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The map label for this gene is cobC [H]

Identifier: 17228602

GI number: 17228602

Start: 1295920

End: 1296558

Strand: Direct

Name: cobC [H]

Synonym: alr1107

Alternate gene names: 17228602

Gene position: 1295920-1296558 (Clockwise)

Preceding gene: 17228600

Following gene: 17228603

Centisome position: 20.21

GC content: 42.41

Gene sequence:

>639_bases
GTGAGCCTAAATCTTTATTTACTTCGTCACGGACAAACAGAATGCAGCCGTAATAATGCCTTTTGCGGTTCAATCGACTC
ATCACTGACCCCAGAAGGTTTGGAAATGGCAAAAGCTTTTGCGTCTACCTATAGTTCAGTCTCTTGGACAGCTATTTTTT
CCAGTCCCATGCAGCGAACTATGGACACAGCCAAACCTTTAAGTGAAGCAATAGGAATTAAACCAGAACTGCGGGATGGT
TTAAAAGAAATTAATTACGGCCAATGGGAAGGCAAAACCCCAAAACAAATCAACCAAGAATACCACGATGATTATATTCG
CTGGTCGGCTGACCCTGCGTGGTATGCTCCTACTGGCGGAGAAATGGCTATCACAATTGCATCTCGCGCTATGGGAGTAA
TTGAAGAAATTAAACATCTGTATACTAGTGGCAATGTTTTGGTAGTTTCTCACAAAGCCACCATTAGAATTATTTTGTGC
AGTCTGTTAGGAATTGATGTTGGACGTTTTCGCTATCGTTTAGGATGTCCAGTCGCTTCAGTTAGTCTTGTAGAATTTAC
TGCTCACGGCCCCATTTTACAGATGTTAGCCGATCGCACTCATTTAAATGAGCATTTACGCAACTTAGCGGGAACGTAA

Upstream 100 bases:

>100_bases
TTGTGTTCCGCCCACTGTGCTTTCTAATACCCAGGTTAGCCGTCCACAGACATTAACTAATTGTTCGCATTCTGACATTG
AAAATAAGTGAGAATCAAAA

Downstream 100 bases:

>100_bases
ACTAATCCCCAGTCCCCATTTTCCATACAACAGGGCAGCAATGGCTAATAATATAAGAAGGCGCTTCACACTTCTTAATT
ATTTAGTTTTACTATGGCCA

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSLNLYLLRHGQTECSRNNAFCGSIDSSLTPEGLEMAKAFASTYSSVSWTAIFSSPMQRTMDTAKPLSEAIGIKPELRDG
LKEINYGQWEGKTPKQINQEYHDDYIRWSADPAWYAPTGGEMAITIASRAMGVIEEIKHLYTSGNVLVVSHKATIRIILC
SLLGIDVGRFRYRLGCPVASVSLVEFTAHGPILQMLADRTHLNEHLRNLAGT

Sequences:

>Translated_212_residues
MSLNLYLLRHGQTECSRNNAFCGSIDSSLTPEGLEMAKAFASTYSSVSWTAIFSSPMQRTMDTAKPLSEAIGIKPELRDG
LKEINYGQWEGKTPKQINQEYHDDYIRWSADPAWYAPTGGEMAITIASRAMGVIEEIKHLYTSGNVLVVSHKATIRIILC
SLLGIDVGRFRYRLGCPVASVSLVEFTAHGPILQMLADRTHLNEHLRNLAGT
>Mature_211_residues
SLNLYLLRHGQTECSRNNAFCGSIDSSLTPEGLEMAKAFASTYSSVSWTAIFSSPMQRTMDTAKPLSEAIGIKPELRDGL
KEINYGQWEGKTPKQINQEYHDDYIRWSADPAWYAPTGGEMAITIASRAMGVIEEIKHLYTSGNVLVVSHKATIRIILCS
LLGIDVGRFRYRLGCPVASVSLVEFTAHGPILQMLADRTHLNEHLRNLAGT

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Homo sapiens, GI4758902, Length=189, Percent_Identity=30.6878306878307, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI118582286, Length=189, Percent_Identity=30.6878306878307, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI64762406, Length=190, Percent_Identity=29.4736842105263, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI64762445, Length=190, Percent_Identity=29.4736842105263, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786857, Length=177, Percent_Identity=25.9887005649718, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1790856, Length=209, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 23491; Mature: 23360

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNLYLLRHGQTECSRNNAFCGSIDSSLTPEGLEMAKAFASTYSSVSWTAIFSSPMQRT
CCEEEEEEECCCCHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
MDTAKPLSEAIGIKPELRDGLKEINYGQWEGKTPKQINQEYHDDYIRWSADPAWYAPTGG
HHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEECCCCCEECCCCC
EMAITIASRAMGVIEEIKHLYTSGNVLVVSHKATIRIILCSLLGIDVGRFRYRLGCPVAS
CEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCHHHHHHECCCCCHH
VSLVEFTAHGPILQMLADRTHLNEHLRNLAGT
HHHEEECCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLNLYLLRHGQTECSRNNAFCGSIDSSLTPEGLEMAKAFASTYSSVSWTAIFSSPMQRT
CEEEEEEECCCCHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
MDTAKPLSEAIGIKPELRDGLKEINYGQWEGKTPKQINQEYHDDYIRWSADPAWYAPTGG
HHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEECCCCCEECCCCC
EMAITIASRAMGVIEEIKHLYTSGNVLVVSHKATIRIILCSLLGIDVGRFRYRLGCPVAS
CEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCHHHHHHECCCCCHH
VSLVEFTAHGPILQMLADRTHLNEHLRNLAGT
HHHEEECCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]