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The map label for this gene is coaD

Identifier: 170748568

GI number: 170748568

Start: 2290374

End: 2290877

Strand: Reverse

Name: coaD

Synonym: Mrad2831_2150

Alternate gene names: 170748568

Gene position: 2290877-2290374 (Counterclockwise)

Preceding gene: 170748569

Following gene: 170748567

Centisome position: 37.69

GC content: 73.02

Gene sequence:

>504_bases
ATGACCCGCACCGCCCTCTACGCCGGCTCGTTCGATCCGGTCACGAACGGCCATCTCGACGTGGTCCGCCAAGCCTGCCG
GCTGGTGGACCGCCTCGTGATCGCCATCGGCGTCCATCCCGGCAAGGCGCCGCTGTTCTCCGCCGAGGAGCGCGCGGCGC
TCCTCACCGAGACCTGCGGACCGGTGGCACAGGCCGAGGGCGCGGCGCTGGAGATCGTCACCTTCAACGACCTCGCCGTC
TCGGCCGCCCGGCGCTGCGGCGCCGCGATCTTCATCCGCGGCCTGCGGGACGGCACGGATCTCGACTACGAGATGCAGCT
CGCCGGCATGAACGGCGCCATGGCGCCCGAGGTGCAGACCGTGTTCCTGCCCGCCTCGACGCAGGCCCGACCGATCACCG
CGACGCTGGTGCGCCAGATCGCCGGCATGGGGGGCGACGTCTCGCCCTTCGTGCCGGCGGCCGTCGCCGCGCGCCTCCGG
CAGCGCTTCGCCGCCCATTCCTGA

Upstream 100 bases:

>100_bases
GGCGAGGACGAGGGCGCCGAGGCCGGCCCCGAGGGCGGCGAGGAGGCGTGAGGCGCCGCCCGGTTCCGTCCGGCGCGAAA
ATGCTCTAGGTCGGGTCGCG

Downstream 100 bases:

>100_bases
GACCGGCCCGACCCTGGAAGGACCACGATGAACCGACGCCACGCCCTCCTCGCGCTCGCCCTCACGCTCGGCACCGTCCA
GGCCGCCCGGGCCGCCGACG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MTRTALYAGSFDPVTNGHLDVVRQACRLVDRLVIAIGVHPGKAPLFSAEERAALLTETCGPVAQAEGAALEIVTFNDLAV
SAARRCGAAIFIRGLRDGTDLDYEMQLAGMNGAMAPEVQTVFLPASTQARPITATLVRQIAGMGGDVSPFVPAAVAARLR
QRFAAHS

Sequences:

>Translated_167_residues
MTRTALYAGSFDPVTNGHLDVVRQACRLVDRLVIAIGVHPGKAPLFSAEERAALLTETCGPVAQAEGAALEIVTFNDLAV
SAARRCGAAIFIRGLRDGTDLDYEMQLAGMNGAMAPEVQTVFLPASTQARPITATLVRQIAGMGGDVSPFVPAAVAARLR
QRFAAHS
>Mature_166_residues
TRTALYAGSFDPVTNGHLDVVRQACRLVDRLVIAIGVHPGKAPLFSAEERAALLTETCGPVAQAEGAALEIVTFNDLAVS
AARRCGAAIFIRGLRDGTDLDYEMQLAGMNGAMAPEVQTVFLPASTQARPITATLVRQIAGMGGDVSPFVPAAVAARLRQ
RFAAHS

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=164, Percent_Identity=41.4634146341463, Blast_Score=139, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_METRJ (B1LVR4)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001754828.1
- ProteinModelPortal:   B1LVR4
- SMR:   B1LVR4
- GeneID:   6138182
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_2150
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17546; Mature: 17415

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTALYAGSFDPVTNGHLDVVRQACRLVDRLVIAIGVHPGKAPLFSAEERAALLTETCG
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCC
PVAQAEGAALEIVTFNDLAVSAARRCGAAIFIRGLRDGTDLDYEMQLAGMNGAMAPEVQT
CHHHCCCCEEEEEEECHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCEEE
VFLPASTQARPITATLVRQIAGMGGDVSPFVPAAVAARLRQRFAAHS
EEECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRTALYAGSFDPVTNGHLDVVRQACRLVDRLVIAIGVHPGKAPLFSAEERAALLTETCG
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCC
PVAQAEGAALEIVTFNDLAVSAARRCGAAIFIRGLRDGTDLDYEMQLAGMNGAMAPEVQT
CHHHCCCCEEEEEEECHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCEEE
VFLPASTQARPITATLVRQIAGMGGDVSPFVPAAVAARLRQRFAAHS
EEECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA