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The map label for this gene is nuoC

Identifier: 170748476

GI number: 170748476

Start: 2189310

End: 2189957

Strand: Reverse

Name: nuoC

Synonym: Mrad2831_2058

Alternate gene names: 170748476

Gene position: 2189957-2189310 (Counterclockwise)

Preceding gene: 170748477

Following gene: 170748475

Centisome position: 36.03

GC content: 66.82

Gene sequence:

>648_bases
ATGACGAACGGCATCTCGATCCTGCCCCACACCCAGCCGGTCTACGGCGACGCGGCCGTGGCTGCCATGGCCGAGCGCGT
CGTCGGCGCCCTCGGACCGGCGGTGGTGTCCCACGCCATCGCGTTCGGCGAGCTGACGCTGGTGGTCCAGGCCTCCGACA
TCGTCTACGCGCTCACCTACCTGCGCGACGATCCGGCCTGCGCGTTCCGCAACTTCATCGACATATGCGGCGTGGACTAT
CCGCAGCGCGAGAAGCGCTTCGACGTGGTCTACCACCTGCTCTCCCTGCGCCATAACCTGCGCATCCGGCTGAAGGTGCA
GACCGACGAGGTGACGCCGGTCCCCTCGGTGATCGAGGTCTTCCCGGCGGCCAACTGGTACGAGCGCGAGACCTACGACC
TCTACGGGATCCTGTTCTCGGGCCATCCCGACCTGCGCCGCCTGCTCACCGATTACGGCTTCGAGGGGCATCCCCTGCGC
AAGGACTTCCCGCTCACCGGCTTCGTCGAGGTCCGCTACGACCAGGACCAGGCGCGGGTGGTCTACGAGCCGGTGCAGCT
GACGCAGGAATTCCGGAACTTCGACTTCTTGTCGCCGTGGGAAGGCACCGACTACGTGCTGCCCGGCGACGAGAAGACGT
CGGCATGA

Upstream 100 bases:

>100_bases
GCCCGGCTGCCCGCCCACCGCCGAGGCGCTGCTCTACGGCGTGCTGCTGCTGCAGAAGAAGATCCGCCGGACCGGCACGA
TCGAGCGCTGAGGAGCGGCC

Downstream 100 bases:

>100_bases
GCCGCGGAGACCGTCCGTGACCGAACACAACATCCGCAACTTCGCGATCAACTTCGGCCCGCAGCACCCGGCGGCGCACG
GGGTGCTGCGCCTCGTGCTC

Product: NADH (or F420H2) dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MTNGISILPHTQPVYGDAAVAAMAERVVGALGPAVVSHAIAFGELTLVVQASDIVYALTYLRDDPACAFRNFIDICGVDY
PQREKRFDVVYHLLSLRHNLRIRLKVQTDEVTPVPSVIEVFPAANWYERETYDLYGILFSGHPDLRRLLTDYGFEGHPLR
KDFPLTGFVEVRYDQDQARVVYEPVQLTQEFRNFDFLSPWEGTDYVLPGDEKTSA

Sequences:

>Translated_215_residues
MTNGISILPHTQPVYGDAAVAAMAERVVGALGPAVVSHAIAFGELTLVVQASDIVYALTYLRDDPACAFRNFIDICGVDY
PQREKRFDVVYHLLSLRHNLRIRLKVQTDEVTPVPSVIEVFPAANWYERETYDLYGILFSGHPDLRRLLTDYGFEGHPLR
KDFPLTGFVEVRYDQDQARVVYEPVQLTQEFRNFDFLSPWEGTDYVLPGDEKTSA
>Mature_214_residues
TNGISILPHTQPVYGDAAVAAMAERVVGALGPAVVSHAIAFGELTLVVQASDIVYALTYLRDDPACAFRNFIDICGVDYP
QREKRFDVVYHLLSLRHNLRIRLKVQTDEVTPVPSVIEVFPAANWYERETYDLYGILFSGHPDLRRLLTDYGFEGHPLRK
DFPLTGFVEVRYDQDQARVVYEPVQLTQEFRNFDFLSPWEGTDYVLPGDEKTSA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=162, Percent_Identity=56.7901234567901, Blast_Score=210, Evalue=7e-55,
Organism=Escherichia coli, GI145693162, Length=142, Percent_Identity=38.0281690140845, Blast_Score=94, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71990788, Length=161, Percent_Identity=52.1739130434783, Blast_Score=191, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI32563621, Length=158, Percent_Identity=52.5316455696203, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24656494, Length=161, Percent_Identity=57.7639751552795, Blast_Score=206, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_METRJ (B1LUN5)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001754736.1
- ProteinModelPortal:   B1LUN5
- SMR:   B1LUN5
- GeneID:   6138087
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_2058
- HOGENOM:   HBG727675
- OMA:   VVYEPVR
- ProtClustDB:   CLSK2330536
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 24387; Mature: 24256

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNGISILPHTQPVYGDAAVAAMAERVVGALGPAVVSHAIAFGELTLVVQASDIVYALTY
CCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECHHHEEEEH
LRDDPACAFRNFIDICGVDYPQREKRFDVVYHLLSLRHNLRIRLKVQTDEVTPVPSVIEV
HCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHH
FPAANWYERETYDLYGILFSGHPDLRRLLTDYGFEGHPLRKDFPLTGFVEVRYDQDQARV
HCCCCCCCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEE
VYEPVQLTQEFRNFDFLSPWEGTDYVLPGDEKTSA
EEHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
TNGISILPHTQPVYGDAAVAAMAERVVGALGPAVVSHAIAFGELTLVVQASDIVYALTY
CCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECHHHEEEEH
LRDDPACAFRNFIDICGVDYPQREKRFDVVYHLLSLRHNLRIRLKVQTDEVTPVPSVIEV
HCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHH
FPAANWYERETYDLYGILFSGHPDLRRLLTDYGFEGHPLRKDFPLTGFVEVRYDQDQARV
HCCCCCCCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEE
VYEPVQLTQEFRNFDFLSPWEGTDYVLPGDEKTSA
EEHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA