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The map label for this gene is fhuB [H]

Identifier: 170757371

GI number: 170757371

Start: 390764

End: 391792

Strand: Direct

Name: fhuB [H]

Synonym: CLD_0442

Alternate gene names: 170757371

Gene position: 390764-391792 (Clockwise)

Preceding gene: 170757495

Following gene: 170756719

Centisome position: 9.87

GC content: 36.83

Gene sequence:

>1029_bases
ATGCAAAAGACCTATAATAAAAAGCGACAATTAGGAGCTTTGAATTTTACAATTTATATGATTGTAGGAGTGGTTTTGCT
AGTAATTATATCAGCGGCGTCAATTTCTTTTGGCGCTGCTGATATGAATTTGACTACAGCTTGGGGAGCCATTTTTAATT
TTGACTCTTCTTTAACTGAACATCAGATTATTCAAACTCTAAGGCTTCCTCGTATAGCAGCTAATATAATTGTTGGGTCA
AGCCTTGCAGTATGTGGTGCTATAATGCAGGGAACTACAAGAAATCCTCTTGCTGATTCTGGACTTATGGGTATAAGTAG
CGGTGCTACTTTTGCTATGGCTTTTTGTATGGCATTTTTACCTGGTGGAAGTTACGGACAGATGATGTTTTTTGCCTGCA
TTGGTGCAGCCGTTACTACAGGTATGACTTATTTTATTGCATCTATTGGTAGAGGAAGCATGAAACCACAGAGACTTGTT
TTAGCAGGTATTTCTATATCAATGCTATTTGGTGCTTTTAGCCAATATCTTTCTATTAAATATAGACTTGGACATGCATT
AGCTTATTGGACTGCTGGAGGAACGGCAGGTGCTAAATGGAGTGAACTTGCTATAGTTTTCCCATTTTTTATTGTAGGTA
TTATTGTAGCCCTTGTTATATCCCCTTCAATTACGGTTTTAAATCTTGGGGATGATGCAGCTATAGGTCTTGGACTTAAT
ACTAAGAAGGTTAAAGGGATATCTACTGTAGTAGTTTTAATACTTACAGGGCTTTCTGTAATTGTTGTTGGACCTGTTGG
CTTTGTAGGATTAATAGTACCTCATATTGTACGCTACCTTGTAGGGGTAGATTATAGATACATTATTCCAGCTTCAGGAT
TATATGGAGCCTTGATTACTGTGGCAGCAGATTTAGTTGGAAGGCTTATTAATAAGCCCTATGAAACTCCAATTGGAATT
ATTTTTGCTTTAATAGGTGTTCCATATTTTCTTTATCTTACAAGGATGCAAAGGAGGGAATTTGAATGA

Upstream 100 bases:

>100_bases
ATTATTCTGATATTACAAGTCTTACTGAACAGCTTGACTATATGAGTAATGCAATAAATTCATTAGTTAAATAATTCTAA
TATAAGAAAGGAAAATAAAT

Downstream 100 bases:

>100_bases
AGAAAAAAGGTTACTCAGTTTCACGTGGTCTAACTATTATTTTGCTACTTACCATTATTTTGTTAGTTGTGGCAGTAATA
AGTGTGAACTCAGGTAAAAT

Product: iron compound ABC transporter, permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein B; Ferrichrome transport system permease protein fhuB; Iron(III)-hydroxamate import system permease protein fhuB [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MQKTYNKKRQLGALNFTIYMIVGVVLLVIISAASISFGAADMNLTTAWGAIFNFDSSLTEHQIIQTLRLPRIAANIIVGS
SLAVCGAIMQGTTRNPLADSGLMGISSGATFAMAFCMAFLPGGSYGQMMFFACIGAAVTTGMTYFIASIGRGSMKPQRLV
LAGISISMLFGAFSQYLSIKYRLGHALAYWTAGGTAGAKWSELAIVFPFFIVGIIVALVISPSITVLNLGDDAAIGLGLN
TKKVKGISTVVVLILTGLSVIVVGPVGFVGLIVPHIVRYLVGVDYRYIIPASGLYGALITVAADLVGRLINKPYETPIGI
IFALIGVPYFLYLTRMQRREFE

Sequences:

>Translated_342_residues
MQKTYNKKRQLGALNFTIYMIVGVVLLVIISAASISFGAADMNLTTAWGAIFNFDSSLTEHQIIQTLRLPRIAANIIVGS
SLAVCGAIMQGTTRNPLADSGLMGISSGATFAMAFCMAFLPGGSYGQMMFFACIGAAVTTGMTYFIASIGRGSMKPQRLV
LAGISISMLFGAFSQYLSIKYRLGHALAYWTAGGTAGAKWSELAIVFPFFIVGIIVALVISPSITVLNLGDDAAIGLGLN
TKKVKGISTVVVLILTGLSVIVVGPVGFVGLIVPHIVRYLVGVDYRYIIPASGLYGALITVAADLVGRLINKPYETPIGI
IFALIGVPYFLYLTRMQRREFE
>Mature_342_residues
MQKTYNKKRQLGALNFTIYMIVGVVLLVIISAASISFGAADMNLTTAWGAIFNFDSSLTEHQIIQTLRLPRIAANIIVGS
SLAVCGAIMQGTTRNPLADSGLMGISSGATFAMAFCMAFLPGGSYGQMMFFACIGAAVTTGMTYFIASIGRGSMKPQRLV
LAGISISMLFGAFSQYLSIKYRLGHALAYWTAGGTAGAKWSELAIVFPFFIVGIIVALVISPSITVLNLGDDAAIGLGLN
TKKVKGISTVVVLILTGLSVIVVGPVGFVGLIVPHIVRYLVGVDYRYIIPASGLYGALITVAADLVGRLINKPYETPIGI
IFALIGVPYFLYLTRMQRREFE

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=280, Percent_Identity=34.2857142857143, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786347, Length=330, Percent_Identity=33.030303030303, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786805, Length=290, Percent_Identity=33.7931034482759, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1790740, Length=323, Percent_Identity=28.7925696594427, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788004, Length=276, Percent_Identity=32.6086956521739, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1786804, Length=288, Percent_Identity=29.1666666666667, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36408; Mature: 36408

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKTYNKKRQLGALNFTIYMIVGVVLLVIISAASISFGAADMNLTTAWGAIFNFDSSLTE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHH
HQIIQTLRLPRIAANIIVGSSLAVCGAIMQGTTRNPLADSGLMGISSGATFAMAFCMAFL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
PGGSYGQMMFFACIGAAVTTGMTYFIASIGRGSMKPQRLVLAGISISMLFGAFSQYLSIK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
YRLGHALAYWTAGGTAGAKWSELAIVFPFFIVGIIVALVISPSITVLNLGDDAAIGLGLN
HHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCC
TKKVKGISTVVVLILTGLSVIVVGPVGFVGLIVPHIVRYLVGVDYRYIIPASGLYGALIT
HHHHHHHHHHHHHHHHCCHHEEECHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHH
VAADLVGRLINKPYETPIGIIFALIGVPYFLYLTRMQRREFE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKTYNKKRQLGALNFTIYMIVGVVLLVIISAASISFGAADMNLTTAWGAIFNFDSSLTE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHH
HQIIQTLRLPRIAANIIVGSSLAVCGAIMQGTTRNPLADSGLMGISSGATFAMAFCMAFL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
PGGSYGQMMFFACIGAAVTTGMTYFIASIGRGSMKPQRLVLAGISISMLFGAFSQYLSIK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
YRLGHALAYWTAGGTAGAKWSELAIVFPFFIVGIIVALVISPSITVLNLGDDAAIGLGLN
HHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCC
TKKVKGISTVVVLILTGLSVIVVGPVGFVGLIVPHIVRYLVGVDYRYIIPASGLYGALIT
HHHHHHHHHHHHHHHHCCHHEEECHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHH
VAADLVGRLINKPYETPIGIIFALIGVPYFLYLTRMQRREFE
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377; 8388528 [H]