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The map label for this gene is ltaE [H]

Identifier: 170751905

GI number: 170751905

Start: 5854886

End: 5855932

Strand: Direct

Name: ltaE [H]

Synonym: Mrad2831_5537

Alternate gene names: 170751905

Gene position: 5854886-5855932 (Clockwise)

Preceding gene: 170751903

Following gene: 170751908

Centisome position: 96.33

GC content: 71.92

Gene sequence:

>1047_bases
ATGAGACACGACGACTCGCAGCAATTCGCCAGCGACAACTATTCCGGCATCTGCCCGGAGGCCTGGACGGCGATGGAGGC
GGCCAATCGCGGCCACGCCCCGGCCTACGGCGAGGACGCCTGGACTGCCCGGGCGGCCGACGCGTTCCGGGACCTGTTCG
AGACCCCGTGCGAGGTGTTCTTCGCCTTCAACGGCACGGCCGCCAACGCGCTGGCCCTGGCGGCGTTGTGCCAGTCCTAC
CACAGCGTGATCTGCGCCGACTCGGCCCATGTCGAGACCGACGAGTGCGGCGCGCCGGAATTCTTCTCGAACGGCTCGAA
GCTGCTGACCGTCCGGACGGAGGGCGGCAAGCTCACGCCGGAGGCGATCCGCGGGCTCGCCCAGAACCGCAGCGACATCC
ACTTCCCGCGGCCGCGCGTGGTGACGATCACGCAGCCCACCGAGACCGGGCAGGTCTACAGCCTCGCCGAGCTGCGGGCC
CTGTCGGCGACCTGCCGGGAGCTGGGCCTCGCCCTGCACATGGACGGGTCGCGCTTCGCCAACGCCTGCGCGAGTCTCGG
CTGCAGCCCGGCCGACATGACGTGGCGGTCGGGCATCGACGTGCTGTGCTTCGGCGGGACCAAGAACGGCATGCATGCCG
GCGAGGCGGTGGTGTTCTTCGACGCCGCGCTCGCCGAGGATTTCGGCTACCGCTGCAAGCAGGCCGGACAGCTGGCCTCG
AAGATGCGCTTCCTCGCGGCGCCCTGGGTCGGCATGCTGGAGAGCGGCGCGTGGCTCAGGAACGCGGCCCACGGCAACGC
CTGCGCCCGGCGCTTCGCCGAGGCGGTCGCCGGGCTGCCGGGCGTGCGGGCGCTGTTTCCCGTCGAGGCGAACGCGGTCT
TCCTGACGATGCCCGCGGCCACGATGGAGGGCCTGCGCGCCCGGGGCTGGCGATTCTACACCTTCATCGGCGGAGGCGCG
CGCTTCATGTTCGCCTGGGATGCCCGGCCCGAGCGGGTCGACGAGCTGGTCGGCGACCTGCGCGCGCTGGCGGCCGCCGC
GGCCTGA

Upstream 100 bases:

>100_bases
CGTGGAGCTCACGCCTTGACGGGGCTATTACACCAAGCGCGCACCAGTTCCAACCTGTCCGCGCGATCCATCTGCGCCTG
CGCCGTGCTAGGTTGCGCGG

Downstream 100 bases:

>100_bases
GCCGCTGGACACAGAGGTTCGGAGCCGCACCGGAGGTGTTTCGCGCGCCGGTGCCGGGTTTCCCTGAGCGGTGTGAGTAC
GCTGGCGCGACGTGCGCTCG

Product: threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MRHDDSQQFASDNYSGICPEAWTAMEAANRGHAPAYGEDAWTARAADAFRDLFETPCEVFFAFNGTAANALALAALCQSY
HSVICADSAHVETDECGAPEFFSNGSKLLTVRTEGGKLTPEAIRGLAQNRSDIHFPRPRVVTITQPTETGQVYSLAELRA
LSATCRELGLALHMDGSRFANACASLGCSPADMTWRSGIDVLCFGGTKNGMHAGEAVVFFDAALAEDFGYRCKQAGQLAS
KMRFLAAPWVGMLESGAWLRNAAHGNACARRFAEAVAGLPGVRALFPVEANAVFLTMPAATMEGLRARGWRFYTFIGGGA
RFMFAWDARPERVDELVGDLRALAAAAA

Sequences:

>Translated_348_residues
MRHDDSQQFASDNYSGICPEAWTAMEAANRGHAPAYGEDAWTARAADAFRDLFETPCEVFFAFNGTAANALALAALCQSY
HSVICADSAHVETDECGAPEFFSNGSKLLTVRTEGGKLTPEAIRGLAQNRSDIHFPRPRVVTITQPTETGQVYSLAELRA
LSATCRELGLALHMDGSRFANACASLGCSPADMTWRSGIDVLCFGGTKNGMHAGEAVVFFDAALAEDFGYRCKQAGQLAS
KMRFLAAPWVGMLESGAWLRNAAHGNACARRFAEAVAGLPGVRALFPVEANAVFLTMPAATMEGLRARGWRFYTFIGGGA
RFMFAWDARPERVDELVGDLRALAAAAA
>Mature_348_residues
MRHDDSQQFASDNYSGICPEAWTAMEAANRGHAPAYGEDAWTARAADAFRDLFETPCEVFFAFNGTAANALALAALCQSY
HSVICADSAHVETDECGAPEFFSNGSKLLTVRTEGGKLTPEAIRGLAQNRSDIHFPRPRVVTITQPTETGQVYSLAELRA
LSATCRELGLALHMDGSRFANACASLGCSPADMTWRSGIDVLCFGGTKNGMHAGEAVVFFDAALAEDFGYRCKQAGQLAS
KMRFLAAPWVGMLESGAWLRNAAHGNACARRFAEAVAGLPGVRALFPVEANAVFLTMPAATMEGLRARGWRFYTFIGGGA
RFMFAWDARPERVDELVGDLRALAAAAA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320789, Length=330, Percent_Identity=25.7575757575758, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 37355; Mature: 37355

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHDDSQQFASDNYSGICPEAWTAMEAANRGHAPAYGEDAWTARAADAFRDLFETPCEVF
CCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHEE
FAFNGTAANALALAALCQSYHSVICADSAHVETDECGAPEFFSNGSKLLTVRTEGGKLTP
EEECCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCH
EAIRGLAQNRSDIHFPRPRVVTITQPTETGQVYSLAELRALSATCRELGLALHMDGSRFA
HHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCHHHH
NACASLGCSPADMTWRSGIDVLCFGGTKNGMHAGEAVVFFDAALAEDFGYRCKQAGQLAS
HHHHHCCCCCCCCHHHCCCCEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
KMRFLAAPWVGMLESGAWLRNAAHGNACARRFAEAVAGLPGVRALFPVEANAVFLTMPAA
HHHHHHCCHHHHHHCCHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECHH
TMEGLRARGWRFYTFIGGGARFMFAWDARPERVDELVGDLRALAAAAA
HHHHHHHCCEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRHDDSQQFASDNYSGICPEAWTAMEAANRGHAPAYGEDAWTARAADAFRDLFETPCEVF
CCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHEE
FAFNGTAANALALAALCQSYHSVICADSAHVETDECGAPEFFSNGSKLLTVRTEGGKLTP
EEECCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCH
EAIRGLAQNRSDIHFPRPRVVTITQPTETGQVYSLAELRALSATCRELGLALHMDGSRFA
HHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCHHHH
NACASLGCSPADMTWRSGIDVLCFGGTKNGMHAGEAVVFFDAALAEDFGYRCKQAGQLAS
HHHHHCCCCCCCCHHHCCCCEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
KMRFLAAPWVGMLESGAWLRNAAHGNACARRFAEAVAGLPGVRALFPVEANAVFLTMPAA
HHHHHHCCHHHHHHCCHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECHH
TMEGLRARGWRFYTFIGGGARFMFAWDARPERVDELVGDLRALAAAAA
HHHHHHHCCEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]