Click here to switch to the map view.

The map label for this gene is ttdA [C]

Identifier: 170756587

GI number: 170756587

Start: 3754849

End: 3755691

Strand: Reverse

Name: ttdA [C]

Synonym: CLD_1063

Alternate gene names: 170756587

Gene position: 3755691-3754849 (Counterclockwise)

Preceding gene: 170754631

Following gene: 170755007

Centisome position: 94.88

GC content: 32.38

Gene sequence:

>843_bases
ATGAGGGAAATATCAGTAAATACTATAAAAAAAGTAGTGAAAAAATTATGCATAGAAGCTAATTATTATTTGCCTAAAGA
TGTAGATGACAAAATAGTACAATGTAGAGAAGTAGAAACTTGGAACATAGCTAGAGAGGTTTTACAAACTATAGAAGAAA
ATATACATATAGCTAGAAAAGAGAATATACCCTTATGTCAGGATACAGGTATGGCATGTATATTTATTGAAATGGGTCAA
GATGTTCATGTAATTGGAGGATCTCTAGAAGATGCTATTAATGAAGGTGTAGCAGAAGGATACAAGGAAGGATATTTAAG
AAAATCTATAGTTAGTGACCCTATAGAAAGAATAAACACAGAAGATAATACCCCAGCAGTAATATATTATAATATAGTTC
AAGGGAATAAAATTAAGATAACCGTAGCTCCAAAGGGGTTTGGATCAGAAAATATGAGTAAGATAGCTATGTTAAAGCCA
GCAGATGGATTAGAAGGTATAAAAAATTTTATTTTAGATGTGGTTAAAGAAGCAGGGCCTAATCCATGCCCACCTATAGT
TGTAGGAGTTGGCATAGGAGGGACTTTTGATAAATGTGCTTATTTGTCTAAAAAGGCACTTTTAAGATCAATAAATTTGG
GAAATAAAAATAAATTTTATAAAGATTTAGAGGAAGAATTACTAGAAAAAATTAATAGTTTAGGCATAGGGCCTCAAGGC
TTTGGTGGGAAAACTACAGCGTTGGCGGTTAATATAGAAACCTTCCCAACTCACATAGCAGGGTTACCAGTAGCAGTAAA
TGTAAGTTGCCATGTTACTAGGCATAAAGAGGAAATAATATAA

Upstream 100 bases:

>100_bases
TTTTATAAAGATCGATGTAGATTGATGTAGAAAAAAATATGTAATTAAACTATAATATTCATAAGTATGTGTTTTAAAAT
ATTGTATTTTGGAGGATAAA

Downstream 100 bases:

>100_bases
AAATTATAGTTTATATTATTTATATATTCTATGTGTAAAATAAATAAATATAACCTCCTTTAATATATTCTAAAGGAGAT
ATAAAGAGCAGGTGATTTTA

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MREISVNTIKKVVKKLCIEANYYLPKDVDDKIVQCREVETWNIAREVLQTIEENIHIARKENIPLCQDTGMACIFIEMGQ
DVHVIGGSLEDAINEGVAEGYKEGYLRKSIVSDPIERINTEDNTPAVIYYNIVQGNKIKITVAPKGFGSENMSKIAMLKP
ADGLEGIKNFILDVVKEAGPNPCPPIVVGVGIGGTFDKCAYLSKKALLRSINLGNKNKFYKDLEEELLEKINSLGIGPQG
FGGKTTALAVNIETFPTHIAGLPVAVNVSCHVTRHKEEII

Sequences:

>Translated_280_residues
MREISVNTIKKVVKKLCIEANYYLPKDVDDKIVQCREVETWNIAREVLQTIEENIHIARKENIPLCQDTGMACIFIEMGQ
DVHVIGGSLEDAINEGVAEGYKEGYLRKSIVSDPIERINTEDNTPAVIYYNIVQGNKIKITVAPKGFGSENMSKIAMLKP
ADGLEGIKNFILDVVKEAGPNPCPPIVVGVGIGGTFDKCAYLSKKALLRSINLGNKNKFYKDLEEELLEKINSLGIGPQG
FGGKTTALAVNIETFPTHIAGLPVAVNVSCHVTRHKEEII
>Mature_280_residues
MREISVNTIKKVVKKLCIEANYYLPKDVDDKIVQCREVETWNIAREVLQTIEENIHIARKENIPLCQDTGMACIFIEMGQ
DVHVIGGSLEDAINEGVAEGYKEGYLRKSIVSDPIERINTEDNTPAVIYYNIVQGNKIKITVAPKGFGSENMSKIAMLKP
ADGLEGIKNFILDVVKEAGPNPCPPIVVGVGIGGTFDKCAYLSKKALLRSINLGNKNKFYKDLEEELLEKINSLGIGPQG
FGGKTTALAVNIETFPTHIAGLPVAVNVSCHVTRHKEEII

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=277, Percent_Identity=31.4079422382672, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1790564, Length=243, Percent_Identity=33.7448559670782, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787897, Length=245, Percent_Identity=33.469387755102, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30779; Mature: 30779

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREISVNTIKKVVKKLCIEANYYLPKDVDDKIVQCREVETWNIAREVLQTIEENIHIARK
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCEEEEEC
ENIPLCQDTGMACIFIEMGQDVHVIGGSLEDAINEGVAEGYKEGYLRKSIVSDPIERINT
CCCCCCCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EDNTPAVIYYNIVQGNKIKITVAPKGFGSENMSKIAMLKPADGLEGIKNFILDVVKEAGP
CCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCC
NPCPPIVVGVGIGGTFDKCAYLSKKALLRSINLGNKNKFYKDLEEELLEKINSLGIGPQG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
FGGKTTALAVNIETFPTHIAGLPVAVNVSCHVTRHKEEII
CCCCEEEEEEEEECCCHHHCCCCEEEEEEEEEECCHHHCC
>Mature Secondary Structure
MREISVNTIKKVVKKLCIEANYYLPKDVDDKIVQCREVETWNIAREVLQTIEENIHIARK
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCEEEEEC
ENIPLCQDTGMACIFIEMGQDVHVIGGSLEDAINEGVAEGYKEGYLRKSIVSDPIERINT
CCCCCCCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EDNTPAVIYYNIVQGNKIKITVAPKGFGSENMSKIAMLKPADGLEGIKNFILDVVKEAGP
CCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCC
NPCPPIVVGVGIGGTFDKCAYLSKKALLRSINLGNKNKFYKDLEEELLEKINSLGIGPQG
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
FGGKTTALAVNIETFPTHIAGLPVAVNVSCHVTRHKEEII
CCCCEEEEEEEEECCCHHHCCCCEEEEEEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]