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The map label for this gene is mmgC [H]

Identifier: 170757106

GI number: 170757106

Start: 3555072

End: 3556205

Strand: Reverse

Name: mmgC [H]

Synonym: CLD_1235

Alternate gene names: 170757106

Gene position: 3556205-3555072 (Counterclockwise)

Preceding gene: 170757677

Following gene: 170754647

Centisome position: 89.84

GC content: 33.51

Gene sequence:

>1134_bases
ATGTTTTTCACAGAACAACATGAACTTATTAGAAAATTAGCAAGAGATTTTGCAGAGCAGGAAATAGAGCCTATTGCAGA
TGAAGTAGATAAAACTGCCGAGTTCCCTAAAGAAATTGTGAAAAAAATGGCCCAAAATGGTTTCTTTGGAATAAAAATGC
CTAAAGAATATGGTGGAGCTGGAGCAGATAATAGAGCCTATGTAACTATAATGGAAGAGATATCAAGAGCATCTGGTGTA
GCTGGTATATATTTATCATCACCAAATTCATTGCTTGGCACACCATTCTTACTAGTTGGTACAGATGAACAAAAGGAAAA
ATATTTAAAACCAATGATTAGAGGAGAAAAAACATTAGCTTTTGCTTTAACAGAACCAGGTGCAGGTTCAGACGCAGGAG
CGCTTGCAACAACTGCTAGAGAAGAAGGAGACTATTATATATTAAATGGAAGAAAAACTTTTATTACAGGAGCGCCAATA
TCTGATAATATCATAGTGTTTGCAAAAACAGATATGAGCAAAGGAACAAAAGGAATTACTACATTTATAGTAGACAGTAA
ACAAGAGGGAGTGTCTTTTGGTAAACCTGAAGACAAGATGGGAATGATTGGTTGCCCTACCAGTGATATTATTCTAGAAA
ATGTAAAGGTTCATAAATCTGATATACTTGGAGAAGTAAATAAAGGCTTTATAACAGCAATGAAGACTTTAAGTGTTGGT
CGTATAGGAGTTGCTTCTCAAGCTTTAGGAATAGCACAAGCTGCTGTAGATGAAGCTGTTAAATATGCAAAACAAAGAAA
GCAATTTAATAGACCTATAGCAAAATTCCAAGCTATTCAATTTAAATTGGCTAACATGGAAACAAAATTAAATGCGGCAA
AATTATTAGTGTATAATGCTGCTTATAAAATGGATTGTGGAGAAAAGGCAGATAAAGAAGCTTCTATGGCAAAATATTTT
GCTGCTGAATCTGCTATACAAATCGTAAATGACGCACTACAAATCCATGGTGGTTATGGATACATAAAAGATTATAAAAT
AGAAAGATTATATAGAGATGTTAGAGTAATTGCTATATATGAAGGAACTTCTGAAGTTCAACAAATGGTAATCGCATCAA
ATCTTTTAAAGTAA

Upstream 100 bases:

>100_bases
AAATAATACTTATTTTTCAAAAAAGTTATCTTTGGATGGACGAAGGGAAATCAATGTTTATATAAATTAACAAATTCATT
AATATATTAGGAGGGATATA

Downstream 100 bases:

>100_bases
GGAGTGGAGAAATTGAAGATAGTTGTATGTGTAAAACAAGTACCAGATACTAATGAAGTAAAGATCGATCCTGTAAAAGG
AACTCTTATCCGTGAAGGTG

Product: acyl-CoA dehydrogenase family protein

Products: 2-butenoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MFFTEQHELIRKLARDFAEQEIEPIADEVDKTAEFPKEIVKKMAQNGFFGIKMPKEYGGAGADNRAYVTIMEEISRASGV
AGIYLSSPNSLLGTPFLLVGTDEQKEKYLKPMIRGEKTLAFALTEPGAGSDAGALATTAREEGDYYILNGRKTFITGAPI
SDNIIVFAKTDMSKGTKGITTFIVDSKQEGVSFGKPEDKMGMIGCPTSDIILENVKVHKSDILGEVNKGFITAMKTLSVG
RIGVASQALGIAQAAVDEAVKYAKQRKQFNRPIAKFQAIQFKLANMETKLNAAKLLVYNAAYKMDCGEKADKEASMAKYF
AAESAIQIVNDALQIHGGYGYIKDYKIERLYRDVRVIAIYEGTSEVQQMVIASNLLK

Sequences:

>Translated_377_residues
MFFTEQHELIRKLARDFAEQEIEPIADEVDKTAEFPKEIVKKMAQNGFFGIKMPKEYGGAGADNRAYVTIMEEISRASGV
AGIYLSSPNSLLGTPFLLVGTDEQKEKYLKPMIRGEKTLAFALTEPGAGSDAGALATTAREEGDYYILNGRKTFITGAPI
SDNIIVFAKTDMSKGTKGITTFIVDSKQEGVSFGKPEDKMGMIGCPTSDIILENVKVHKSDILGEVNKGFITAMKTLSVG
RIGVASQALGIAQAAVDEAVKYAKQRKQFNRPIAKFQAIQFKLANMETKLNAAKLLVYNAAYKMDCGEKADKEASMAKYF
AAESAIQIVNDALQIHGGYGYIKDYKIERLYRDVRVIAIYEGTSEVQQMVIASNLLK
>Mature_377_residues
MFFTEQHELIRKLARDFAEQEIEPIADEVDKTAEFPKEIVKKMAQNGFFGIKMPKEYGGAGADNRAYVTIMEEISRASGV
AGIYLSSPNSLLGTPFLLVGTDEQKEKYLKPMIRGEKTLAFALTEPGAGSDAGALATTAREEGDYYILNGRKTFITGAPI
SDNIIVFAKTDMSKGTKGITTFIVDSKQEGVSFGKPEDKMGMIGCPTSDIILENVKVHKSDILGEVNKGFITAMKTLSVG
RIGVASQALGIAQAAVDEAVKYAKQRKQFNRPIAKFQAIQFKLANMETKLNAAKLLVYNAAYKMDCGEKADKEASMAKYF
AAESAIQIVNDALQIHGGYGYIKDYKIERLYRDVRVIAIYEGTSEVQQMVIASNLLK

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=48.5333333333333, Blast_Score=356, Evalue=2e-98,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=39.9463806970509, Blast_Score=298, Evalue=4e-81,
Organism=Homo sapiens, GI7656849, Length=379, Percent_Identity=39.8416886543536, Blast_Score=271, Evalue=5e-73,
Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=38.3378016085791, Blast_Score=267, Evalue=1e-71,
Organism=Homo sapiens, GI226958414, Length=356, Percent_Identity=38.4831460674157, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI4557231, Length=374, Percent_Identity=38.2352941176471, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI187960098, Length=374, Percent_Identity=38.2352941176471, Blast_Score=252, Evalue=3e-67,
Organism=Homo sapiens, GI21361497, Length=364, Percent_Identity=39.2857142857143, Blast_Score=243, Evalue=1e-64,
Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=32.7127659574468, Blast_Score=222, Evalue=6e-58,
Organism=Homo sapiens, GI76496475, Length=373, Percent_Identity=34.8525469168901, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI4557235, Length=373, Percent_Identity=34.8525469168901, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI4503943, Length=372, Percent_Identity=28.494623655914, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI7669494, Length=362, Percent_Identity=28.7292817679558, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI48976061, Length=396, Percent_Identity=27.020202020202, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI211971008, Length=396, Percent_Identity=27.020202020202, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI38505218, Length=388, Percent_Identity=27.0618556701031, Blast_Score=119, Evalue=6e-27,
Organism=Escherichia coli, GI87081958, Length=379, Percent_Identity=33.7730870712401, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1786223, Length=374, Percent_Identity=32.8877005347594, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI87081702, Length=364, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082384, Length=289, Percent_Identity=24.5674740484429, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17508101, Length=370, Percent_Identity=39.7297297297297, Blast_Score=289, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI17538396, Length=380, Percent_Identity=38.6842105263158, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17506239, Length=375, Percent_Identity=36.5333333333333, Blast_Score=261, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI17534899, Length=379, Percent_Identity=39.3139841688654, Blast_Score=257, Evalue=9e-69,
Organism=Caenorhabditis elegans, GI17533517, Length=372, Percent_Identity=38.4408602150538, Blast_Score=253, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17570075, Length=378, Percent_Identity=37.5661375661376, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=37.9947229551451, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI71990804, Length=294, Percent_Identity=42.5170068027211, Blast_Score=237, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI71985184, Length=350, Percent_Identity=34.8571428571429, Blast_Score=211, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI71982178, Length=280, Percent_Identity=35.7142857142857, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI32563615, Length=234, Percent_Identity=38.4615384615385, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17551932, Length=377, Percent_Identity=31.8302387267904, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=31.7333333333333, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17534353, Length=372, Percent_Identity=28.2258064516129, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17531909, Length=238, Percent_Identity=36.9747899159664, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71985192, Length=286, Percent_Identity=34.2657342657343, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17562446, Length=329, Percent_Identity=28.8753799392097, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17531913, Length=176, Percent_Identity=33.5227272727273, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI86563381, Length=266, Percent_Identity=27.0676691729323, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=266, Percent_Identity=27.0676691729323, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17540912, Length=371, Percent_Identity=23.4501347708895, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=45.3333333333333, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=42.1333333333333, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24666513, Length=376, Percent_Identity=36.7021276595745, Blast_Score=268, Evalue=3e-72,
Organism=Drosophila melanogaster, GI21355753, Length=380, Percent_Identity=37.8947368421053, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24660351, Length=377, Percent_Identity=37.6657824933687, Blast_Score=251, Evalue=5e-67,
Organism=Drosophila melanogaster, GI281363737, Length=379, Percent_Identity=34.5646437994723, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI19920834, Length=373, Percent_Identity=30.8310991957105, Blast_Score=164, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.2

Molecular weight: Translated: 41344; Mature: 41344

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFTEQHELIRKLARDFAEQEIEPIADEVDKTAEFPKEIVKKMAQNGFFGIKMPKEYGGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHCCC
GADNRAYVTIMEEISRASGVAGIYLSSPNSLLGTPFLLVGTDEQKEKYLKPMIRGEKTLA
CCCCCEEEHHHHHHHHHCCCEEEEEECCCCHHCCCEEEEECCHHHHHHHHHHHCCCCEEE
FALTEPGAGSDAGALATTAREEGDYYILNGRKTFITGAPISDNIIVFAKTDMSKGTKGIT
EEEECCCCCCCCCHHHHHHHCCCCEEEECCCEEEEECCCCCCCEEEEEECCCCCCCCCEE
TFIVDSKQEGVSFGKPEDKMGMIGCPTSDIILENVKVHKSDILGEVNKGFITAMKTLSVG
EEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHCCC
RIGVASQALGIAQAAVDEAVKYAKQRKQFNRPIAKFQAIQFKLANMETKLNAAKLLVYNA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCCHHHCCCEEEEEEEC
AYKMDCGEKADKEASMAKYFAAESAIQIVNDALQIHGGYGYIKDYKIERLYRDVRVIAIY
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEEEEEE
EGTSEVQQMVIASNLLK
CCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFFTEQHELIRKLARDFAEQEIEPIADEVDKTAEFPKEIVKKMAQNGFFGIKMPKEYGGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHCCC
GADNRAYVTIMEEISRASGVAGIYLSSPNSLLGTPFLLVGTDEQKEKYLKPMIRGEKTLA
CCCCCEEEHHHHHHHHHCCCEEEEEECCCCHHCCCEEEEECCHHHHHHHHHHHCCCCEEE
FALTEPGAGSDAGALATTAREEGDYYILNGRKTFITGAPISDNIIVFAKTDMSKGTKGIT
EEEECCCCCCCCCHHHHHHHCCCCEEEECCCEEEEECCCCCCCEEEEEECCCCCCCCCEE
TFIVDSKQEGVSFGKPEDKMGMIGCPTSDIILENVKVHKSDILGEVNKGFITAMKTLSVG
EEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHCCC
RIGVASQALGIAQAAVDEAVKYAKQRKQFNRPIAKFQAIQFKLANMETKLNAAKLLVYNA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCCHHHCCCEEEEEEEC
AYKMDCGEKADKEASMAKYFAAESAIQIVNDALQIHGGYGYIKDYKIERLYRDVRVIAIY
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEEEEEE
EGTSEVQQMVIASNLLK
CCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: butanoyl-CoA; acceptor

Specific reaction: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]