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The map label for this gene is ptxB [H]

Identifier: 17230230

GI number: 17230230

Start: 3335095

End: 3336141

Strand: Direct

Name: ptxB [H]

Synonym: alr2738

Alternate gene names: 17230230

Gene position: 3335095-3336141 (Clockwise)

Preceding gene: 17230229

Following gene: 17230231

Centisome position: 52.0

GC content: 39.16

Gene sequence:

>1047_bases
ATGAAAAAAGCCATGCAGTGGCTGATTAGTAGAAAAATGTTATTCAGTAGCCAGCTTGTTGTCGTAACTGCGATCGCCTG
TATACTTAGTATTGGTTGTCATAATAGCATTTCTAGTAAAAATCAGCCTCTTGTAAATAAAACCTCATCCCAGCTAGCCA
CAGACGATATTAGGGTAGTAAGAAGGACGAGGGAAAGACAAGGTACAGTGTATGATAATACCTCTGTATCCTCTGTAAGT
AGAAATGTTTTACCTAAACTAAAAATCGGACTACTGTCTACCCAAAATTTCACAGAACAACAGCAAATCATTAAACCCCT
GAATGATTACTTAGAAACCTCCCTGGGACGACAAGTCCATTTTTTCATAGCTAAAGATCACGAAGAAATTATAGAATGGT
TGACTCAAGACAAACTAGACCTTGCTTATTTAGGCTCTGTAGCTTATCTTGAGGCAGTAGATAGGGGTGCAGAAATTCAA
CCATTAGTGACTTCCATCGACAAACATACAGGCCAACCTTGGTATCGAGCTTGTATTATTGTCAAAGCTGATAGTTCTAT
CAAAACCTTAAAAGACCTCAAAGGCAAGCGCGTTGCTTTTGTAGATAAATCATCTACCTCTGGATATCTCATGCCACTAG
TAGCTCTTAGTAAACAAAGTATTGATCCTCAAAAGGACTTTAGAACGGTCATCTATGCCGGCAACCATAGAAAAAGTATA
GCAGCATTAGAAAATGGCTCTGTCGATGCAGCTGCAACTAATGTTTCTTCCTACATCACCTTCAAAAAAAGTGGTAAGCT
CACACCACAAGACTATAGATTAATTTGGGAATCTGCACCCATCCCTAATTTTCCTATAGTAATATCCCAAAAATTGGCAC
CAGAATTGATTCAACAGCTAAAGCAAGTTTTTATTAGTACCCCAGAAGGCATGAAAGATATTTTAGGAGCTGAATCAGCC
GGCTATACTCTTGTCGGCCCAGACCACTACGCTCCTATTCAACAACTCCGTCAAGAACTCAACTTAACATCCATCCCGAA
AAAATGA

Upstream 100 bases:

>100_bases
TACGACGGCATTTTTTGAGGGAAAAATATATCTAGCTAATTTCCCAGAAACAACCAAACCCTGAAAATTCCTTGGGCTAT
ATATATGTGAGTTAAATCCT

Downstream 100 bases:

>100_bases
AAATCTCCACCAAGTTTCTCACAGGTTCTACTATATCTGTCGGACTCATAGTGGCTATTCTTATCGGCAATACTGTAGTT
GTGCAGCAAATTAGGCAGAA

Product: hypothetical protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKKAMQWLISRKMLFSSQLVVVTAIACILSIGCHNSISSKNQPLVNKTSSQLATDDIRVVRRTRERQGTVYDNTSVSSVS
RNVLPKLKIGLLSTQNFTEQQQIIKPLNDYLETSLGRQVHFFIAKDHEEIIEWLTQDKLDLAYLGSVAYLEAVDRGAEIQ
PLVTSIDKHTGQPWYRACIIVKADSSIKTLKDLKGKRVAFVDKSSTSGYLMPLVALSKQSIDPQKDFRTVIYAGNHRKSI
AALENGSVDAAATNVSSYITFKKSGKLTPQDYRLIWESAPIPNFPIVISQKLAPELIQQLKQVFISTPEGMKDILGAESA
GYTLVGPDHYAPIQQLRQELNLTSIPKK

Sequences:

>Translated_348_residues
MKKAMQWLISRKMLFSSQLVVVTAIACILSIGCHNSISSKNQPLVNKTSSQLATDDIRVVRRTRERQGTVYDNTSVSSVS
RNVLPKLKIGLLSTQNFTEQQQIIKPLNDYLETSLGRQVHFFIAKDHEEIIEWLTQDKLDLAYLGSVAYLEAVDRGAEIQ
PLVTSIDKHTGQPWYRACIIVKADSSIKTLKDLKGKRVAFVDKSSTSGYLMPLVALSKQSIDPQKDFRTVIYAGNHRKSI
AALENGSVDAAATNVSSYITFKKSGKLTPQDYRLIWESAPIPNFPIVISQKLAPELIQQLKQVFISTPEGMKDILGAESA
GYTLVGPDHYAPIQQLRQELNLTSIPKK
>Mature_348_residues
MKKAMQWLISRKMLFSSQLVVVTAIACILSIGCHNSISSKNQPLVNKTSSQLATDDIRVVRRTRERQGTVYDNTSVSSVS
RNVLPKLKIGLLSTQNFTEQQQIIKPLNDYLETSLGRQVHFFIAKDHEEIIEWLTQDKLDLAYLGSVAYLEAVDRGAEIQ
PLVTSIDKHTGQPWYRACIIVKADSSIKTLKDLKGKRVAFVDKSSTSGYLMPLVALSKQSIDPQKDFRTVIYAGNHRKSI
AALENGSVDAAATNVSSYITFKKSGKLTPQDYRLIWESAPIPNFPIVISQKLAPELIQQLKQVFISTPEGMKDILGAESA
GYTLVGPDHYAPIQQLRQELNLTSIPKK

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790543, Length=236, Percent_Identity=33.4745762711864, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 38789; Mature: 38789

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAMQWLISRKMLFSSQLVVVTAIACILSIGCHNSISSKNQPLVNKTSSQLATDDIRVV
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RRTRERQGTVYDNTSVSSVSRNVLPKLKIGLLSTQNFTEQQQIIKPLNDYLETSLGRQVH
HHHHHHCCCEECCCCHHHHHHHCCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEE
FFIAKDHEEIIEWLTQDKLDLAYLGSVAYLEAVDRGAEIQPLVTSIDKHTGQPWYRACII
EEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHEEEEE
VKADSSIKTLKDLKGKRVAFVDKSSTSGYLMPLVALSKQSIDPQKDFRTVIYAGNHRKSI
EECCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCHHHCEEEEEECCCCCEE
AALENGSVDAAATNVSSYITFKKSGKLTPQDYRLIWESAPIPNFPIVISQKLAPELIQQL
EEECCCCCCHHHHCHHHEEEECCCCCCCCHHHEEEEECCCCCCCCEEECHHHHHHHHHHH
KQVFISTPEGMKDILGAESAGYTLVGPDHYAPIQQLRQELNLTSIPKK
HHHHHCCCCHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKKAMQWLISRKMLFSSQLVVVTAIACILSIGCHNSISSKNQPLVNKTSSQLATDDIRVV
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RRTRERQGTVYDNTSVSSVSRNVLPKLKIGLLSTQNFTEQQQIIKPLNDYLETSLGRQVH
HHHHHHCCCEECCCCHHHHHHHCCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEE
FFIAKDHEEIIEWLTQDKLDLAYLGSVAYLEAVDRGAEIQPLVTSIDKHTGQPWYRACII
EEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHEEEEE
VKADSSIKTLKDLKGKRVAFVDKSSTSGYLMPLVALSKQSIDPQKDFRTVIYAGNHRKSI
EECCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCHHHCEEEEEECCCCCEE
AALENGSVDAAATNVSSYITFKKSGKLTPQDYRLIWESAPIPNFPIVISQKLAPELIQQL
EEECCCCCCHHHHCHHHEEEECCCCCCCCHHHEEEEECCCCCCCCEEECHHHHHHHHHHH
KQVFISTPEGMKDILGAESAGYTLVGPDHYAPIQQLRQELNLTSIPKK
HHHHHCCCCHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]