Click here to switch to the map view.

The map label for this gene is uup-A [H]

Identifier: 17545694

GI number: 17545694

Start: 1022803

End: 1024713

Strand: Direct

Name: uup-A [H]

Synonym: RSc0975

Alternate gene names: 17545694

Gene position: 1022803-1024713 (Clockwise)

Preceding gene: 17545691

Following gene: 17545695

Centisome position: 27.52

GC content: 69.39

Gene sequence:

>1911_bases
ATGGCCCTGTTTTCCATTACCGATGCGCAATTGGCCTTTGGCCATGTGGCGCTGCTCGACCACACCGATTTTTCGCTGGA
GGCCGGCGAGCGCGTCGGCCTGATCGGCCGCAACGGCACCGGCAAGTCCTCGCTGCTCAAGATCGTGGCTGGCCAGACGG
CGCCCGACGATGGGCTGATCGCGCGCCAGAGCGGCGTCATCTCCGCCTACGTGCCGCAGGAGCCGGTGTTCGATCCGGAC
CAGACCGTGGCCGAGGCGGTCGCCATGGGCGTGCCGCAGGCCGCCGCGCTGCTGGCCGAATACGAAGCGCTGGTCACCTC
GATGGGCGAATCGCACGACGAGGCCGCATTGCAGCGGCTGCACGCGCTGCAGGCGCAGCTGGAGGCCGCGGACGCCTGGC
AGCTGCGCACGCGTGTGGAGACCACCATCGCCCAGCTCGGCCTGACGCCCGGCGTGCGCATCGGCGCGCTGTCGGGTGGC
CTCACCAAGCGCGTGGCGCTCGCGCAGGCGCTGGTCGGCGCGCCCGACATCCTGATGCTGGACGAGCCGACCAACCACCT
CGACTACGATTCGATCCGCTGGCTCGAAGACCTGCTGCTGGCCTTTCGCGGCAGCGTGCTGTTCATCACGCACGACCGGG
CGTTCCTGGACCGCGTCGCCACGCGCATCGTCGAGCTCGACCGCGGCAAGCTGCGCTCGTATCCCGGCAACTTCTCCGCC
TACCAGGCGCGCAAGGCGCAGCAGCTCGAGGCCGAGGCGCTGGAGAACGCGCGCTTCGACAAGCTGCTCGCGCAGGAAGA
GGTCTGGATCCGCAAGGGCGTGGAAGCGCGCCGCACCCGCAGCGTAGGCCGCGTGGCCCGGCTCGTGCAGATGCGCGAGG
AGCACGCCGCGCGCCGCGAGGTGCAGGGCAACGTCAAGCTGGAGGTGTCGCAGGGCGACCGCTCCGGCAAGATCGTCGCC
GAGCTGGTCGATGTGGCCAAGCATTATGGCGACAAGGCCGTGGTGCGCGATTTCTCCGCCACCATCCTGCGCGGCGACAA
GGTCGGCCTGCTGGGCCCGAACGGTGTCGGCAAGACCACGCTGCTCAAGCTGATCCTGGGCGAGCTGGCGCCGGATGCGG
GCACGGTGCGCAACGGCACCAACCTGCAGGTGGCGTATTTCGACCAGATGCGCGCGCAGCTCGACCTGAACCGCTCGCTG
GCCGATACCATCAGCCCGGGCAGCGACTGGATCGACATCAACGGCCAGCGCAAGCACGTGATGAGCTACCTGGGCGATTT
CCTCTTTCCGCCCGAGCGGGCGCGCTCGCCGGTGGCGTCGCTCTCGGGCGGCGAGCGCAACCGGCTGCTGCTGGCGCGCC
TGTTCGCGCGGCCGGCCAATGCGCTGGTGCTCGATGAGCCGACCAACGATCTCGACATCGACACGCTGGAGCTGCTCGAA
GAGCTGCTGCAGGAATACAGCGGCACCGTGTTCCTGGTTTCGCACGACCGTGCTTTCGTCGACAACGTCGTCACCTCGGT
GATCGCGGCCGAGGGCGACGGCGTGTGGCGCGAATACGTGGGCGGGTTCTCCGACTGGCAGACGCAGTCGGCGCGCTCGG
CGCGGCTCGCGCAGGTCGCCAGGCCGGTCGCCGAAGAGAAGAAGGCTGAGCCGGTGCGTCCGCGCGAGCGGGCCACCGTC
AAGCTGTCGTACAAGGAGCAGCGCGAGCTGGATGCGCTGCCGGCCAGGATCGAGGCGCTGGAGGCTGAGCAGAAGGCCGT
GGGCGCCGAGCTGGAAGACGGCACGATCTACGGGCGCGATCCGCAGCGCGCGCAGCAGCTGGCCGAGCGGCACGAGGCGA
TCGAGCTCGAGCTGCTGGAAGTGCTGGAGCGCTGGGAAACGCTGGAAAGCAAGCGCGCCGGCACGGCCTGA

Upstream 100 bases:

>100_bases
GGTGCCTGCAAGCGCAATGACGCACCGCGTGGCCCGCGCGCGCCGACTACAATACGCGGCTTCCGGGCGCCGTCGTGCCC
GCTTCTTTCCGTTTTCCGGC

Downstream 100 bases:

>100_bases
CGCTGCGCCATGCGTCCGGGCAGGCCCGGGTGATGCGCCCCGATATCGGTCCGGCGCTGCCCGGCCGGCGGCGTCCACAT
TTCGTGTCACGTTGGCCGGG

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 636; Mature: 635

Protein sequence:

>636_residues
MALFSITDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGTGKSSLLKIVAGQTAPDDGLIARQSGVISAYVPQEPVFDPD
QTVAEAVAMGVPQAAALLAEYEALVTSMGESHDEAALQRLHALQAQLEAADAWQLRTRVETTIAQLGLTPGVRIGALSGG
LTKRVALAQALVGAPDILMLDEPTNHLDYDSIRWLEDLLLAFRGSVLFITHDRAFLDRVATRIVELDRGKLRSYPGNFSA
YQARKAQQLEAEALENARFDKLLAQEEVWIRKGVEARRTRSVGRVARLVQMREEHAARREVQGNVKLEVSQGDRSGKIVA
ELVDVAKHYGDKAVVRDFSATILRGDKVGLLGPNGVGKTTLLKLILGELAPDAGTVRNGTNLQVAYFDQMRAQLDLNRSL
ADTISPGSDWIDINGQRKHVMSYLGDFLFPPERARSPVASLSGGERNRLLLARLFARPANALVLDEPTNDLDIDTLELLE
ELLQEYSGTVFLVSHDRAFVDNVVTSVIAAEGDGVWREYVGGFSDWQTQSARSARLAQVARPVAEEKKAEPVRPRERATV
KLSYKEQRELDALPARIEALEAEQKAVGAELEDGTIYGRDPQRAQQLAERHEAIELELLEVLERWETLESKRAGTA

Sequences:

>Translated_636_residues
MALFSITDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGTGKSSLLKIVAGQTAPDDGLIARQSGVISAYVPQEPVFDPD
QTVAEAVAMGVPQAAALLAEYEALVTSMGESHDEAALQRLHALQAQLEAADAWQLRTRVETTIAQLGLTPGVRIGALSGG
LTKRVALAQALVGAPDILMLDEPTNHLDYDSIRWLEDLLLAFRGSVLFITHDRAFLDRVATRIVELDRGKLRSYPGNFSA
YQARKAQQLEAEALENARFDKLLAQEEVWIRKGVEARRTRSVGRVARLVQMREEHAARREVQGNVKLEVSQGDRSGKIVA
ELVDVAKHYGDKAVVRDFSATILRGDKVGLLGPNGVGKTTLLKLILGELAPDAGTVRNGTNLQVAYFDQMRAQLDLNRSL
ADTISPGSDWIDINGQRKHVMSYLGDFLFPPERARSPVASLSGGERNRLLLARLFARPANALVLDEPTNDLDIDTLELLE
ELLQEYSGTVFLVSHDRAFVDNVVTSVIAAEGDGVWREYVGGFSDWQTQSARSARLAQVARPVAEEKKAEPVRPRERATV
KLSYKEQRELDALPARIEALEAEQKAVGAELEDGTIYGRDPQRAQQLAERHEAIELELLEVLERWETLESKRAGTA
>Mature_635_residues
ALFSITDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGTGKSSLLKIVAGQTAPDDGLIARQSGVISAYVPQEPVFDPDQ
TVAEAVAMGVPQAAALLAEYEALVTSMGESHDEAALQRLHALQAQLEAADAWQLRTRVETTIAQLGLTPGVRIGALSGGL
TKRVALAQALVGAPDILMLDEPTNHLDYDSIRWLEDLLLAFRGSVLFITHDRAFLDRVATRIVELDRGKLRSYPGNFSAY
QARKAQQLEAEALENARFDKLLAQEEVWIRKGVEARRTRSVGRVARLVQMREEHAARREVQGNVKLEVSQGDRSGKIVAE
LVDVAKHYGDKAVVRDFSATILRGDKVGLLGPNGVGKTTLLKLILGELAPDAGTVRNGTNLQVAYFDQMRAQLDLNRSLA
DTISPGSDWIDINGQRKHVMSYLGDFLFPPERARSPVASLSGGERNRLLLARLFARPANALVLDEPTNDLDIDTLELLEE
LLQEYSGTVFLVSHDRAFVDNVVTSVIAAEGDGVWREYVGGFSDWQTQSARSARLAQVARPVAEEKKAEPVRPRERATVK
LSYKEQRELDALPARIEALEAEQKAVGAELEDGTIYGRDPQRAQQLAERHEAIELELLEVLERWETLESKRAGTA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=536, Percent_Identity=32.6492537313433, Blast_Score=225, Evalue=1e-58,
Organism=Homo sapiens, GI10947137, Length=525, Percent_Identity=31.4285714285714, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI27881506, Length=525, Percent_Identity=31.4285714285714, Blast_Score=206, Evalue=7e-53,
Organism=Homo sapiens, GI10947135, Length=548, Percent_Identity=29.5620437956204, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI69354671, Length=548, Percent_Identity=29.5620437956204, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI150417984, Length=225, Percent_Identity=30.2222222222222, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI9955968, Length=230, Percent_Identity=29.1304347826087, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI9955966, Length=233, Percent_Identity=29.6137339055794, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI45243524, Length=233, Percent_Identity=29.6137339055794, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1787182, Length=634, Percent_Identity=48.2649842271293, Blast_Score=563, Evalue=1e-162,
Organism=Escherichia coli, GI2367384, Length=522, Percent_Identity=36.9731800766284, Blast_Score=332, Evalue=4e-92,
Organism=Escherichia coli, GI1787041, Length=527, Percent_Identity=30.550284629981, Blast_Score=252, Evalue=5e-68,
Organism=Escherichia coli, GI1789751, Length=647, Percent_Identity=30.4482225656878, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1788165, Length=192, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788506, Length=556, Percent_Identity=25.1798561151079, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1787792, Length=526, Percent_Identity=24.5247148288973, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI87081782, Length=506, Percent_Identity=25.098814229249, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI145693107, Length=680, Percent_Identity=22.5, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787164, Length=181, Percent_Identity=32.5966850828729, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081709, Length=226, Percent_Identity=27.8761061946903, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786703, Length=225, Percent_Identity=30.6666666666667, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1787370, Length=234, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI48994883, Length=250, Percent_Identity=25.2, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI87081791, Length=197, Percent_Identity=29.4416243654822, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787712, Length=200, Percent_Identity=29.5, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=541, Percent_Identity=28.0961182994455, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17553372, Length=547, Percent_Identity=29.7989031078611, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17555318, Length=511, Percent_Identity=26.614481409002, Blast_Score=185, Evalue=6e-47,
Organism=Saccharomyces cerevisiae, GI6320874, Length=552, Percent_Identity=29.1666666666667, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6321121, Length=550, Percent_Identity=27.0909090909091, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6325030, Length=395, Percent_Identity=29.3670886075949, Blast_Score=140, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6323278, Length=387, Percent_Identity=26.0981912144703, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324314, Length=387, Percent_Identity=25.5813953488372, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24666836, Length=536, Percent_Identity=30.2238805970149, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24642252, Length=546, Percent_Identity=28.5714285714286, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI18859989, Length=546, Percent_Identity=28.5714285714286, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24641342, Length=527, Percent_Identity=28.2732447817837, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI221500365, Length=201, Percent_Identity=32.3383084577114, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007184, Length=201, Percent_Identity=32.3383084577114, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24659289, Length=220, Percent_Identity=26.8181818181818, Blast_Score=66, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 69800; Mature: 69669

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALFSITDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGTGKSSLLKIVAGQTAPDDGLI
CCEEEECCHHHHHCEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCE
ARQSGVISAYVPQEPVFDPDQTVAEAVAMGVPQAAALLAEYEALVTSMGESHDEAALQRL
EECCCCEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
HALQAQLEAADAWQLRTRVETTIAQLGLTPGVRIGALSGGLTKRVALAQALVGAPDILML
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEE
DEPTNHLDYDSIRWLEDLLLAFRGSVLFITHDRAFLDRVATRIVELDRGKLRSYPGNFSA
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCHHHHCCCCCCHH
YQARKAQQLEAEALENARFDKLLAQEEVWIRKGVEARRTRSVGRVARLVQMREEHAARRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VQGNVKLEVSQGDRSGKIVAELVDVAKHYGDKAVVRDFSATILRGDKVGLLGPNGVGKTT
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHH
LLKLILGELAPDAGTVRNGTNLQVAYFDQMRAQLDLNRSLADTISPGSDWIDINGQRKHV
HHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHCCCCCCEEECCCCHHHH
MSYLGDFLFPPERARSPVASLSGGERNRLLLARLFARPANALVLDEPTNDLDIDTLELLE
HHHHHHHCCCCHHHCCCHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHH
ELLQEYSGTVFLVSHDRAFVDNVVTSVIAAEGDGVWREYVGGFSDWQTQSARSARLAQVA
HHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHH
RPVAEEKKAEPVRPRERATVKLSYKEQRELDALPARIEALEAEQKAVGAELEDGTIYGRD
HHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC
PQRAQQLAERHEAIELELLEVLERWETLESKRAGTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ALFSITDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGTGKSSLLKIVAGQTAPDDGLI
CEEEECCHHHHHCEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCE
ARQSGVISAYVPQEPVFDPDQTVAEAVAMGVPQAAALLAEYEALVTSMGESHDEAALQRL
EECCCCEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
HALQAQLEAADAWQLRTRVETTIAQLGLTPGVRIGALSGGLTKRVALAQALVGAPDILML
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEE
DEPTNHLDYDSIRWLEDLLLAFRGSVLFITHDRAFLDRVATRIVELDRGKLRSYPGNFSA
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCHHHHCCCCCCHH
YQARKAQQLEAEALENARFDKLLAQEEVWIRKGVEARRTRSVGRVARLVQMREEHAARRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VQGNVKLEVSQGDRSGKIVAELVDVAKHYGDKAVVRDFSATILRGDKVGLLGPNGVGKTT
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHH
LLKLILGELAPDAGTVRNGTNLQVAYFDQMRAQLDLNRSLADTISPGSDWIDINGQRKHV
HHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHCCCCCCEEECCCCHHHH
MSYLGDFLFPPERARSPVASLSGGERNRLLLARLFARPANALVLDEPTNDLDIDTLELLE
HHHHHHHCCCCHHHCCCHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHH
ELLQEYSGTVFLVSHDRAFVDNVVTSVIAAEGDGVWREYVGGFSDWQTQSARSARLAQVA
HHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHH
RPVAEEKKAEPVRPRERATVKLSYKEQRELDALPARIEALEAEQKAVGAELEDGTIYGRD
HHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC
PQRAQQLAERHEAIELELLEVLERWETLESKRAGTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]