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The map label for this gene is pabC [H]

Identifier: 17228755

GI number: 17228755

Start: 1494747

End: 1495538

Strand: Direct

Name: pabC [H]

Synonym: alr1260

Alternate gene names: 17228755

Gene position: 1494747-1495538 (Clockwise)

Preceding gene: 17228754

Following gene: 17228756

Centisome position: 23.31

GC content: 43.31

Gene sequence:

>792_bases
ATGTTCTGGTACAACGGTAAACTAATTAATTCCCAAACCTTGGAGTTAGATATCTATGATCCTGGGTTACTTTATGGGAC
AACTATTTTTACAACACTGCGAGTTTATGGCCATTCTCTCGATCATACTTTAACTAATTGGCAAGCACACTGCGATCGCC
TCCACGCCTCTATCCAATCTTTTGCTTGGGAACAACCAGACTGGAATCGTATCCGCCAAGGTGCAGAAATACTTTTAACA
AACTTCCCCGTTCTCAGAATCACCATCTTTCCTGATGGTAGGGAATGGATAATTGGCAGGTATTTACCCCAGAATTTATT
AGGAATCCAAAAACATGGCGTATCTTGCACCATTGCTGAACCAGAAATATATCGTAGTTTGCCTTCTCATAAAACTGGTA
ACTATCTGAGTGCATGGATGGCTAAAACCCATGCGGCAAAGCTAGATTCACAGGAAGCAATTTTAGTGAATACCGTCGGA
AATTGGCTAGAAACCACCACAGGCAACCTTTGGGGATGGCAGAATGGGACTTGGTGGACACCACCTTTAACAGAGGGAAT
TTTACCGGGGATTGGACGACAGCAGCTAATTCACTGGCTACAAACTCATCAACAAACGGTGCAGGAGGAACCTTGGACAT
CAGAGCTAGTCAACGGTTTTGAAGCGATCGCCTACACTAATAGTGTGGTGGAAGTTATTCCCATACATACCGTTTACCAA
CCCACAGAATCGTTACAATATGATCCCTACCATCCACGTTTGCAGGAACTCAGAAAACTATTCTTAGCATGA

Upstream 100 bases:

>100_bases
GATTAGTTATTGGTAATTGCTCAATAGTTTTATTCTTCTTTGCACCCCAGTCCCCAATCCCCAGTCCCCAGTCCCCAGTC
CCCAATCCCCAACCCCCAAG

Downstream 100 bases:

>100_bases
CAGATGTATCATTTTGGTATAGGTTAAGATAAGTTAACATAATTCTAATAATGCCCTACGCACAAAAATACGGGAGGATA
AACCTCGGTGAATAAAAGAT

Product: hypothetical protein

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MFWYNGKLINSQTLELDIYDPGLLYGTTIFTTLRVYGHSLDHTLTNWQAHCDRLHASIQSFAWEQPDWNRIRQGAEILLT
NFPVLRITIFPDGREWIIGRYLPQNLLGIQKHGVSCTIAEPEIYRSLPSHKTGNYLSAWMAKTHAAKLDSQEAILVNTVG
NWLETTTGNLWGWQNGTWWTPPLTEGILPGIGRQQLIHWLQTHQQTVQEEPWTSELVNGFEAIAYTNSVVEVIPIHTVYQ
PTESLQYDPYHPRLQELRKLFLA

Sequences:

>Translated_263_residues
MFWYNGKLINSQTLELDIYDPGLLYGTTIFTTLRVYGHSLDHTLTNWQAHCDRLHASIQSFAWEQPDWNRIRQGAEILLT
NFPVLRITIFPDGREWIIGRYLPQNLLGIQKHGVSCTIAEPEIYRSLPSHKTGNYLSAWMAKTHAAKLDSQEAILVNTVG
NWLETTTGNLWGWQNGTWWTPPLTEGILPGIGRQQLIHWLQTHQQTVQEEPWTSELVNGFEAIAYTNSVVEVIPIHTVYQ
PTESLQYDPYHPRLQELRKLFLA
>Mature_263_residues
MFWYNGKLINSQTLELDIYDPGLLYGTTIFTTLRVYGHSLDHTLTNWQAHCDRLHASIQSFAWEQPDWNRIRQGAEILLT
NFPVLRITIFPDGREWIIGRYLPQNLLGIQKHGVSCTIAEPEIYRSLPSHKTGNYLSAWMAKTHAAKLDSQEAILVNTVG
NWLETTTGNLWGWQNGTWWTPPLTEGILPGIGRQQLIHWLQTHQQTVQEEPWTSELVNGFEAIAYTNSVVEVIPIHTVYQ
PTESLQYDPYHPRLQELRKLFLA

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 30347; Mature: 30347

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFWYNGKLINSQTLELDIYDPGLLYGTTIFTTLRVYGHSLDHTLTNWQAHCDRLHASIQS
CEEECCEEECCEEEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
FAWEQPDWNRIRQGAEILLTNFPVLRITIFPDGREWIIGRYLPQNLLGIQKHGVSCTIAE
HCCCCCCHHHHHCCHHEEEECCCEEEEEECCCCCEEEEEHHCCHHHHHHHHCCCEEEEEC
PEIYRSLPSHKTGNYLSAWMAKTHAAKLDSQEAILVNTVGNWLETTTGNLWGWQNGTWWT
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCEECCCCCCEEC
PPLTEGILPGIGRQQLIHWLQTHQQTVQEEPWTSELVNGFEAIAYTNSVVEVIPIHTVYQ
CCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCEEEC
PTESLQYDPYHPRLQELRKLFLA
CHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MFWYNGKLINSQTLELDIYDPGLLYGTTIFTTLRVYGHSLDHTLTNWQAHCDRLHASIQS
CEEECCEEECCEEEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
FAWEQPDWNRIRQGAEILLTNFPVLRITIFPDGREWIIGRYLPQNLLGIQKHGVSCTIAE
HCCCCCCHHHHHCCHHEEEECCCEEEEEECCCCCEEEEEHHCCHHHHHHHHCCCEEEEEC
PEIYRSLPSHKTGNYLSAWMAKTHAAKLDSQEAILVNTVGNWLETTTGNLWGWQNGTWWT
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCCEECCCCCCEEC
PPLTEGILPGIGRQQLIHWLQTHQQTVQEEPWTSELVNGFEAIAYTNSVVEVIPIHTVYQ
CCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCEEEC
PTESLQYDPYHPRLQELRKLFLA
CHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]