| Definition | Methylobacterium radiotolerans JCM 2831 chromosome, complete genome. |
|---|---|
| Accession | NC_010505 |
| Length | 6,077,833 |
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The map label for this gene is comEC [H]
Identifier: 170748439
GI number: 170748439
Start: 2147933
End: 2150215
Strand: Reverse
Name: comEC [H]
Synonym: Mrad2831_2021
Alternate gene names: 170748439
Gene position: 2150215-2147933 (Counterclockwise)
Preceding gene: 170748445
Following gene: 170748437
Centisome position: 35.38
GC content: 78.19
Gene sequence:
>2283_bases ATGCGGCGGATCGGCGCGAGGCGGGCGGGCGGCGCGGTGGCGCTGATCGGCCCGCGCGTCCGAGCCCTCCCGCCCGCCCT ACCGGCGCTCCGCGGCTGGGTCGCCGCCGGTCTCGCCCGCGAGGCCGAGCAGCGCCGGCTGTTCCCCTGGCTGGCAGTGG CCTTCGGCGGCGGGATCCTGGTCTACTTCGCGGCGGCCGACGGCGCGCCGAGCCTGGCCGCGCCCCTGATCGCGGCCGCC CTCGCGCTGGCGCCGGTCCCCGTCCTCGGCGCGCGGCCGGCGGCCCTGGCGGCGGCGCTCGCGGTGGCGGCCGCGCTCCT CGGCTTCGCGGCGGCGACCTGGCGGGTCTCGCAGGTCGCCGCGCCGATCCTGACGCGCACCACGATCGGTCCGCTCGTCG GAACGGTCGAGGCCCTGGACGAGCGCGAGGTCGGCGCCCGGCTGGTGATCCGGGTGGAGAGCTTCGCCGGCCTCGCGCCC GAGGCGCGGCCCGCCCGGGTGCGGGTCTCGTTCCGCAAGACGCCGATCCCGCGCCCCGGGGACGTCGTCGCCGCCACGGC GCGGCTGCTGCCGCCCCCGGAGGCGGCCCGGCCCGGCGGCTACGACTTCGCCCGGGACGCCTACTTCCAGGGGATCGGCG CGGTGGGCTCGCTGGTCGGCGCGGTCACCGTCCGGGCGCCGTCCGAGCCGCCGCCGCTGGGCCTGCGGCTCGCCGCGGCA CTGGACGCGGCCCGCAACGGGCTCACGCGCCGGATCGCGGAGGCCGCCGGCGGCCAGGCGGGCGCGGTGGCGGCGGCCCT GGTGACCGGCAAGCGCGGCCTCATCGGACCGGCGACCAACGACGCGCTCCGCGCCGCGGGCATCTACCACGTGGTGTCGA TCTCGGGCCTCCACATGGTGCTGGCCGCCGGCGTGGTGTTCTGGCTGGTGCGGGCGGTCCTCGCCGCGGTGCCGCTCTGC GCGCTCCTCTGGCCGATCAAGAAGATCGCGGCCGGCTTCGCCATGGTCGGCGTCACCGCCTACTGCGCCTTCTCGGGCTG GGACATCGCGGCCGAGCGCTCGCTGATCATGACCCTGATCATGCTGGGCGCGATCCTGGTGGACCGGCCGGCCCTGTCGA TGCGCAACCTCGCCCTCGCGGCGCTGATCGCGCTCGCCCGGGAGCCGGAGGGCCTGCTCGGCCCGAGCTTCCAGATGTCC TTCGGCGCCGTGGCCGGGCTGATCGCCTGCGCCCGGCTGATCGACGGGCGGCTGTTCGTGCGCCCCGGGGCCGGGCGGAT CGGCCGCCTCGTCGGCACCGGCCTCTCGGCGATCACCGGGACCCTGGCTACGACCCTTGTGGCGCAGGTCGCGACCGCGC CCTTCGCCACCTACCACTTCCAGACGGTTCAGCCCTTCGGCCTCGTCGGCAACGCCCTGACCCTGCCGCTCGTCTCCCTG GCGGTGATGCCCGCCGCGGTAATCGGCTGCCTCGCCTATCCCTTCGCCCTCGACCGGCCGGTCTGGTGGCTGATGGGGCG GGCGGTGGCCGGCATGCTGGTGATCTCGGACTGGATCGCCGGGTTCGAGCGGGCGAGCCTGGTGCTGCCGGCCTTCGGCG CCGCGGCGCTGACCCTGCTGACCGCGGGCCTGCTGCTGGCGACGCTGCCGGCCTCCCGCCTGCGCTGGCTCGCCGTGCCG CCGGTCCTGCTCGGCCTCGTCCTCGCGGCCCGGCCCGACCGCTACGACCTCTACGTCGACCGGCAGGGCGCGGGAGCGGC GGTGCGGGGTCCGGACGGGCGGCTCGCGGCCCTCGGAAGCCCCTCCGGCTTCGTCCTCGAGCAGTGGCTGAAGGCGGACG GTGACGGGCGGCGGCCCGCGGCGCTCATCGTCCGGTCGGGCAGCGGGCGCTGCGACCGGCTCGGCTGCACCGCCCGGCTG CCGGACGGGCGGGCGGTCGCCCTCGTCCGGGACAGGCGGGCCTTCCCGGAGGATTGCGCCCGCGCCGCGGTGCTGATCAC CTTCCTCGCGGCGCCGCCGACCTGCACGGGCCCCCTGGTGATCGATCGGCAAGTCCTCGCCGCCCGCGGGGCCGTGGCCC TCCGGGCCGACGGCGACGGCTTCGCCGCGCGCTTCGCCCGGGACGACGGGCGCGCCGTGCCCTGGCGGCCGGCCCCGGGA CGCGATCCGGGACCGCCGCGGCCGGTCACCGCGGAGCCAGGCGACCGCGCCGCGGAGGACGGGGCCGCCGCGCCGGGCGG AGACCTCGCTCCCGGCGACGCGCCGGCCGAGCCGCTTCAGTAG
Upstream 100 bases:
>100_bases CACGAAGAGCCGGCTGTAGCACGGGCCGGCGGATGCGTTAAGAATCGCCCGCAGAATCGCTCGGCCCCGACGACAGGTCG CGCGGAGCGGGGCGGCGGCG
Downstream 100 bases:
>100_bases CGGCGGACGAGGCTGACGAGGCGGCCCTGGATCCGGACCCGGTCGGGCCCGAGCACGCGGGTCTCGTAGGCCGGGTTGGC GGCCTCCAGGGCGATCGAGG
Product: ComEC/Rec2-like protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 760; Mature: 760
Protein sequence:
>760_residues MRRIGARRAGGAVALIGPRVRALPPALPALRGWVAAGLAREAEQRRLFPWLAVAFGGGILVYFAAADGAPSLAAPLIAAA LALAPVPVLGARPAALAAALAVAAALLGFAAATWRVSQVAAPILTRTTIGPLVGTVEALDEREVGARLVIRVESFAGLAP EARPARVRVSFRKTPIPRPGDVVAATARLLPPPEAARPGGYDFARDAYFQGIGAVGSLVGAVTVRAPSEPPPLGLRLAAA LDAARNGLTRRIAEAAGGQAGAVAAALVTGKRGLIGPATNDALRAAGIYHVVSISGLHMVLAAGVVFWLVRAVLAAVPLC ALLWPIKKIAAGFAMVGVTAYCAFSGWDIAAERSLIMTLIMLGAILVDRPALSMRNLALAALIALAREPEGLLGPSFQMS FGAVAGLIACARLIDGRLFVRPGAGRIGRLVGTGLSAITGTLATTLVAQVATAPFATYHFQTVQPFGLVGNALTLPLVSL AVMPAAVIGCLAYPFALDRPVWWLMGRAVAGMLVISDWIAGFERASLVLPAFGAAALTLLTAGLLLATLPASRLRWLAVP PVLLGLVLAARPDRYDLYVDRQGAGAAVRGPDGRLAALGSPSGFVLEQWLKADGDGRRPAALIVRSGSGRCDRLGCTARL PDGRAVALVRDRRAFPEDCARAAVLITFLAAPPTCTGPLVIDRQVLAARGAVALRADGDGFAARFARDDGRAVPWRPAPG RDPGPPRPVTAEPGDRAAEDGAAAPGGDLAPGDAPAEPLQ
Sequences:
>Translated_760_residues MRRIGARRAGGAVALIGPRVRALPPALPALRGWVAAGLAREAEQRRLFPWLAVAFGGGILVYFAAADGAPSLAAPLIAAA LALAPVPVLGARPAALAAALAVAAALLGFAAATWRVSQVAAPILTRTTIGPLVGTVEALDEREVGARLVIRVESFAGLAP EARPARVRVSFRKTPIPRPGDVVAATARLLPPPEAARPGGYDFARDAYFQGIGAVGSLVGAVTVRAPSEPPPLGLRLAAA LDAARNGLTRRIAEAAGGQAGAVAAALVTGKRGLIGPATNDALRAAGIYHVVSISGLHMVLAAGVVFWLVRAVLAAVPLC ALLWPIKKIAAGFAMVGVTAYCAFSGWDIAAERSLIMTLIMLGAILVDRPALSMRNLALAALIALAREPEGLLGPSFQMS FGAVAGLIACARLIDGRLFVRPGAGRIGRLVGTGLSAITGTLATTLVAQVATAPFATYHFQTVQPFGLVGNALTLPLVSL AVMPAAVIGCLAYPFALDRPVWWLMGRAVAGMLVISDWIAGFERASLVLPAFGAAALTLLTAGLLLATLPASRLRWLAVP PVLLGLVLAARPDRYDLYVDRQGAGAAVRGPDGRLAALGSPSGFVLEQWLKADGDGRRPAALIVRSGSGRCDRLGCTARL PDGRAVALVRDRRAFPEDCARAAVLITFLAAPPTCTGPLVIDRQVLAARGAVALRADGDGFAARFARDDGRAVPWRPAPG RDPGPPRPVTAEPGDRAAEDGAAAPGGDLAPGDAPAEPLQ >Mature_760_residues MRRIGARRAGGAVALIGPRVRALPPALPALRGWVAAGLAREAEQRRLFPWLAVAFGGGILVYFAAADGAPSLAAPLIAAA LALAPVPVLGARPAALAAALAVAAALLGFAAATWRVSQVAAPILTRTTIGPLVGTVEALDEREVGARLVIRVESFAGLAP EARPARVRVSFRKTPIPRPGDVVAATARLLPPPEAARPGGYDFARDAYFQGIGAVGSLVGAVTVRAPSEPPPLGLRLAAA LDAARNGLTRRIAEAAGGQAGAVAAALVTGKRGLIGPATNDALRAAGIYHVVSISGLHMVLAAGVVFWLVRAVLAAVPLC ALLWPIKKIAAGFAMVGVTAYCAFSGWDIAAERSLIMTLIMLGAILVDRPALSMRNLALAALIALAREPEGLLGPSFQMS FGAVAGLIACARLIDGRLFVRPGAGRIGRLVGTGLSAITGTLATTLVAQVATAPFATYHFQTVQPFGLVGNALTLPLVSL AVMPAAVIGCLAYPFALDRPVWWLMGRAVAGMLVISDWIAGFERASLVLPAFGAAALTLLTAGLLLATLPASRLRWLAVP PVLLGLVLAARPDRYDLYVDRQGAGAAVRGPDGRLAALGSPSGFVLEQWLKADGDGRRPAALIVRSGSGRCDRLGCTARL PDGRAVALVRDRRAFPEDCARAAVLITFLAAPPTCTGPLVIDRQVLAARGAVALRADGDGFAARFARDDGRAVPWRPAPG RDPGPPRPVTAEPGDRAAEDGAAAPGGDLAPGDAPAEPLQ
Specific function: The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding [H]
COG id: COG0658
COG function: function code R; Predicted membrane metal-binding protein
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: To H.influenzae REC2, N.gonorrhoeae ComA and E.coli YcaI [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001279 - InterPro: IPR004477 - InterPro: IPR004797 [H]
Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]
EC number: NA
Molecular weight: Translated: 77941; Mature: 77941
Theoretical pI: Translated: 11.34; Mature: 11.34
Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRRIGARRAGGAVALIGPRVRALPPALPALRGWVAAGLAREAEQRRLFPWLAVAFGGGIL CCCCCCCCCCCEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE VYFAAADGAPSLAAPLIAAALALAPVPVLGARPAALAAALAVAAALLGFAAATWRVSQVA EEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH APILTRTTIGPLVGTVEALDEREVGARLVIRVESFAGLAPEARPARVRVSFRKTPIPRPG HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCCCEEEEEEECCCCCCCC DVVAATARLLPPPEAARPGGYDFARDAYFQGIGAVGSLVGAVTVRAPSEPPPLGLRLAAA CHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHH LDAARNGLTRRIAEAAGGQAGAVAAALVTGKRGLIGPATNDALRAAGIYHVVSISGLHMV HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH LAAGVVFWLVRAVLAAVPLCALLWPIKKIAAGFAMVGVTAYCAFSGWDIAAERSLIMTLI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH MLGAILVDRPALSMRNLALAALIALAREPEGLLGPSFQMSFGAVAGLIACARLIDGRLFV HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEE RPGAGRIGRLVGTGLSAITGTLATTLVAQVATAPFATYHFQTVQPFGLVGNALTLPLVSL ECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHCCCHHHHHHHHH AVMPAAVIGCLAYPFALDRPVWWLMGRAVAGMLVISDWIAGFERASLVLPAFGAAALTLL HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHH TAGLLLATLPASRLRWLAVPPVLLGLVLAARPDRYDLYVDRQGAGAAVRGPDGRLAALGS HHHHHHHHCCHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCCEEECCCCCEEEECC PSGFVLEQWLKADGDGRRPAALIVRSGSGRCDRLGCTARLPDGRAVALVRDRRAFPEDCA CCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEECCCCCEEEEEECCCCCHHHHH RAAVLITFLAAPPTCTGPLVIDRQVLAARGAVALRADGDGFAARFARDDGRAVPWRPAPG HHHHHHHHHCCCCCCCCCEEECHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCCCCCCC RDPGPPRPVTAEPGDRAAEDGAAAPGGDLAPGDAPAEPLQ CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MRRIGARRAGGAVALIGPRVRALPPALPALRGWVAAGLAREAEQRRLFPWLAVAFGGGIL CCCCCCCCCCCEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE VYFAAADGAPSLAAPLIAAALALAPVPVLGARPAALAAALAVAAALLGFAAATWRVSQVA EEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH APILTRTTIGPLVGTVEALDEREVGARLVIRVESFAGLAPEARPARVRVSFRKTPIPRPG HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCCCEEEEEEECCCCCCCC DVVAATARLLPPPEAARPGGYDFARDAYFQGIGAVGSLVGAVTVRAPSEPPPLGLRLAAA CHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHH LDAARNGLTRRIAEAAGGQAGAVAAALVTGKRGLIGPATNDALRAAGIYHVVSISGLHMV HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH LAAGVVFWLVRAVLAAVPLCALLWPIKKIAAGFAMVGVTAYCAFSGWDIAAERSLIMTLI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH MLGAILVDRPALSMRNLALAALIALAREPEGLLGPSFQMSFGAVAGLIACARLIDGRLFV HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEE RPGAGRIGRLVGTGLSAITGTLATTLVAQVATAPFATYHFQTVQPFGLVGNALTLPLVSL ECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHCCCHHHHHHHHH AVMPAAVIGCLAYPFALDRPVWWLMGRAVAGMLVISDWIAGFERASLVLPAFGAAALTLL HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHH TAGLLLATLPASRLRWLAVPPVLLGLVLAARPDRYDLYVDRQGAGAAVRGPDGRLAALGS HHHHHHHHCCHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCCEEECCCCCEEEECC PSGFVLEQWLKADGDGRRPAALIVRSGSGRCDRLGCTARLPDGRAVALVRDRRAFPEDCA CCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEECCCCCEEEEEECCCCCHHHHH RAAVLITFLAAPPTCTGPLVIDRQVLAARGAVALRADGDGFAARFARDDGRAVPWRPAPG HHHHHHHHHCCCCCCCCCEEECHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCCCCCCC RDPGPPRPVTAEPGDRAAEDGAAAPGGDLAPGDAPAEPLQ CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7968523; 8969508; 9384377 [H]