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The map label for this gene is aroA

Identifier: 170751984

GI number: 170751984

Start: 5948426

End: 5949775

Strand: Direct

Name: aroA

Synonym: Mrad2831_5616

Alternate gene names: 170751984

Gene position: 5948426-5949775 (Clockwise)

Preceding gene: 170751982

Following gene: 170751985

Centisome position: 97.87

GC content: 74.67

Gene sequence:

>1350_bases
GTGTCGCACGATTCGAGTCCCCAGCCCCTCACCGCCGCGCCGGGCGCTCCGCTGCGCGGACGCCTGCGCCCGCCCGGCGA
CAAGTCGATCTCGCACCGGTCCATGATCCTCGGCCTGCTCAGCCAGGGCGAGACGCGGGTCGAAGGTCTGCTGGAGGGCG
ACGACGTCCTACGCACCGCCGCCGCCGCGAAGGCGCTCGGGGCGGGCGTCGAGCGCCTCGGTCCGGGCCGCTGGCGGGTC
CAGGGCGTCGGCATCGGCGGCCTCGGCGATCCGGCCGACGTGCTCGATTTCGGCAATGCCGGCACGGGTTCCCGGCTGAT
GATGGGCGTGGTCGGCGGACAGCCGGTGACCGCGACCTTCGACGGCGACGCCTCCCTCCGCTCGCGGCCGATGCGCCGCA
TCCTCGACCCCCTCACCCGGATGGGCACGCAGGTCCTGTCTGAGGCGGAGGGCGGCCGGGTTCCCCTGACCCTGCGGGGC
CCCAGGGAGGCGATCCCGATCACCTACGAGACCCCGGCGGCCTCGGCGCAGATCAAGTCGGCGGTGCTGCTCGCCGGGCT
CAACGCGCCCGGCGTCACCACCGTGATCGAGGCGGCCGCGACGCGGGACCACACCGAGCGGATGCTGCGCCTGTTCGGCG
CCGCGGTCAGCGTCGAGCCGCACGGTCCGGGCGGCCACGGCCGCAAGGTCGCGCTGACCGGTCAGCCGACCCTGCGCGGC
ACCGACGTCGTGGTGCCGGCCGACCCGTCCTCGGCGGCGTTCCCGCTGGTGGCGGCGCTGATCGTGCCCGGCTCCGACGT
GGTGATCGAGGGCGTGATGATGAACCCGCTGCGCATCGGGCTGATCACGACGCTCCTCGAGATGGGCGCGCAGATCGAGC
GCGTGGCCGAGCGGGAGGAGGGCGGCGAGACCGTGGCCGACCTGCGCGTGCGCGCGAGCCGCCTGAACGGCGTCGACGTG
CCGGCCGAGCGGGCGCCCGCGATGATCGACGAGTACCCGGTGCTGGCGGTGGCGGCGAGCTTCGCGGAGGGCCGGACCCG
GATGAGCGGCCTGCACGAGCTGCGGGTGAAGGAATCGGACCGCCTCGCCGCCGTGGCGGCCGGGCTGGCGGCCAACGGTG
TCCGCCACACGGTCGAGGGCGACGACCTCGTGGTCGAGGGCGACGGCGCCGCGGCGCCGGGCGGCGGGACGGTCGAGACC
CATCTCGATCACCGCATCGCCATGGCGTTCCTGGTGATGGGACTCGCGGCGCGGAACCCGGTCACGGTCGATGACGGCGC
GATGATCGCCACGAGCTTCCCGAGCTTCCTTCCGACCATGCAGGCCCTCGGCGGCCGGATCGGGGCGTGA

Upstream 100 bases:

>100_bases
TTAACCGCGCGGCGATCTCACCGTCCGATTGCAGCGCCGCGGCAGGCCCGCGCGACGCGCCGGATCCAGGCCCACGTCTC
AGAGCCCGAACGGACGTCCC

Downstream 100 bases:

>100_bases
CCGCCATGCCGCTCGTCATCGCGATCGACGGACCGGCCGCGTCCGGCAAGGGCACCCTCGCCAAGCGCCTGGCCGATCAT
TACGGCCTGCCGCATCTCGA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSHDSSPQPLTAAPGAPLRGRLRPPGDKSISHRSMILGLLSQGETRVEGLLEGDDVLRTAAAAKALGAGVERLGPGRWRV
QGVGIGGLGDPADVLDFGNAGTGSRLMMGVVGGQPVTATFDGDASLRSRPMRRILDPLTRMGTQVLSEAEGGRVPLTLRG
PREAIPITYETPAASAQIKSAVLLAGLNAPGVTTVIEAAATRDHTERMLRLFGAAVSVEPHGPGGHGRKVALTGQPTLRG
TDVVVPADPSSAAFPLVAALIVPGSDVVIEGVMMNPLRIGLITTLLEMGAQIERVAEREEGGETVADLRVRASRLNGVDV
PAERAPAMIDEYPVLAVAASFAEGRTRMSGLHELRVKESDRLAAVAAGLAANGVRHTVEGDDLVVEGDGAAAPGGGTVET
HLDHRIAMAFLVMGLAARNPVTVDDGAMIATSFPSFLPTMQALGGRIGA

Sequences:

>Translated_449_residues
MSHDSSPQPLTAAPGAPLRGRLRPPGDKSISHRSMILGLLSQGETRVEGLLEGDDVLRTAAAAKALGAGVERLGPGRWRV
QGVGIGGLGDPADVLDFGNAGTGSRLMMGVVGGQPVTATFDGDASLRSRPMRRILDPLTRMGTQVLSEAEGGRVPLTLRG
PREAIPITYETPAASAQIKSAVLLAGLNAPGVTTVIEAAATRDHTERMLRLFGAAVSVEPHGPGGHGRKVALTGQPTLRG
TDVVVPADPSSAAFPLVAALIVPGSDVVIEGVMMNPLRIGLITTLLEMGAQIERVAEREEGGETVADLRVRASRLNGVDV
PAERAPAMIDEYPVLAVAASFAEGRTRMSGLHELRVKESDRLAAVAAGLAANGVRHTVEGDDLVVEGDGAAAPGGGTVET
HLDHRIAMAFLVMGLAARNPVTVDDGAMIATSFPSFLPTMQALGGRIGA
>Mature_448_residues
SHDSSPQPLTAAPGAPLRGRLRPPGDKSISHRSMILGLLSQGETRVEGLLEGDDVLRTAAAAKALGAGVERLGPGRWRVQ
GVGIGGLGDPADVLDFGNAGTGSRLMMGVVGGQPVTATFDGDASLRSRPMRRILDPLTRMGTQVLSEAEGGRVPLTLRGP
REAIPITYETPAASAQIKSAVLLAGLNAPGVTTVIEAAATRDHTERMLRLFGAAVSVEPHGPGGHGRKVALTGQPTLRGT
DVVVPADPSSAAFPLVAALIVPGSDVVIEGVMMNPLRIGLITTLLEMGAQIERVAEREEGGETVADLRVRASRLNGVDVP
AERAPAMIDEYPVLAVAASFAEGRTRMSGLHELRVKESDRLAAVAAGLAANGVRHTVEGDDLVVEGDGAAAPGGGTVETH
LDHRIAMAFLVMGLAARNPVTVDDGAMIATSFPSFLPTMQALGGRIGA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=452, Percent_Identity=28.3185840707965, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320332, Length=480, Percent_Identity=26.4583333333333, Blast_Score=101, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_METRJ (B1M0N9)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001758244.1
- ProteinModelPortal:   B1M0N9
- SMR:   B1M0N9
- GeneID:   6141692
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_5616
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- ProtClustDB:   PRK02427
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 46286; Mature: 46154

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDSSPQPLTAAPGAPLRGRLRPPGDKSISHRSMILGLLSQGETRVEGLLEGDDVLRTA
CCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHH
AAAKALGAGVERLGPGRWRVQGVGIGGLGDPADVLDFGNAGTGSRLMMGVVGGQPVTATF
HHHHHHHCCHHHCCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCEEEEEEECCCCEEEEE
DGDASLRSRPMRRILDPLTRMGTQVLSEAEGGRVPLTLRGPREAIPITYETPAASAQIKS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCHHHHHH
AVLLAGLNAPGVTTVIEAAATRDHTERMLRLFGAAVSVEPHGPGGHGRKVALTGQPTLRG
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECCCCCCC
TDVVVPADPSSAAFPLVAALIVPGSDVVIEGVMMNPLRIGLITTLLEMGAQIERVAEREE
CEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHC
GGETVADLRVRASRLNGVDVPAERAPAMIDEYPVLAVAASFAEGRTRMSGLHELRVKESD
CCCHHHHHHHHHHHCCCCCCCHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
RLAAVAAGLAANGVRHTVEGDDLVVEGDGAAAPGGGTVETHLDHRIAMAFLVMGLAARNP
HHHHHHHHHHHCCCEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
VTVDDGAMIATSFPSFLPTMQALGGRIGA
EEECCCCEEECCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SHDSSPQPLTAAPGAPLRGRLRPPGDKSISHRSMILGLLSQGETRVEGLLEGDDVLRTA
CCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHH
AAAKALGAGVERLGPGRWRVQGVGIGGLGDPADVLDFGNAGTGSRLMMGVVGGQPVTATF
HHHHHHHCCHHHCCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCEEEEEEECCCCEEEEE
DGDASLRSRPMRRILDPLTRMGTQVLSEAEGGRVPLTLRGPREAIPITYETPAASAQIKS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCHHHHHH
AVLLAGLNAPGVTTVIEAAATRDHTERMLRLFGAAVSVEPHGPGGHGRKVALTGQPTLRG
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECCCCCCC
TDVVVPADPSSAAFPLVAALIVPGSDVVIEGVMMNPLRIGLITTLLEMGAQIERVAEREE
CEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHC
GGETVADLRVRASRLNGVDVPAERAPAMIDEYPVLAVAASFAEGRTRMSGLHELRVKESD
CCCHHHHHHHHHHHCCCCCCCHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
RLAAVAAGLAANGVRHTVEGDDLVVEGDGAAAPGGGTVETHLDHRIAMAFLVMGLAARNP
HHHHHHHHHHHCCCEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
VTVDDGAMIATSFPSFLPTMQALGGRIGA
EEECCCCEEECCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA