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The map label for this gene is lpsI [H]

Identifier: 170751382

GI number: 170751382

Start: 5323404

End: 5324144

Strand: Reverse

Name: lpsI [H]

Synonym: Mrad2831_5001

Alternate gene names: 170751382

Gene position: 5324144-5323404 (Counterclockwise)

Preceding gene: 170751385

Following gene: 170751381

Centisome position: 87.6

GC content: 68.96

Gene sequence:

>741_bases
ATGAAGAAGGTCTACACGGATGCCGCCGCCGCCCTGGCCGGCCTCCTGCACGACGACATGATGGTGATGTGCGGCGGCTT
CGGCCTCTGCGGCATCCCCGACGAGCTGATCGAGGCGGTGCGCCTCTCGGGCGTCAAGGGCCTCACGGTCGTGTCGAACA
ATGCCGGCATCGACGGGGTCGGCCTCGGCAAGCTCCTGGATACCCGCCAGGTCGCCAAGATGATCTCGTCCTACGTGGGC
GAGAACAAGGAGTTCGCCCGCCAGTATCTCGGCGGCGAGCTGGAGATCGAGTTCAACCCGCAGGGCACGCTGGCGGAGCG
GATCCGCGCCGGCGGCGCGGGCATCCCGGCCTTCTTCACCAAGACCGGCGTCGGCACCAAGGTCGCCGAGGGCAAGGAAG
TCCGCGAGTTCGACGGCGAGCAGTACGTGATGGAGCGCGGCCTGTTCGCCGACCTCGCCCTGGTCCACGCCCACACCGGC
GACACCGAGGGGAACCTGCGCTACCGGATGACCGCCCGCAACTTCAACCCGATGATGGCCACCGCCGCCAAGATGACGGT
GGCGCAGGTCGAGCACCTCGTGAAGCCCGGCGAGATCGACCCGGACACGATCCACACGCCCGGCATCTTCGTGAAGCGGA
TCATCGACGTCGGGCAGCGCGACAAGCGCATCGAGCAGCGCACTACGCGCAAGCGCGGCGACAGCACCCCGGCCGCGGCG
GCCGGCGGCGGCACGCACTGA

Upstream 100 bases:

>100_bases
CACCACTGGATTTCGCGCGCGGAATCGGGGAGAGCAGGCGCGAGGACACGCGCTTCCCAAGGTTTCGGCCGGTCGGATCC
GGCGGGAAAAGGACGGTTCG

Downstream 100 bases:

>100_bases
TCGGACGGGAAGGGAGCGAGAACGATGGCCTGGACCCGCGAGCAGATGGCGGCGCGCGCCGCCAAGGAGCTGGAGGACGG
CTTCTACGTGAACCTCGGCA

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKKVYTDAAAALAGLLHDDMMVMCGGFGLCGIPDELIEAVRLSGVKGLTVVSNNAGIDGVGLGKLLDTRQVAKMISSYVG
ENKEFARQYLGGELEIEFNPQGTLAERIRAGGAGIPAFFTKTGVGTKVAEGKEVREFDGEQYVMERGLFADLALVHAHTG
DTEGNLRYRMTARNFNPMMATAAKMTVAQVEHLVKPGEIDPDTIHTPGIFVKRIIDVGQRDKRIEQRTTRKRGDSTPAAA
AGGGTH

Sequences:

>Translated_246_residues
MKKVYTDAAAALAGLLHDDMMVMCGGFGLCGIPDELIEAVRLSGVKGLTVVSNNAGIDGVGLGKLLDTRQVAKMISSYVG
ENKEFARQYLGGELEIEFNPQGTLAERIRAGGAGIPAFFTKTGVGTKVAEGKEVREFDGEQYVMERGLFADLALVHAHTG
DTEGNLRYRMTARNFNPMMATAAKMTVAQVEHLVKPGEIDPDTIHTPGIFVKRIIDVGQRDKRIEQRTTRKRGDSTPAAA
AGGGTH
>Mature_246_residues
MKKVYTDAAAALAGLLHDDMMVMCGGFGLCGIPDELIEAVRLSGVKGLTVVSNNAGIDGVGLGKLLDTRQVAKMISSYVG
ENKEFARQYLGGELEIEFNPQGTLAERIRAGGAGIPAFFTKTGVGTKVAEGKEVREFDGEQYVMERGLFADLALVHAHTG
DTEGNLRYRMTARNFNPMMATAAKMTVAQVEHLVKPGEIDPDTIHTPGIFVKRIIDVGQRDKRIEQRTTRKRGDSTPAAA
AGGGTH

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=259, Percent_Identity=50.5791505791506, Blast_Score=253, Evalue=1e-67,
Organism=Homo sapiens, GI11545841, Length=250, Percent_Identity=47.6, Blast_Score=212, Evalue=2e-55,
Organism=Escherichia coli, GI1788551, Length=210, Percent_Identity=46.1904761904762, Blast_Score=191, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17531517, Length=261, Percent_Identity=49.0421455938697, Blast_Score=252, Evalue=1e-67,
Organism=Drosophila melanogaster, GI21358325, Length=242, Percent_Identity=50, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI24655794, Length=249, Percent_Identity=49.3975903614458, Blast_Score=237, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 26393; Mature: 26393

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVYTDAAAALAGLLHDDMMVMCGGFGLCGIPDELIEAVRLSGVKGLTVVSNNAGIDGV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCC
GLGKLLDTRQVAKMISSYVGENKEFARQYLGGELEIEFNPQGTLAERIRAGGAGIPAFFT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCCHHHH
KTGVGTKVAEGKEVREFDGEQYVMERGLFADLALVHAHTGDTEGNLRYRMTARNFNPMMA
CCCCCCCCCCCCHHHHHCCHHHHHHCCHHHHHHHHEEECCCCCCCEEEEEECCCCCHHHH
TAAKMTVAQVEHLVKPGEIDPDTIHTPGIFVKRIIDVGQRDKRIEQRTTRKRGDSTPAAA
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
AGGGTH
CCCCCC
>Mature Secondary Structure
MKKVYTDAAAALAGLLHDDMMVMCGGFGLCGIPDELIEAVRLSGVKGLTVVSNNAGIDGV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCC
GLGKLLDTRQVAKMISSYVGENKEFARQYLGGELEIEFNPQGTLAERIRAGGAGIPAFFT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCCHHHH
KTGVGTKVAEGKEVREFDGEQYVMERGLFADLALVHAHTGDTEGNLRYRMTARNFNPMMA
CCCCCCCCCCCCHHHHHCCHHHHHHCCHHHHHHHHEEECCCCCCCEEEEEECCCCCHHHH
TAAKMTVAQVEHLVKPGEIDPDTIHTPGIFVKRIIDVGQRDKRIEQRTTRKRGDSTPAAA
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
AGGGTH
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]