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The map label for this gene is 170751794

Identifier: 170751794

GI number: 170751794

Start: 5727648

End: 5728499

Strand: Direct

Name: 170751794

Synonym: Mrad2831_5424

Alternate gene names: NA

Gene position: 5727648-5728499 (Clockwise)

Preceding gene: 170751793

Following gene: 170751795

Centisome position: 94.24

GC content: 74.06

Gene sequence:

>852_bases
GTGACCGCCACCGCCACGCCCGCCCAGGACCCGGAGAGCGCCGCCCCGGCGCTGCCCGCCGCCGGCTCCTCCTTCTACAC
GGCGATGCGCCTGCTGCCGAAGGAGCGGCGGGAGGCGATGTACGCCGTCTACGCCTTCTGCCGCGCCGTCGACGACGTCG
CCGACGACGGCGGCACCCGCGCCGTCCGGCAGGTCGAGCTCGACCGCTGGCGGGCCGACATCGACGCCCTCTACGCCGGC
CGGCCGGCCGCGCGCGTGCGCGACCTCGTGGAGCCCGTGCGCCGCTTCGGCCTGAAGCGCGAGGATTTCCAGGCGGTCAT
CGACGGCATGGCGATGGACGCCGTCGAGGACATCGTCGCCCCCGACGCCGAGACCCTCGACCTCTACTGCGACCGGGTCG
CGAGCGCGGTCGGCCGGCTGTCGGTGCGGATCTTCGGCATGCCGGAGGCGGACGGCATCCGGCTGGCGTGGCATCAGGGC
CGCGCGCTCCAGCTCACCAACATCCTGCGCGACATCGACGAGGATGCCGAGCGCGGCCGCCTCTACCTGCCCCGGGAGAA
GCTCCGGGCGATCGGCCTCACCGACCCGACGCCGGTCCAGGCGATCAGCCATCCCCGCATCGGCGAGGTCTGCGTCTCCC
TCGCCCGCGAGGCCGAGGACCATTATCAGGCGACCTGGGAGATCATCCGGCGCAGCCCCCGCAAGGCGACCAAGGCCGCC
CGGCTGATGGCCGCCGCCTATCACCTCTACCTCAAGGCGGTCCTCGCGCGCGGCTGGGCGATGCCCCGCGCCCGGGTGAA
GCCCGGCAAGCTCGCGCTGCTGGGCGTCGTCCTCCGCCACGGCCTGATCTGA

Upstream 100 bases:

>100_bases
CCGCCTTCGCGCTGACGGCGCTGGGCGGCATCGCCGCCACCCTGGCGCGCCGGCCCTTCCGCGGCCGGACCGTCCGGGCC
GCGGCTCAGGGAATCCGCTC

Downstream 100 bases:

>100_bases
TGGGCACCGTCCACGTCGTCGGCGCCGGCCTCGCCGGCCTCTCCGCGGCCGTCGCGCTCGCCGAAACCGGCGCCCGGGTC
GTCCTGCACGAGGCCGCCAA

Product: squalene synthase HpnD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTATATPAQDPESAAPALPAAGSSFYTAMRLLPKERREAMYAVYAFCRAVDDVADDGGTRAVRQVELDRWRADIDALYAG
RPAARVRDLVEPVRRFGLKREDFQAVIDGMAMDAVEDIVAPDAETLDLYCDRVASAVGRLSVRIFGMPEADGIRLAWHQG
RALQLTNILRDIDEDAERGRLYLPREKLRAIGLTDPTPVQAISHPRIGEVCVSLAREAEDHYQATWEIIRRSPRKATKAA
RLMAAAYHLYLKAVLARGWAMPRARVKPGKLALLGVVLRHGLI

Sequences:

>Translated_283_residues
MTATATPAQDPESAAPALPAAGSSFYTAMRLLPKERREAMYAVYAFCRAVDDVADDGGTRAVRQVELDRWRADIDALYAG
RPAARVRDLVEPVRRFGLKREDFQAVIDGMAMDAVEDIVAPDAETLDLYCDRVASAVGRLSVRIFGMPEADGIRLAWHQG
RALQLTNILRDIDEDAERGRLYLPREKLRAIGLTDPTPVQAISHPRIGEVCVSLAREAEDHYQATWEIIRRSPRKATKAA
RLMAAAYHLYLKAVLARGWAMPRARVKPGKLALLGVVLRHGLI
>Mature_282_residues
TATATPAQDPESAAPALPAAGSSFYTAMRLLPKERREAMYAVYAFCRAVDDVADDGGTRAVRQVELDRWRADIDALYAGR
PAARVRDLVEPVRRFGLKREDFQAVIDGMAMDAVEDIVAPDAETLDLYCDRVASAVGRLSVRIFGMPEADGIRLAWHQGR
ALQLTNILRDIDEDAERGRLYLPREKLRAIGLTDPTPVQAISHPRIGEVCVSLAREAEDHYQATWEIIRRSPRKATKAAR
LMAAAYHLYLKAVLARGWAMPRARVKPGKLALLGVVLRHGLI

Specific function: Catalyzes the reaction from prephytoene diphosphate to phytoene. Probably part of an operon y4aABCD involved in the synthesis of an isoprenoid compound [H]

COG id: COG1562

COG function: function code I; Phytoene/squalene synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phytoene/squalene synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002060
- InterPro:   IPR017828
- InterPro:   IPR019845
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00494 SQS_PSY [H]

EC number: =2.5.1.32 [H]

Molecular weight: Translated: 31351; Mature: 31220

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS01044 SQUALEN_PHYTOEN_SYN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATATPAQDPESAAPALPAAGSSFYTAMRLLPKERREAMYAVYAFCRAVDDVADDGGTR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AVRQVELDRWRADIDALYAGRPAARVRDLVEPVRRFGLKREDFQAVIDGMAMDAVEDIVA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
PDAETLDLYCDRVASAVGRLSVRIFGMPEADGIRLAWHQGRALQLTNILRDIDEDAERGR
CCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCC
LYLPREKLRAIGLTDPTPVQAISHPRIGEVCVSLAREAEDHYQATWEIIRRSPRKATKAA
EECCHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RLMAAAYHLYLKAVLARGWAMPRARVKPGKLALLGVVLRHGLI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TATATPAQDPESAAPALPAAGSSFYTAMRLLPKERREAMYAVYAFCRAVDDVADDGGTR
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AVRQVELDRWRADIDALYAGRPAARVRDLVEPVRRFGLKREDFQAVIDGMAMDAVEDIVA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
PDAETLDLYCDRVASAVGRLSVRIFGMPEADGIRLAWHQGRALQLTNILRDIDEDAERGR
CCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCC
LYLPREKLRAIGLTDPTPVQAISHPRIGEVCVSLAREAEDHYQATWEIIRRSPRKATKAA
EECCHHHHHHCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RLMAAAYHLYLKAVLARGWAMPRARVKPGKLALLGVVLRHGLI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]