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The map label for this gene is ptrB [H]

Identifier: 170751335

GI number: 170751335

Start: 5276153

End: 5278288

Strand: Reverse

Name: ptrB [H]

Synonym: Mrad2831_4953

Alternate gene names: 170751335

Gene position: 5278288-5276153 (Counterclockwise)

Preceding gene: 170751339

Following gene: 170751333

Centisome position: 86.84

GC content: 72.24

Gene sequence:

>2136_bases
ATGACGGAGATCGGCCACGGCTTGCTCGCTCACAGGACCGGCGCGCCGGTGGCCGAGGCCCGGCCGCGGCGCTTCAGCGT
CCACGGGCAGGAGATCATTGACGACTACGCGTGGCTGAAGGCCGAGAACTGGCAGACGGTCCTGAAGGACCCGGCCGCGC
TGCCGGACGACATCGCCGCCTACCTGAAGGCCGAGAACGCCTTCGCCGAGGCGGCGCTCGCCGGGAGCGCGGAGCTGCGG
CGCCAGCTGGTCGCCGAGATGCGCGGGCGGATCCAGGAGGACGAGAGCGGCGTCCCCGAGCCCGACGGGCCCTTCGCGTA
CTACACGCGCCACCGCGAGGGCGGGCAGCACCCGCTGATCTGCCGGCGGCCGGCCACCGCCCCCGATGTGCCCGAGTCGG
GGCCGGACCCGGACGAGACGATCCTCATCGACGGCGACCGCGAGGGCGAGGGCCTGCCGTTCTTCGAGATCGCCGCCGCC
GTCCATTCCGACGACCACGCCCGCCTCGCCTGGAGCGTCGACACCAAGGGCTCGGAACTCTACACGATCCGGGTGCGCGA
CGTCGCCACCGGCCTCGACCTCGACGACCGGGTCGAGGCGACCTCCGGCGAGGCGGTCTGGGCCGCGGACGGCGCGAGCT
TCTGGTACGTGGCGGTCGACGCCAACCACCGGCCCGCCAAGGTGATGCGCCACCGCGTCGGCACGGGGCAGAGCGAGGAC
GAGACCGTCTACACGGAGGCCGACTCCGGCTACTTCGTCCACATCGGCAAGACGCAGTCCGGCGCCTTCCTCGACGTGAC
GGTGAGCGACCACGAGACCTCCGAGGTCCGGCTCCTCGACCGGCACGCGCAGGACGCCCGCCTGCGCCTCGTCGAGCCGC
GCACGCCGCTGCTGATCTACGGGGTCGAGCACCGCGGCGACCGCCTGTTCATCCGCACCAACGCGGACGGCGCCGAGGAC
TTCAAGATCGTCACCGCGCCGCTCGACGATCCGGGCCGCGCCCACTGGACCGACCTCGTGCCGCACCGGTCCGGGGTGAT
GATCCGCCACCTGCACCTGCTGGCCGGCCACCTGATCCGGCTGGAGATCGAGAACGCCAGGCCGCGGATCGTCGTGCGCG
ACCTCGCCGACGGTACCGAGCACACGGTCGCTTTCGCCGAGGAGGCCTACTCCCTCGGCCTGCGGGCCGGTCTCGCCTTC
GACACGGCCACGATCCGCTTCGTCTACTCGTCGATGACGACCCCGTCGGAGACCTGGGACTACGACTGCGCGGCCCGCAC
CCGGCTCCTGCGCAAGCGGCAGGTGGTGCCGAGCGGTCACGACCCGGCCGCCTACGTGACCCGGCGGCTCTTCGCCACCG
CGCCCGACGGCGAGCAGGTGCCGATCTCGCTGCTGCATCGCCGGGACCTCGCCCTCGACGGCGGCGCGCCGCTGCTGCTC
TACGGCTACGGCTCCTACGGCACGCTGATGCCGGCGGCGTTCCGCACGAACCTGCTGAGCCTCGTCGACCGCGGCTTCGT
CTACGCGATCGCCCATATCCGCGGCGGCACCGAGAAGGGCTGGCGCTGGTACCTCGACGGCAAGCGCGAGAAGAAGCCCA
ACACCTTCACGGACTTCATCGCCTGCGCGCGGGCGCTGATCGAGGCCCGCTACACGTCCGAGAAGCGCATCGTCGCCCAC
GGCGGGTCGGCCGGCGGGATGCTGATGGGGGCGGTGGCCAACCTCGCGCCGGAGCTGTTCGCCGGGATCGTCGCCGACGT
GCCCTTCGTCGACGTGCTCAACACCATGCTGGACGCGGAGCTGCCGCTGACGCCGCCGGAATGGCCCGAATGGGGCAACC
CGGGCGAGAGCGAGACCGCCTTCCGGACGATCCTGTCGTACTCGCCCTACGACAACGTCGCCGCCAAGGAATACCCGGCG
ATCCTGGCGCTCGGCGGGCTCACCGACCCGCGGGTGACCTACTGGGAGCCGGCCAAGTGGGTCGCGCGGCTGCGCGCCAC
CATGACGGGCGGCGGGCCGGTGCTCCTGCGGATCAACATGGAGGCCGGCCACGGCGGCGCCGCCGGCCGGTTCGACCGGC
TGGAGGAGGTGGCGCTGATCTACGCCTTCGCGCTCATGGCGGTGGGCAAGGCCTGA

Upstream 100 bases:

>100_bases
CGGCCCCGCCTCCGGACGCCTTGCATCCGCGCGCCCGGCGGGACACATCCGCTCACCCGGACGCGACACCCGCGCGCGAC
GGGACCCGACGGGAGAGACG

Downstream 100 bases:

>100_bases
GCGCCGCGCGGGCGCGGCGCCCGCGACGGGGTGCTGCGCCCGAGGCTCTCGGGGTGATCGCCCCCTTCCACGCCCTCATC
CCGCGGTGCCCGCCCCGGCG

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 711; Mature: 710

Protein sequence:

>711_residues
MTEIGHGLLAHRTGAPVAEARPRRFSVHGQEIIDDYAWLKAENWQTVLKDPAALPDDIAAYLKAENAFAEAALAGSAELR
RQLVAEMRGRIQEDESGVPEPDGPFAYYTRHREGGQHPLICRRPATAPDVPESGPDPDETILIDGDREGEGLPFFEIAAA
VHSDDHARLAWSVDTKGSELYTIRVRDVATGLDLDDRVEATSGEAVWAADGASFWYVAVDANHRPAKVMRHRVGTGQSED
ETVYTEADSGYFVHIGKTQSGAFLDVTVSDHETSEVRLLDRHAQDARLRLVEPRTPLLIYGVEHRGDRLFIRTNADGAED
FKIVTAPLDDPGRAHWTDLVPHRSGVMIRHLHLLAGHLIRLEIENARPRIVVRDLADGTEHTVAFAEEAYSLGLRAGLAF
DTATIRFVYSSMTTPSETWDYDCAARTRLLRKRQVVPSGHDPAAYVTRRLFATAPDGEQVPISLLHRRDLALDGGAPLLL
YGYGSYGTLMPAAFRTNLLSLVDRGFVYAIAHIRGGTEKGWRWYLDGKREKKPNTFTDFIACARALIEARYTSEKRIVAH
GGSAGGMLMGAVANLAPELFAGIVADVPFVDVLNTMLDAELPLTPPEWPEWGNPGESETAFRTILSYSPYDNVAAKEYPA
ILALGGLTDPRVTYWEPAKWVARLRATMTGGGPVLLRINMEAGHGGAAGRFDRLEEVALIYAFALMAVGKA

Sequences:

>Translated_711_residues
MTEIGHGLLAHRTGAPVAEARPRRFSVHGQEIIDDYAWLKAENWQTVLKDPAALPDDIAAYLKAENAFAEAALAGSAELR
RQLVAEMRGRIQEDESGVPEPDGPFAYYTRHREGGQHPLICRRPATAPDVPESGPDPDETILIDGDREGEGLPFFEIAAA
VHSDDHARLAWSVDTKGSELYTIRVRDVATGLDLDDRVEATSGEAVWAADGASFWYVAVDANHRPAKVMRHRVGTGQSED
ETVYTEADSGYFVHIGKTQSGAFLDVTVSDHETSEVRLLDRHAQDARLRLVEPRTPLLIYGVEHRGDRLFIRTNADGAED
FKIVTAPLDDPGRAHWTDLVPHRSGVMIRHLHLLAGHLIRLEIENARPRIVVRDLADGTEHTVAFAEEAYSLGLRAGLAF
DTATIRFVYSSMTTPSETWDYDCAARTRLLRKRQVVPSGHDPAAYVTRRLFATAPDGEQVPISLLHRRDLALDGGAPLLL
YGYGSYGTLMPAAFRTNLLSLVDRGFVYAIAHIRGGTEKGWRWYLDGKREKKPNTFTDFIACARALIEARYTSEKRIVAH
GGSAGGMLMGAVANLAPELFAGIVADVPFVDVLNTMLDAELPLTPPEWPEWGNPGESETAFRTILSYSPYDNVAAKEYPA
ILALGGLTDPRVTYWEPAKWVARLRATMTGGGPVLLRINMEAGHGGAAGRFDRLEEVALIYAFALMAVGKA
>Mature_710_residues
TEIGHGLLAHRTGAPVAEARPRRFSVHGQEIIDDYAWLKAENWQTVLKDPAALPDDIAAYLKAENAFAEAALAGSAELRR
QLVAEMRGRIQEDESGVPEPDGPFAYYTRHREGGQHPLICRRPATAPDVPESGPDPDETILIDGDREGEGLPFFEIAAAV
HSDDHARLAWSVDTKGSELYTIRVRDVATGLDLDDRVEATSGEAVWAADGASFWYVAVDANHRPAKVMRHRVGTGQSEDE
TVYTEADSGYFVHIGKTQSGAFLDVTVSDHETSEVRLLDRHAQDARLRLVEPRTPLLIYGVEHRGDRLFIRTNADGAEDF
KIVTAPLDDPGRAHWTDLVPHRSGVMIRHLHLLAGHLIRLEIENARPRIVVRDLADGTEHTVAFAEEAYSLGLRAGLAFD
TATIRFVYSSMTTPSETWDYDCAARTRLLRKRQVVPSGHDPAAYVTRRLFATAPDGEQVPISLLHRRDLALDGGAPLLLY
GYGSYGTLMPAAFRTNLLSLVDRGFVYAIAHIRGGTEKGWRWYLDGKREKKPNTFTDFIACARALIEARYTSEKRIVAHG
GSAGGMLMGAVANLAPELFAGIVADVPFVDVLNTMLDAELPLTPPEWPEWGNPGESETAFRTILSYSPYDNVAAKEYPAI
LALGGLTDPRVTYWEPAKWVARLRATMTGGGPVLLRINMEAGHGGAAGRFDRLEEVALIYAFALMAVGKA

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI284172438, Length=496, Percent_Identity=30.6451612903226, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI284172431, Length=496, Percent_Identity=30.6451612903226, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI284172420, Length=496, Percent_Identity=30.6451612903226, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI284172413, Length=496, Percent_Identity=30.6451612903226, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI70778815, Length=496, Percent_Identity=30.6451612903226, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI41349456, Length=721, Percent_Identity=24.1331484049931, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI108860686, Length=258, Percent_Identity=37.2093023255814, Blast_Score=146, Evalue=7e-35,
Organism=Homo sapiens, GI108860692, Length=237, Percent_Identity=37.1308016877637, Blast_Score=139, Evalue=8e-33,
Organism=Escherichia coli, GI1788150, Length=698, Percent_Identity=36.3896848137536, Blast_Score=409, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24583414, Length=723, Percent_Identity=25.7261410788382, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI221510989, Length=715, Percent_Identity=25.7342657342657, Blast_Score=188, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 78107; Mature: 77976

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIGHGLLAHRTGAPVAEARPRRFSVHGQEIIDDYAWLKAENWQTVLKDPAALPDDIAA
CCCCCCCHHHCCCCCCHHHCCCCEEECCHHHHHHHHHHEECCCCHHHHCCCCCCHHHHHH
YLKAENAFAEAALAGSAELRRQLVAEMRGRIQEDESGVPEPDGPFAYYTRHREGGQHPLI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEE
CRRPATAPDVPESGPDPDETILIDGDREGEGLPFFEIAAAVHSDDHARLAWSVDTKGSEL
EECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCEE
YTIRVRDVATGLDLDDRVEATSGEAVWAADGASFWYVAVDANHRPAKVMRHRVGTGQSED
EEEEEEEEECCCCCCCCCCCCCCCEEEEECCCEEEEEEEECCCCHHHHHHHHCCCCCCCC
ETVYTEADSGYFVHIGKTQSGAFLDVTVSDHETSEVRLLDRHAQDARLRLVEPRTPLLIY
CEEEEECCCCEEEEEECCCCCCEEEEEECCCCCCHHHEEHHCCCCCEEEEECCCCCEEEE
GVEHRGDRLFIRTNADGAEDFKIVTAPLDDPGRAHWTDLVPHRSGVMIRHLHLLAGHLIR
EEECCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHHCCCCCCCHHHHHHHHHHCEEEE
LEIENARPRIVVRDLADGTEHTVAFAEEAYSLGLRAGLAFDTATIRFVYSSMTTPSETWD
EEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEECCEEEEEEEECCCCCCCCCC
YDCAARTRLLRKRQVVPSGHDPAAYVTRRLFATAPDGEQVPISLLHRRDLALDGGAPLLL
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEECCCCCCCCHHHHHCCCCEECCCCCEEE
YGYGSYGTLMPAAFRTNLLSLVDRGFVYAIAHIRGGTEKGWRWYLDGKREKKPNTFTDFI
EEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCCCCCCHHHHHH
ACARALIEARYTSEKRIVAHGGSAGGMLMGAVANLAPELFAGIVADVPFVDVLNTMLDAE
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
LPLTPPEWPEWGNPGESETAFRTILSYSPYDNVAAKEYPAILALGGLTDPRVTYWEPAKW
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHCCCEEEEECCCCCCCEEEECHHHH
VARLRATMTGGGPVLLRINMEAGHGGAAGRFDRLEEVALIYAFALMAVGKA
HHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEIGHGLLAHRTGAPVAEARPRRFSVHGQEIIDDYAWLKAENWQTVLKDPAALPDDIAA
CCCCCCHHHCCCCCCHHHCCCCEEECCHHHHHHHHHHEECCCCHHHHCCCCCCHHHHHH
YLKAENAFAEAALAGSAELRRQLVAEMRGRIQEDESGVPEPDGPFAYYTRHREGGQHPLI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEE
CRRPATAPDVPESGPDPDETILIDGDREGEGLPFFEIAAAVHSDDHARLAWSVDTKGSEL
EECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCEE
YTIRVRDVATGLDLDDRVEATSGEAVWAADGASFWYVAVDANHRPAKVMRHRVGTGQSED
EEEEEEEEECCCCCCCCCCCCCCCEEEEECCCEEEEEEEECCCCHHHHHHHHCCCCCCCC
ETVYTEADSGYFVHIGKTQSGAFLDVTVSDHETSEVRLLDRHAQDARLRLVEPRTPLLIY
CEEEEECCCCEEEEEECCCCCCEEEEEECCCCCCHHHEEHHCCCCCEEEEECCCCCEEEE
GVEHRGDRLFIRTNADGAEDFKIVTAPLDDPGRAHWTDLVPHRSGVMIRHLHLLAGHLIR
EEECCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHHCCCCCCCHHHHHHHHHHCEEEE
LEIENARPRIVVRDLADGTEHTVAFAEEAYSLGLRAGLAFDTATIRFVYSSMTTPSETWD
EEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEECCEEEEEEEECCCCCCCCCC
YDCAARTRLLRKRQVVPSGHDPAAYVTRRLFATAPDGEQVPISLLHRRDLALDGGAPLLL
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEECCCCCCCCHHHHHCCCCEECCCCCEEE
YGYGSYGTLMPAAFRTNLLSLVDRGFVYAIAHIRGGTEKGWRWYLDGKREKKPNTFTDFI
EEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCCCCCCHHHHHH
ACARALIEARYTSEKRIVAHGGSAGGMLMGAVANLAPELFAGIVADVPFVDVLNTMLDAE
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
LPLTPPEWPEWGNPGESETAFRTILSYSPYDNVAAKEYPAILALGGLTDPRVTYWEPAKW
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHCCCEEEEECCCCCCCEEEECHHHH
VARLRATMTGGGPVLLRINMEAGHGGAAGRFDRLEEVALIYAFALMAVGKA
HHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]