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The map label for this gene is gyrA [H]

Identifier: 17545620

GI number: 17545620

Start: 950444

End: 953101

Strand: Direct

Name: gyrA [H]

Synonym: RSc0901

Alternate gene names: 17545620

Gene position: 950444-953101 (Clockwise)

Preceding gene: 17545618

Following gene: 17545621

Centisome position: 25.57

GC content: 63.69

Gene sequence:

>2658_bases
ATGGATCAATTCGCCAAAGAGACACTCCCGGTATCGCTCGAAGAAGAAATGCGCAGTTCATACCTCGCTTACGCCATGAG
CGTAATCGTGGGCCGCGCGCTTCCGGACGTGCGGGATGGTCTCAAGCCGGTGCATCGCCGCGTGCTGTACGCGATGCACG
AGCTGAACAACGACTGGAACCGTCCCTACAAGAAGTCGGCACGTATCGTCGGTGACGTGATCGGTAAGTACCACCCGCAC
GGCGACTCCGCGGTCTATGACACCATCGTGCGGATGGCACAGGATTTCTCGCTGCGCTACATGCTGGTCGACGGCCAGGG
CAACTTCGGCTCGGTCGACGGCGACAACGCGGCGGCGATGCGTTACACGGAAATCCGCCTGTCGAAGATCGCCCACGAGC
TGCTGGCCGACATCGACAAGGAAACCGTCGATTTCGAGCCGAACTACGACGGCAGCGAAACCGAGCCGTCCATCCTGCCC
GCGCGCATTCCGAACTTGCTGATCAACGGCTCGTCCGGGATCGCGGTCGGCATGGCGACCAACATCCCGCCGCACAACCT
AAGGGAGGTGGTGGACGGCTGTCTGCACCTGCTGCGCAACCCGGATGCGACGGTCGACGAACTGATCGAGCTGATCCCGG
CGCCGGATTTCCCGACCGCCGGCATCATCTACGGCATCTCGGGCGTGCGCGAGGGCTATCGCACCGGCCGTGGCCGCGTG
GTGATGCGTGCCAAGACGCACTTCGAGGATATCGACCGCGGTCAGCGCCAGGCGATCATCGTCGATGAGCTGCCCTATCA
AGTTAACAAGCGCACGCTGCTCGAGCGGATCGCCGAACTGGTGACCGAAAAGCGCATCGAGGGCATTTCCGATATCCGCG
ACGAGTCCGACAAGTCGGGCATGCGCGTGGTGATCGAGCTCAAGCGTGGCGAAGTGCCGGAGGTCGTGCTCAACAACCTC
TATAAGAATACGCAGTTGCAGGACACGTTCGGCATGAACATGGTGGCGCTGGTCGACGGCCAGCCCCGCCTGCTGAACCT
GCGCCAGATGCTGGAGTGCTTCCTGCTGCACCGCCGCGAGGTGGTGACGCGTCGCACGGTGTTCGATCTGCGCAAGGCGC
GCGAGCGGGGGCACATCCTCGAGGGGCTGGCCGTGGCGCTGGCCAATATCGACGAGTTCATCGCCATCATCAAGGCTGCG
CCGACACCTCCGATCGCCAAGCAGGAACTGATGGGTCGCAACTGGGATTCGGGCCTGGTGCGCGAGATGCTGTCGCGGGC
CGAGAGCGACACCGTCGGCGGCCGTGCCGCCTATCGTCCGGAAGGGCTGCTGCCCGTTTTCGGCATGCAGGAGGGGGGGC
TCTACAAGCTGTCCGACACGCAGGCCCAGGAAATCCTGCAGATGCGCCTGCAACGCCTCACGGGGCTGGAGCAGGACAAG
ATCGTCCAGGAATACCGCGAAGTGATGGCGCAGATTGCCGACCTGCTGGACATCCTGGCGCGCCCGGAGCGCATTACTGC
GATCATCGTCGAGGAACTCACGCTGATTCGCGCGGAATTCGGCGACGAGCGTCGCTCGCAGATCGAGCATAATGCGACCG
AGTTGGACACCGAAGACCTCATTACGCCGCAGGATCTGGTGGTGACGCTGTCCCACAGCGGCTATATGAAGAGCCAGCCG
ATCTCCGAATACCGCGCGCAGAAGCGTGGCGGGCGCGGCAAGCAAGCCGCCGCCACCAAGGAAGATGACTGGATCGACAC
GCTATTTGTCGCCAACACGCACGATTACATCCTCTGCTTCTCCAATCGCGGCCGTCTCTACTGGCTCAAGGTGTGGGAGG
TGCCGCAAGGCAGCCGCAATTCGCGCGGGCGCCCGATCGTCAACATGTTCCCGCTGTCGCCCGGCGAGAAGATCAATGTG
ATCTTGCCGGTCAAGCAGTTCGATGAGCAGCACTTCGTCTTCATGGCCACTTCCAAGGGCACGGTCAAGAAAACGGCGCT
CACCGAATTCTCCAACCCGCGCAAGGCCGGCATCATCGCCGTGGACCTCGATGACGGCGATTTCCTGATCGGCGCGGATA
TCACCGATGGCCAGCATGATGTGATGCTGTTCTCGGACGCCGGCAAGGCGGTCCGCTTTGACGAGAACGATGTCCGCCCG
ATGGGCCGTCAGGCGCGCGGGGTGCGGGGCATGAACCTGGAGGAAGGCCAGCAGGTGATCGCCATGCTGGTGGCGCCGGC
CGAAACGGCGGGCGAAGGCGAGCAGGCGGTGGCGGGCAGTGTGCTGACCGCTACCGAGAACGGCTACGGCAAGCGCACGC
CGATCTCCGAGTACACCCGCCATGGCCGCGGCACCAAGGGCATGATCGCGATCCAGACCTCCGAGCGCAACGGCAAGGTG
GTCGCGGCCGCGCTGGTGGCGCCCGAGGACGAGATCATGCTGATCACGACCGGCGGTGTGCTGATCCGTACCCGCGTGGA
TGAGATCCGCGAGATGGGGCGCGCCACCCAGGGCGTCACGCTGATTGCTGTGGGCGAGGGTAACAAATTGTCCGGGCTGC
AACGTGTGGTGGAGTCGGATGCCGAGGGCGAAGATGCCGCCGATGGCGGGCCGGAATCCGATGGCGAAGCGCCGGACGCG
GATACCGCCGAAACATAA

Upstream 100 bases:

>100_bases
GTCGCCTCCGGCAGTGAGGGGGGAGGGCTGGCGGCATGGTAAAATAGTCTGTTATTCGCGCAACCGCAGCGCCCTTTGCG
GGGCCCCCATCGTTCGCCCA

Downstream 100 bases:

>100_bases
TTCGAAACATTTTTCGCTTGCCGCGATGCTTCGTTCTGGCATGATGCCGGACTTGCGTGCGGCATGGCCCGGAACTCGGG
ACCCTCTGTCCGGACTAAAC

Product: DNA gyrase subunit A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 885; Mature: 885

Protein sequence:

>885_residues
MDQFAKETLPVSLEEEMRSSYLAYAMSVIVGRALPDVRDGLKPVHRRVLYAMHELNNDWNRPYKKSARIVGDVIGKYHPH
GDSAVYDTIVRMAQDFSLRYMLVDGQGNFGSVDGDNAAAMRYTEIRLSKIAHELLADIDKETVDFEPNYDGSETEPSILP
ARIPNLLINGSSGIAVGMATNIPPHNLREVVDGCLHLLRNPDATVDELIELIPAPDFPTAGIIYGISGVREGYRTGRGRV
VMRAKTHFEDIDRGQRQAIIVDELPYQVNKRTLLERIAELVTEKRIEGISDIRDESDKSGMRVVIELKRGEVPEVVLNNL
YKNTQLQDTFGMNMVALVDGQPRLLNLRQMLECFLLHRREVVTRRTVFDLRKARERGHILEGLAVALANIDEFIAIIKAA
PTPPIAKQELMGRNWDSGLVREMLSRAESDTVGGRAAYRPEGLLPVFGMQEGGLYKLSDTQAQEILQMRLQRLTGLEQDK
IVQEYREVMAQIADLLDILARPERITAIIVEELTLIRAEFGDERRSQIEHNATELDTEDLITPQDLVVTLSHSGYMKSQP
ISEYRAQKRGGRGKQAAATKEDDWIDTLFVANTHDYILCFSNRGRLYWLKVWEVPQGSRNSRGRPIVNMFPLSPGEKINV
ILPVKQFDEQHFVFMATSKGTVKKTALTEFSNPRKAGIIAVDLDDGDFLIGADITDGQHDVMLFSDAGKAVRFDENDVRP
MGRQARGVRGMNLEEGQQVIAMLVAPAETAGEGEQAVAGSVLTATENGYGKRTPISEYTRHGRGTKGMIAIQTSERNGKV
VAAALVAPEDEIMLITTGGVLIRTRVDEIREMGRATQGVTLIAVGEGNKLSGLQRVVESDAEGEDAADGGPESDGEAPDA
DTAET

Sequences:

>Translated_885_residues
MDQFAKETLPVSLEEEMRSSYLAYAMSVIVGRALPDVRDGLKPVHRRVLYAMHELNNDWNRPYKKSARIVGDVIGKYHPH
GDSAVYDTIVRMAQDFSLRYMLVDGQGNFGSVDGDNAAAMRYTEIRLSKIAHELLADIDKETVDFEPNYDGSETEPSILP
ARIPNLLINGSSGIAVGMATNIPPHNLREVVDGCLHLLRNPDATVDELIELIPAPDFPTAGIIYGISGVREGYRTGRGRV
VMRAKTHFEDIDRGQRQAIIVDELPYQVNKRTLLERIAELVTEKRIEGISDIRDESDKSGMRVVIELKRGEVPEVVLNNL
YKNTQLQDTFGMNMVALVDGQPRLLNLRQMLECFLLHRREVVTRRTVFDLRKARERGHILEGLAVALANIDEFIAIIKAA
PTPPIAKQELMGRNWDSGLVREMLSRAESDTVGGRAAYRPEGLLPVFGMQEGGLYKLSDTQAQEILQMRLQRLTGLEQDK
IVQEYREVMAQIADLLDILARPERITAIIVEELTLIRAEFGDERRSQIEHNATELDTEDLITPQDLVVTLSHSGYMKSQP
ISEYRAQKRGGRGKQAAATKEDDWIDTLFVANTHDYILCFSNRGRLYWLKVWEVPQGSRNSRGRPIVNMFPLSPGEKINV
ILPVKQFDEQHFVFMATSKGTVKKTALTEFSNPRKAGIIAVDLDDGDFLIGADITDGQHDVMLFSDAGKAVRFDENDVRP
MGRQARGVRGMNLEEGQQVIAMLVAPAETAGEGEQAVAGSVLTATENGYGKRTPISEYTRHGRGTKGMIAIQTSERNGKV
VAAALVAPEDEIMLITTGGVLIRTRVDEIREMGRATQGVTLIAVGEGNKLSGLQRVVESDAEGEDAADGGPESDGEAPDA
DTAET
>Mature_885_residues
MDQFAKETLPVSLEEEMRSSYLAYAMSVIVGRALPDVRDGLKPVHRRVLYAMHELNNDWNRPYKKSARIVGDVIGKYHPH
GDSAVYDTIVRMAQDFSLRYMLVDGQGNFGSVDGDNAAAMRYTEIRLSKIAHELLADIDKETVDFEPNYDGSETEPSILP
ARIPNLLINGSSGIAVGMATNIPPHNLREVVDGCLHLLRNPDATVDELIELIPAPDFPTAGIIYGISGVREGYRTGRGRV
VMRAKTHFEDIDRGQRQAIIVDELPYQVNKRTLLERIAELVTEKRIEGISDIRDESDKSGMRVVIELKRGEVPEVVLNNL
YKNTQLQDTFGMNMVALVDGQPRLLNLRQMLECFLLHRREVVTRRTVFDLRKARERGHILEGLAVALANIDEFIAIIKAA
PTPPIAKQELMGRNWDSGLVREMLSRAESDTVGGRAAYRPEGLLPVFGMQEGGLYKLSDTQAQEILQMRLQRLTGLEQDK
IVQEYREVMAQIADLLDILARPERITAIIVEELTLIRAEFGDERRSQIEHNATELDTEDLITPQDLVVTLSHSGYMKSQP
ISEYRAQKRGGRGKQAAATKEDDWIDTLFVANTHDYILCFSNRGRLYWLKVWEVPQGSRNSRGRPIVNMFPLSPGEKINV
ILPVKQFDEQHFVFMATSKGTVKKTALTEFSNPRKAGIIAVDLDDGDFLIGADITDGQHDVMLFSDAGKAVRFDENDVRP
MGRQARGVRGMNLEEGQQVIAMLVAPAETAGEGEQAVAGSVLTATENGYGKRTPISEYTRHGRGTKGMIAIQTSERNGKV
VAAALVAPEDEIMLITTGGVLIRTRVDEIREMGRATQGVTLIAVGEGNKLSGLQRVVESDAEGEDAADGGPESDGEAPDA
DTAET

Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]

COG id: COG0188

COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the topoisomerase gyrA/parC subunit family [H]

Homologues:

Organism=Homo sapiens, GI19913408, Length=320, Percent_Identity=26.875, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI19913406, Length=407, Percent_Identity=27.027027027027, Blast_Score=95, Evalue=3e-19,
Organism=Escherichia coli, GI1788562, Length=885, Percent_Identity=60.5649717514124, Blast_Score=1069, Evalue=0.0,
Organism=Escherichia coli, GI1789396, Length=764, Percent_Identity=35.4712041884817, Blast_Score=398, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17535065, Length=492, Percent_Identity=24.7967479674797, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI212645657, Length=352, Percent_Identity=25.2840909090909, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI212645845, Length=189, Percent_Identity=31.2169312169312, Blast_Score=76, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI115534553, Length=171, Percent_Identity=30.4093567251462, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324241, Length=352, Percent_Identity=26.9886363636364, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17136538, Length=352, Percent_Identity=24.7159090909091, Blast_Score=84, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020899
- InterPro:   IPR005743
- InterPro:   IPR006691
- InterPro:   IPR002205
- InterPro:   IPR013758
- InterPro:   IPR013757
- InterPro:   IPR013760 [H]

Pfam domain/function: PF03989 DNA_gyraseA_C; PF00521 DNA_topoisoIV [H]

EC number: =5.99.1.3 [H]

Molecular weight: Translated: 98147; Mature: 98147

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQFAKETLPVSLEEEMRSSYLAYAMSVIVGRALPDVRDGLKPVHRRVLYAMHELNNDWN
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
RPYKKSARIVGDVIGKYHPHGDSAVYDTIVRMAQDFSLRYMLVDGQGNFGSVDGDNAAAM
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCEE
RYTEIRLSKIAHELLADIDKETVDFEPNYDGSETEPSILPARIPNLLINGSSGIAVGMAT
EHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCEEEECCCCEEEEEEC
NIPPHNLREVVDGCLHLLRNPDATVDELIELIPAPDFPTAGIIYGISGVREGYRTGRGRV
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHCCCCEE
VMRAKTHFEDIDRGQRQAIIVDELPYQVNKRTLLERIAELVTEKRIEGISDIRDESDKSG
EEEEHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
MRVVIELKRGEVPEVVLNNLYKNTQLQDTFGMNMVALVDGQPRLLNLRQMLECFLLHRRE
CEEEEEECCCCCHHHHHHHHHCCCCCCHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
VVTRRTVFDLRKARERGHILEGLAVALANIDEFIAIIKAAPTPPIAKQELMGRNWDSGLV
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHH
REMLSRAESDTVGGRAAYRPEGLLPVFGMQEGGLYKLSDTQAQEILQMRLQRLTGLEQDK
HHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCHHHHHHHHHHHHHHCCCCHHH
IVQEYREVMAQIADLLDILARPERITAIIVEELTLIRAEFGDERRSQIEHNATELDTEDL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHCCHHHC
ITPQDLVVTLSHSGYMKSQPISEYRAQKRGGRGKQAAATKEDDWIDTLFVANTHDYILCF
CCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEE
SNRGRLYWLKVWEVPQGSRNSRGRPIVNMFPLSPGEKINVILPVKQFDEQHFVFMATSKG
CCCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCCCEEEEEEEHHHCCCCEEEEEEECCC
TVKKTALTEFSNPRKAGIIAVDLDDGDFLIGADITDGQHDVMLFSDAGKAVRFDENDVRP
CCHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCCCCCEEEEECCCCEEECCCCCCCC
MGRQARGVRGMNLEEGQQVIAMLVAPAETAGEGEQAVAGSVLTATENGYGKRTPISEYTR
CCHHHCCCCCCCHHHHHHHHHHHEECCCCCCCCCHHHCCEEEEECCCCCCCCCCHHHHHH
HGRGTKGMIAIQTSERNGKVVAAALVAPEDEIMLITTGGVLIRTRVDEIREMGRATQGVT
CCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCEEEEEHHHHHHHHCCCCCCEE
LIAVGEGNKLSGLQRVVESDAEGEDAADGGPESDGEAPDADTAET
EEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDQFAKETLPVSLEEEMRSSYLAYAMSVIVGRALPDVRDGLKPVHRRVLYAMHELNNDWN
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
RPYKKSARIVGDVIGKYHPHGDSAVYDTIVRMAQDFSLRYMLVDGQGNFGSVDGDNAAAM
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCEE
RYTEIRLSKIAHELLADIDKETVDFEPNYDGSETEPSILPARIPNLLINGSSGIAVGMAT
EHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCEEEECCCCEEEEEEC
NIPPHNLREVVDGCLHLLRNPDATVDELIELIPAPDFPTAGIIYGISGVREGYRTGRGRV
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHCCCCEE
VMRAKTHFEDIDRGQRQAIIVDELPYQVNKRTLLERIAELVTEKRIEGISDIRDESDKSG
EEEEHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
MRVVIELKRGEVPEVVLNNLYKNTQLQDTFGMNMVALVDGQPRLLNLRQMLECFLLHRRE
CEEEEEECCCCCHHHHHHHHHCCCCCCHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
VVTRRTVFDLRKARERGHILEGLAVALANIDEFIAIIKAAPTPPIAKQELMGRNWDSGLV
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHH
REMLSRAESDTVGGRAAYRPEGLLPVFGMQEGGLYKLSDTQAQEILQMRLQRLTGLEQDK
HHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCHHHHHHHHHHHHHHCCCCHHH
IVQEYREVMAQIADLLDILARPERITAIIVEELTLIRAEFGDERRSQIEHNATELDTEDL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHCCHHHC
ITPQDLVVTLSHSGYMKSQPISEYRAQKRGGRGKQAAATKEDDWIDTLFVANTHDYILCF
CCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEE
SNRGRLYWLKVWEVPQGSRNSRGRPIVNMFPLSPGEKINVILPVKQFDEQHFVFMATSKG
CCCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCCCEEEEEEEHHHCCCCEEEEEEECCC
TVKKTALTEFSNPRKAGIIAVDLDDGDFLIGADITDGQHDVMLFSDAGKAVRFDENDVRP
CCHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCCCCCEEEEECCCCEEECCCCCCCC
MGRQARGVRGMNLEEGQQVIAMLVAPAETAGEGEQAVAGSVLTATENGYGKRTPISEYTR
CCHHHCCCCCCCHHHHHHHHHHHEECCCCCCCCCHHHCCEEEEECCCCCCCCCCHHHHHH
HGRGTKGMIAIQTSERNGKVVAAALVAPEDEIMLITTGGVLIRTRVDEIREMGRATQGVT
CCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCEEEEEHHHHHHHHCCCCCCEE
LIAVGEGNKLSGLQRVVESDAEGEDAADGGPESDGEAPDADTAET
EEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677609; 8849216 [H]