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The map label for this gene is coxB [H]

Identifier: 17230223

GI number: 17230223

Start: 3328482

End: 3329396

Strand: Direct

Name: coxB [H]

Synonym: alr2731

Alternate gene names: 17230223

Gene position: 3328482-3329396 (Clockwise)

Preceding gene: 17230222

Following gene: 17230224

Centisome position: 51.9

GC content: 45.03

Gene sequence:

>915_bases
ATGACAATCAGTAAATTTTTCAACATTGTGACATTGGTAATAGGCGCGATCGCTGTGACTATTACCAGTTTCTGGATTGG
TAAACTGGCTTACACCTGGCTACCTCCCCAAGCGGCGGCTGAATCAATCTTAATTGATGATTTATTTAGCTTCTTGGTAA
CTATGGGTGCATTCATCTTCCTTGGTGTTACCTCCACTCTGTTCTATTCTTTACTATTCCATCGGGCGGCTGAAAACGAC
CTCAGCGATGGCCCCCACATTGAAGGTAATGTCACCTTAGAAGTGGTTTGGACAGCTATTCCTATCCTCTTAGTAGTTTG
GATTGCCACCTATAGCTACCAAATTTACGAACAAATGGGCATCCAAGGGCCGACAGCATTAGTACACCTGCATAACCCAA
TGGAGATGGAATCCGCCTATGCAGCCACAGAGGATGGTTTAGTTGAACCAGAAGAAAAAATTGATGTAATTGCTAAACAA
TGGGCGTGGGTATTCCACTATCCCGAAAAGAATGTTACCAGCACCGAGTTACATTTACCAAGCGATCGCCGGGTAAAATT
GGCGCTGCATTCTGAAGATGTACTCCACGGCTTCTATATTCCCGCCTTCCGCCTCAAGCAAGACATCATCCCCAACCACA
ACATCGACTTTGAATTTACCCCCATCCGTGAAGGTAAATATCATCTAACCGACTCTCAATATAGTGGTACATACTTCGCC
ACTATGCAAGCCAATGTAGTGGTGGAATCTCCTGAAGAGTATCACAAATGGTTAGCCAAAATAGCCACCCACAAACCTGG
CACTGCCTACAATCAAGCATCTGCTGAATATGCACAAAGCATCACTCAGCAAGTCAAAACTGGTTGGAAAACCGTAGCAC
CAGCCGCCGCACCTTTGGTTAATTACCCTGGTTAA

Upstream 100 bases:

>100_bases
TGCTGAATTTGGCGTACACAACACAGCAGATAGCTTGTTGCGATTAGGCGAAGACCTCAACACAGTCCTCAAGTAATTCT
AGAGTCTTTGACCACTAACC

Downstream 100 bases:

>100_bases
AAGCTCAACCCCTACACCACTACTATTTCACCAATGACCAACATCCCCATAGAAGGCGTTCAACTCCCTGAGGGGAAGCC
TCACCACCCATCTCCCGGAG

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTISKFFNIVTLVIGAIAVTITSFWIGKLAYTWLPPQAAAESILIDDLFSFLVTMGAFIFLGVTSTLFYSLLFHRAAEND
LSDGPHIEGNVTLEVVWTAIPILLVVWIATYSYQIYEQMGIQGPTALVHLHNPMEMESAYAATEDGLVEPEEKIDVIAKQ
WAWVFHYPEKNVTSTELHLPSDRRVKLALHSEDVLHGFYIPAFRLKQDIIPNHNIDFEFTPIREGKYHLTDSQYSGTYFA
TMQANVVVESPEEYHKWLAKIATHKPGTAYNQASAEYAQSITQQVKTGWKTVAPAAAPLVNYPG

Sequences:

>Translated_304_residues
MTISKFFNIVTLVIGAIAVTITSFWIGKLAYTWLPPQAAAESILIDDLFSFLVTMGAFIFLGVTSTLFYSLLFHRAAEND
LSDGPHIEGNVTLEVVWTAIPILLVVWIATYSYQIYEQMGIQGPTALVHLHNPMEMESAYAATEDGLVEPEEKIDVIAKQ
WAWVFHYPEKNVTSTELHLPSDRRVKLALHSEDVLHGFYIPAFRLKQDIIPNHNIDFEFTPIREGKYHLTDSQYSGTYFA
TMQANVVVESPEEYHKWLAKIATHKPGTAYNQASAEYAQSITQQVKTGWKTVAPAAAPLVNYPG
>Mature_303_residues
TISKFFNIVTLVIGAIAVTITSFWIGKLAYTWLPPQAAAESILIDDLFSFLVTMGAFIFLGVTSTLFYSLLFHRAAENDL
SDGPHIEGNVTLEVVWTAIPILLVVWIATYSYQIYEQMGIQGPTALVHLHNPMEMESAYAATEDGLVEPEEKIDVIAKQW
AWVFHYPEKNVTSTELHLPSDRRVKLALHSEDVLHGFYIPAFRLKQDIIPNHNIDFEFTPIREGKYHLTDSQYSGTYFAT
MQANVVVESPEEYHKWLAKIATHKPGTAYNQASAEYAQSITQQVKTGWKTVAPAAAPLVNYPG

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI1786635, Length=234, Percent_Identity=23.0769230769231, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 34125; Mature: 33994

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISKFFNIVTLVIGAIAVTITSFWIGKLAYTWLPPQAAAESILIDDLFSFLVTMGAFIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGVTSTLFYSLLFHRAAENDLSDGPHIEGNVTLEVVWTAIPILLVVWIATYSYQIYEQMG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHC
IQGPTALVHLHNPMEMESAYAATEDGLVEPEEKIDVIAKQWAWVFHYPEKNVTSTELHLP
CCCCEEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCEEEEECCCCCCCCCEEECC
SDRRVKLALHSEDVLHGFYIPAFRLKQDIIPNHNIDFEFTPIREGKYHLTDSQYSGTYFA
CCCEEEEEECCCCHHHHHCCCHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCCEEEE
TMQANVVVESPEEYHKWLAKIATHKPGTAYNQASAEYAQSITQQVKTGWKTVAPAAAPLV
EEEEEEEEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCHHCCCC
NYPG
CCCC
>Mature Secondary Structure 
TISKFFNIVTLVIGAIAVTITSFWIGKLAYTWLPPQAAAESILIDDLFSFLVTMGAFIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGVTSTLFYSLLFHRAAENDLSDGPHIEGNVTLEVVWTAIPILLVVWIATYSYQIYEQMG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHC
IQGPTALVHLHNPMEMESAYAATEDGLVEPEEKIDVIAKQWAWVFHYPEKNVTSTELHLP
CCCCEEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCEEEEECCCCCCCCCEEECC
SDRRVKLALHSEDVLHGFYIPAFRLKQDIIPNHNIDFEFTPIREGKYHLTDSQYSGTYFA
CCCEEEEEECCCCHHHHHCCCHHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCCCEEEE
TMQANVVVESPEEYHKWLAKIATHKPGTAYNQASAEYAQSITQQVKTGWKTVAPAAAPLV
EEEEEEEEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCHHCCCC
NYPG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8383492; 8387368; 8905231 [H]