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The map label for this gene is metH [H]

Identifier: 170748541

GI number: 170748541

Start: 2260261

End: 2264013

Strand: Reverse

Name: metH [H]

Synonym: Mrad2831_2123

Alternate gene names: 170748541

Gene position: 2264013-2260261 (Counterclockwise)

Preceding gene: 170748542

Following gene: 170748536

Centisome position: 37.25

GC content: 67.68

Gene sequence:

>3753_bases
ATGACCGATTTTGCCCCCGTCGACGGCACCGAGATCGCGAAGGCCCTGCGCCAGCGCGCGGCGGAAAAGATCCTCGTCCT
CGACGGGGCGATGGGCACCGTGATCCAGCGGCTGAAGTTCTCGGAAGAGGATTTCCGCGGCGACCGGTTCAAGGATCACG
GCCACGATCAGAAGGGCAACAACGACCTCCTGATCCTGACCCAGCCCGACGCGATCCGGCAGATCCACCTCGACTACTTC
CTGGCCGGCGCCGACGTCTGCGAGACCAACACCTTCTCGGGCACCACCATCGCCCAGGCCGATTACGGCATGGAGTCGAT
CATCCACGAGCTGAACGCCGAGGGCGCAAGGCTCGCCCGTGAGGCCGCCAAGCTCGCCGAGCAGAAGGACGGACGCCGCC
GCTTCGTGGCCGGCGCCATCGGCCCGACGAACCGGACTTTGTCGATCTCGCCGGACGTGAACAACCCGGGCTTCCGGGCC
GTCACCTTCGATCAGGTCAAGCAGGCTTACGTGGAGCAGGTCCGCGGCCTGATCGACGGCGGTGCCGAGCTGATCCTGAT
CGAGACCATCTTCGACACGCTGAACGCCAAGGCCGCAGTGGCGGCGGCGTGGCAAGTCTTCGACGAGACCGGCATCCGCC
TGCCGATCCAGATCTCCGGCACGATCACGGATCTCTCGGGCCGCACCCTGTCGGGCCAGACCCCGGCGGCCTTCTGGCAC
TCCCTGCGCCATTCCGAGCCGCTGACCTTCGGCCTCAACTGCGCGCTCGGTGCCCGCGAGATGCGCGGCCACATCGCCGA
GCTGTCGCGGATCTGCGATACCCTGGTCTGCGCCTACCCGAATGCCGGCCTGCCGAACGAGTTCGGCCTCTACGACGAGA
GTCCGGAGGCGATGGGCAAGCTGGTCGGCGAGTTCGCCGAATCCGGCCTCGTCAACATGGTCGGCGGCTGCTGCGGCACC
ACCCCGGACCACATCCGCGCCATCGCGGAGGCCGTCGCCGGCAAGGCGCCGCGGCCGATCCCCGAGGTGCCGCGCCTGAT
GCGGCTCTCGGGCCTGGAGCCCTTCGTCCTCACGCCAGAAATCCCCTTCGTGAACGTGGGCGAGCGCACGAACGTCACCG
GCTCGGCCAAATTCCGCAAGCTCATCACCAACGGCGACTACGCGGCGGCGCTCGACGTCGCCCGCGATCAGGTGGCAGCC
GGCGCCCAGGTGATCGACGTCAACATGGACGAGGGCCTGCTCGACTCCCAGAAGGCGATGGTCGAGTTCCTGAACCTCGT
CGCCGCCGAGCCCGACATCGCCCGGGTGCCCGTGATGGTCGATTCCTCGAAGTTCGAGGTGATCGAGGCCGGCCTGAAGT
GCATCCAGGGCAAGCCGATCGTGAACTCGATCTCGATGAAGGAGGGCGAGGAGAAGTTCATCGAGGCCGCCAAGGTCTGC
CGCTCCTACGGGGCCGCCGTGGTGGTGATGGCCTTCGACGAGCAGGGGCAGGCGGATTCCTACGAGCGCAAGGTCGAGAT
CTGCACCAAGGCCTACCGGATCCTGACCGAGCAGGTCGGCTTCCCGCCCGAGGACATCATCTTCGATCCGAACATCTTCG
CCGTCGCCACCGGTATCGAGGAACACAACCCGTACGGCGTGGCCTTCATCGAGGCGACCCGCACGATCCGCGAGACCCTG
CCGCACGCCCATATCTCGGGCGGCGTCTCGAACCTGTCCTTCGCGTTCCGCGGCAACGAGCCGGTGCGCGAGGCGATGCA
CGCGGTGTTCCTGTTCCACTGCATCAAGGCCGGCATGGACATGGGCATCGTCAATGCCGGCCAGCTCGCCGTGTATGACG
AGATCCCGGCGGAGCTGCGCGAGCTGTGCGAGGACGTGGTCCTCAACCGCCGCGACGATTCCACCGAGCGCCTGCTGGAG
GCCGCCGAGCGCTTCAAGACCGGCGCCTCGGCCCAGGCCAAGACCGCCGACCTGACGTGGCGCGAGGCGCCCGTCGAGAA
GCGCATCGAGCACGCGCTGGTCAACGGCATCACCGAGTACATCGTGGCCGACACCGAGGAGGCGCGACAGAAGGCCGAGC
GCCCGCTCCACGTCATCGAGGGCCCGCTGATGGCCGGCATGAACGTGGTCGGCGACCTGTTCGGCTCCGGAAAGATGTTC
CTGCCCCAAGTCGTGAAGTCGGCCCGCGTGATGAAGCAGGCGGTCGCCTATCTCGAGCCGTTCATGGAGGAGGAGAAGCG
CGCCAACGGCGGCGACGGCAAGCGACAGGCCGCCGGCAAGGTGCTGATGGCCACCGTGAAGGGCGACGTCCACGACATCG
GCAAGAACATCGTCGGCGTCGTGCTGGCCTGCAACAACTACGAGATCATCGATCTCGGCGTGATGGTGCCGGCCGCCAAG
ATCCTGGAGACCGCCAAGACCGAGAAGGTCGACATCGTCGGCCTGTCCGGCCTGATCACACCGTCGCTCGATGAGATGGT
CCACGTGGCGGGCGAGATGGAGCGCGAGGGTCTCGACGTGCCGCTGCTGATCGGCGGCGCCACCACGAGCCGCGTCCACA
CGGCGGTGAAGATCCACCCGGCCTACGCCAAGGGTCAGGCGGTCTACGTCACCGACGCGAGCCGCGCGGTCGGCGTGGTC
TCGAGCCTGATCTCCAAAGAGACCCGCGGCGCCACGATCGAGAAGGTCCGGGCCGAGTACGCCAAGGTCGCCGACGCCCA
CAAGCGGTCGGAGGCCGACAAGCAGCGGCTCCCGCTCGCCAAGGCGCGGACCAACGCGTTCAAGATCGACTGGTCGGCCT
ACAAGCCGGCCAAGCCCAGCTTCACCGGCACCCGGGTCTACGGCTCCTACGAGGTCGCGGACCTCGTGCCCTACATCGAC
TGGACGCCGTTCCTGCAGACCTACGAGTTCAAGGGCCGCTTCCCGGCGATCCTGGACGACCCGGAGCAGGGCCCGGCCGC
CCGCGCCCTCTACGAGGACGCGCAAGGCATGCTGAAGCAGATCGTGGAGGAGCGCTGGTTCAACCCGAAGGCGGTGATCG
GCTTCTGGCCGGCCAACAGCGTCGGCGACGACATCGCGCTCTACACCGGCGAGAGCCGGTCGGAGCGGCTCGCCACCTTC
CACGGCCTGCGCCAGCAGCTCTCGAAGCGCGACGGGCGGTCGAACACCTGCCTGTCGGACTTCGTGGCGCCGGCCGAGAC
CGGCATTGCCGATTATGTCGGCGGCTTCGTGGTCACGGCGGGTCTGGAGGAGGTGCGGATCGCCGAGCGCTTCGAGCGGG
CGAACGACGATTACCGGGCGATCCTCGTGAAGGCGCTCGCCGACCGCATCGCCGAGGCCTTCGCCGAGCGGATGCACGAG
CGGGTGCGCAAGGAGTTCTGGGGCTACGCGGCCGACGAGGCCTACGGCCCCGATGAGCTGGTGCTGGAGAAGTACGACGG
CATCCGCCCAGCCCCGGGCTACCCGGCCCAGCCCGACCACACCGAGAAGACCACGCTGTTCGATCTGCTGAAGGCCGAGA
GGCGGATCGGCGTGAAGCTGACCGAGTCTTATGCGATGTGGCCGGGCTCGTCGGTGTCGGGGATCTACATCGCCCACCCG
GAGGCGCACTATTTCGGCGTCGCCAAGGTGGAGCGGGATCAGGTCGAGGATTACGCCGCCCGCAAGGGGATGGACATCCG
AGAGGTCGAGCGCTGGCTCGGGCCGATCCTGAACTACGACCCGGCGCGGTATCTCGCGCAGGCGGCGGAGTAG

Upstream 100 bases:

>100_bases
GAAGGAGGGTTTCAGGGAACACCGAGATATCAGGCGGCCTCCTGCGAGGCCTCCGCTTCGCTCCGGCACCTCGGGACGAG
GTGATCTGACAGGACGCACG

Downstream 100 bases:

>100_bases
GGGCGGGGCACCATCATCGCGAGCGGGGCGAAGCGACCCAGGGTCAGCGCGACATTGGTCAGCGTGGCGCTACCCTGGAT
TGCTTCGCTCCGCCCGCGAG

Product: B12-dependent methionine synthase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1250; Mature: 1249

Protein sequence:

>1250_residues
MTDFAPVDGTEIAKALRQRAAEKILVLDGAMGTVIQRLKFSEEDFRGDRFKDHGHDQKGNNDLLILTQPDAIRQIHLDYF
LAGADVCETNTFSGTTIAQADYGMESIIHELNAEGARLAREAAKLAEQKDGRRRFVAGAIGPTNRTLSISPDVNNPGFRA
VTFDQVKQAYVEQVRGLIDGGAELILIETIFDTLNAKAAVAAAWQVFDETGIRLPIQISGTITDLSGRTLSGQTPAAFWH
SLRHSEPLTFGLNCALGAREMRGHIAELSRICDTLVCAYPNAGLPNEFGLYDESPEAMGKLVGEFAESGLVNMVGGCCGT
TPDHIRAIAEAVAGKAPRPIPEVPRLMRLSGLEPFVLTPEIPFVNVGERTNVTGSAKFRKLITNGDYAAALDVARDQVAA
GAQVIDVNMDEGLLDSQKAMVEFLNLVAAEPDIARVPVMVDSSKFEVIEAGLKCIQGKPIVNSISMKEGEEKFIEAAKVC
RSYGAAVVVMAFDEQGQADSYERKVEICTKAYRILTEQVGFPPEDIIFDPNIFAVATGIEEHNPYGVAFIEATRTIRETL
PHAHISGGVSNLSFAFRGNEPVREAMHAVFLFHCIKAGMDMGIVNAGQLAVYDEIPAELRELCEDVVLNRRDDSTERLLE
AAERFKTGASAQAKTADLTWREAPVEKRIEHALVNGITEYIVADTEEARQKAERPLHVIEGPLMAGMNVVGDLFGSGKMF
LPQVVKSARVMKQAVAYLEPFMEEEKRANGGDGKRQAAGKVLMATVKGDVHDIGKNIVGVVLACNNYEIIDLGVMVPAAK
ILETAKTEKVDIVGLSGLITPSLDEMVHVAGEMEREGLDVPLLIGGATTSRVHTAVKIHPAYAKGQAVYVTDASRAVGVV
SSLISKETRGATIEKVRAEYAKVADAHKRSEADKQRLPLAKARTNAFKIDWSAYKPAKPSFTGTRVYGSYEVADLVPYID
WTPFLQTYEFKGRFPAILDDPEQGPAARALYEDAQGMLKQIVEERWFNPKAVIGFWPANSVGDDIALYTGESRSERLATF
HGLRQQLSKRDGRSNTCLSDFVAPAETGIADYVGGFVVTAGLEEVRIAERFERANDDYRAILVKALADRIAEAFAERMHE
RVRKEFWGYAADEAYGPDELVLEKYDGIRPAPGYPAQPDHTEKTTLFDLLKAERRIGVKLTESYAMWPGSSVSGIYIAHP
EAHYFGVAKVERDQVEDYAARKGMDIREVERWLGPILNYDPARYLAQAAE

Sequences:

>Translated_1250_residues
MTDFAPVDGTEIAKALRQRAAEKILVLDGAMGTVIQRLKFSEEDFRGDRFKDHGHDQKGNNDLLILTQPDAIRQIHLDYF
LAGADVCETNTFSGTTIAQADYGMESIIHELNAEGARLAREAAKLAEQKDGRRRFVAGAIGPTNRTLSISPDVNNPGFRA
VTFDQVKQAYVEQVRGLIDGGAELILIETIFDTLNAKAAVAAAWQVFDETGIRLPIQISGTITDLSGRTLSGQTPAAFWH
SLRHSEPLTFGLNCALGAREMRGHIAELSRICDTLVCAYPNAGLPNEFGLYDESPEAMGKLVGEFAESGLVNMVGGCCGT
TPDHIRAIAEAVAGKAPRPIPEVPRLMRLSGLEPFVLTPEIPFVNVGERTNVTGSAKFRKLITNGDYAAALDVARDQVAA
GAQVIDVNMDEGLLDSQKAMVEFLNLVAAEPDIARVPVMVDSSKFEVIEAGLKCIQGKPIVNSISMKEGEEKFIEAAKVC
RSYGAAVVVMAFDEQGQADSYERKVEICTKAYRILTEQVGFPPEDIIFDPNIFAVATGIEEHNPYGVAFIEATRTIRETL
PHAHISGGVSNLSFAFRGNEPVREAMHAVFLFHCIKAGMDMGIVNAGQLAVYDEIPAELRELCEDVVLNRRDDSTERLLE
AAERFKTGASAQAKTADLTWREAPVEKRIEHALVNGITEYIVADTEEARQKAERPLHVIEGPLMAGMNVVGDLFGSGKMF
LPQVVKSARVMKQAVAYLEPFMEEEKRANGGDGKRQAAGKVLMATVKGDVHDIGKNIVGVVLACNNYEIIDLGVMVPAAK
ILETAKTEKVDIVGLSGLITPSLDEMVHVAGEMEREGLDVPLLIGGATTSRVHTAVKIHPAYAKGQAVYVTDASRAVGVV
SSLISKETRGATIEKVRAEYAKVADAHKRSEADKQRLPLAKARTNAFKIDWSAYKPAKPSFTGTRVYGSYEVADLVPYID
WTPFLQTYEFKGRFPAILDDPEQGPAARALYEDAQGMLKQIVEERWFNPKAVIGFWPANSVGDDIALYTGESRSERLATF
HGLRQQLSKRDGRSNTCLSDFVAPAETGIADYVGGFVVTAGLEEVRIAERFERANDDYRAILVKALADRIAEAFAERMHE
RVRKEFWGYAADEAYGPDELVLEKYDGIRPAPGYPAQPDHTEKTTLFDLLKAERRIGVKLTESYAMWPGSSVSGIYIAHP
EAHYFGVAKVERDQVEDYAARKGMDIREVERWLGPILNYDPARYLAQAAE
>Mature_1249_residues
TDFAPVDGTEIAKALRQRAAEKILVLDGAMGTVIQRLKFSEEDFRGDRFKDHGHDQKGNNDLLILTQPDAIRQIHLDYFL
AGADVCETNTFSGTTIAQADYGMESIIHELNAEGARLAREAAKLAEQKDGRRRFVAGAIGPTNRTLSISPDVNNPGFRAV
TFDQVKQAYVEQVRGLIDGGAELILIETIFDTLNAKAAVAAAWQVFDETGIRLPIQISGTITDLSGRTLSGQTPAAFWHS
LRHSEPLTFGLNCALGAREMRGHIAELSRICDTLVCAYPNAGLPNEFGLYDESPEAMGKLVGEFAESGLVNMVGGCCGTT
PDHIRAIAEAVAGKAPRPIPEVPRLMRLSGLEPFVLTPEIPFVNVGERTNVTGSAKFRKLITNGDYAAALDVARDQVAAG
AQVIDVNMDEGLLDSQKAMVEFLNLVAAEPDIARVPVMVDSSKFEVIEAGLKCIQGKPIVNSISMKEGEEKFIEAAKVCR
SYGAAVVVMAFDEQGQADSYERKVEICTKAYRILTEQVGFPPEDIIFDPNIFAVATGIEEHNPYGVAFIEATRTIRETLP
HAHISGGVSNLSFAFRGNEPVREAMHAVFLFHCIKAGMDMGIVNAGQLAVYDEIPAELRELCEDVVLNRRDDSTERLLEA
AERFKTGASAQAKTADLTWREAPVEKRIEHALVNGITEYIVADTEEARQKAERPLHVIEGPLMAGMNVVGDLFGSGKMFL
PQVVKSARVMKQAVAYLEPFMEEEKRANGGDGKRQAAGKVLMATVKGDVHDIGKNIVGVVLACNNYEIIDLGVMVPAAKI
LETAKTEKVDIVGLSGLITPSLDEMVHVAGEMEREGLDVPLLIGGATTSRVHTAVKIHPAYAKGQAVYVTDASRAVGVVS
SLISKETRGATIEKVRAEYAKVADAHKRSEADKQRLPLAKARTNAFKIDWSAYKPAKPSFTGTRVYGSYEVADLVPYIDW
TPFLQTYEFKGRFPAILDDPEQGPAARALYEDAQGMLKQIVEERWFNPKAVIGFWPANSVGDDIALYTGESRSERLATFH
GLRQQLSKRDGRSNTCLSDFVAPAETGIADYVGGFVVTAGLEEVRIAERFERANDDYRAILVKALADRIAEAFAERMHER
VRKEFWGYAADEAYGPDELVLEKYDGIRPAPGYPAQPDHTEKTTLFDLLKAERRIGVKLTESYAMWPGSSVSGIYIAHPE
AHYFGVAKVERDQVEDYAARKGMDIREVERWLGPILNYDPARYLAQAAE

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1252, Percent_Identity=55.0319488817891, Blast_Score=1376, Evalue=0.0,
Organism=Escherichia coli, GI1790450, Length=1230, Percent_Identity=61.3008130081301, Blast_Score=1512, Evalue=0.0,
Organism=Escherichia coli, GI1786456, Length=319, Percent_Identity=26.6457680250784, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17535405, Length=1249, Percent_Identity=54.5236188951161, Blast_Score=1346, Evalue=0.0,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 136891; Mature: 136760

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFAPVDGTEIAKALRQRAAEKILVLDGAMGTVIQRLKFSEEDFRGDRFKDHGHDQKGN
CCCCCCCCHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCC
NDLLILTQPDAIRQIHLDYFLAGADVCETNTFSGTTIAQADYGMESIIHELNAEGARLAR
CCEEEEECCHHHHHHHHHHHEECCCHHCCCCCCCCEEEHHHCCHHHHHHHHCCCHHHHHH
EAAKLAEQKDGRRRFVAGAIGPTNRTLSISPDVNNPGFRAVTFDQVKQAYVEQVRGLIDG
HHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHCC
GAELILIETIFDTLNAKAAVAAAWQVFDETGIRLPIQISGTITDLSGRTLSGQTPAAFWH
CCCEEEHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCEECCCCHHHHHH
SLRHSEPLTFGLNCALGAREMRGHIAELSRICDTLVCAYPNAGLPNEFGLYDESPEAMGK
HHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
LVGEFAESGLVNMVGGCCGTTPDHIRAIAEAVAGKAPRPIPEVPRLMRLSGLEPFVLTPE
HHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEECCC
IPFVNVGERTNVTGSAKFRKLITNGDYAAALDVARDQVAAGAQVIDVNMDEGLLDSQKAM
CCEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHH
VEFLNLVAAEPDIARVPVMVDSSKFEVIEAGLKCIQGKPIVNSISMKEGEEKFIEAAKVC
HHHHHHHHCCCCCEECCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
RSYGAAVVVMAFDEQGQADSYERKVEICTKAYRILTEQVGFPPEDIIFDPNIFAVATGIE
HHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCEEEEEECCC
EHNPYGVAFIEATRTIRETLPHAHISGGVSNLSFAFRGNEPVREAMHAVFLFHCIKAGMD
CCCCCEEEEHHHHHHHHHHCCCHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCC
MGIVNAGQLAVYDEIPAELRELCEDVVLNRRDDSTERLLEAAERFKTGASAQAKTADLTW
CCCCCCCCEEEEHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCH
REAPVEKRIEHALVNGITEYIVADTEEARQKAERPLHVIEGPLMAGMNVVGDLFGSGKMF
HHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCCCH
LPQVVKSARVMKQAVAYLEPFMEEEKRANGGDGKRQAAGKVLMATVKGDVHDIGKNIVGV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCEEEEECCCCHHHHHHHHEEE
VLACNNYEIIDLGVMVPAAKILETAKTEKVDIVGLSGLITPSLDEMVHVAGEMEREGLDV
EEEECCEEEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCC
PLLIGGATTSRVHTAVKIHPAYAKGQAVYVTDASRAVGVVSSLISKETRGATIEKVRAEY
EEEECCCCHHHEEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHH
AKVADAHKRSEADKQRLPLAKARTNAFKIDWSAYKPAKPSFTGTRVYGSYEVADLVPYID
HHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCCCCCCEEEECCEEHHHHHCCCC
WTPFLQTYEFKGRFPAILDDPEQGPAARALYEDAQGMLKQIVEERWFNPKAVIGFWPANS
CCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
VGDDIALYTGESRSERLATFHGLRQQLSKRDGRSNTCLSDFVAPAETGIADYVGGFVVTA
CCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHCCHHHHHCHHEEEC
GLEEVRIAERFERANDDYRAILVKALADRIAEAFAERMHERVRKEFWGYAADEAYGPDEL
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
VLEKYDGIRPAPGYPAQPDHTEKTTLFDLLKAERRIGVKLTESYAMWPGSSVSGIYIAHP
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCEEECCCCCCCEEEEECC
EAHYFGVAKVERDQVEDYAARKGMDIREVERWLGPILNYDPARYLAQAAE
CCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
TDFAPVDGTEIAKALRQRAAEKILVLDGAMGTVIQRLKFSEEDFRGDRFKDHGHDQKGN
CCCCCCCHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCC
NDLLILTQPDAIRQIHLDYFLAGADVCETNTFSGTTIAQADYGMESIIHELNAEGARLAR
CCEEEEECCHHHHHHHHHHHEECCCHHCCCCCCCCEEEHHHCCHHHHHHHHCCCHHHHHH
EAAKLAEQKDGRRRFVAGAIGPTNRTLSISPDVNNPGFRAVTFDQVKQAYVEQVRGLIDG
HHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHCC
GAELILIETIFDTLNAKAAVAAAWQVFDETGIRLPIQISGTITDLSGRTLSGQTPAAFWH
CCCEEEHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCEECCCCHHHHHH
SLRHSEPLTFGLNCALGAREMRGHIAELSRICDTLVCAYPNAGLPNEFGLYDESPEAMGK
HHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
LVGEFAESGLVNMVGGCCGTTPDHIRAIAEAVAGKAPRPIPEVPRLMRLSGLEPFVLTPE
HHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEECCC
IPFVNVGERTNVTGSAKFRKLITNGDYAAALDVARDQVAAGAQVIDVNMDEGLLDSQKAM
CCEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHH
VEFLNLVAAEPDIARVPVMVDSSKFEVIEAGLKCIQGKPIVNSISMKEGEEKFIEAAKVC
HHHHHHHHCCCCCEECCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
RSYGAAVVVMAFDEQGQADSYERKVEICTKAYRILTEQVGFPPEDIIFDPNIFAVATGIE
HHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCEEEEEECCC
EHNPYGVAFIEATRTIRETLPHAHISGGVSNLSFAFRGNEPVREAMHAVFLFHCIKAGMD
CCCCCEEEEHHHHHHHHHHCCCHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCC
MGIVNAGQLAVYDEIPAELRELCEDVVLNRRDDSTERLLEAAERFKTGASAQAKTADLTW
CCCCCCCCEEEEHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCH
REAPVEKRIEHALVNGITEYIVADTEEARQKAERPLHVIEGPLMAGMNVVGDLFGSGKMF
HHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCCCH
LPQVVKSARVMKQAVAYLEPFMEEEKRANGGDGKRQAAGKVLMATVKGDVHDIGKNIVGV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCEEEEECCCCHHHHHHHHEEE
VLACNNYEIIDLGVMVPAAKILETAKTEKVDIVGLSGLITPSLDEMVHVAGEMEREGLDV
EEEECCEEEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCC
PLLIGGATTSRVHTAVKIHPAYAKGQAVYVTDASRAVGVVSSLISKETRGATIEKVRAEY
EEEECCCCHHHEEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHH
AKVADAHKRSEADKQRLPLAKARTNAFKIDWSAYKPAKPSFTGTRVYGSYEVADLVPYID
HHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCCCCCCEEEECCEEHHHHHCCCC
WTPFLQTYEFKGRFPAILDDPEQGPAARALYEDAQGMLKQIVEERWFNPKAVIGFWPANS
CCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
VGDDIALYTGESRSERLATFHGLRQQLSKRDGRSNTCLSDFVAPAETGIADYVGGFVVTA
CCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHCCHHHHHCHHEEEC
GLEEVRIAERFERANDDYRAILVKALADRIAEAFAERMHERVRKEFWGYAADEAYGPDEL
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
VLEKYDGIRPAPGYPAQPDHTEKTTLFDLLKAERRIGVKLTESYAMWPGSSVSGIYIAHP
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCEEECCCCCCCEEEEECC
EAHYFGVAKVERDQVEDYAARKGMDIREVERWLGPILNYDPARYLAQAAE
CCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]