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The map label for this gene is hsdM [H]

Identifier: 170761898

GI number: 170761898

Start: 126341

End: 126904

Strand: Direct

Name: hsdM [H]

Synonym: UPA3_0103

Alternate gene names: 170761898

Gene position: 126341-126904 (Clockwise)

Preceding gene: 170762424

Following gene: 170762395

Centisome position: 16.81

GC content: 23.23

Gene sequence:

>564_bases
ATGGATAATAAAAAAGAAATTGAACGAAACAATTTACATGCAACAATTTGAAAAATTGCTGATGAGCTCCGTGGCGCAAT
TGATGGATGAGATTTTAAACAATATGTTTTAGGAATATTATTTTATCGATATATATCAGAAAACTTAACTAAATATATTA
ACGATAATGAGCATAAAATAGGTGATCATGATTTTAACTATGAAACATGTAATGATGATGATGTAGATGAAGAAATGAAA
ATAACCTTAATTAAAGAAAAAGGTTTTTATATTAAGCCGTCATTTTTGTTTGCTAATATTGTTAAAAATGCTGAAAAAAA
TGAAAATTTAAATGAAACTTTGGAAACTGTTTTTAACAATATTGAAGGATCATCCTCTGGTTATGATTCTGAAAAAAATT
TAAAAGGGTTATTTAATGATATTGATGTTAATAATAGTCGTTTAGGAAGTACTACACAAGAAAGAAATAAAAGACTAGCA
AGAATTTTAATTAGAATTATATATAAAAATATGGATTTATTAATTTTAAAACCATATATAAATAAAAAAGAGATTCCTAA
TTAA

Upstream 100 bases:

>100_bases
AAGGCAAATTTTCAATAACAAATGTGTGTGGAATATTAAAGGTGTTTGATAATTCTAATTAACAAACTTAAAAATATAAA
TTTATAAAGGGTTTATAAAT

Downstream 100 bases:

>100_bases
CTTAGTAATCTCTATCATTTAATTAAATACTTTTTAATTAATGTTGGTGACTGTGATGATGATGGTGTTCATGTTCGTGA
CCACCACAGCAATCATCTTT

Product: hypothetical protein

Products: NA

Alternate protein names: M.EcoR124II [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MDNKKEIERNNLHATIWKIADELRGAIDGWDFKQYVLGILFYRYISENLTKYINDNEHKIGDHDFNYETCNDDDVDEEMK
ITLIKEKGFYIKPSFLFANIVKNAEKNENLNETLETVFNNIEGSSSGYDSEKNLKGLFNDIDVNNSRLGSTTQERNKRLA
RILIRIIYKNMDLLILKPYINKKEIPN

Sequences:

>Translated_187_residues
MDNKKEIERNNLHATI*KIADELRGAIDG*DFKQYVLGILFYRYISENLTKYINDNEHKIGDHDFNYETCNDDDVDEEMK
ITLIKEKGFYIKPSFLFANIVKNAEKNENLNETLETVFNNIEGSSSGYDSEKNLKGLFNDIDVNNSRLGSTTQERNKRLA
RILIRIIYKNMDLLILKPYINKKEIPN
>Mature_187_residues
MDNKKEIERNNLHATI*KIADELRGAIDG*DFKQYVLGILFYRYISENLTKYINDNEHKIGDHDFNYETCNDDDVDEEMK
ITLIKEKGFYIKPSFLFANIVKNAEKNENLNETLETVFNNIEGSSSGYDSEKNLKGLFNDIDVNNSRLGSTTQERNKRLA
RILIRIIYKNMDLLILKPYINKKEIPN

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities. The EcoR124/3 I enzyme recognizes 5'-GAAN(7)RTCG-3' [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR004546 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 21556; Mature: 21556

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNKKEIERNNLHATIKIADELRGAIDGDFKQYVLGILFYRYISENLTKYINDNEHKIGD
CCCHHHHHCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
HDFNYETCNDDDVDEEMKITLIKEKGFYIKPSFLFANIVKNAEKNENLNETLETVFNNIE
CCCCCCCCCCCCCCCCEEEEEEECCCCEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
GSSSGYDSEKNLKGLFNDIDVNNSRLGSTTQERNKRLARILIRIIYKNMDLLILKPYINK
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
KEIPN
CCCCC
>Mature Secondary Structure
MDNKKEIERNNLHATIKIADELRGAIDGDFKQYVLGILFYRYISENLTKYINDNEHKIGD
CCCHHHHHCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
HDFNYETCNDDDVDEEMKITLIKEKGFYIKPSFLFANIVKNAEKNENLNETLETVFNNIE
CCCCCCCCCCCCCCCCEEEEEEECCCCEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
GSSSGYDSEKNLKGLFNDIDVNNSRLGSTTQERNKRLARILIRIIYKNMDLLILKPYINK
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
KEIPN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2784505 [H]