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The map label for this gene is yxdK [H]

Identifier: 170754686

GI number: 170754686

Start: 399100

End: 400080

Strand: Direct

Name: yxdK [H]

Synonym: CLD_0434

Alternate gene names: 170754686

Gene position: 399100-400080 (Clockwise)

Preceding gene: 170755698

Following gene: 170756682

Centisome position: 10.08

GC content: 25.59

Gene sequence:

>981_bases
ATGAAGTTATTTATAAAAGACAATAAAGGATATATAGTTGTATATTCTATAAGTATTTTTATTACATTAGGATATTTAGC
CCTTTCAGGATTTGTACAAATTGGTGAGTGTTTATATATAGTATTATTTAATACATTTATTTTAGTATGTTTTTTATTTT
TTAGATATTATAAGAATAAAGACGTATATAAATTTTTAGATAAGGGACTAAATAATTTAGATGAATCTTTTTTAGATTTA
GGGAATTCAGTTCTAGGGGAAGGTATCTCTAATATTTTAAAGAAAGAGCATAATTTGTATGAGGCTGAAATTATAAAACA
CAATAAGGTTTATAATGATCATCTAACATTTATAAATCAATGGGTTCATCAGATGAAAACACCTCTATCAGTAATTCAAC
TACAAATGCAAGAATACGAGGGAGAAGAGCCTGTTGAAAGTATGAAAGTTGAGATAAGTAAATTAAATAGAGGATTAAAT
ATGGCCATATATTTTGCTAGACTTGATTCTTTTCAAAAAGATTTCATAGTAGAAAAATTTTCTTTATATAATTTAGTTAT
GAGTAAAGTTAATGAAGAAAAGCAGATATTTATTAAAAACAAGATATTACCAAAAGTTGAAATAGATGATTCTATAGAAG
TATATAGTGATGTTAAATGGATGAAATTTGTATTAGAACAGCTCATTGTTAATGGAGTAAAATATTCCAAAGATAAGGGA
AAAGAATTAATTATAAGAGCTTATGATGAGGAAAATACTATTAAACTAAGTGTAATTGATAATGGTGTAGGAATACCAAA
AAAAGATATTAAAAGAGTTTTTGATCCATTTTTTACAGGGGAAAATGGACGTAATTTTGGAGAATCTACTGGAATGGGAT
TACATATAGTTAAAAGGATTTGTGACAGTTTAGGGCATGATGTATTTATAGAGTCTAAGGTTTCAGAGGGAACAACTGTT
TCTATAATATTTAAAAAGTAG

Upstream 100 bases:

>100_bases
AATAAGAAAAAGACTTCATAAGTTAGGAATAGAAGATGGAATAGAAACTGTAAGAGGTGTGGGATATAGATTGAATAAAA
CTTGGTAGGGAGCATAAAAA

Downstream 100 bases:

>100_bases
GATATCATATTAAATATATAAATAGGATAGATAGTTTAAAACTATACTATACTATTTTTTTTATTAATTAATAAGTGTGA
CATACATGTCATACTTATGT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKLFIKDNKGYIVVYSISIFITLGYLALSGFVQIGECLYIVLFNTFILVCFLFFRYYKNKDVYKFLDKGLNNLDESFLDL
GNSVLGEGISNILKKEHNLYEAEIIKHNKVYNDHLTFINQWVHQMKTPLSVIQLQMQEYEGEEPVESMKVEISKLNRGLN
MAIYFARLDSFQKDFIVEKFSLYNLVMSKVNEEKQIFIKNKILPKVEIDDSIEVYSDVKWMKFVLEQLIVNGVKYSKDKG
KELIIRAYDEENTIKLSVIDNGVGIPKKDIKRVFDPFFTGENGRNFGESTGMGLHIVKRICDSLGHDVFIESKVSEGTTV
SIIFKK

Sequences:

>Translated_326_residues
MKLFIKDNKGYIVVYSISIFITLGYLALSGFVQIGECLYIVLFNTFILVCFLFFRYYKNKDVYKFLDKGLNNLDESFLDL
GNSVLGEGISNILKKEHNLYEAEIIKHNKVYNDHLTFINQWVHQMKTPLSVIQLQMQEYEGEEPVESMKVEISKLNRGLN
MAIYFARLDSFQKDFIVEKFSLYNLVMSKVNEEKQIFIKNKILPKVEIDDSIEVYSDVKWMKFVLEQLIVNGVKYSKDKG
KELIIRAYDEENTIKLSVIDNGVGIPKKDIKRVFDPFFTGENGRNFGESTGMGLHIVKRICDSLGHDVFIESKVSEGTTV
SIIFKK
>Mature_326_residues
MKLFIKDNKGYIVVYSISIFITLGYLALSGFVQIGECLYIVLFNTFILVCFLFFRYYKNKDVYKFLDKGLNNLDESFLDL
GNSVLGEGISNILKKEHNLYEAEIIKHNKVYNDHLTFINQWVHQMKTPLSVIQLQMQEYEGEEPVESMKVEISKLNRGLN
MAIYFARLDSFQKDFIVEKFSLYNLVMSKVNEEKQIFIKNKILPKVEIDDSIEVYSDVKWMKFVLEQLIVNGVKYSKDKG
KELIIRAYDEENTIKLSVIDNGVGIPKKDIKRVFDPFFTGENGRNFGESTGMGLHIVKRICDSLGHDVFIESKVSEGTTV
SIIFKK

Specific function: Probable member of the two-component regulatory system yxdK/yxdJ. May activate yxdJ in response to the antibacterial protein LL-37 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=213, Percent_Identity=24.4131455399061, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI145693157, Length=246, Percent_Identity=25.609756097561, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=24.7826086956522, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37742; Mature: 37742

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFIKDNKGYIVVYSISIFITLGYLALSGFVQIGECLYIVLFNTFILVCFLFFRYYKNK
CEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DVYKFLDKGLNNLDESFLDLGNSVLGEGISNILKKEHNLYEAEIIKHNKVYNDHLTFINQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHH
WVHQMKTPLSVIQLQMQEYEGEEPVESMKVEISKLNRGLNMAIYFARLDSFQKDFIVEKF
HHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHH
SLYNLVMSKVNEEKQIFIKNKILPKVEIDDSIEVYSDVKWMKFVLEQLIVNGVKYSKDKG
HHHHHHHHHCCCHHEEEEHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KELIIRAYDEENTIKLSVIDNGVGIPKKDIKRVFDPFFTGENGRNFGESTGMGLHIVKRI
CEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
CDSLGHDVFIESKVSEGTTVSIIFKK
HHHCCCCEEEECCCCCCCEEEEEEEC
>Mature Secondary Structure
MKLFIKDNKGYIVVYSISIFITLGYLALSGFVQIGECLYIVLFNTFILVCFLFFRYYKNK
CEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DVYKFLDKGLNNLDESFLDLGNSVLGEGISNILKKEHNLYEAEIIKHNKVYNDHLTFINQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHH
WVHQMKTPLSVIQLQMQEYEGEEPVESMKVEISKLNRGLNMAIYFARLDSFQKDFIVEKF
HHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHH
SLYNLVMSKVNEEKQIFIKNKILPKVEIDDSIEVYSDVKWMKFVLEQLIVNGVKYSKDKG
HHHHHHHHHCCCHHEEEEHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KELIIRAYDEENTIKLSVIDNGVGIPKKDIKRVFDPFFTGENGRNFGESTGMGLHIVKRI
CEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
CDSLGHDVFIESKVSEGTTVSIIFKK
HHHCCCCEEEECCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 8867804 [H]