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The map label for this gene is gap3 [H]

Identifier: 17228590

GI number: 17228590

Start: 1283199

End: 1284212

Strand: Direct

Name: gap3 [H]

Synonym: alr1095

Alternate gene names: 17228590

Gene position: 1283199-1284212 (Clockwise)

Preceding gene: 17228589

Following gene: 17228591

Centisome position: 20.01

GC content: 47.24

Gene sequence:

>1014_bases
ATGAAAGTTCGTGTTGGTATCAACGGATTTGGTAGGATGGGGCGGCTGGCTTTGCGGGCTGCATGGGATTGGCCGGAACT
GGAATTTGTGCATATTAATGAAATAAAAGGTGGTGCAGTTGCAGCAGCCCATTTGCTCAAATTTGATTCTGTTCACGGAC
GCTGGACACCAGAGGTAGAAGCAGAGGGGGAACGTGTCCTGATTGATGGTACTCCCCTGAGTTTTAGTGAGTATGGCAAA
CCAGACGATGTACCCTGGGAAGACTTTGGTGTTGATTTAGTCCTAGAATGTTCTGGCAAATTTCGGACTCCTGCAACCCT
CGACCCCTATTTCAAGCGCGGGGTGCAGAAGGTAATTGTGGCTGCACCTGTGAAGGAAGAAGCCTTAAATATTGTCATGG
GAGTGAATGACTATTTATATGAGCCGGAAAAGCATCATCTTTTAACTGCTGCTTCCTGTACAACCAACTGTTTAGCCCCA
GTGGTGAAAGTGATTCATGAAGGTTTGGGGATTAAACATGGAATTATTACCACCATCCATGACAACACCAATACTCAAAC
CCTCGTTGATGCGCCCCACAAAGATTTACGGCGCGCACGGGCTACCAGTTTATCACTGATTCCGACCACTACAGGATCAG
CAACAGCGATCGCCTTAATTTACCCAGAACTCAAAGGTAAACTCAACGGTATCGCTGTACGAGTACCACTGCTCAACGCT
TCCCTCACAGACTGTGTGTTTGAAGTTACCCGACCAACCACAGTCGAAGAAATTAACGCACTCCTCAAAGCTGCATCTGA
ACAAGCACCACTCCAAGGCATCCTGGGCTATGAAGAACGTCCTTTAGTCTCCATCGACTACAAAGATGACCCTCGTTCTT
CCATCATTGATGCCCTTTCCACAATGGTTGTAGACGAAACGCAAGTGAAAATTCTGGCTTGGTATGACAACGAGTGGGGT
TACGTCAACCGCATGGTTGAACTCGCTCGTAAGGTTGCATTAAGTCTCAAATAG

Upstream 100 bases:

>100_bases
AACGCTTAGTGAATTACTACGCAAGCAAAAGCAATTTTAATAAATAGTTAACAGTTGACTGTTGACTGTTGACTGTTGAC
TAATAAAAATAGGAAAACGC

Downstream 100 bases:

>100_bases
GGATTGGGTATCAGGTATCGGGGACTAGGTATTAGCTCAAAAGTAAATCCCCCAGTTCCCAATCCTCAGTCCCCAGTCCC
CAGTCCCCAATCCCCAGTCC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKVRVGINGFGRMGRLALRAAWDWPELEFVHINEIKGGAVAAAHLLKFDSVHGRWTPEVEAEGERVLIDGTPLSFSEYGK
PDDVPWEDFGVDLVLECSGKFRTPATLDPYFKRGVQKVIVAAPVKEEALNIVMGVNDYLYEPEKHHLLTAASCTTNCLAP
VVKVIHEGLGIKHGIITTIHDNTNTQTLVDAPHKDLRRARATSLSLIPTTTGSATAIALIYPELKGKLNGIAVRVPLLNA
SLTDCVFEVTRPTTVEEINALLKAASEQAPLQGILGYEERPLVSIDYKDDPRSSIIDALSTMVVDETQVKILAWYDNEWG
YVNRMVELARKVALSLK

Sequences:

>Translated_337_residues
MKVRVGINGFGRMGRLALRAAWDWPELEFVHINEIKGGAVAAAHLLKFDSVHGRWTPEVEAEGERVLIDGTPLSFSEYGK
PDDVPWEDFGVDLVLECSGKFRTPATLDPYFKRGVQKVIVAAPVKEEALNIVMGVNDYLYEPEKHHLLTAASCTTNCLAP
VVKVIHEGLGIKHGIITTIHDNTNTQTLVDAPHKDLRRARATSLSLIPTTTGSATAIALIYPELKGKLNGIAVRVPLLNA
SLTDCVFEVTRPTTVEEINALLKAASEQAPLQGILGYEERPLVSIDYKDDPRSSIIDALSTMVVDETQVKILAWYDNEWG
YVNRMVELARKVALSLK
>Mature_337_residues
MKVRVGINGFGRMGRLALRAAWDWPELEFVHINEIKGGAVAAAHLLKFDSVHGRWTPEVEAEGERVLIDGTPLSFSEYGK
PDDVPWEDFGVDLVLECSGKFRTPATLDPYFKRGVQKVIVAAPVKEEALNIVMGVNDYLYEPEKHHLLTAASCTTNCLAP
VVKVIHEGLGIKHGIITTIHDNTNTQTLVDAPHKDLRRARATSLSLIPTTTGSATAIALIYPELKGKLNGIAVRVPLLNA
SLTDCVFEVTRPTTVEEINALLKAASEQAPLQGILGYEERPLVSIDYKDDPRSSIIDALSTMVVDETQVKILAWYDNEWG
YVNRMVELARKVALSLK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=333, Percent_Identity=39.9399399399399, Blast_Score=261, Evalue=6e-70,
Organism=Homo sapiens, GI7657116, Length=327, Percent_Identity=39.4495412844037, Blast_Score=246, Evalue=2e-65,
Organism=Escherichia coli, GI1788079, Length=329, Percent_Identity=39.8176291793313, Blast_Score=258, Evalue=4e-70,
Organism=Escherichia coli, GI1789295, Length=331, Percent_Identity=38.9728096676737, Blast_Score=248, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=38.4615384615385, Blast_Score=245, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=38.7573964497041, Blast_Score=245, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17568413, Length=338, Percent_Identity=38.7573964497041, Blast_Score=245, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=38.1656804733728, Blast_Score=244, Evalue=5e-65,
Organism=Saccharomyces cerevisiae, GI6321631, Length=332, Percent_Identity=41.2650602409639, Blast_Score=266, Evalue=4e-72,
Organism=Saccharomyces cerevisiae, GI6322468, Length=332, Percent_Identity=40.3614457831325, Blast_Score=265, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6322409, Length=332, Percent_Identity=39.7590361445783, Blast_Score=262, Evalue=5e-71,
Organism=Drosophila melanogaster, GI85725000, Length=328, Percent_Identity=39.6341463414634, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI22023983, Length=328, Percent_Identity=39.6341463414634, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=36.3076923076923, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI17933600, Length=328, Percent_Identity=38.719512195122, Blast_Score=241, Evalue=7e-64,
Organism=Drosophila melanogaster, GI18110149, Length=328, Percent_Identity=38.719512195122, Blast_Score=241, Evalue=7e-64,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37117; Mature: 37117

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRVGINGFGRMGRLALRAAWDWPELEFVHINEIKGGAVAAAHLLKFDSVHGRWTPEVE
CEEEEECCCCCCHHHEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCC
AEGERVLIDGTPLSFSEYGKPDDVPWEDFGVDLVLECSGKFRTPATLDPYFKRGVQKVIV
CCCCEEEEECCCCCHHHCCCCCCCCHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHEEE
AAPVKEEALNIVMGVNDYLYEPEKHHLLTAASCTTNCLAPVVKVIHEGLGIKHGIITTIH
ECCCHHHHEEEEECCHHHHCCCCHHCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
DNTNTQTLVDAPHKDLRRARATSLSLIPTTTGSATAIALIYPELKGKLNGIAVRVPLLNA
CCCCCEEEEECCHHHHHHHHHCCEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEEECCC
SLTDCVFEVTRPTTVEEINALLKAASEQAPLQGILGYEERPLVSIDYKDDPRSSIIDALS
CHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEECCCCCHHHHHHHHH
TMVVDETQVKILAWYDNEWGYVNRMVELARKVALSLK
HHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVRVGINGFGRMGRLALRAAWDWPELEFVHINEIKGGAVAAAHLLKFDSVHGRWTPEVE
CEEEEECCCCCCHHHEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCC
AEGERVLIDGTPLSFSEYGKPDDVPWEDFGVDLVLECSGKFRTPATLDPYFKRGVQKVIV
CCCCEEEEECCCCCHHHCCCCCCCCHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHEEE
AAPVKEEALNIVMGVNDYLYEPEKHHLLTAASCTTNCLAPVVKVIHEGLGIKHGIITTIH
ECCCHHHHEEEEECCHHHHCCCCHHCEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
DNTNTQTLVDAPHKDLRRARATSLSLIPTTTGSATAIALIYPELKGKLNGIAVRVPLLNA
CCCCCEEEEECCHHHHHHHHHCCEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEEECCC
SLTDCVFEVTRPTTVEEINALLKAASEQAPLQGILGYEERPLVSIDYKDDPRSSIIDALS
CHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEECCCCCHHHHHHHHH
TMVVDETQVKILAWYDNEWGYVNRMVELARKVALSLK
HHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]