Click here to switch to the map view.

The map label for this gene is ileS

Identifier: 17228568

GI number: 17228568

Start: 1254612

End: 1257494

Strand: Direct

Name: ileS

Synonym: alr1073

Alternate gene names: 17228568

Gene position: 1254612-1257494 (Clockwise)

Preceding gene: 17228562

Following gene: 17228569

Centisome position: 19.56

GC content: 46.55

Gene sequence:

>2883_bases
GTGACGGAAACTGGAAGTTACAAAGATACCGTAAATTTACCCAAGACCAATTTTGATATGCGGGCGAACGCCATTAAGCG
GGAACCCGAAATCCAAAAGTTTTGGGAAGAAAATAAAATTTTTGAGAGCCTGTCGCAAAACAACCCAGGTGAATTATTTA
TACTGCACGATGGGCCTCCCTACGCTAACGGCTCACTCCATATTGGTCATGCCTTAAATAAAATTCTCAAAGATATTATT
AATCGTTACCAACTGCTGCAAGGTCGAAAGGTTCGCTATGTACCCGGTTGGGACTGTCACGGCTTACCAATTGAGTTGAA
AGTTTTGCAAAATCTCAAGTCAGCAGAACGGCAAAATTTAACACCACTACAACTGCGGCAAAAGGCTAAAGAGTTTGCTT
TGGCTACGGTTGATAACCAACGCCAAAATTTTAAACGTTATGGTGTTTGGGGTGACTGGGATAATCCATATCTGACGCTA
AAGCCGGAATATGAGGCGGCGCAGATTGGTGTATTTGGGCAGATGGTTTTAAAAGGCTACATTTATCGGGGTTTGAAGCC
TGTTCACTGGAGTCCTAGTTCTAAGACGGCTTTGGCTGAGGCGGAATTGGAATATCCAGAAGGTCATACTTCCCGGAGTA
TCTATGCGGCTTTTCCTGTGACTAGTTTCGCTGAGGCGGCAAAACCTTTATTAGGTGAGTATTTGCCTGATTTGGGTGTG
GCTATCTGGACTACTACACCTTGGACAATTCCGGGGAATTTGGCGGTGGCTGTCAATGGCGACTTGAATTATTCTTTGGT
GGAAGTTTCGCGCATAGGCGCAGAGACGCAAAGTAATTTCAAGTATCTCATCGTGGCGGCCGATTTGGTAGAACGGTTGG
CGGCGACTATCTCGGCGCAGTTGACTGTGAAGGCGACTTTTAAAGGGAAGGAGTTGGAACATACTACTTACCGTCATCCT
TTATTTGATAGAGAAAGTCCGGTGGTTGTGGGTGGTGATTACATCACAACTGAATCGGGTACTGGGTTGGTACATACTGC
GCCCGGTCATGGTCAAGAAGACTATGTTGTGGGTCTGCGTTATGGGTTGCCAATTCTTGCACCTGTGGACGACAACGGCG
ACTTTACCCAAGAGGCGGGACAGTTTGCGGGGTTGAATGTGTTGGGTGAGGGAAATCAGGCGGTCATTGATGCGTTGACT
GCTGCGGGTTCCCTGTTGAAGGAGGAAGCTTATGCACACAAGTATCCTTATGATTGGCGGACGAAGAAGCCGACAATTTT
CCGGGCGACTGAACAGTGGTTTGCTTCGGTGGAGGGTTTCCGGGATGAGGCACTAAAGGCGATCGCTGCTGTAAAATGGA
TACCAGCCCAAGGTGAAAATCGCATCACGCCGATGGTGGCGGAACGTTCTGACTGGTGTATTTCTCGTCAGCGTTCTTGG
GGTGTGCCGATTCCGGTATTCTACGATGAGGAAACCGGCGAACCTCTACTAAATGAGGAAACTATCAACTATGTGCAAGC
CATCATTGCCGAAAAAGGTTCTGATGCTTGGTGGGAGTTGTCGGTAGCGGAATTATTACCGGAGTCCTACAGAAATAATG
GTCGGTCTTACCGCAGAGGTACAGACACAATGGACGTATGGTTTGATTCTGGTTCTTCTTGGGCTTCTGTAGTTAAGCAG
CGTCCAGAGTTACGCTACCCGGCTGATATGTATTTGGAAGGTTCCGACCAGCATCGCGGCTGGTTCCAGTCGAGTTTGTT
GACTAGTGTGTCAGTAAATGGCATTGCACCTTACAAAACTGTATTAACTCACGGCTTTGTTTTGGATGAACAAGGGCGGA
AGATGAGTAAATCAGAAGGGAATGTAGTTGACCCGGCTATTATCATCAATGGTGGTAAAGACCAGAAGAAAGAACCCCCC
TATGGTGCAGATGTTATGCGGTTGTGGGCTTCTTCTGTAGATTACACCGGGGATGTGCGTTTGGGTGGCAATATCATCAA
GCAACTCAACGATGTCAGAGGTAAGATTCGCAATACGGCGCGGTTCTTACTGGGTAGTTTGTATGACTTTGACCCAGAAA
AAAACGCTGTACAGTTTGAAGAAATGCCGCAGTTAGATAAGTATATGCTGCACCGTATCCGTGAAGTGTTTGAGGAAGTG
ACAGAAGCTTTTGAAAGTTTCCAATTCTTCCGCTTCTTCCAAACGGTGCAGAATTTCTGCGTGGTAGATTTATCTAACTT
CTACTTAGATGTTGCCAAGGATAGACTATATATCAGCGCCCCTGATGCTTTCCGCCGTCGCAGTTGTCAGACAGTGATAC
ACATTGCTTTAGAGAATTTAGCACGAGCGATCGCACCTGTACTCTGTCACACGGCAGAAGATATCTGGCAATATCTCCCC
TACAAAACACCCTACAAATCAGTGTTTGAAGCTGGTTGGGTGCAGGTAGAAGAAAAATGGCATAATCCAGAGTTGGCGGA
ATTTTGGCAACAATTACGCCAGTTACGCACCGATGTTAACAAGGTGTTAGAACAAGCTAGGGTAGAGAAAATGATTGGTT
CTTCCCTAGAAGCGAAAGCTTTGATTTACGTCAAAGATGCCAACTCCCGCAAAGCCATCGCCACGTTAAATCCTGAAGTT
GGTAACGGCGTGGATGAACTGCGTTATTTATTCTTGACATCCCAAGTAGAGTTATTAGATTCTGCTGACAAACTGCAAGA
TGGGAAATATACCTCCCAGTCTGATAGTTGGGGAATTGGGGTAGTGAATGCAGAGGGGCAAAAATGCGATCGCTGTTGGA
ACTACTCCACCCATGTGGGAGAATCAGCAGAGCATCCCCTGTTATGTGAAAGATGCGTTCCTGCCTTAGCTGGTGAGTTT
TAG

Upstream 100 bases:

>100_bases
TTAAGTAGCCAGGATGGGATGAGCAAAAGAGGTAATTTTGGGATTCATGCCATCTTCTATAATTGATAGAACCTGCATAT
ATAATCTTAGGCATGAAGCT

Downstream 100 bases:

>100_bases
AACAGGTTTAACATGAATGTAGGGACGTTTTATTCAACGTCTCTACGTCAAAATTCAGATGGGATTATGAACACGCAATC
ACCTGTAGCCACAGACATCT

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 960; Mature: 959

Protein sequence:

>960_residues
MTETGSYKDTVNLPKTNFDMRANAIKREPEIQKFWEENKIFESLSQNNPGELFILHDGPPYANGSLHIGHALNKILKDII
NRYQLLQGRKVRYVPGWDCHGLPIELKVLQNLKSAERQNLTPLQLRQKAKEFALATVDNQRQNFKRYGVWGDWDNPYLTL
KPEYEAAQIGVFGQMVLKGYIYRGLKPVHWSPSSKTALAEAELEYPEGHTSRSIYAAFPVTSFAEAAKPLLGEYLPDLGV
AIWTTTPWTIPGNLAVAVNGDLNYSLVEVSRIGAETQSNFKYLIVAADLVERLAATISAQLTVKATFKGKELEHTTYRHP
LFDRESPVVVGGDYITTESGTGLVHTAPGHGQEDYVVGLRYGLPILAPVDDNGDFTQEAGQFAGLNVLGEGNQAVIDALT
AAGSLLKEEAYAHKYPYDWRTKKPTIFRATEQWFASVEGFRDEALKAIAAVKWIPAQGENRITPMVAERSDWCISRQRSW
GVPIPVFYDEETGEPLLNEETINYVQAIIAEKGSDAWWELSVAELLPESYRNNGRSYRRGTDTMDVWFDSGSSWASVVKQ
RPELRYPADMYLEGSDQHRGWFQSSLLTSVSVNGIAPYKTVLTHGFVLDEQGRKMSKSEGNVVDPAIIINGGKDQKKEPP
YGADVMRLWASSVDYTGDVRLGGNIIKQLNDVRGKIRNTARFLLGSLYDFDPEKNAVQFEEMPQLDKYMLHRIREVFEEV
TEAFESFQFFRFFQTVQNFCVVDLSNFYLDVAKDRLYISAPDAFRRRSCQTVIHIALENLARAIAPVLCHTAEDIWQYLP
YKTPYKSVFEAGWVQVEEKWHNPELAEFWQQLRQLRTDVNKVLEQARVEKMIGSSLEAKALIYVKDANSRKAIATLNPEV
GNGVDELRYLFLTSQVELLDSADKLQDGKYTSQSDSWGIGVVNAEGQKCDRCWNYSTHVGESAEHPLLCERCVPALAGEF

Sequences:

>Translated_960_residues
MTETGSYKDTVNLPKTNFDMRANAIKREPEIQKFWEENKIFESLSQNNPGELFILHDGPPYANGSLHIGHALNKILKDII
NRYQLLQGRKVRYVPGWDCHGLPIELKVLQNLKSAERQNLTPLQLRQKAKEFALATVDNQRQNFKRYGVWGDWDNPYLTL
KPEYEAAQIGVFGQMVLKGYIYRGLKPVHWSPSSKTALAEAELEYPEGHTSRSIYAAFPVTSFAEAAKPLLGEYLPDLGV
AIWTTTPWTIPGNLAVAVNGDLNYSLVEVSRIGAETQSNFKYLIVAADLVERLAATISAQLTVKATFKGKELEHTTYRHP
LFDRESPVVVGGDYITTESGTGLVHTAPGHGQEDYVVGLRYGLPILAPVDDNGDFTQEAGQFAGLNVLGEGNQAVIDALT
AAGSLLKEEAYAHKYPYDWRTKKPTIFRATEQWFASVEGFRDEALKAIAAVKWIPAQGENRITPMVAERSDWCISRQRSW
GVPIPVFYDEETGEPLLNEETINYVQAIIAEKGSDAWWELSVAELLPESYRNNGRSYRRGTDTMDVWFDSGSSWASVVKQ
RPELRYPADMYLEGSDQHRGWFQSSLLTSVSVNGIAPYKTVLTHGFVLDEQGRKMSKSEGNVVDPAIIINGGKDQKKEPP
YGADVMRLWASSVDYTGDVRLGGNIIKQLNDVRGKIRNTARFLLGSLYDFDPEKNAVQFEEMPQLDKYMLHRIREVFEEV
TEAFESFQFFRFFQTVQNFCVVDLSNFYLDVAKDRLYISAPDAFRRRSCQTVIHIALENLARAIAPVLCHTAEDIWQYLP
YKTPYKSVFEAGWVQVEEKWHNPELAEFWQQLRQLRTDVNKVLEQARVEKMIGSSLEAKALIYVKDANSRKAIATLNPEV
GNGVDELRYLFLTSQVELLDSADKLQDGKYTSQSDSWGIGVVNAEGQKCDRCWNYSTHVGESAEHPLLCERCVPALAGEF
>Mature_959_residues
TETGSYKDTVNLPKTNFDMRANAIKREPEIQKFWEENKIFESLSQNNPGELFILHDGPPYANGSLHIGHALNKILKDIIN
RYQLLQGRKVRYVPGWDCHGLPIELKVLQNLKSAERQNLTPLQLRQKAKEFALATVDNQRQNFKRYGVWGDWDNPYLTLK
PEYEAAQIGVFGQMVLKGYIYRGLKPVHWSPSSKTALAEAELEYPEGHTSRSIYAAFPVTSFAEAAKPLLGEYLPDLGVA
IWTTTPWTIPGNLAVAVNGDLNYSLVEVSRIGAETQSNFKYLIVAADLVERLAATISAQLTVKATFKGKELEHTTYRHPL
FDRESPVVVGGDYITTESGTGLVHTAPGHGQEDYVVGLRYGLPILAPVDDNGDFTQEAGQFAGLNVLGEGNQAVIDALTA
AGSLLKEEAYAHKYPYDWRTKKPTIFRATEQWFASVEGFRDEALKAIAAVKWIPAQGENRITPMVAERSDWCISRQRSWG
VPIPVFYDEETGEPLLNEETINYVQAIIAEKGSDAWWELSVAELLPESYRNNGRSYRRGTDTMDVWFDSGSSWASVVKQR
PELRYPADMYLEGSDQHRGWFQSSLLTSVSVNGIAPYKTVLTHGFVLDEQGRKMSKSEGNVVDPAIIINGGKDQKKEPPY
GADVMRLWASSVDYTGDVRLGGNIIKQLNDVRGKIRNTARFLLGSLYDFDPEKNAVQFEEMPQLDKYMLHRIREVFEEVT
EAFESFQFFRFFQTVQNFCVVDLSNFYLDVAKDRLYISAPDAFRRRSCQTVIHIALENLARAIAPVLCHTAEDIWQYLPY
KTPYKSVFEAGWVQVEEKWHNPELAEFWQQLRQLRTDVNKVLEQARVEKMIGSSLEAKALIYVKDANSRKAIATLNPEVG
NGVDELRYLFLTSQVELLDSADKLQDGKYTSQSDSWGIGVVNAEGQKCDRCWNYSTHVGESAEHPLLCERCVPALAGEF

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily

Homologues:

Organism=Homo sapiens, GI46852147, Length=987, Percent_Identity=40.1215805471125, Blast_Score=756, Evalue=0.0,
Organism=Homo sapiens, GI94721239, Length=810, Percent_Identity=30.2469135802469, Blast_Score=315, Evalue=2e-85,
Organism=Homo sapiens, GI94721241, Length=810, Percent_Identity=30.2469135802469, Blast_Score=315, Evalue=2e-85,
Organism=Homo sapiens, GI268370297, Length=877, Percent_Identity=25.6556442417332, Blast_Score=204, Evalue=4e-52,
Organism=Homo sapiens, GI268370293, Length=877, Percent_Identity=25.6556442417332, Blast_Score=204, Evalue=4e-52,
Organism=Homo sapiens, GI268370295, Length=868, Percent_Identity=25.5760368663594, Blast_Score=202, Evalue=2e-51,
Organism=Homo sapiens, GI5454158, Length=916, Percent_Identity=24.1266375545852, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI7661872, Length=184, Percent_Identity=25.5434782608696, Blast_Score=69, Evalue=3e-11,
Organism=Escherichia coli, GI2367096, Length=966, Percent_Identity=43.3747412008282, Blast_Score=768, Evalue=0.0,
Organism=Escherichia coli, GI1790708, Length=838, Percent_Identity=23.3890214797136, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI1786861, Length=429, Percent_Identity=28.9044289044289, Blast_Score=110, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71980946, Length=980, Percent_Identity=33.0612244897959, Blast_Score=498, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI17541896, Length=760, Percent_Identity=28.0263157894737, Blast_Score=284, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17510661, Length=881, Percent_Identity=25.0851305334847, Blast_Score=228, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI72001587, Length=809, Percent_Identity=23.3621755253399, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71997517, Length=189, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997510, Length=189, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325217, Length=1018, Percent_Identity=37.721021611002, Blast_Score=622, Evalue=1e-179,
Organism=Saccharomyces cerevisiae, GI6319395, Length=817, Percent_Identity=28.1517747858017, Blast_Score=297, Evalue=5e-81,
Organism=Saccharomyces cerevisiae, GI6321531, Length=893, Percent_Identity=24.7480403135498, Blast_Score=210, Evalue=7e-55,
Organism=Saccharomyces cerevisiae, GI6323414, Length=615, Percent_Identity=22.9268292682927, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281366294, Length=975, Percent_Identity=35.3846153846154, Blast_Score=556, Evalue=1e-158,
Organism=Drosophila melanogaster, GI28574730, Length=816, Percent_Identity=29.1666666666667, Blast_Score=306, Evalue=6e-83,
Organism=Drosophila melanogaster, GI24668547, Length=816, Percent_Identity=29.1666666666667, Blast_Score=306, Evalue=6e-83,
Organism=Drosophila melanogaster, GI24668543, Length=816, Percent_Identity=29.1666666666667, Blast_Score=306, Evalue=6e-83,
Organism=Drosophila melanogaster, GI17864482, Length=878, Percent_Identity=24.6013667425968, Blast_Score=198, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24653289, Length=878, Percent_Identity=24.6013667425968, Blast_Score=198, Evalue=2e-50,
Organism=Drosophila melanogaster, GI21355675, Length=826, Percent_Identity=21.7917675544794, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21355409, Length=145, Percent_Identity=26.8965517241379, Blast_Score=66, Evalue=1e-10,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_NOSS1 (Q8YXY3)

Other databases:

- EMBL:   BA000019
- PIR:   AF1940
- RefSeq:   NP_485116.1
- ProteinModelPortal:   Q8YXY3
- SMR:   Q8YXY3
- STRING:   Q8YXY3
- GeneID:   1104667
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr1073
- NMPDR:   fig|103690.1.peg.1383
- eggNOG:   COG0060
- HOGENOM:   HBG577712
- OMA:   KQVLTHG
- PhylomeDB:   Q8YXY3
- ProtClustDB:   PRK05743
- BioCyc:   NSP103690:ALR1073-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_02002
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- InterPro:   IPR010663
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; PF06827 zf-FPG_IleRS; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 108395; Mature: 108264

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 573-573 BINDING 617-617

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETGSYKDTVNLPKTNFDMRANAIKREPEIQKFWEENKIFESLSQNNPGELFILHDGPP
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
YANGSLHIGHALNKILKDIINRYQLLQGRKVRYVPGWDCHGLPIELKVLQNLKSAERQNL
CCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
TPLQLRQKAKEFALATVDNQRQNFKRYGVWGDWDNPYLTLKPEYEAAQIGVFGQMVLKGY
CHHHHHHHHHHHHHHEECCHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
IYRGLKPVHWSPSSKTALAEAELEYPEGHTSRSIYAAFPVTSFAEAAKPLLGEYLPDLGV
HHHCCCCEECCCCCCCEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCE
AIWTTTPWTIPGNLAVAVNGDLNYSLVEVSRIGAETQSNFKYLIVAADLVERLAATISAQ
EEEECCCEECCCCEEEEEECCCCEEEEEHHHHCCCCCCCCEEEEEHHHHHHHHHHHHEEE
LTVKATFKGKELEHTTYRHPLFDRESPVVVGGDYITTESGTGLVHTAPGHGQEDYVVGLR
EEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCEEEECCCCEEEECCCCCCCCCEEEEEE
YGLPILAPVDDNGDFTQEAGQFAGLNVLGEGNQAVIDALTAAGSLLKEEAYAHKYPYDWR
CCCEEEEEECCCCCHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TKKPTIFRATEQWFASVEGFRDEALKAIAAVKWIPAQGENRITPMVAERSDWCISRQRSW
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEECCCCHHHHCCCCC
GVPIPVFYDEETGEPLLNEETINYVQAIIAEKGSDAWWELSVAELLPESYRNNGRSYRRG
CCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHCHHHHHCCCCCCCCC
TDTMDVWFDSGSSWASVVKQRPELRYPADMYLEGSDQHRGWFQSSLLTSVSVNGIAPYKT
CCCEEEEECCCCHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCHHHH
VLTHGFVLDEQGRKMSKSEGNVVDPAIIINGGKDQKKEPPYGADVMRLWASSVDYTGDVR
HHHCCCEECCCCCCCCCCCCCEECCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCEE
LGGNIIKQLNDVRGKIRNTARFLLGSLYDFDPEKNAVQFEEMPQLDKYMLHRIREVFEEV
ECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHH
TEAFESFQFFRFFQTVQNFCVVDLSNFYLDVAKDRLYISAPDAFRRRSCQTVIHIALENL
HHHHHHHHHHHHHHHHHHHEEEEHHHHHHEEECCEEEEECCHHHHHHHHHHHHHHHHHHH
ARAIAPVLCHTAEDIWQYLPYKTPYKSVFEAGWVQVEEKWHNPELAEFWQQLRQLRTDVN
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCEEEEHHCCCCHHHHHHHHHHHHHHHHH
KVLEQARVEKMIGSSLEAKALIYVKDANSRKAIATLNPEVGNGVDELRYLFLTSQVELLD
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHH
SADKLQDGKYTSQSDSWGIGVVNAEGQKCDRCWNYSTHVGESAEHPLLCERCVPALAGEF
CHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TETGSYKDTVNLPKTNFDMRANAIKREPEIQKFWEENKIFESLSQNNPGELFILHDGPP
CCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
YANGSLHIGHALNKILKDIINRYQLLQGRKVRYVPGWDCHGLPIELKVLQNLKSAERQNL
CCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
TPLQLRQKAKEFALATVDNQRQNFKRYGVWGDWDNPYLTLKPEYEAAQIGVFGQMVLKGY
CHHHHHHHHHHHHHHEECCHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
IYRGLKPVHWSPSSKTALAEAELEYPEGHTSRSIYAAFPVTSFAEAAKPLLGEYLPDLGV
HHHCCCCEECCCCCCCEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCE
AIWTTTPWTIPGNLAVAVNGDLNYSLVEVSRIGAETQSNFKYLIVAADLVERLAATISAQ
EEEECCCEECCCCEEEEEECCCCEEEEEHHHHCCCCCCCCEEEEEHHHHHHHHHHHHEEE
LTVKATFKGKELEHTTYRHPLFDRESPVVVGGDYITTESGTGLVHTAPGHGQEDYVVGLR
EEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCEEEECCCCEEEECCCCCCCCCEEEEEE
YGLPILAPVDDNGDFTQEAGQFAGLNVLGEGNQAVIDALTAAGSLLKEEAYAHKYPYDWR
CCCEEEEEECCCCCHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TKKPTIFRATEQWFASVEGFRDEALKAIAAVKWIPAQGENRITPMVAERSDWCISRQRSW
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEECCCCHHHHCCCCC
GVPIPVFYDEETGEPLLNEETINYVQAIIAEKGSDAWWELSVAELLPESYRNNGRSYRRG
CCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHCHHHHHCCCCCCCCC
TDTMDVWFDSGSSWASVVKQRPELRYPADMYLEGSDQHRGWFQSSLLTSVSVNGIAPYKT
CCCEEEEECCCCHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCHHHH
VLTHGFVLDEQGRKMSKSEGNVVDPAIIINGGKDQKKEPPYGADVMRLWASSVDYTGDVR
HHHCCCEECCCCCCCCCCCCCEECCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCEE
LGGNIIKQLNDVRGKIRNTARFLLGSLYDFDPEKNAVQFEEMPQLDKYMLHRIREVFEEV
ECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHH
TEAFESFQFFRFFQTVQNFCVVDLSNFYLDVAKDRLYISAPDAFRRRSCQTVIHIALENL
HHHHHHHHHHHHHHHHHHHEEEEHHHHHHEEECCEEEEECCHHHHHHHHHHHHHHHHHHH
ARAIAPVLCHTAEDIWQYLPYKTPYKSVFEAGWVQVEEKWHNPELAEFWQQLRQLRTDVN
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCEEEEHHCCCCHHHHHHHHHHHHHHHHH
KVLEQARVEKMIGSSLEAKALIYVKDANSRKAIATLNPEVGNGVDELRYLFLTSQVELLD
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHH
SADKLQDGKYTSQSDSWGIGVVNAEGQKCDRCWNYSTHVGESAEHPLLCERCVPALAGEF
CHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840