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The map label for this gene is 170748462

Identifier: 170748462

GI number: 170748462

Start: 2172708

End: 2174381

Strand: Reverse

Name: 170748462

Synonym: Mrad2831_2044

Alternate gene names: NA

Gene position: 2174381-2172708 (Counterclockwise)

Preceding gene: 170748463

Following gene: 170748461

Centisome position: 35.78

GC content: 70.85

Gene sequence:

>1674_bases
ATGGTTAAAGGACAGGAGGAGCTGGTCTTCCTGCCGCTCGGCGGCGTGGGCGAGATCGGGATGAACGCGGCGCTCTACGG
GTTCGGCCCGGAGAAGGGCCGGAAGTGGATCATGGTCGATTGCGGCATGGGCTTCGCCGGCGAGGAGCAGATGCCCGGCG
TCGACCTGATGTTCCCCGACCTCTCCTTCATCGAGGAGCGGCGCAAGGATCTGCTGGGGATCTTCATCACCCACGCGCAC
GAGGACCATATCGGGGCGATCTCGGAACTGTGGCCCCGGCTCAAGGCGCCGGTCTACGCGACCCGCTTCGCCAAGAACCT
GCTGGAGACCCGGCGCCTCTCCGAGCCCGGCGCCCCGAAGGTCGAGCTGCGGGAGGTGAAGCCCGGCCGGCGCGTGACCG
TCGGCCCGTTCGAGCTCGAGTACGTGCCGGTCTCGCACTCCATCCCGGAATCGAACGCCATCGCCATCCGCACGGCGGCC
GGTCTCGTCCTCCACACCGGCGACTGGAAGATCGACCCGACCCCGGTGGCCGGCTCCGTGACGTCGCCGGAGGCGTTCAC
GGCGCTCGGGGACGAGGGCGTTCTCGCGATCGTGTGCGACTCGACCAACGTCGTGCGCGAGGGCTTCTCGCCGAGCGAGA
AGACCGTCGCCGAGACCCTGAAGACGCTGATCGCGGACGCGCCGCACCGGGTCGCGGTGACGACCTTCGCGTCGAACGTG
GCCCGCATCCGCGCGGTCGCCGAGGCCGCCGCCGCCTGCGGGCGCGAGGTCATCGCGGTCGGGCGCGCCATGGACCGGGT
GATCGACGTCGCCCGCGAGTGCGGCTACCTCGACGGCCTGCCCGAGTTCCGCCGCTCGGATTCGTGGAAGAGCCTGCCCC
GGGAGCGCGTCGTCGCCCTGCTCACCGGCTCCCAGGGCGAGCCGCGGGCGGCGCTCGCCCGCGTCTCCCGCCGCGACCAC
CCGGATATCAGCCTCACCGCCGGCGACCAGGTGATCTTCTCCTCGCGCGCCATCCCGGGCAACGAGCGCGATGTCGGATC
GATCATCAACGACCTGATCGAGCAGGGCGTCGAGGTGATCACCGACCGCACCGACCTCGTCCACGTCTCCGGCCACCCGC
GCCGGGACGAGATGGTCGAGATGTACCGGTGGACCCGCCCGGGCACCGCGATCCCGGTCCACGGCGAGGCCCTGCACCTC
GACGAGCATGCCCGCTTCGCCCGGGCGCAGGGCGTGCAGAACGTGGTCAAGGCCCGCAACGGCAGCCTGATCCGCCTGAG
CCCCGGCAAGCCCGAGGTGATCGACCACGTGAAGGCCGGCCGCCTGTTCAAGGACGGCGACGTCCTGATCGACGAGAAGG
ACCGGGCGATCCCGGAGCGGCGCAAGCTGATGCAGGCCGGCCTGGTCTCGGTGGCGATCGCCATCGACGAGGACGGCGTC
GTGCTCGGCGAGCCGGCCGTGGACATCATCGGCCTGCCGAACCGCGGCCGGTCCGGGGAGCCGCTGATCGAGACCGTGGT
GGACGCGGTCTCCCGCACCCTCTCGGGGATGTCGCGGGGCAAGCTGAAGGACTCGGAGAGCGTCGAGAAGACGGTCGACC
GGGCCGTGCGCACCGCGGTCAACGAGGTGTGGGGCAAGAAGCCGGCCTGCCACGTGCAGGTGGTGGAGGTGTGA

Upstream 100 bases:

>100_bases
CTCGTGATCCTCGCCCCCGATGGGAACCGGCATACCGTGACGGCGGGCGAGGTGCATTTCGGATCGGCCGCGACGGCGGC
CTGAGTTTGGACGACGACAG

Downstream 100 bases:

>100_bases
GGCTGGCTGCCGATCGCGAGGCGCTGTAATCTGCAGCGCTTCGAGACAGCTGAAGTCTCTCATCGTCGGCCGGAGAAGAC
ACAGATTCCCTCTCCCGCGC

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MVKGQEELVFLPLGGVGEIGMNAALYGFGPEKGRKWIMVDCGMGFAGEEQMPGVDLMFPDLSFIEERRKDLLGIFITHAH
EDHIGAISELWPRLKAPVYATRFAKNLLETRRLSEPGAPKVELREVKPGRRVTVGPFELEYVPVSHSIPESNAIAIRTAA
GLVLHTGDWKIDPTPVAGSVTSPEAFTALGDEGVLAIVCDSTNVVREGFSPSEKTVAETLKTLIADAPHRVAVTTFASNV
ARIRAVAEAAAACGREVIAVGRAMDRVIDVARECGYLDGLPEFRRSDSWKSLPRERVVALLTGSQGEPRAALARVSRRDH
PDISLTAGDQVIFSSRAIPGNERDVGSIINDLIEQGVEVITDRTDLVHVSGHPRRDEMVEMYRWTRPGTAIPVHGEALHL
DEHARFARAQGVQNVVKARNGSLIRLSPGKPEVIDHVKAGRLFKDGDVLIDEKDRAIPERRKLMQAGLVSVAIAIDEDGV
VLGEPAVDIIGLPNRGRSGEPLIETVVDAVSRTLSGMSRGKLKDSESVEKTVDRAVRTAVNEVWGKKPACHVQVVEV

Sequences:

>Translated_557_residues
MVKGQEELVFLPLGGVGEIGMNAALYGFGPEKGRKWIMVDCGMGFAGEEQMPGVDLMFPDLSFIEERRKDLLGIFITHAH
EDHIGAISELWPRLKAPVYATRFAKNLLETRRLSEPGAPKVELREVKPGRRVTVGPFELEYVPVSHSIPESNAIAIRTAA
GLVLHTGDWKIDPTPVAGSVTSPEAFTALGDEGVLAIVCDSTNVVREGFSPSEKTVAETLKTLIADAPHRVAVTTFASNV
ARIRAVAEAAAACGREVIAVGRAMDRVIDVARECGYLDGLPEFRRSDSWKSLPRERVVALLTGSQGEPRAALARVSRRDH
PDISLTAGDQVIFSSRAIPGNERDVGSIINDLIEQGVEVITDRTDLVHVSGHPRRDEMVEMYRWTRPGTAIPVHGEALHL
DEHARFARAQGVQNVVKARNGSLIRLSPGKPEVIDHVKAGRLFKDGDVLIDEKDRAIPERRKLMQAGLVSVAIAIDEDGV
VLGEPAVDIIGLPNRGRSGEPLIETVVDAVSRTLSGMSRGKLKDSESVEKTVDRAVRTAVNEVWGKKPACHVQVVEV
>Mature_557_residues
MVKGQEELVFLPLGGVGEIGMNAALYGFGPEKGRKWIMVDCGMGFAGEEQMPGVDLMFPDLSFIEERRKDLLGIFITHAH
EDHIGAISELWPRLKAPVYATRFAKNLLETRRLSEPGAPKVELREVKPGRRVTVGPFELEYVPVSHSIPESNAIAIRTAA
GLVLHTGDWKIDPTPVAGSVTSPEAFTALGDEGVLAIVCDSTNVVREGFSPSEKTVAETLKTLIADAPHRVAVTTFASNV
ARIRAVAEAAAACGREVIAVGRAMDRVIDVARECGYLDGLPEFRRSDSWKSLPRERVVALLTGSQGEPRAALARVSRRDH
PDISLTAGDQVIFSSRAIPGNERDVGSIINDLIEQGVEVITDRTDLVHVSGHPRRDEMVEMYRWTRPGTAIPVHGEALHL
DEHARFARAQGVQNVVKARNGSLIRLSPGKPEVIDHVKAGRLFKDGDVLIDEKDRAIPERRKLMQAGLVSVAIAIDEDGV
VLGEPAVDIIGLPNRGRSGEPLIETVVDAVSRTLSGMSRGKLKDSESVEKTVDRAVRTAVNEVWGKKPACHVQVVEV

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 60516; Mature: 60516

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKGQEELVFLPLGGVGEIGMNAALYGFGPEKGRKWIMVDCGMGFAGEEQMPGVDLMFPD
CCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCEEECCC
LSFIEERRKDLLGIFITHAHEDHIGAISELWPRLKAPVYATRFAKNLLETRRLSEPGAPK
HHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
VELREVKPGRRVTVGPFELEYVPVSHSIPESNAIAIRTAAGLVLHTGDWKIDPTPVAGSV
EEEEECCCCCEEEECCEEEEEEECCCCCCCCCCEEEEEECCEEEECCCCEECCCCCCCCC
TSPEAFTALGDEGVLAIVCDSTNVVREGFSPSEKTVAETLKTLIADAPHRVAVTTFASNV
CCCHHHHCCCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHH
ARIRAVAEAAAACGREVIAVGRAMDRVIDVARECGYLDGLPEFRRSDSWKSLPRERVVAL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHCCHHHEEEE
LTGSQGEPRAALARVSRRDHPDISLTAGDQVIFSSRAIPGNERDVGSIINDLIEQGVEVI
EECCCCCCHHHHHHHHCCCCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
TDRTDLVHVSGHPRRDEMVEMYRWTRPGTAIPVHGEALHLDEHARFARAQGVQNVVKARN
CCCCCEEEECCCCCHHHHHHHHHHCCCCCEEECCCCEEECHHHHHHHHHHHHHHHHHHCC
GSLIRLSPGKPEVIDHVKAGRLFKDGDVLIDEKDRAIPERRKLMQAGLVSVAIAIDEDGV
CCEEEECCCCCHHHHHHHHCCEEECCCEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCE
VLGEPAVDIIGLPNRGRSGEPLIETVVDAVSRTLSGMSRGKLKDSESVEKTVDRAVRTAV
EECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
NEVWGKKPACHVQVVEV
HHHHCCCCCCEEEEEEC
>Mature Secondary Structure
MVKGQEELVFLPLGGVGEIGMNAALYGFGPEKGRKWIMVDCGMGFAGEEQMPGVDLMFPD
CCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCEEECCC
LSFIEERRKDLLGIFITHAHEDHIGAISELWPRLKAPVYATRFAKNLLETRRLSEPGAPK
HHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
VELREVKPGRRVTVGPFELEYVPVSHSIPESNAIAIRTAAGLVLHTGDWKIDPTPVAGSV
EEEEECCCCCEEEECCEEEEEEECCCCCCCCCCEEEEEECCEEEECCCCEECCCCCCCCC
TSPEAFTALGDEGVLAIVCDSTNVVREGFSPSEKTVAETLKTLIADAPHRVAVTTFASNV
CCCHHHHCCCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHH
ARIRAVAEAAAACGREVIAVGRAMDRVIDVARECGYLDGLPEFRRSDSWKSLPRERVVAL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHCCHHHEEEE
LTGSQGEPRAALARVSRRDHPDISLTAGDQVIFSSRAIPGNERDVGSIINDLIEQGVEVI
EECCCCCCHHHHHHHHCCCCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
TDRTDLVHVSGHPRRDEMVEMYRWTRPGTAIPVHGEALHLDEHARFARAQGVQNVVKARN
CCCCCEEEECCCCCHHHHHHHHHHCCCCCEEECCCCEEECHHHHHHHHHHHHHHHHHHCC
GSLIRLSPGKPEVIDHVKAGRLFKDGDVLIDEKDRAIPERRKLMQAGLVSVAIAIDEDGV
CCEEEECCCCCHHHHHHHHCCEEECCCEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCE
VLGEPAVDIIGLPNRGRSGEPLIETVVDAVSRTLSGMSRGKLKDSESVEKTVDRAVRTAV
EECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
NEVWGKKPACHVQVVEV
HHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]