTCCAGGCTGCAAACGGTGAAATCTCGGGAAGTCTTCTCTCGGATCGTTG
ATTGAACGTTGGAGTTTTGG

Product: RNA polymerase sigma factor RpoE

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MSEREADQILVERVQQGDKRAFELLVVKYHRKIIRLISRLIRDAAEVEDVAQDAFIKAYRALPQFRGESAFYTWLYRIAV
NTAKNYLATQGRRPESSTDIDTEEAETFADGEQLRDINTPDSMLHTKQVAETVNRAMEALPEELRTAITLREIEGLSYEE
IAEAMECPIGTVRSRIFRAREAIAEKLRPLLGTAEGKRW

Sequences:

>Translated_199_residues
MSEREADQILVERVQQGDKRAFELLVVKYHRKIIRLISRLIRDAAEVEDVAQDAFIKAYRALPQFRGESAFYTWLYRIAV
NTAKNYLATQGRRPESSTDIDTEEAETFADGEQLRDINTPDSMLHTKQVAETVNRAMEALPEELRTAITLREIEGLSYEE
IAEAMECPIGTVRSRIFRAREAIAEKLRPLLGTAEGKRW
>Mature_198_residues
SEREADQILVERVQQGDKRAFELLVVKYHRKIIRLISRLIRDAAEVEDVAQDAFIKAYRALPQFRGESAFYTWLYRIAVN
TAKNYLATQGRRPESSTDIDTEEAETFADGEQLRDINTPDSMLHTKQVAETVNRAMEALPEELRTAITLREIEGLSYEEI
AEAMECPIGTVRSRIFRAREAIAEKLRPLLGTAEGKRW

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=191, Percent_Identity=61.7801047120419, Blast_Score=246, Evalue=8e-67,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 22845; Mature: 22714

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEREADQILVERVQQGDKRAFELLVVKYHRKIIRLISRLIRDAAEVEDVAQDAFIKAYR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPQFRGESAFYTWLYRIAVNTAKNYLATQGRRPESSTDIDTEEAETFADGEQLRDINTP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCHHHHHCCCCC
DSMLHTKQVAETVNRAMEALPEELRTAITLREIEGLSYEEIAEAMECPIGTVRSRIFRAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHH
EAIAEKLRPLLGTAEGKRW
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEREADQILVERVQQGDKRAFELLVVKYHRKIIRLISRLIRDAAEVEDVAQDAFIKAYR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPQFRGESAFYTWLYRIAVNTAKNYLATQGRRPESSTDIDTEEAETFADGEQLRDINTP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCHHHHHCCCCC
DSMLHTKQVAETVNRAMEALPEELRTAITLREIEGLSYEEIAEAMECPIGTVRSRIFRAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHH
EAIAEKLRPLLGTAEGKRW
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]