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The map label for this gene is gltK [H]

Identifier: 17545202

GI number: 17545202

Start: 519178

End: 519861

Strand: Direct

Name: gltK [H]

Synonym: RSc0483

Alternate gene names: 17545202

Gene position: 519178-519861 (Clockwise)

Preceding gene: 17545201

Following gene: 17545203

Centisome position: 13.97

GC content: 61.7

Gene sequence:

>684_bases
ATGGCTTATCAATTCGATTTCACGTCCGTCAACGCCGACAACCTGCGCGTGCTCGGCGAAGGCATGGTCCTGTCGCTCGA
GATCACGGCCACGGCCATTCTGGTCGGCATCGTCTGGGGCACGCTGCTGGCGATGATGCGCCTGTCGGGCATCAAGCCGC
TGCAGTGGTTCGGGCAGGCCTATGTGAACCTCTTCCGCTCCATCCCGCTGGTGATGGTGCTGCTGTGGTTCTTCCTGATC
GTGCCGCAGGTGCTGCAGAAGCTCTTCAACCTGTCGCCGGCCACCGACATGCGCATGACCTCCGCGCTGGTCGCCTTCGC
GCTGTTCGAGGCGGCGTACTACTCGGAGATCATCCGCGCCGGCATCCAGAGCGTCTCGCGCGGGCAGATGTTCGCGGCCT
ATGCGATGGGCATGACGTACGGCCAGGCCATGCGCCTGGTGATCCTGCCGCAGGCTTTCCGCAACATGATCCCGCTGCTG
CTCACGCAGGCCATCATCCTGTTCCAGGATACGTCGCTGGTGTATGTGAGCGCGCTGTCGGATTTCTTTACGCAGGCTTA
CAACATCGGTGAGCGCGATGGCCGCATCGTCGAGCTGCTGCTGTTTGCCGGCTTTTGCTATTTCGTGATCTGCTTCGGCG
CCTCCGTGCTGGTGAAGCGGCTTCAGAAGAAGGTGACCCAATGA

Upstream 100 bases:

>100_bases
TGATCAACCTGACCGTCATGGGAATCATGCGCTGGGTTGAAGCACGTACCCGGCTGCCCGGTTTCATCGGCGGCAAGTAA
GCCGGCACGCGAGGATATTC

Downstream 100 bases:

>100_bases
TCGAGATCAAGAACGTTTCCAAGTGGTACGGCCAGTTCCAAGTGCTGACCGACTGCACCACCAGCGTGAAGAAGAGCGAG
GTGGTGGTGGTGTGCGGCCC

Product: glutamate/aspartate transmembrane ABC transporter protein

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MAYQFDFTSVNADNLRVLGEGMVLSLEITATAILVGIVWGTLLAMMRLSGIKPLQWFGQAYVNLFRSIPLVMVLLWFFLI
VPQVLQKLFNLSPATDMRMTSALVAFALFEAAYYSEIIRAGIQSVSRGQMFAAYAMGMTYGQAMRLVILPQAFRNMIPLL
LTQAIILFQDTSLVYVSALSDFFTQAYNIGERDGRIVELLLFAGFCYFVICFGASVLVKRLQKKVTQ

Sequences:

>Translated_227_residues
MAYQFDFTSVNADNLRVLGEGMVLSLEITATAILVGIVWGTLLAMMRLSGIKPLQWFGQAYVNLFRSIPLVMVLLWFFLI
VPQVLQKLFNLSPATDMRMTSALVAFALFEAAYYSEIIRAGIQSVSRGQMFAAYAMGMTYGQAMRLVILPQAFRNMIPLL
LTQAIILFQDTSLVYVSALSDFFTQAYNIGERDGRIVELLLFAGFCYFVICFGASVLVKRLQKKVTQ
>Mature_226_residues
AYQFDFTSVNADNLRVLGEGMVLSLEITATAILVGIVWGTLLAMMRLSGIKPLQWFGQAYVNLFRSIPLVMVLLWFFLIV
PQVLQKLFNLSPATDMRMTSALVAFALFEAAYYSEIIRAGIQSVSRGQMFAAYAMGMTYGQAMRLVILPQAFRNMIPLLL
TQAIILFQDTSLVYVSALSDFFTQAYNIGERDGRIVELLLFAGFCYFVICFGASVLVKRLQKKVTQ

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=222, Percent_Identity=63.5135135135135, Blast_Score=294, Evalue=4e-81,
Organism=Escherichia coli, GI1788226, Length=215, Percent_Identity=33.0232558139535, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI87082239, Length=207, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786874, Length=181, Percent_Identity=28.7292817679558, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1787030, Length=221, Percent_Identity=27.1493212669683, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1787087, Length=228, Percent_Identity=24.5614035087719, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788645, Length=209, Percent_Identity=24.8803827751196, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI48994930, Length=123, Percent_Identity=30.0813008130081, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25453; Mature: 25322

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYQFDFTSVNADNLRVLGEGMVLSLEITATAILVGIVWGTLLAMMRLSGIKPLQWFGQA
CCEEECCCCCCCCCCEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YVNLFRSIPLVMVLLWFFLIVPQVLQKLFNLSPATDMRMTSALVAFALFEAAYYSEIIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GIQSVSRGQMFAAYAMGMTYGQAMRLVILPQAFRNMIPLLLTQAIILFQDTSLVYVSALS
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DFFTQAYNIGERDGRIVELLLFAGFCYFVICFGASVLVKRLQKKVTQ
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AYQFDFTSVNADNLRVLGEGMVLSLEITATAILVGIVWGTLLAMMRLSGIKPLQWFGQA
CEEECCCCCCCCCCEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YVNLFRSIPLVMVLLWFFLIVPQVLQKLFNLSPATDMRMTSALVAFALFEAAYYSEIIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GIQSVSRGQMFAAYAMGMTYGQAMRLVILPQAFRNMIPLLLTQAIILFQDTSLVYVSALS
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DFFTQAYNIGERDGRIVELLLFAGFCYFVICFGASVLVKRLQKKVTQ
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]