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The map label for this gene is fhuG [H]

Identifier: 170756719

GI number: 170756719

Start: 391789

End: 392802

Strand: Direct

Name: fhuG [H]

Synonym: CLD_0441

Alternate gene names: 170756719

Gene position: 391789-392802 (Clockwise)

Preceding gene: 170757371

Following gene: 170755942

Centisome position: 9.9

GC content: 34.52

Gene sequence:

>1014_bases
ATGAAGAAAAAAGGTTACTCAGTTTCACGTGGTCTAACTATTATTTTGCTACTTACCATTATTTTGTTAGTTGTGGCAGT
AATAAGTGTGAACTCAGGTAAAATGAATCTCTCTCCTTCGGAGGTTTTTAATGTTCTTATTGGAAGAGGTACAGATAAAC
AAAATCTTATAGTATATAATTTTCGTCTTCCTCGTATTGTATTAACTATGCTTGTAGGCATTGGTATGGGAACAGCTGGT
TGTGTAATGCAGAGTTTACTTCGCAATGATATGGCTAGTCCTGGAACTTTGGGAATAAGTTCTGGGTCAGGGTTATTTGT
ACTATTGTTCATAGTTATTTTTAAGGTAGACAGTGTATCTTCAGCTATTGCTCTACCACTTCTGGCGTTTGTAGGTGGAA
TGACAGCAGCTGTATTGATATTTTTACTTTCCTATAGAAGAGGAAAAACTATATCACCTACAGGATTAATTTTGACAGGG
GTAGCCGTTGGAAGTGGATATAGTGCTGTTACTATGATGCTTACTTTAAAGCTAGATGAAAAACAGATGGATTTTGTTCA
AAGATGGAGTGCAGGAAGTCTTTGGGGAGACAATTGGACATATATTTCTATTCTTGCACCTTGGGTGTTGATTCTATTTT
TATATGTATTTTATAAATCTAGTATTTTAAATACCTTAAATCTTGGGAATCAAACTGCAACAGGATTAGGAGTAGCAGTA
AAGCGTGAATTTATAGGGTTAACTGTAGCAGCTGTTGCTCTATCATCAGGTAGTGTAGCTTTAGGTGGAAACTTCTTTTT
TGTGGGAATGATTTCTCCACATATGGCAAGAAAGTTTGTAGGGTCAAATCATAAACTATTAATTCCTACAGCATCTTTAG
TAGGCTCAATAATTATTCTATTATCAGACACTATTACTAGAACTATAAGTTTTGGAAGTGATATTCCTACAGGAATTGTT
ATTACTGTATTAAGTACGCCCTACTTCTTATACCTATTAGTAAAGTCAAATTAA

Upstream 100 bases:

>100_bases
TTATTAATAAGCCCTATGAAACTCCAATTGGAATTATTTTTGCTTTAATAGGTGTTCCATATTTTCTTTATCTTACAAGG
ATGCAAAGGAGGGAATTTGA

Downstream 100 bases:

>100_bases
GGAGGTTTGTATGAAAAGTATTGAAACTAAAAATTTAGATATAGCTTATGAGGATACTCTCATTGTAAAAGAATTAAATA
TGCAGATACCAAAGGGTAAG

Product: iron compound ABC transporter, permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKKKGYSVSRGLTIILLLTIILLVVAVISVNSGKMNLSPSEVFNVLIGRGTDKQNLIVYNFRLPRIVLTMLVGIGMGTAG
CVMQSLLRNDMASPGTLGISSGSGLFVLLFIVIFKVDSVSSAIALPLLAFVGGMTAAVLIFLLSYRRGKTISPTGLILTG
VAVGSGYSAVTMMLTLKLDEKQMDFVQRWSAGSLWGDNWTYISILAPWVLILFLYVFYKSSILNTLNLGNQTATGLGVAV
KREFIGLTVAAVALSSGSVALGGNFFFVGMISPHMARKFVGSNHKLLIPTASLVGSIIILLSDTITRTISFGSDIPTGIV
ITVLSTPYFLYLLVKSN

Sequences:

>Translated_337_residues
MKKKGYSVSRGLTIILLLTIILLVVAVISVNSGKMNLSPSEVFNVLIGRGTDKQNLIVYNFRLPRIVLTMLVGIGMGTAG
CVMQSLLRNDMASPGTLGISSGSGLFVLLFIVIFKVDSVSSAIALPLLAFVGGMTAAVLIFLLSYRRGKTISPTGLILTG
VAVGSGYSAVTMMLTLKLDEKQMDFVQRWSAGSLWGDNWTYISILAPWVLILFLYVFYKSSILNTLNLGNQTATGLGVAV
KREFIGLTVAAVALSSGSVALGGNFFFVGMISPHMARKFVGSNHKLLIPTASLVGSIIILLSDTITRTISFGSDIPTGIV
ITVLSTPYFLYLLVKSN
>Mature_337_residues
MKKKGYSVSRGLTIILLLTIILLVVAVISVNSGKMNLSPSEVFNVLIGRGTDKQNLIVYNFRLPRIVLTMLVGIGMGTAG
CVMQSLLRNDMASPGTLGISSGSGLFVLLFIVIFKVDSVSSAIALPLLAFVGGMTAAVLIFLLSYRRGKTISPTGLILTG
VAVGSGYSAVTMMLTLKLDEKQMDFVQRWSAGSLWGDNWTYISILAPWVLILFLYVFYKSSILNTLNLGNQTATGLGVAV
KREFIGLTVAAVALSSGSVALGGNFFFVGMISPHMARKFVGSNHKLLIPTASLVGSIIILLSDTITRTISFGSDIPTGIV
ITVLSTPYFLYLLVKSN

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=287, Percent_Identity=33.1010452961672, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786804, Length=278, Percent_Identity=33.8129496402878, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786805, Length=306, Percent_Identity=31.6993464052288, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788004, Length=314, Percent_Identity=28.9808917197452, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790741, Length=297, Percent_Identity=29.6296296296296, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786347, Length=279, Percent_Identity=31.8996415770609, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35974; Mature: 35974

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKGYSVSRGLTIILLLTIILLVVAVISVNSGKMNLSPSEVFNVLIGRGTDKQNLIVYN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEE
FRLPRIVLTMLVGIGMGTAGCVMQSLLRNDMASPGTLGISSGSGLFVLLFIVIFKVDSVS
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHCCHH
SAIALPLLAFVGGMTAAVLIFLLSYRRGKTISPTGLILTGVAVGSGYSAVTMMLTLKLDE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCHHEEEEEEEEEECH
KQMDFVQRWSAGSLWGDNWTYISILAPWVLILFLYVFYKSSILNTLNLGNQTATGLGVAV
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KREFIGLTVAAVALSSGSVALGGNFFFVGMISPHMARKFVGSNHKLLIPTASLVGSIIIL
HHHHHHHHHHHHHHCCCCEEECCCEEEEEECCHHHHHHHHCCCCEEEEECHHHHHHHHHH
LSDTITRTISFGSDIPTGIVITVLSTPYFLYLLVKSN
HHHHHHHHHHCCCCCCCHHEEHHHCCCEEEEEEEECC
>Mature Secondary Structure
MKKKGYSVSRGLTIILLLTIILLVVAVISVNSGKMNLSPSEVFNVLIGRGTDKQNLIVYN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEE
FRLPRIVLTMLVGIGMGTAGCVMQSLLRNDMASPGTLGISSGSGLFVLLFIVIFKVDSVS
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHCCHH
SAIALPLLAFVGGMTAAVLIFLLSYRRGKTISPTGLILTGVAVGSGYSAVTMMLTLKLDE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCHHEEEEEEEEEECH
KQMDFVQRWSAGSLWGDNWTYISILAPWVLILFLYVFYKSSILNTLNLGNQTATGLGVAV
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KREFIGLTVAAVALSSGSVALGGNFFFVGMISPHMARKFVGSNHKLLIPTASLVGSIIIL
HHHHHHHHHHHHHHCCCCEEECCCEEEEEECCHHHHHHHHCCCCEEEEECHHHHHHHHHH
LSDTITRTISFGSDIPTGIVITVLSTPYFLYLLVKSN
HHHHHHHHHHCCCCCCCHHEEHHHCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]