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The map label for this gene is fur [C]

Identifier: 17228452

GI number: 17228452

Start: 1111860

End: 1112309

Strand: Direct

Name: fur [C]

Synonym: alr0957

Alternate gene names: 17228452

Gene position: 1111860-1112309 (Clockwise)

Preceding gene: 17228448

Following gene: 17228455

Centisome position: 17.34

GC content: 40.67

Gene sequence:

>450_bases
ATGCAGCAACAGGCAATATCGACAAAACCAATTCGTTCTCTAGAAGATGCTCTTGAGCGTTGTCAGCTGTTAGGTATGCG
CGTCAGTCGCCAGCGCCGCTTTATTTTAGAACTGCTGTGGCAAGCAAATGAGCATCTTTCTGCTAGAGAAATTTATGATC
GCCTCAACCAACAAGGCAAAGACATTGGTCATACATCTGTATATCAAAACTTAGAAGCATTATCAACTCAAGGCATTATT
GAGAGTATCGAACGTTGTGATGGGCGTTTATACGGCAACATTAGTGACTCTCACAGTCATGTTAACTGCTTAGACACTAA
CCAAATTTTGGATGTGCATATTCAACTTCCAGAGGCATTTATCCAAGAAGTTGAACAAAGAACAGGAGTGAAGATTACAG
ATTATAGTATCAACTTCTATGGATATCGGCATCCTCAAGATGAAGAGTAG

Upstream 100 bases:

>100_bases
ACAGTTAGAGGTAAGGCAGTGTTATTTAATATCCTCACATATATACAACAGCAATAACCATCAAACTGGGAAAGATCCCC
AATAGTAAATAGACATAAAT

Downstream 100 bases:

>100_bases
AAAGGCTGGGAGTAGGGGAAGAAGAAAACTGTACAGACGCGATTAATCGCGTCTCTGACAACTGACTAAAAATCCAGCAC
TACTCATAACTCACTTTTAC

Product: ferric uptake regulator

Products: NA

Alternate protein names: Ferric Uptake Regulator; Ferric Uptake Regulator Fur Family; Ferric Uptake Regulation Protein; FUR Family Transcriptional Regulator; Transcriptional Regulator Fur Family; Transcriptional Regulator Fur Family Protein; Fur Family Ferric Uptake Regulator; Fe2+/Zn2+ Uptake Regulation Proteins

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MQQQAISTKPIRSLEDALERCQLLGMRVSRQRRFILELLWQANEHLSAREIYDRLNQQGKDIGHTSVYQNLEALSTQGII
ESIERCDGRLYGNISDSHSHVNCLDTNQILDVHIQLPEAFIQEVEQRTGVKITDYSINFYGYRHPQDEE

Sequences:

>Translated_149_residues
MQQQAISTKPIRSLEDALERCQLLGMRVSRQRRFILELLWQANEHLSAREIYDRLNQQGKDIGHTSVYQNLEALSTQGII
ESIERCDGRLYGNISDSHSHVNCLDTNQILDVHIQLPEAFIQEVEQRTGVKITDYSINFYGYRHPQDEE
>Mature_149_residues
MQQQAISTKPIRSLEDALERCQLLGMRVSRQRRFILELLWQANEHLSAREIYDRLNQQGKDIGHTSVYQNLEALSTQGII
ESIERCDGRLYGNISDSHSHVNCLDTNQILDVHIQLPEAFIQEVEQRTGVKITDYSINFYGYRHPQDEE

Specific function: Acts As A Global Negative Controlling Element, Employing Fe(2+) As A Cofactor To Bind The Operator Of The Repressed Genes. Regulates The Expression Of Several Outer-Membrane Proteins Including The Iron Transport Operon. [C]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786899, Length=121, Percent_Identity=29.7520661157025, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 17329; Mature: 17329

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQQAISTKPIRSLEDALERCQLLGMRVSRQRRFILELLWQANEHLSAREIYDRLNQQGK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
DIGHTSVYQNLEALSTQGIIESIERCDGRLYGNISDSHSHVNCLDTNQILDVHIQLPEAF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCEEEEECCCCEEEEEEECCHHH
IQEVEQRTGVKITDYSINFYGYRHPQDEE
HHHHHHHCCCEEEEEEEEEEECCCCCCCC
>Mature Secondary Structure
MQQQAISTKPIRSLEDALERCQLLGMRVSRQRRFILELLWQANEHLSAREIYDRLNQQGK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
DIGHTSVYQNLEALSTQGIIESIERCDGRLYGNISDSHSHVNCLDTNQILDVHIQLPEAF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCEEEEECCCCEEEEEEECCHHH
IQEVEQRTGVKITDYSINFYGYRHPQDEE
HHHHHHHCCCEEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA